Welcome!

News Feed Item

Evogene Announces Successful Pilot Program Validating New Source of Novel Genes for Plant Trait Improvement

Long Non-Coding RNA ("lncRNA") Demonstrates Key Role in Determining Plant Traits; Evogene Now Validating Dozens of Novel lncRNA Related Genes Under Various Growth Conditions

REHOVOT, ISRAEL -- (Marketwire) -- 11/26/12 -- Evogene Ltd. (TASE: EVGN), a leading developer of improved plant traits for the food, feed and biofuel industries, announced today the successful completion of a two year pilot program for development and validation of a discovery platform targeted at the identification and use of long non-coding RNA ("lncRNA") related genes for plant trait improvement. Initiated during 2011, the pilot program utilized state-of-the-art high throughput sequencing methodologies to produce a vast amount of genomic data. This data was then analyzed using the Company's proprietary computational genomic technologies in order to identify, assemble and characterize novel lncRNAs, their related genes, and their effect on key plant traits. At present, dozens of these lncRNA related genes are being validated by Evogene under various growth conditions.

lncRNA is the largest subgroup within ncRNA and exists in high abundance in plant species. Transcribed from DNA regions, previously known as 'junk DNA', and not coding proteins, these molecules are now recognized as having key roles in determining many of the complex characteristics which play significant roles in plant traits. Therefore lncRNA represents a largely unexplored world of genetic variation both within and between species and provides Evogene with an anticipated additional rich source for novel genes for plant improvement.

Evogene's core capabilities and competitive advantages relate to identification and utilization of genes effecting key plant traits. To date, the source for identification of such genes, for Evogene and in general, for the rest of the industry, has focused on DNA regions that encode for proteins. Although, this research area continues to provide Evogene with substantial opportunities for identifying novel genes, the addition of lncRNA related genes as a further significant new gene source, is anticipated to take Evogene's world leading agbio discovery efforts to a new level.

Four objectives were achieved in the course of the successful pilot program: the creation of a substantial highly accurate lncRNA genomic data base from a number of different plant species; the development of a discovery platform for accurate identification of lncRNAs and related genes from this data base; linking of these lncRNAs to specific plant traits; and experimental proof, through the use of Evogene's model plant validation system, that lncRNA originating from one plant species can significantly affect traits in other plant species.

"As a world leader in developing improved plant traits based on coding genes, which has yielded impressive and growing R&D pipelines of beneficial plant traits for ourselves and our partners, we have now set a goal for Evogene to be a leader in the largely unexplored, but very promising, field of long non-coding RNA as well," stated Dr. Hagai Karchi, Evogene's EVP Development and CTO. "lncRNA is an innovative research field which has great potential for improving key plant traits. Furthermore, we believe this new 'gene reservoir' will provide a substantial opportunity for discovery and beneficial modification of additional plant traits beyond those currently identified, for both internal development and collaboration with our agbio partners."

An Introduction to DNA, Genes and RNA

  • DNA (deoxyribonucleic acid) contains the complete "blueprint" for each living organism.
  • Regions of DNA that transcribe (i.e. produce) RNA (ribonucleic acid) are termed "genes".
  • Each RNA can either encode (i.e. produce) a protein (messenger RNA or "mRNA"), or not encode ("ncRNA").
  • ncRNA has various subgroups such as long non-coding RNA ("lncRNA"), micro RNA ("miRNA") and small interfering RNA ("siRNA").
  • The largest subgroup currently known in the plant kingdom is lncRNA.
  • To date, most commercial efforts worldwide has focused on mRNA, the related genes and the resulting proteins.

About Evogene
Evogene is a world leading discoverer and developer of improved plant traits through the use of integrated plant genomics. Combining proprietary state-of-the-art computational genomic technologies with advanced breeding methods, the company's discovery infrastructure provides a complete solution for plant trait improvement to its four market focused operating divisions: Yield and abiotic stress, Biotic stress, Ag-chemicals and Biofuels. In addition to its internal programs, Evogene is collaborating with world leading seed companies to introduce its improved plant traits into key commercial crops under milestone and royalty bearing agreements. Evogene, listed for trading on the Tel Aviv Stock Exchange (TASE: EVGN), is headquartered in Rehovot, with field operations in Israel, Brazil and Argentina. For additional information, please visit Evogene's website at www.evogene.com

This press release contains "forward-looking statements" relating to future events. These statements may be identified by words such as "may", "expects", "intends", "anticipates", "plans", "believes", "scheduled", "estimates" or words of similar meaning. Such statements are based on current expectations, estimates, projections and assumptions, describe opinions about future events, involve certain risks and uncertainties which are difficult to predict and are not guarantees of future performance. Therefore, actual future results, performance or achievements of Evogene may differ materially from what is expressed or implied by such forward-looking statements due to a variety of factors, many of which beyond Evogene's control, including, without limitation, those risk factors contained in Evogene's reports filed with the Israeli Securities Authority. Evogene disclaims any obligation or commitment to update these forward-looking statements to reflect future events or developments or changes in expectations, estimates, projections and assumptions.

Contact Information
Evogene:
Efrat Barak Zadok
IR&PR Associate
E-mail: Email Contact
Tel: +972-8-931-1940

More Stories By Marketwired .

Copyright © 2009 Marketwired. All rights reserved. All the news releases provided by Marketwired are copyrighted. Any forms of copying other than an individual user's personal reference without express written permission is prohibited. Further distribution of these materials is strictly forbidden, including but not limited to, posting, emailing, faxing, archiving in a public database, redistributing via a computer network or in a printed form.

Latest Stories
"Cloud Academy is an enterprise training platform for the cloud, specifically public clouds. We offer guided learning experiences on AWS, Azure, Google Cloud and all the surrounding methodologies and technologies that you need to know and your teams need to know in order to leverage the full benefits of the cloud," explained Alex Brower, VP of Marketing at Cloud Academy, in this SYS-CON.tv interview at 21st Cloud Expo, held Oct 31 – Nov 2, 2017, at the Santa Clara Convention Center in Santa Clar...
In his session at 21st Cloud Expo, Carl J. Levine, Senior Technical Evangelist for NS1, will objectively discuss how DNS is used to solve Digital Transformation challenges in large SaaS applications, CDNs, AdTech platforms, and other demanding use cases. Carl J. Levine is the Senior Technical Evangelist for NS1. A veteran of the Internet Infrastructure space, he has over a decade of experience with startups, networking protocols and Internet infrastructure, combined with the unique ability to it...
While some developers care passionately about how data centers and clouds are architected, for most, it is only the end result that matters. To the majority of companies, technology exists to solve a business problem, and only delivers value when it is solving that problem. 2017 brings the mainstream adoption of containers for production workloads. In his session at 21st Cloud Expo, Ben McCormack, VP of Operations at Evernote, discussed how data centers of the future will be managed, how the p...
"NetApp is known as a data management leader but we do a lot more than just data management on-prem with the data centers of our customers. We're also big in the hybrid cloud," explained Wes Talbert, Principal Architect at NetApp, in this SYS-CON.tv interview at 21st Cloud Expo, held Oct 31 – Nov 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA.
"Akvelon is a software development company and we also provide consultancy services to folks who are looking to scale or accelerate their engineering roadmaps," explained Jeremiah Mothersell, Marketing Manager at Akvelon, in this SYS-CON.tv interview at 21st Cloud Expo, held Oct 31 – Nov 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA.
"We're focused on how to get some of the attributes that you would expect from an Amazon, Azure, Google, and doing that on-prem. We believe today that you can actually get those types of things done with certain architectures available in the market today," explained Steve Conner, VP of Sales at Cloudistics, in this SYS-CON.tv interview at 21st Cloud Expo, held Oct 31 – Nov 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA.
"Space Monkey by Vivent Smart Home is a product that is a distributed cloud-based edge storage network. Vivent Smart Home, our parent company, is a smart home provider that places a lot of hard drives across homes in North America," explained JT Olds, Director of Engineering, and Brandon Crowfeather, Product Manager, at Vivint Smart Home, in this SYS-CON.tv interview at @ThingsExpo, held Oct 31 – Nov 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA.
It is of utmost importance for the future success of WebRTC to ensure that interoperability is operational between web browsers and any WebRTC-compliant client. To be guaranteed as operational and effective, interoperability must be tested extensively by establishing WebRTC data and media connections between different web browsers running on different devices and operating systems. In his session at WebRTC Summit at @ThingsExpo, Dr. Alex Gouaillard, CEO and Founder of CoSMo Software, presented ...
Enterprises are adopting Kubernetes to accelerate the development and the delivery of cloud-native applications. However, sharing a Kubernetes cluster between members of the same team can be challenging. And, sharing clusters across multiple teams is even harder. Kubernetes offers several constructs to help implement segmentation and isolation. However, these primitives can be complex to understand and apply. As a result, it’s becoming common for enterprises to end up with several clusters. Thi...
"There's plenty of bandwidth out there but it's never in the right place. So what Cedexis does is uses data to work out the best pathways to get data from the origin to the person who wants to get it," explained Simon Jones, Evangelist and Head of Marketing at Cedexis, in this SYS-CON.tv interview at 21st Cloud Expo, held Oct 31 – Nov 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA.
WebRTC is great technology to build your own communication tools. It will be even more exciting experience it with advanced devices, such as a 360 Camera, 360 microphone, and a depth sensor camera. In his session at @ThingsExpo, Masashi Ganeko, a manager at INFOCOM Corporation, introduced two experimental projects from his team and what they learned from them. "Shotoku Tamago" uses the robot audition software HARK to track speakers in 360 video of a remote party. "Virtual Teleport" uses a multip...
"We work around really protecting the confidentiality of information, and by doing so we've developed implementations of encryption through a patented process that is known as superencipherment," explained Richard Blech, CEO of Secure Channels Inc., in this SYS-CON.tv interview at 21st Cloud Expo, held Oct 31 – Nov 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA.
High-velocity engineering teams are applying not only continuous delivery processes, but also lessons in experimentation from established leaders like Amazon, Netflix, and Facebook. These companies have made experimentation a foundation for their release processes, allowing them to try out major feature releases and redesigns within smaller groups before making them broadly available. In his session at 21st Cloud Expo, Brian Lucas, Senior Staff Engineer at Optimizely, discussed how by using ne...
The question before companies today is not whether to become intelligent, it’s a question of how and how fast. The key is to adopt and deploy an intelligent application strategy while simultaneously preparing to scale that intelligence. In her session at 21st Cloud Expo, Sangeeta Chakraborty, Chief Customer Officer at Ayasdi, provided a tactical framework to become a truly intelligent enterprise, including how to identify the right applications for AI, how to build a Center of Excellence to oper...
"IBM is really all in on blockchain. We take a look at sort of the history of blockchain ledger technologies. It started out with bitcoin, Ethereum, and IBM evaluated these particular blockchain technologies and found they were anonymous and permissionless and that many companies were looking for permissioned blockchain," stated René Bostic, Technical VP of the IBM Cloud Unit in North America, in this SYS-CON.tv interview at 21st Cloud Expo, held Oct 31 – Nov 2, 2017, at the Santa Clara Conventi...