|By PR Newswire||
|November 27, 2012 06:06 PM EST||
LONDON, Nov. 27, 2012 /PRNewswire/ -- The World Health Organization (WHO) last week reported that four new cases of SARS-like virus have been found in Saudi Arabia and Qatar, and the Department of Health in Singapore reported one additional case, adding to the two cases from the Middle East reported in late September. When the first two cases were reported, BioRadar UK Ltd., a biotechnology company focused on predicting and preventing viral pandemics, published data on October 5th showing a rise in the genomic Replikin™Count of the Human SARS Virus to the same levels of 2002 that preceded the lethal 2003 SARS outbreak.
At a seminar given today at the Healthcare Emergency Management Program, Boston University School of Medicine, Dr. Samuel Bogoch, Senior Distinguished Scholar at the BU School of Medicine, stated that the recent WHO and Singapore reports, coupled with the rise of the genomic Replikin Count to the same elevated range found in 2002 before the 2003 SARS outbreak, have prompted renewed calls for immediate trials of newly available synthetic Replikin™Vaccine, specifically developed for this unique viral strain.
An analysis of the current virus's genomic Replikin Count has revealed the Count to be increased significantly above the preceding low "resting" levels 2004-2011. The identification of the modified virus as responsible for new cases of SARS-like respiratory virus has raised concerns over the risk of the disease spreading (1). These concerns may be justified given the observed rise in virus's genomic Replikin™ Count.
Currently, the Replikin Counts in several genomic areas of "human betacoronavirus 2c EMC/2012" are 2.6, 3.5, 3.9 and 8.5. The Figure shows that the previous low Counts between 1995 and 2001 preceded the three-fold increase in 2002 to a mean of 4.5 (+/-3), which was followed in 2003 by a SARS outbreak with 8,000 cases and 774 deaths.
While a few sporadic human SARS-like cases with high Replikin Counts "do not an outbreak make," elevated genomic Replikin Counts of H1N1 observed in only two sporadic cases reported on Pubmed from Mexico in each of 2003, 2006, 2007 and 2008, presaged the onset in Mexico of the H1N1 Pandemic of 2009 (3).
The established pattern of genomic Replikin Counts increasing to high levels, accompanied by sporadic lethal human cases, followed by an outbreak of rapidly replicating spreading lethal human disease, was also found in six other correct predictions in influenza made one to two years in advance (4, 5). The geographic locations of these outbreaks were also specified, as in lethal outbreaks of H5N1 in 2006-2007 in Indonesia, and currently in Cambodia. Similarly, the highest Replikin Counts in Foot and Mouth Disease (FMD) virus in 52 years (2) predicted the current outbreaks of FMD in Asia and the Middle East one year in advance.
It is unusual for two currently lethal viruses with rising Replikin Counts, namely H5N1 and the SARS-like viruses, to be of concern at the same time with regard to further spread as outbreaks or pandemics. The possibility of preventing the development of influenza and coronavirus virus outbreaks and pandemics is being considered for the first time because quantitative changes in the genome have been shown in seven instances to predict strain-specific outbreaks and the particular geographic locations where outbreaks will occur (2-5).
The observation of increasing Replikin Counts provides time to prepare an optimal public health response, time to prepare vaccines and other therapies specific to the oncoming organism, in sufficient quantity, and time to adequately test and distribute the vaccine before the hit-and-run outbreak has begun to disappear as happened in 2009 (2-4).
In addition, the new Replikins synthetic vaccines provide distinct advantages over traditional vaccines. They are tailored to the specific Replikins in the current threatening organism, solid-phase synthesized completely free of biologicals, thus containing no bio-contaminants, synthesized in seven days instead of eight months, and effective when shipped freeze-dried, not requiring refrigeration, and at an estimated cost for 7 billion people of 10 cents per person compared with the cost of $14 per person for the biological vaccines purchased for the 2009 influenza pandemic (USA GAO).
The Replikins data suggests that any vaccines, which might be active against H5N1 (such as SyntheticReplikin™TransFluVaccine2012) and against the SARS-like virus (such as SyntheticReplikin™VaccineSARS 2012), should be produced and tested as soon as possible. For these reasons, Replikins, Ltd. is announcing that both of these vaccines are now available for testing by government health agencies and medical schools.
Contact: Replikins 646-320-5910; [email protected]
1. Roos, Robert. CIDRAP news, September 25, 2012 on Human betacoronavirus 2c EMC/2012,
van Boheemen,S. et al GenBank: JX869059.1
2. Bogoch, S. and Bogoch, E.S. Genome Replikin Count™ Predicts Increased Infectivity/Lethality of Viruses. Nature Precedings npre20127144. O4 April 2012.
3. Bogoch, S. and Bogoch, E.S. Prediction of specific virus outbreaks made from the increased concentration of a new class of virus genomic peptides, replikins. Nature Precedings doi:10.1038/npre.2011.6279.1.23 Aug 2011.
4. Bogoch,S. and Bogoch, ES. Bogoch Replikins Pandemic Prevention: Increase of Strain-Specific Influenza Genomic Replikin Counts, Having Predicted Outbreaks and their Location Seven Times Consecutively, Up to Two Years in Advance, Provides Time for Prevention of Pandemics. Nature Precedings.doi:10.1038/npre.2012.6952.1 01 March, 2012
5. UN Food and Agriculture Organization (FAO) discussion of Replikins, DVM Newsmagazine, (Sept. 8, 2011). Reproduced in Report #42 , Replikins.com
This press release was issued through eReleases® Press Release Distribution. For more information, visit http://www.ereleases.com.
For basic one-to-one voice or video calling solutions, WebRTC has proven to be a very powerful technology. Although WebRTC’s core functionality is to provide secure, real-time p2p media streaming, leveraging native platform features and server-side components brings up new communication capabilities for web and native mobile applications, allowing for advanced multi-user use cases such as video broadcasting, conferencing, and media recording.
Feb. 24, 2017 11:30 PM EST Reads: 6,387
SYS-CON Events announced today that delaPlex will exhibit at SYS-CON's @CloudExpo, which will take place on June 6-8, 2017, at the Javits Center in New York City, NY. delaPlex pioneered Software Development as a Service (SDaaS), which provides scalable resources to build, test, and deploy software. It’s a fast and more reliable way to develop a new product or expand your in-house team.
Feb. 24, 2017 10:30 PM EST Reads: 1,757
Extreme Computing is the ability to leverage highly performant infrastructure and software to accelerate Big Data, machine learning, HPC, and Enterprise applications. High IOPS Storage, low-latency networks, in-memory databases, GPUs and other parallel accelerators are being used to achieve faster results and help businesses make better decisions. In his session at 18th Cloud Expo, Michael O'Neill, Strategic Business Development at NVIDIA, focused on some of the unique ways extreme computing is...
Feb. 24, 2017 09:30 PM EST Reads: 8,370
The explosion of new web/cloud/IoT-based applications and the data they generate are transforming our world right before our eyes. In this rush to adopt these new technologies, organizations are often ignoring fundamental questions concerning who owns the data and failing to ask for permission to conduct invasive surveillance of their customers. Organizations that are not transparent about how their systems gather data telemetry without offering shared data ownership risk product rejection, regu...
Feb. 24, 2017 09:15 PM EST Reads: 1,574
SYS-CON Events announced today that CA Technologies has been named "Platinum Sponsor" of SYS-CON's 20th International Cloud Expo®, which will take place on June 6-8, 2017, at the Javits Center in New York City, New York, and 21st International Cloud Expo, which will take place in November in Silicon Valley, California.
Feb. 24, 2017 09:00 PM EST Reads: 2,009
"We got started as search consultants. On the services side of the business we have help organizations save time and save money when they hit issues that everyone more or less hits when their data grows," noted Otis Gospodnetić, Founder of Sematext, in this SYS-CON.tv interview at @DevOpsSummit, held June 9-11, 2015, at the Javits Center in New York City.
Feb. 24, 2017 08:45 PM EST Reads: 5,868
WebRTC is about the data channel as much as about video and audio conferencing. However, basically all commercial WebRTC applications have been built with a focus on audio and video. The handling of “data” has been limited to text chat and file download – all other data sharing seems to end with screensharing. What is holding back a more intensive use of peer-to-peer data? In her session at @ThingsExpo, Dr Silvia Pfeiffer, WebRTC Applications Team Lead at National ICT Australia, looked at differ...
Feb. 24, 2017 08:45 PM EST Reads: 6,842
"Peak 10 is a national cloud data center solutions managed services provider, and part of that is disaster recovery. We see a growing trend in the industry where companies are coming to us looking for assistance in their DR strategy," stated Andrew Cole, Director of Solutions Engineering at Peak 10, in this SYS-CON.tv interview at 18th Cloud Expo, held June 7-9, 2016, at the Javits Center in New York City, NY.
Feb. 24, 2017 08:15 PM EST Reads: 5,641
In his General Session at DevOps Summit, Asaf Yigal, Co-Founder & VP of Product at Logz.io, explored the value of Kibana 4 for log analysis and provided a hands-on tutorial on how to set up Kibana 4 and get the most out of Apache log files. He examined three use cases: IT operations, business intelligence, and security and compliance. Asaf Yigal is co-founder and VP of Product at log analytics software company Logz.io. In the past, he was co-founder of social-trading platform Currensee, which w...
Feb. 24, 2017 08:15 PM EST Reads: 5,307
With major technology companies and startups seriously embracing IoT strategies, now is the perfect time to attend @ThingsExpo 2016 in New York. Learn what is going on, contribute to the discussions, and ensure that your enterprise is as "IoT-Ready" as it can be! Internet of @ThingsExpo, taking place June 6-8, 2017, at the Javits Center in New York City, New York, is co-located with 20th Cloud Expo and will feature technical sessions from a rock star conference faculty and the leading industry p...
Feb. 24, 2017 08:15 PM EST Reads: 1,713
Cloud Expo, Inc. has announced today that Andi Mann returns to 'DevOps at Cloud Expo 2017' as Conference Chair The @DevOpsSummit at Cloud Expo will take place on June 6-8, 2017, at the Javits Center in New York City, NY. "DevOps is set to be one of the most profound disruptions to hit IT in decades," said Andi Mann. "It is a natural extension of cloud computing, and I have seen both firsthand and in independent research the fantastic results DevOps delivers. So I am excited to help the great t...
Feb. 24, 2017 07:45 PM EST Reads: 3,974
The Internet of Things can drive efficiency for airlines and airports. In their session at @ThingsExpo, Shyam Varan Nath, Principal Architect with GE, and Sudip Majumder, senior director of development at Oracle, discussed the technical details of the connected airline baggage and related social media solutions. These IoT applications will enhance travelers' journey experience and drive efficiency for the airlines and the airports.
Feb. 24, 2017 06:15 PM EST Reads: 1,858
In his keynote at @ThingsExpo, Chris Matthieu, Director of IoT Engineering at Citrix and co-founder and CTO of Octoblu, focused on building an IoT platform and company. He provided a behind-the-scenes look at Octoblu’s platform, business, and pivots along the way (including the Citrix acquisition of Octoblu).
Feb. 24, 2017 06:15 PM EST Reads: 1,565
A look across the tech landscape at the disruptive technologies that are increasing in prominence and speculate as to which will be most impactful for communications – namely, AI and Cloud Computing. In his session at 20th Cloud Expo, Curtis Peterson, VP of Operations at RingCentral, will highlight the current challenges of these transformative technologies and share strategies for preparing your organization for these changes. This “view from the top” will outline the latest trends and developm...
Feb. 24, 2017 06:00 PM EST Reads: 2,358
SYS-CON Events announced today that Technologic Systems Inc., an embedded systems solutions company, will exhibit at SYS-CON's @ThingsExpo, which will take place on June 6-8, 2017, at the Javits Center in New York City, NY. Technologic Systems is an embedded systems company with headquarters in Fountain Hills, Arizona. They have been in business for 32 years, helping more than 8,000 OEM customers and building over a hundred COTS products that have never been discontinued. Technologic Systems’ pr...
Feb. 24, 2017 05:30 PM EST Reads: 3,575