Welcome!

News Feed Item

Eporgen's Portfolio Company Genovax Sells GX301, its Clinical-Stage Therapeutic Vaccine for the Treatment of Various Types of Cancer, to Mediolanum Farmaceutici

MILAN and COLLERETTO GIACOSA, Italy, December 3, 2012 /PRNewswire/ --

Mediolanum Farmaceutici SpA, a privately owned company that leads the Mediolanum Farmaceutici Group of companies, and Genovax srl, a private company which belongs to the portfolio of Eporgen Venture and was originated from the University of Genoa , announced the acquisition by Mediolanum of the global rights to GX301, Genovax's therapeutic vaccine to treat various types of cancer.  The first clinical study with GX301 was successfully completed earlier this year in prostate and renal cancer patients. Further clinical studies are scheduled to be initiated in the next few months, and all future development and commercialization activities will be the responsibility of Mediolanum with the support of Genovax. Under the agreement, Genovax will receive upfront and milestone payments as well as royalties.  

The acquisition of Genovax's innovative therapeutic vaccine for the treatment of various type of cancer is part of a strategy that we initiated since the late '90s and is a testament to our commitment to Research and Development", said Dr Rinaldo Del Bono, founder and President of Mediolanum Farmaceutici. "The acquisition of GX301 expands the interests of Mediolanum to a new therapeutic area (oncology). We look forward to advancing the development of the product through to its worldwide registration and make it available to cancer patients as soon as possible" added Dr Del Bono.

Dr Domenico Criscuolo, President of Genovax commented: "The agreement with Mediolanum is a remarkable achievement, which confirms the vision of all researchers who trusted in the therapeutic potential of GX301. In only four years Genovax's team was able to consolidate with clinical results the original idea and to attract the interest of Mediolanum, which will lead the further development work. My personal thanks to all Genovax team members, for their dedication and support to GX301 project, and a special acknowledgement to the memory of Silvano Fumero, who shared my enthusiasm for this project, and was instrumental for the foundation of Genovax."

Genovax was founded in March 2008 in Ivrea by Prof. Francesco Indiveri, Prof. Gilberto Filaci, Dr Daniela Fenoglio, Dr Giuseppe Balbi and Dr Domenico Criscuolo, with the financial support of Eporgen Venture. The science behind Genovax's technology was originated at the Centre of Excellence for Biomedical Research (CEBR), which is based at the University of Genoa. Konstantinos Efthymiopoulos, President of Eporgen Venture said: "We are delighted by this event which is the first major transaction of a company in our portfolio. It validates the vision of Eporgen's founder, the late Dr Silvano Fumero, and vindicates the 70 private shareholders of Eporgen who also believed in it and are nurturing innovation, Italian science and scientists and hope that new therapies will eventually emerge through their financial support. We would like to congratulate the Genovax team for bringing GX301 thus far and to wish every success in the further development of the product, hoping that it will become a life saving therapy for cancer patients."  

Further notes for Editors:

About GX301

GX301 is a telomerase-based vaccine against cancer, which completed in February 2012 the first phase I study in prostate and renal cancer patients with very promising results. The study was conducted in Italy and showed that GX301 was very well tolerated and that induced vaccine-specific immune response in all patients. Disease stabilisation was observed in about one third of the patients and overall survival was longer than expected.  GX301 is composed by multiple peptides and adjuvants and is designed to induce potent immune responses that are specific for cancer cells through the activation of both CD4+ and CD8+ T lymphocytes. It is envisaged that GX301 may be useful also in other types of cancer and this will be explored in future clinical studies.

About Genovax

Genovax srl is a privately held company based in Colleretto Giacosa (Torino, Italy) and is focusing on the development of therapeutic vaccines against cancer, such as GX301, or chronic inflammatory diseases such as Systemic Lupus Erythematosus (SLE), where the lead product is GX101.

About Mediolanum Farmaceutici

Mediolanum was founded in 1972 by Dr Rinaldo Del Bono and its headquarters are located in Milan (Italy). It is a private pharmaceutical group that develops, manufactures, promotes and markets ethical pharmaceutical products (internally-developed, acquired or in-licensed) and herbal nutritionals. About 25 products are being commercialized by the Group, to treat cardiovascular, respiratory, inflammatory and dermatological disorders, infections, allergies, epilepsy, anemia and neuropathic pain. The Group currently employs around 570 people and its main commercial activities are concentrated in Italy and France, while sales in other countries are currently obtained through out-licensing and export activities.  

About Eporgen Venture

Eporgen Venture (EV) is an Italian company, entirely funded by private, non-institutional investors, which is dedicated to seed capital investments in the area of life sciences. EV started its operations in 2005 and is based in the Bioparco "Silvano Fumero" in Colleretto Giacosa (Torino, Italy), where it created a portfolio of 11 companies (7 companies developing products and 4 companies developing technologies). These start-up companies are legally independent entities, controlled by EV, and are built around intellectual property that is being developed up to a proof-of-concept stage. The operating model of EV offers the virtues of the "asset-centric" investment model, but also the operating efficiencies of a small, virtual biotech with a centrally managed portfolio, guided by seasoned pharma and biotech executives. Since the start of its operations, EV has experienced a remarkable growth, by doubling the size of its investor base and of its portfolio of companies. Over the next six months EV is expected to complete further transactions and raise capital to advance the development of its assets.

Contacts:
Konstantinos Efthymiopoulos
President, Eporgen Venture SpA
T: +39-0125-561000
[email protected]


SOURCE Eporgen Venture SpA

More Stories By PR Newswire

Copyright © 2007 PR Newswire. All rights reserved. Republication or redistribution of PRNewswire content is expressly prohibited without the prior written consent of PRNewswire. PRNewswire shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.

Latest Stories
Digital innovation is the next big wave of business transformation based on digital technologies of which IoT and Big Data are key components, For example: Business boundary innovation is a challenge to excavate third-party business value using IoT and BigData, like Nest Business structure innovation may propose re-building business structure from scratch, as Uber does in the taxicab industry The social model innovation is also a big challenge to the new social architecture with the design fr...
In this strange new world where more and more power is drawn from business technology, companies are effectively straddling two paths on the road to innovation and transformation into digital enterprises. The first path is the heritage trail – with “legacy” technology forming the background. Here, extant technologies are transformed by core IT teams to provide more API-driven approaches. Legacy systems can restrict companies that are transitioning into digital enterprises. To truly become a lea...
Just over a week ago I received a long and loud sustained applause for a presentation I delivered at this year’s Cloud Expo in Santa Clara. I was extremely pleased with the turnout and had some very good conversations with many of the attendees. Over the next few days I had many more meaningful conversations and was not only happy with the results but also learned a few new things. Here is everything I learned in those three days distilled into three short points.
Whether they’re located in a public, private, or hybrid cloud environment, cloud technologies are constantly evolving. While the innovation is exciting, the end mission of delivering business value and rapidly producing incremental product features is paramount. In his session at @DevOpsSummit at 19th Cloud Expo, Kiran Chitturi, CTO Architect at Sungard AS, will discuss DevOps culture, its evolution of frameworks and technologies, and how it is achieving maturity. He will also cover various st...
Major trends and emerging technologies – from virtual reality and IoT, to Big Data and algorithms – are helping organizations innovate in the digital era. However, to create real business value, IT must think beyond the ‘what’ of digital transformation to the ‘how’ to harness emerging trends, innovation and disruption. Architecture is the key that underpins and ties all these efforts together. In the digital age, it’s important to invest in architecture, extend the enterprise footprint to the cl...
Adobe is changing the world though digital experiences. Adobe helps customers develop and deliver high-impact experiences that differentiate brands, build loyalty, and drive revenue across every screen, including smartphones, computers, tablets and TVs. Adobe content solutions are used daily by millions of companies worldwide-from publishers and broadcasters, to enterprises, marketing agencies and household-name brands. Building on its established design leadership, Adobe enables customers not o...
Data is an unusual currency; it is not restricted by the same transactional limitations as money or people. In fact, the more that you leverage your data across multiple business use cases, the more valuable it becomes to the organization. And the same can be said about the organization’s analytics. In his session at 19th Cloud Expo, Bill Schmarzo, CTO for the Big Data Practice at EMC, will introduce a methodology for capturing, enriching and sharing data (and analytics) across the organizati...
DevOps at Cloud Expo, taking place Nov 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA, is co-located with 19th Cloud Expo and will feature technical sessions from a rock star conference faculty and the leading industry players in the world. The widespread success of cloud computing is driving the DevOps revolution in enterprise IT. Now as never before, development teams must communicate and collaborate in a dynamic, 24/7/365 environment. There is no time to wait for long dev...
IoT offers a value of almost $4 trillion to the manufacturing industry through platforms that can improve margins, optimize operations & drive high performance work teams. By using IoT technologies as a foundation, manufacturing customers are integrating worker safety with manufacturing systems, driving deep collaboration and utilizing analytics to exponentially increased per-unit margins. However, as Benoit Lheureux, the VP for Research at Gartner points out, “IoT project implementers often ...
Why do your mobile transformations need to happen today? Mobile is the strategy that enterprise transformation centers on to drive customer engagement. In his general session at @ThingsExpo, Roger Woods, Director, Mobile Product & Strategy – Adobe Marketing Cloud, covered key IoT and mobile trends that are forcing mobile transformation, key components of a solid mobile strategy and explored how brands are effectively driving mobile change throughout the enterprise.
SYS-CON Events announced today that Bsquare has been named “Silver Sponsor” of SYS-CON's @ThingsExpo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. For more than two decades, Bsquare has helped its customers extract business value from a broad array of physical assets by making them intelligent, connecting them, and using the data they generate to optimize business processes.
In his session at @ThingsExpo, Kausik Sridharabalan, founder and CTO of Pulzze Systems, Inc., will focus on key challenges in building an Internet of Things solution infrastructure. He will shed light on efficient ways of defining interactions within IoT solutions, leading to cost and time reduction. He will also introduce ways to handle data and how one can develop IoT solutions that are lean, flexible and configurable, thus making IoT infrastructure agile and scalable.
Businesses are struggling to manage the information flow and interactions between all of these new devices and things jumping on their network, and the apps and IT systems they control. The data businesses gather is only helpful if they can do something with it. In his session at @ThingsExpo, Chris Witeck, Principal Technology Strategist at Citrix, will discuss how different the impact of IoT will be for large businesses, expanding how IoT will allow large organizations to make their legacy ap...
In his keynote at 18th Cloud Expo, Andrew Keys, Co-Founder of ConsenSys Enterprise, provided an overview of the evolution of the Internet and the Database and the future of their combination – the Blockchain. Andrew Keys is Co-Founder of ConsenSys Enterprise. He comes to ConsenSys Enterprise with capital markets, technology and entrepreneurial experience. Previously, he worked for UBS investment bank in equities analysis. Later, he was responsible for the creation and distribution of life sett...
Video experiences should be unique and exciting! But that doesn’t mean you need to patch all the pieces yourself. Users demand rich and engaging experiences and new ways to connect with you. But creating robust video applications at scale can be complicated, time-consuming and expensive. In his session at @ThingsExpo, Zohar Babin, Vice President of Platform, Ecosystem and Community at Kaltura, will discuss how VPaaS enables you to move fast, creating scalable video experiences that reach your ...