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Global Neurostimulation Industry

NEW YORK, Dec. 5, 2012 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:

Global Neurostimulation Industry

http://www.reportlinker.com/p098270/Global-Neurostimulation-Industry.htm...

This report analyzes the Global markets for Neurostimulation in US$ Million by the following Product Segments: Spinal Cord Stimulators (SCS) {Radio Frequency (RF) System, Implantable Pulse Generator (IPG)}, Deep Brain Stimulators (DBS), Sacral Nerve Stimulators (SNS), and Vagus Nerve Stimulators (VNS). The US market is analyzed both in terms of value (US$) and Volume (Units) for all the above listed Product Segments, and also additionally for Gastric Electric Stimulators (GES). The report provides separate comprehensive analytics for the United States, and Rest of World. Annual estimates and forecasts are provided for the period 2010 through 2018. Also, a six-year historic analysis is provided for these markets. The report profiles 21 companies including many key and niche players such as Boston Scientific Corp., Cyberonics, Inc., Medtronic, Inc., St. Jude Medical, Inc., Synapse Biomedical, Inc., and SPR Therapeutics, LLC. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based upon search engine sources in the public domain.

I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONSStudy Reliability and Reporting Limitations I-1Disclaimers I-2Data Interpretation & Reporting Level I-2Quantitative Techniques & Analytics I-3Product Definitions and Scope of Study I-3Spinal Cord Stimulation (SCS) I-3Radio Frequency (RF) Systems I-4Implantable Pulse Generator Systems (IPGs) I-4Deep Brain Stimulation (DBS) I-4Sacral Nerve Stimulation (SNS) I-4Vagus Nerve Stimulation (VNS) I-4II. EXECUTIVE SUMMARY

1. MARKET SNAPSHOTS II-1

2. MARKET OVERVIEW II-2Rising Demand for Neurostimulation Devices II-2Current and Future Analysis II-3Table 1: Worldwide Neurostimulation Market (2010-2018):Product Segments (Spinal Cord Stimulators, Deep BrainStimulators, Sacral Nerve Stimulators, and Vagus NerveStimulators) Ranked by Growth (includes correspondingGraph/Chart) II-4Neurostimulation Therapy Gets Popular II-5Technological Advancements So Far II-5SCS - The New Painkiller II-5Future Prospects II-5Obesity Control to Spur Market Growth in Future II-6Major Neurostimulation Therapies And Indications At A Glance II-7

3. TRENDS AND ISSUES II-8

Chip Makers Struggle to Meet Quality Demand II-8

Market Growth Attracts New Investors II-8

Neurostimulation on a Rise with Growing Indications II-8

Neurostimulation Market Marked by High Entry Barriers II-8

Increasing Acceptance of Neurostimulation due to Advanced

Clinical Benefits II-9

Powering Neurostimulation Devices-The Key to Success II-9

Market Development Initiatives to Fuel Market Growth II-9

Exploring Market Opportunities - The Technology Way II-10

Neurostimulation Devices - Growing Awareness and Acceptance

Among Physicians II-10

Synergy with Pharma & Biotech Companies Creates New Avenues II-10

Third-Party Reimbursement - A Vital Role to Play II-11

4. COMPETITIVE SCENARIO II-12Few Players Dominate Neurostimulation Market II-12Worldwide Neurostimulation Market: Leading Players byProduct Segment II-12Table 2: Leading Players in the Global NeurostimulationMarket (2011): Percentage Share Breakdown of Value Sales forMedtronic, St. Jude Medical, Boston Scientific, Cyberonicsand Others (includes corresponding Graph/Chart) II-13

Table 3: World Neurostimulation Market (2012): Percentage

Share Breakdown of Value Sales for Pain, Deafness, Epilepsy,

Movement Disorders, Depression, Stroke, Incontinence,

Gastroparesis and Obesity (includes corresponding

Graph/Chart) II-13

Product Offerings of Leading Players in the Neurostimulation

Market II-14

Select Spinal Cord Stimulation Product Offerings of St. Jude

and Medtronic II-14

Stimulation Parameters of Select SCS Products II-15

Companies Researching Neurostimulator Applications by

Indication II-15

5. EMERGING THERAPIES IN NEURO STIMULATION II-16ElectroCore to Demonstrate GammaCore at EHMTIC 2012 II-16University of Alabama Develops DBS Therapy for Parkinson'sDisease II-16California Based Medical Center Innovates Brain-controlledProsthetic Limb II-16Toronto Western Hospital Develops DBS Therapy for AlzheimersDisease II-17SPR Therapeutics Successfully Demonstrates PNS Therapy inStroke Victim II-17

6. NEUROMODULATION INDUSTRY: AN INSIGHT II-18

Attacking the Source of Pain - The Logic behind Neuromodulation II-18

Growth Prospects for Neuromodulation Industry II-18

7. PRODUCT OVERVIEW II-20Introduction to Neurostimulator II-20A Historical Note II-20Neurostimulation Devices by Product Segment II-20Spinal Cord Stimulation (SCS) II-21SCS - What it Treats II-22Segmentation by Type of Power Source II-22Implantable Pulse Generator Systems (IPGs) II-22Radio Frequency (RF) Systems II-22Market Assessment for RF Systems II-23Sacral Nerve Stimulation (SNS) II-23Deep Brain Stimulation (DBS) II-24Vagus Nerve Stimulation (VNS) II-24Gastric Electric Stimulation (GES) II-25Stimulation Device - How it Works II-25Neurostimulation & its Benefits II-25Prospective Application Areas for Neurostimulators - SelectIndications II-26Neurostimulation Indications and Use of Related Devices/Techniques in the US II-27Approved Indications for Spinal Cord Stimulation by GeographicRegions II-27Neurostimulation Devices - Technology & Safety Issues II-27

8. NEUROSTIMULATION DEVICE APPROVALS II-29

SPR™ Therapeutics' SMARTPATCH™ Neurostimulation System

Obtains FDA's IDE Approval II-29

Bioness Receives FDA Clearance for Use of Smaller Leg Cuff

with L300 Foot Drop System II-29

Imthera Medical's AURA6000 Awarded CE Mark for Sleep Apnea

Therapy II-29

Neuronetics' Magnetic Brain Stimulation Device Receives CE

Approval II-30

St. Jude Medical's Eon Mini Stimulator Obtains European CE

Mark Approval II-30

Boston Scientific's Precision Plus SCS Wins FDA Approval for

Limb Pain II-30

Boston Scientific's Infinion™ 16 Percutaneous Lead Obtains CE

Approval II-30

NeuroSigma Obtains CE Approval for Monarch Nerve Stimulation

System II-31

Neurotech's ADNS-300 Neurostimulation Device Obtains CE Mark

Approval II-31

Bioness Bags FDA Approval for NESS L300 Plus, for Managing

Thigh Weakness II-31

Bioness Obtains CE Mark Approval and FDA Clearance For NESS

H200 Hand Rehabilitation System II-31

Boston Scientific's Clik Anchor Obtains FDA Approval II-32

Medtronic's AdaptiveStim RestoreSensor Lands US FDA Approval II-32

Synapse Biomedical Obtains FDA Approval for NeuRx Diaphragm

Pacing System II-32

St Jude Medical's Genesis System Secures CE Mark Approval II-32

St. Jude Receives Approval for Neurostimulation System from

Japanese MHLW II-33

St. Jude Secures European CE Mark Approval for Epiducer™ Lead

Delivery System II-33

St. Jude Medical Obtains TGA Approval for Brio™ DBS System II-33

Boston Scientific Secures FDA Approval for D4 and W4 SCS Lead

Splitters II-33

St. Jude Medical Receives Approval for Penta Neurostimulation

Lead from FDA II-34

St. Jude Receives European CE Mark Approval for LibraXP™ and

Libra® Deep Brain Stimulation Systems II-34

Medtronic Receives FDA Approval for Activa PC and Activa RC

DBS Devices II-34

Medtronic Receives FDA Approval for Reclaim™ Deep Brain

Stimulation Therapy II-34

St. Jude Receives European CE Mark Approval for Genesis®

Neurostimulation System II-35

St. Jude Eon Mini™ Neurostimulator Receives Australian

Therapeutic Goods Administration Approval II-35

Medtronic Receives FDA Approval for Activa® RC, Activa PC DBS

Devices II-35

9. RECENT INDUSTRY ACTIVITY II-37Cyberonics Collaborates with Imricor Medical for DevelopingMRI Compatible Leads II-37Boston Scientific Takes Over Intelect Medical II-37GE Healthcare Inks Distribution and Marketing Agreement withKC BioMedix II-37Cyberonics and ImThera to Develop Neurostimulation Technologyfor OSA II-38NDI Medical Establishes New Business Unit for Advancement ofIPG Technology II-38Sonova Holding Acquires Advanced Bionics II-38Medtronic Initiates Clinical Trial for RestoreSensor II-38NeuroMetrix Purchases Select Assets of CyberkineticsNeurotechnology Systems II-39St. Jude Medical Purchases Non-Cash Assets and IntellectualProperty of Northstar Neuroscience II-39Victhom Human Bionics Signs Agreement with Otto Bock HealthCare II-39Neuros Medical Collaborates with Battelle II-40JumpStart & CTV Invest in Neuros Medical II-40InterWest Invests in Autonomic Technologies II-40MicroTransponder Finalizes Series A Funding Round forWireless Neurostimulator Development II-41

10. PRODUCT INNOVATIONS/INTRODUCTIONS II-42

Bioness Launches L300 Plus Foot Drop System in the US For

Patients with Gait Disorders II-42

St.Jude Medical Launches Penta Surgical Leads in Japan II-42

Neurotech® Introduces Kneehab® XP Quadriceps Therapy System II-42

St.Jude Medical Launches Epiducer Lead Delivery System in

Australia II-43

Neurowave Medical Technologies™ Unveils Reletex™

Neuromodulation Device II-43

ST Jude Medical Rolls out Genesis Neurostimulation System in

Japan II-43

Medtronic Unveils Brain Stimulation Products II-44

Alphalife Launches Alpha Brainwave Neurostimulator II-44

ImThera Medical Introduces aura6000™ Neurostimulation System II-44

Mobilis Healthcare Introduces InterX II-44

IMEC Develops and Models New Design for Brain Stimulation

Implants II-45

11. FOCUS ON SELECT PLAYERS II-46Bioness Inc. (USA) II-46Boston Scientific Corp. (USA) II-46Cyberonics, Inc. (USA) II-46Medtronic, Inc. (USA) II-47St. Jude Medical, Inc. (USA) II-47Synapse Biomedical, Inc. (USA) II-48SPR Therapeutics, LLC (US) II-48

12. GLOBAL MARKET PERSPECTIVE II-49

Table 4: World Recent Past, Current & Future Analysis for

Neurostimulation by Geographic Region - US and Rest of World

Markets Independently Analyzed with Annual Sales Figures in

US$ Million for the Years 2010 through 2018 (includes

corresponding Graph/Chart) II-49

Table 5: World Historic Review for Neurostimulation byGeographic Region - US and Rest of World Markets IndependentlyAnalyzed with Annual Sales Figures in US$ Million for theYears 2004 through 2009 (includes corresponding Graph/Chart) II-50

Table 6: World 15-Year Perspective for Neurostimulation by

Geographic Region - Percentage Breakdown of Value Sales for US

and Rest of World Markets for the Years 2004, 2011 and 2018

(includes corresponding Graph/Chart) II-51

Table 7: World Recent Past, Current & Future Analysis forSpinal Cord Stimulators by Geographic Region - US and Rest ofWorld Markets Independently Analyzed with Annual Sales Figuresin US$ Million for the Years 2010 through 2018 (includescorresponding Graph/Chart) II-52

Table 8: World Recent Past, Current & Future Analysis for

Spinal Cord Stimulators by Product Segment - Radio Frequency

(RF) System and Implantable Pulse Generator (IPG) Markets

Independently Analyzed with Annual Sales Figures in US$

Million for the Years 2010 through 2018 (includes

corresponding Graph/Chart) II-53

Table 9: World Historic Review for Spinal Cord Stimulators byGeographic Region - US and Rest of World MarketsIndependently Analyzed with Annual Sales Figures in US$Million for the Years 2004 through 2009 (includescorresponding Graph/Chart) II-54

Table 10: World Historic Review for Spinal Cord Stimulators

by Product Segment - Radio Frequency (RF) System and

Implantable Pulse Generator (IPG) Markets Independently

Analyzed with Annual Sales Figures in US$ Million for the

Years 2004 through 2009 (includes corresponding Graph/Chart) II-55

Table 11: World 15-Year Perspective for Spinal CordStimulators by Geographic Region - Percentage Breakdown ofValue Sales for United States and Rest of the World Marketsfor the Years 2004, 2011 and 2018 (includes correspondingGraph/Chart) II-56

Table 12: World 15-Year Perspective for Spinal Cord

Stimulators by Product Segment - Percentage Breakdown of Value

Sales for Radio Frequency (RF) System and Implantable Pulse

Generator (IPG) Markets for the Years 2004, 2011 and 2018

(includes corresponding Graph/Chart) II-57

Table 13: World Recent Past, Current & Future Analysis forRadio Frequency Spinal Cord Stimulators by Geographic Region -US and Rest of World Markets Independently Analyzed withAnnual Sales Figures in US$ Million for the Years 2010 through2018 (includes corresponding Graph/Chart) II-58

Table 14: World Historic Review for Radio Frequency Spinal

Cord Stimulators by Geographic Region - US and Rest of World

Markets Independently Analyzed with Annual Sales Figures in

US$ Million for the Years 2004 through 2009 (includes

corresponding Graph/Chart) II-59

Table 15: World 15-Year Perspective for Radio FrequencySpinal Cord Stimulators by Geographic Region - PercentageBreakdown of Value Sales for United States and Rest of theWorld Markets for the Years 2004, 2011 and 2018 (includescorresponding Graph/Chart) II-60

Table 16: World Recent Past, Current & Future Analysis for

Implantable Pulse Generator (IPG) Spinal Cord Stimulators by

Geographic Region - US and Rest of World Markets

Independently Analyzed with Annual Sales Figures in US$

Million for the Years 2010 through 2018 (includes

corresponding Graph/Chart) II-61

Table 17: World Historic Review for Implantable PulseGenerator (IPG) Spinal Cord Stimulators by Geographic Region -US and Rest of World Markets Independently Analyzed withAnnual Sales Figures in US$ Million for the Years 2004through 2009 (includes corresponding Graph/Chart) II-62

Table 18: World 15-Year Perspective for Implantable Pulse

Generator (IPG) Spinal Cord Stimulators by Geographic Region -

Percentage Breakdown of Value Sales for US and Rest of World

Markets for the Years 2004, 2011 and 2018 (includes

corresponding Graph/Chart) II-63

Table 19: World Recent Past, Current & Future Analysis forDeep Brain Stimulators by Geographic Region - US and Rest ofWorld Markets Independently Analyzed with Annual Sales Figuresin US$ Million for the Years 2010 through 2018 (includescorresponding Graph/Chart) II-64

Table 20: World Historic Review for Deep Brain Stimulators by

Geographic Region - US and Rest of World Markets Independently

Analyzed with Annual Sales Figures in US$ Million for the

Years 2004 through 2009 (includes corresponding Graph/Chart) II-65

Table 21: World 15-Year Perspective for Deep Brain Stimulatorsby Geographic Region - Percentage Breakdown of Value Sales forUnited States and Rest of the World Markets for the Years2004, 2011 and 2018 (includes corresponding Graph/Chart) II-66

Table 22: World Recent Past, Current & Future Analysis for

Sacral Nerve Stimulators by Geographic Region - US and Rest of

World Markets Independently Analyzed with Annual Sales Figures

in US$ Million for the Years 2010 through 2018 (includes

corresponding Graph/Chart) II-67

Table 23: World Historic Review for Sacral Nerve Stimulatorsby Geographic Region - US and Rest of World MarketsIndependently Analyzed with Annual Sales Figures in US$Million for the Years 2004 through 2009 (includescorresponding Graph/Chart) II-68

Table 24: World 15-Year Perspective for Sacral Nerve

Stimulators by Geographic Region - Percentage Breakdown of

Value Sales for United States and Rest of the World Markets

for the Years 2004, 2011 and 2018 (includes corresponding

Graph/Chart) II-69

Table 25: World Recent Past, Current & Future Analysis forVagus Nerve Stimulators by Geographic Region - US and Rest ofWorld Markets Independently Analyzed with Annual Sales Figuresin US$ Million for the Years 2010 through 2018 (includescorresponding Graph/Chart) II-70

Table 26: World Historic Review for Vagus Nerve Stimulators by

Geographic Region - US and Rest of World Markets

Independently Analyzed with Annual Sales Figures in US$

Million for the Years 2004 through 2009 (includes

corresponding Graph/Chart) II-71

Table 27: World 15-Year Perspective for Vagus NerveStimulators by Geographic Region - Percentage Breakdown ofValue Sales for United States and Rest of the World Marketsfor the Years 2004, 2011 and 2018 (includes correspondingGraph/Chart) II-72III. MARKET

1. THE UNITED STATES III-1

A.Market Analysis III-1

Overview III-1

Neurostimulation Products Market to Witness Growth III-1

Product Segments Ranked by Growth III-2

Table 28: Neurostimulation Market in the US (2010-2018):

Product Segments Ranked by Growth (Sales in US$

million)(includes corresponding Graph/Chart) III-2

Table 29: Neurostimulation Market in the US (2010-2018):Product Segments Ranked by Growth (Sales in Units)(includes corresponding Graph/Chart) III-3

Table 30: Neurostimulation Market in the US (2011): Unit

Sales & Percentage Breakdown by Product Segment - Spinal

Cord Stimulators (SCS), Deep Brain Stimulators (DBS),

Sacral Nerve Stimulators (SNS), Vagus Nerve Stimulators

(VNS) and Gastric Electric Stimulators (GES) (includes

corresponding Graph/Chart) III-3

Table 31: Neurostimulation Market in the US (2011): ValueSales (in US$ Million) & Percentage Market Share byProduct Segment - Spinal Cord Stimulators (SCS), DeepBrain Stimulators (DBS), Sacral Nerve Stimulators (SNS),Vagus Nerve Stimulators (VNS) and Gastric ElectricStimulators (GES) (includes corresponding Graph/Chart) III-4Potential Growth for Neurostimulation Systems in the US III-4Spinal Cord Stimulation Products Market III-5Table 32: US Spinal Cord Stimulator Market (2011):Percentage Share Breakdown by Company - Medtronic,St.Jude Medical Boston Scientific (includes correspondingGraph/Chart) III-5Sacral Nerve Stimulation Products Market III-5Deep Brain Stimulation Products Market III-6Shift Away from Orthopaedic and Cardiovascular Device Markets III-6Trends in the Embolotherapy Market III-7Neurovascular Stents Market Attracting Cardiovascular Companies III-8Migraine Devices - New Frontiers for Neurostimulation III-8Competitive Landscape III-8Table 33: Leading Players in the US NeurostimulationMarket (2011): Percentage Breakdown of Revenues forMedtronic, Advanced Bionics, St. Jude Medical, Cyberonicsand Others (includes corresponding Graph/Chart) III-9Neurostimulation Device Approvals III-9Recent Industry Activity III-13Product Innovations/ Introductions III-17Key Players III-19B.Market Analytics III-22Table 34: US Recent Past, Current & Future Analysis forNeurostimulators by Product Segment - Spinal CordStimulators (SCS), Deep Brain Stimulators (DBS), SacralNerve Stimulators (SNS), Vagus Nerve Stimulators (VNS), andGastric Electric Stimulators (GES) Markets IndependentlyAnalyzed with Annual Sales Figures in Units for Years 2010through 2018 (includes corresponding Graph/Chart) III-22

Table 35: US Recent Past, Current & Future Analysis for

Neurostimulators by Product Segment - Spinal Cord

Stimulators (SCS), Deep Brain Stimulators (DBS), Sacral

Nerve Stimulators (SNS), Vagus Nerve Stimulators (VNS), and

Gastric Electric Stimulators (GES) Markets Independently

Analyzed with Annual Sales Figures in US$ Million for Years

2010 through 2018 (includes corresponding Graph/Chart) III-23

Table 36: US Historic Review for Neurostimulators by ProductSegment - Spinal Cord Stimulators (SCS), Deep BrainStimulators (DBS), Sacral Nerve Stimulators (SNS), VagusNerve Stimulators (VNS), and Gastric Electric Stimulators(GES) Markets Independently Analyzed with Annual SalesFigures in Units for Years 2004 through 2009 (includescorresponding Graph/Chart) III-24

Table 37: US Historic Review for Neurostimulators by Product

Segment - Spinal Cord Stimulators (SCS), Deep Brain

Stimulators (DBS), Sacral Nerve Stimulators (SNS), Vagus

Nerve Stimulators (VNS), and Gastric Electric Stimulators

(GES) Markets Independently Analyzed with Annual Sales

Figures in US$ Million for Years 2004 through 2009 (includes

corresponding Graph/Chart) III-25

Table 38: US 15-Year Perspective for Neurostimulators byProduct Segment - Percentage Breakdown of Unit Sales forSpinal Cord Stimulators (SCS), Deep Brain Stimulators (DBS),Sacral Nerve Stimulators (SNS), Vagus Nerve Stimulators(VNS), and Gastric Electric Stimulators (GES) Markets forthe Years 2004, 2011 and 2018 (includes correspondingGraph/Chart) III-26

Table 39: US 15-Year Perspective for Neurostimulators by

Product Segment - Percentage Breakdown of Value Sales for

Spinal Cord Stimulators (SCS), Deep Brain Stimulators

(DBS), Sacral Nerve Stimulators (SNS), Vagus Nerve

Stimulators (VNS), and Gastric Electric Stimulators (GES)

Markets for the Years 2004, 2011 and 2018 (includes

corresponding Graph/Chart) III-27

Table 40: US Recent Past, Current & Future Analysis forSpinal Cord Stimulators by Product Segment - Radio Frequency(RF) System and Implantable Pulse Generator (IPG) MarketsIndependently Analyzed with Annual Sales Figures in Unitsfor Years 2010 through 2018 (includes correspondingGraph/Chart) III-28

Table 41: US Recent Past, Current & Future Analysis for

Spinal Cord Stimulators by Product Segment - Radio Frequency

(RF) System and Implantable Pulse Generator (IPG) Markets

Independently Analyzed with Annual Sales Figures in US$

Million for Years 2010 through 2018 (includes corresponding

Graph/Chart) III-29

Table 42: US Historic Review for Spinal Cord Stimulators byProduct Segment - Radio Frequency (RF) System andImplantable Pulse Generator (IPG) Markets IndependentlyAnalyzed with Annual Sales Figures in Units for Years 2004through 2009 (includes corresponding Graph/Chart) III-30

Table 43: US Historic Review for Spinal Cord Stimulators by

Product Segment - Radio Frequency (RF) System and

Implantable Pulse Generator (IPG) Markets Independently

Analyzed with Annual Sales Figures in US$ Million for Years

2004 through 2009 (includes corresponding Graph/Chart) III-31

Table 44: US 15-Year Perspective for Spinal Cord Stimulatorsby Product Segment - Percentage Breakdown of Unit Sales forRadio Frequency (RF) System and Implantable Pulse Generator(IPG) Markets for the Years 2004, 2011 and 2018 (includescorresponding Graph/Chart) III-32

Table 45: US 15-Year Perspective for Spinal Cord Stimulators

by Product Segment - Percentage Breakdown of Value Sales for

Radio Frequency (RF) System and Implantable Pulse Generator

(IPG) Markets for the Years 2004, 2011 and 2018 (includes

corresponding Graph/Chart) III-33

2. REST OF WORLD III-34A.Market Analysis III-34Outlook III-34Neurostimulation Device Approvals III-34Recent Industry Activity III-38Product Innovations/ Introductions III-38B.Market Analytics III-40Table 46: Rest of World Recent Past, Current & FutureAnalysis for Neurostimulators by Product Segment - SpinalCord Stimulators (SCS), Deep Brain Stimulators (DBS),Sacral Nerve Stimulators (SNS), Vagus Nerve Stimulators(VNS), and Gastric Electric Stimulators (GES) MarketsIndependently Analyzed with Annual Sales Figures in US$Million for Years 2010 through 2018 (includes correspondingGraph/Chart) III-40

Table 47: Rest of World Historic Review for

Neurostimulators by Product Segment - Spinal Cord

Stimulators (SCS), Deep Brain Stimulators (DBS), Sacral

Nerve Stimulators (SNS), Vagus Nerve Stimulators (VNS), and

Gastric Electric Stimulators (GES) Markets Independently

Analyzed with Annual Sales Figures in US$ Million for Years

2004 through 2009 (includes corresponding Graph/Chart) III-41

Table 48: Rest of World 15-Year Perspective forNeurostimulators by Product Segment - Percentage Breakdownof Value Sales for Spinal Cord Stimulators (SCS), DeepBrain Stimulators (DBS), Sacral Nerve Stimulators (SNS),Vagus Nerve Stimulators (VNS), and Gastric ElectricStimulators (GES) Markets for the Years 2004, 2011 and 2018(includes corresponding Graph/Chart) III-42

Table 49: Rest of World Recent Past, Current & Future

Analysis for Spinal Cord Stimulators by Product Segment -

Radio Frequency (RF) System and Implantable Pulse Generator

(IPG) Markets Independently Analyzed with Annual Sales

Figures in US$ Million for Years 2010 through 2018

(includes corresponding Graph/Chart) III-43

Table 50: Rest of World Historic Review for Spinal CordStimulators by Product Segment - Radio Frequency (RF) Systemand Implantable Pulse Generator (IPG) Markets IndependentlyAnalyzed with Annual Sales Figures in US$ Million for Years2004 through 2009 (includes corresponding Graph/Chart) III-44

Table 51: Rest of World 15-Year Perspective for Spinal Cord

Stimulators by Product Segment - Percentage Breakdown of

Value Sales for Radio Frequency (RF) System and Implantable

Pulse Generator (IPG) Markets for the Years 2004, 2011 and

2018 (includes corresponding Graph/Chart) III-45

IV. COMPETITIVE LANDSCAPE

Total Companies Profiled: 21 (including Divisions/Subsidiaries - 24)

The United States (16)Canada (1)Europe (5)- The United Kingdom (2)- Rest of Europe (3)Asia-Pacific (Excluding Japan) (1)Middle-East (1)

To order this report:Medical_Equipment_and_Supply Industry: Global Neurostimulation Industry

Nicolas Bombourg

Reportlinker

Email: [email protected]

US: (805)652-2626

Intl: +1 805-652-2626

SOURCE Reportlinker

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