|By PR Newswire||
|January 16, 2013 05:33 PM EST||
LONDON, Jan. 16, 2013 /PRNewswire/ -- Bioradar UK Ltd this week reported that the H3N2 Lethality Gene Counts are approaching those of the highly lethal H3N2 pandemic of 1968 (1)(see Figure).
The severe flu outbreaks in 41 U.S. states in the first week of 2013 (CDC), predominately H3N2, further suggest that the State Fair 2012 H3N2 cases and the current outbreaks may be the opening salvos of an approaching H3N2 pandemic.
Bioradar UK Ltd reported in November 2012 that the Replikin Counts of the Replikins Infectivity Gene of H3N2 was rising. Between 2009 and 2011, the rising Count preceded the State Fair Swine Flu H3N2 Outbreak in children and pigs in the U.S. in 2012 (2).
The same Replikin technology measuring genomic H1N1 in Mexico in 2008 also correctly predicted the 2009 H1N1 Pandemic, one year before its emergence, and predicted the recent outbreaks of H5N1 in Cambodia, two years in advance (3-6).
In the present study of H3N2, 8,269 replikins lethality gene sequences were analyzed from 1968 to 2012. Virus "resting periods" with low levels of replication are correlated with Counts equal to and below 4.0 Replikins per 100 genomic amino acids; rising Counts above 4.0 to date invariably precede and predict major outbreaks and pandemics (p<0.001). All instances of statistically significant (p<0.001) increases or decreases in Replikin®Counts have correlated with outbreaks or clinical decreases respectively.
There have been no "false positives" or "false negatives" (2-5) in the replikin predictions: H1N1 (2008 prediction for the 2009 pandemic, 2010 for the 2010 outbreak, 2011 for 2012 outbreak); H5N1 (1996 for 1997, 2005 for 2006-07, 2009 for 2011 outbreak); three influenza pandemics of the past century- H1N1, H2N2, H3N2; SARS (2003 for 2004); Foot and Mouth Disease (2010 for 2011-12); E. Coli (2005-2010 for 2011); and malaria (for 1998-2006 decrease in mortality).
Because nine of nine trials indicate that a rising Replikin®Count is accurately predictive of specific strain outbreaks and their location, Bioradar UK Ltd has proposed the possibility of preventing or ameliorating the next flu pandemic (5). The risks of human as well as animal mortality are now predictable. The specific Replikin chemistry of the emerging pathogen's genome is now predictable. More time is now available, as early as one to two years in advance, to organize public health responses and to produce, to adequately test and to distribute vaccines and therapeutic agents well in advance of an outbreak.
The geographic site of an outbreak is also now predictable by Replikin Count, as shown by Bioradar in Mexico, Indonesia, Cambodia, and now in the U.S. (2-6). Production, testing and distribution of vaccine prior to the development of outbreaks and further escalation to pandemics in their local geographic site is now possible.
1. Ce'cile Viboud, et al , for the Multinational Inﬂuenza Seasonal Mortality Study Group.
The Journal of Infectious Diseases 2005; 192:233–48
2. Report #52 <Replikins.com>website, 2006-2013.
3. Bogoch, S. and Bogoch, E.S. Genome Replikin Count™ Predicts Increased Infectivity/Lethality of Viruses. Nature Precedings npre20127144. O4April 2012.
4. Bogoch, S. and Bogoch, E.S. Prediction of specific virus outbreaks made from the increased concentration of a new class of virus genomic peptides, replikins. Nature Precedings doi:10.1038/npre.2011.6279.1.23Aug 2011.
5. Bogoch,S. and Bogoch, ES. Bogoch Replikins Pandemic Prevention: Increase of Strain-Specific Influenza Genomic Replikin Counts, Having Predicted Outbreaks and their Location Seven Times Consecutively, Up to Two Years in Advance, Provides Time for Prevention of Pandemics. Nature Precedings.doi:10.1038/npre.2012.6952.1 01 March, 2012
6. UN Food and Agriculture Organization (FAO) discussion of Replikins, DVM Newsmagazine, (Sept. 8, 2011). Reproduced in Report #42 , Replikins.com
This press release was issued through eReleases® Press Release Distribution. For more information, visit http://www.ereleases.com.
The IoT is changing the way enterprises conduct business. In his session at @ThingsExpo, Eric Hoffman, Vice President at EastBanc Technologies, discussed how businesses can gain an edge over competitors by empowering consumers to take control through IoT. He cited examples such as a Washington, D.C.-based sports club that leveraged IoT and the cloud to develop a comprehensive booking system. He also highlighted how IoT can revitalize and restore outdated business models, making them profitable ...
Jul. 25, 2016 08:30 PM EDT Reads: 1,923
StackIQ has announced the release of Stacki 3.2. Stacki is an easy-to-use Linux server provisioning tool. Stacki 3.2 delivers new capabilities that simplify the automation and integration of site-specific requirements. StackIQ is the commercial entity behind this open source bare metal provisioning tool. Since the release of Stacki in June of 2015, the Stacki core team has been focused on making the Community Edition meet the needs of members of the community, adding features and value, while ...
Jul. 25, 2016 08:15 PM EDT Reads: 206
The cloud competition for database hosts is fierce. How do you evaluate a cloud provider for your database platform? In his session at 18th Cloud Expo, Chris Presley, a Solutions Architect at Pythian, gave users a checklist of considerations when choosing a provider. Chris Presley is a Solutions Architect at Pythian. He loves order – making him a premier Microsoft SQL Server expert. Not only has he programmed and administered SQL Server, but he has also shared his expertise and passion with b...
Jul. 25, 2016 08:00 PM EDT Reads: 1,892
With 15% of enterprises adopting a hybrid IT strategy, you need to set a plan to integrate hybrid cloud throughout your infrastructure. In his session at 18th Cloud Expo, Steven Dreher, Director of Solutions Architecture at Green House Data, discussed how to plan for shifting resource requirements, overcome challenges, and implement hybrid IT alongside your existing data center assets. Highlights included anticipating workload, cost and resource calculations, integrating services on both sides...
Jul. 25, 2016 08:00 PM EDT Reads: 1,956
Big Data engines are powering a lot of service businesses right now. Data is collected from users from wearable technologies, web behaviors, purchase behavior as well as several arbitrary data points we’d never think of. The demand for faster and bigger engines to crunch and serve up the data to services is growing exponentially. You see a LOT of correlation between “Cloud” and “Big Data” but on Big Data and “Hybrid,” where hybrid hosting is the sanest approach to the Big Data Infrastructure pro...
Jul. 25, 2016 07:30 PM EDT Reads: 1,878
We all know the latest numbers: Gartner, Inc. forecasts that 6.4 billion connected things will be in use worldwide in 2016, up 30 percent from last year, and will reach 20.8 billion by 2020. We're rapidly approaching a data production of 40 zettabytes a day – more than we can every physically store, and exabytes and yottabytes are just around the corner. For many that’s a good sign, as data has been proven to equal money – IF it’s ingested, integrated, and analyzed fast enough. Without real-ti...
Jul. 25, 2016 07:15 PM EDT Reads: 986
In his session at 18th Cloud Expo, Sagi Brody, Chief Technology Officer at Webair Internet Development Inc., and Logan Best, Infrastructure & Network Engineer at Webair, focused on real world deployments of DDoS mitigation strategies in every layer of the network. He gave an overview of methods to prevent these attacks and best practices on how to provide protection in complex cloud platforms. He also outlined what we have found in our experience managing and running thousands of Linux and Unix ...
Jul. 25, 2016 07:15 PM EDT Reads: 1,742
In his session at @DevOpsSummit at 19th Cloud Expo, Yoseph Reuveni, Director of Software Engineering at Jet.com, will discuss Jet.com's journey into containerizing Microsoft-based technologies like C# and F# into Docker. He will talk about lessons learned and challenges faced, the Mono framework tryout and how they deployed everything into Azure cloud. Yoseph Reuveni is a technology leader with unique experience developing and running high throughput (over 1M tps) distributed systems with extre...
Jul. 25, 2016 07:15 PM EDT Reads: 2,080
"We are a well-established player in the application life cycle management market and we also have a very strong version control product," stated Flint Brenton, CEO of CollabNet,, in this SYS-CON.tv interview at 18th Cloud Expo, held June 7-9, 2016, at the Javits Center in New York City, NY.
Jul. 25, 2016 07:15 PM EDT Reads: 1,791
"Operations is sort of the maturation of cloud utilization and the move to the cloud," explained Steve Anderson, Product Manager for BMC’s Cloud Lifecycle Management, in this SYS-CON.tv interview at 18th Cloud Expo, held June 7-9, 2016, at the Javits Center in New York City, NY.
Jul. 25, 2016 07:00 PM EDT Reads: 1,878
I wanted to gather all of my Internet of Things (IOT) blogs into a single blog (that I could later use with my University of San Francisco (USF) Big Data “MBA” course). However as I started to pull these blogs together, I realized that my IOT discussion lacked a vision; it lacked an end point towards which an organization could drive their IOT envisioning, proof of value, app dev, data engineering and data science efforts. And I think that the IOT end point is really quite simple…
Jul. 25, 2016 06:30 PM EDT Reads: 962
UpGuard has become a member of the Center for Internet Security (CIS), and will continue to help businesses expand visibility into their cyber risk by providing hardening benchmarks to all customers. By incorporating these benchmarks, UpGuard's CSTAR solution builds on its lead in providing the most complete assessment of both internal and external cyber risk. CIS benchmarks are a widely accepted set of hardening guidelines that have been publicly available for years. Numerous solutions exist t...
Jul. 25, 2016 06:15 PM EDT Reads: 432
A critical component of any IoT project is what to do with all the data being generated. This data needs to be captured, processed, structured, and stored in a way to facilitate different kinds of queries. Traditional data warehouse and analytical systems are mature technologies that can be used to handle certain kinds of queries, but they are not always well suited to many problems, particularly when there is a need for real-time insights.
Jul. 25, 2016 06:15 PM EDT Reads: 1,742
We're entering the post-smartphone era, where wearable gadgets from watches and fitness bands to glasses and health aids will power the next technological revolution. With mass adoption of wearable devices comes a new data ecosystem that must be protected. Wearables open new pathways that facilitate the tracking, sharing and storing of consumers’ personal health, location and daily activity data. Consumers have some idea of the data these devices capture, but most don’t realize how revealing and...
Jul. 25, 2016 06:00 PM EDT Reads: 2,076
"Software-defined storage is a big problem in this industry because so many people have different definitions as they see fit to use it," stated Peter McCallum, VP of Datacenter Solutions at FalconStor Software, in this SYS-CON.tv interview at 18th Cloud Expo, held June 7-9, 2016, at the Javits Center in New York City, NY.
Jul. 25, 2016 06:00 PM EDT Reads: 1,422