Welcome!

News Feed Item

Brain Cancer Researcher Eric Holland, One Of The World's Top Neurosurgeons, To Join Fred Hutch And UW Medicine

He is recruited to establish a preeminent brain cancer program in Seattle

SEATTLE, April 1, 2013 /PRNewswire/ -- Eric Holland, M.D., Ph.D., an internationally renowned neurosurgeon and brain cancer researcher, has been recruited from Memorial Sloan-Kettering Cancer Center to Fred Hutchinson Cancer Research Center and the University of Washington to establish world-class research programs on brain and other solid-tumor cancers in Seattle. He will arrive this summer.

At Fred Hutch, where Holland's research laboratory will be based, he will be senior vice president and director of the Human Biology Division, an interdisciplinary program that encourages collaboration among faculty with a broad range of expertise – from molecular and cellular biology to genetics and clinical research. This unique structure fosters laboratory-based, computational and clinical research that yields discoveries which can be rapidly translated into treatments for cancer patients.

He will replace Denise Galloway, Ph.D., interim director and member of the Human Biology Division, who assumed that role in May 2011 upon the retirement of former division Director Barbara Trask, Ph.D.

"As a practicing neurosurgeon with an outstanding track record in molecular biology and genetics, Eric is at the forefront of translating laboratory advances into advanced molecular therapeutics – expertise that will be instrumental in catalyzing our efforts to build strength in clinical molecular diagnostics and precision oncology," said Larry Corey, M.D., president and director of Fred Hutch. "I am confident that Eric will help us apply the strategies he has developed and used so successfully for brain tumors to many other types of solid-tumor cancers. His recruitment will catalyze numerous opportunities of this kind for our institutions," he said.

With advances in genomics increasingly playing an important role in solid-tumor oncology, Holland's expertise will provide strong leadership in this area, strengthening Seattle's reputation in translational, solid-tumor research.

At Fred Hutch, Holland will oversee the recruitment of new laboratory-based investigators who are at the forefront of solid-tumor translational research in areas such as breast, prostate, gastrointestinal and other cancers.

At UW Medicine, Holland will be a professor of neurological surgery, hold the Chap and Eve Alvord and Elias Alvord Chair in Neuro-oncology and will direct the Nancy and Buster Alvord Brain Tumor Center. The Alvord Center was established in 2009 to promote, develop and coordinate outstanding interdisciplinary brain tumor care and research among physicians and scientists in a variety of fields ranging from neurology to radiation oncology.

As director of the Alvord Brain Tumor Center, one of Holland's first priorities will be to recruit a team of internationally renowned brain cancer investigators to implement the vision of the late Ellsworth "Buster" Alvord, a Seattle philanthropist and former head of the UW Department of Neuropathology. Alvord and his family funded five endowed chairs in five different UW Medicine departments to create a multidisciplinary research center to focus on brain cancer.

"Eric Holland is exceptionally well qualified to lead the Alvord Brain Tumor Center, and I am confident that he will recruit outstanding researchers and clinicians to establish the Alvord Center as the best in the world," said Paul G. Ramsey, M.D., CEO of UW Medicine and dean of the UW School of Medicine. "Under Dr. Holland's leadership, we will be able to fulfill the vision for brain cancer research and clinical care established by Buster Alvord when he and his family made their extraordinarily generous commitment to establish the Alvord Center. I am delighted to welcome Eric Holland to UW Medicine."

Holland said he is looking forward to the challenge of developing a world-class brain cancer and solid-tumor program in Seattle to build on the Hutchinson Center's pioneering, Nobel Prize-winning work in bone-marrow transplantation to treat leukemia and other blood cancers and to collaborate with the outstanding genome scientists at UW Medicine.

"I am thrilled at the prospect of working with the world's leading experts in genome sciences, computational biology and those involved in the development of novel platforms for delivering innovative therapies to cancer patients," Holland said. "The highly collaborative, multidisciplinary nature of cancer research at Fred Hutch and UW Medicine provides a solid foundation to build on."

Holland is currently the Emily Tow Jackson Chair in Oncology and the founding director of the Brain Tumor Center at Sloan-Kettering, where he has built one of the nation's most successful brain cancer research and clinical programs. He specializes in the research and treatment of glioma – the most common brain cancer in adults – and metastatic brain tumors. 

Throughout his career Holland has worked at the intersection of multiple disciplines to address the molecular basis of brain tumors and develop new approaches to their treatment. His research focuses on developing mouse models of brain cancer that mimic the behavior of the disease in patients. His work with mouse models has led to clinical trials in glioma patients. He also has developed imaging strategies to follow mouse brain tumors as they develop – a powerful system that is used to test promising new drugs with potential benefit for patients.

Among Holland's discoveries:

  • He was the first to use a system of postnatal gene transfer to study brain cancer formation in mice, providing a model for the development of gliomas and medulloblastomas.
  • His laboratory was the first to demonstrate that stem cells are more sensitive to changes that can lead to cancer, providing clues to cancer development and its ability to evade treatment.
  • He was the first to demonstrate that the activity of a protein called Akt is elevated in human glioblastomas – a finding that provided major insights into the development of this cancer.

Holland received his medical degree from Stanford University and his doctorate in molecular biology from the University of Chicago. His postdoctoral training included work with two Nobel laureates: Paul Berg, Ph.D., a pioneer of recombinant DNA technology at Stanford University; and Harold Varmus, M.D., director of the National Cancer Institute and former director of the National Institutes of Health. Prior to Holland's arrival at Sloan-Kettering in 2001 he conducted brain surgery and basic research at the University of Texas MD Anderson Cancer Center. He is a member of the National Academy of Sciences' prestigious Institute of Medicine.

About Fred Hutchinson Cancer Research Center
At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch's pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer with minimal side effects. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation's first and largest cancer prevention research program, as well as the clinical coordinating center of the Women's Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Private contributions are essential for enabling Fred Hutch scientists to explore novel research opportunities that lead to important medical breakthroughs. For more information visit www.fredhutch.org or follow Fred Hutch on Facebook, Twitter or YouTube.

About UW Medicine
UW Medicine includes: Harborview Medical Center, Northwest Hospital & Medical Center, Valley Medical Center, UW Medical Center, UW Neighborhood Clinics, UW Physicians, UW School of Medicine and Airlift Northwest. UW Medicine has major academic and service affiliations with Seattle Children's Hospital, Fred Hutchinson Cancer Research Center, the Veteran's Affairs Puget Sound Health Care System in Seattle, and the VA Hospital in Boise, Idaho. The UW School of Medicine is the top public institution for receipt of biomedical research funding from the National Institutes of Health (NIH) and second among all institutions for NIH funding, public and private.  UW Medicine's 2,000 full-time faculty and nearly 5,000 clinical faculty across its five-state WWAMI region (Washington, Wyoming, Alaska, Montana and Idaho) include three living Nobel Prize winners (five in its history), 32 members of the National Academy of Sciences, 35 members of the Institute of Medicine, and 13 Howard Hughes Medical Institute Investigators. For more information, visit UW Medicine. Follow us on Twitter – @UWMedicineNews

CONTACTS
Kristen Woodward – Fred Hutch
206-667-5095
[email protected]

Clare LaFond – UW Medicine
206-685-1323
[email protected]

SOURCE Fred Hutchinson Cancer Research Center

More Stories By PR Newswire

Copyright © 2007 PR Newswire. All rights reserved. Republication or redistribution of PRNewswire content is expressly prohibited without the prior written consent of PRNewswire. PRNewswire shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.

Latest Stories
Niagara Networks exhibited at the 19th International Cloud Expo, which took place at the Santa Clara Convention Center in Santa Clara, CA, in November 2016. Niagara Networks offers the highest port-density systems, and the most complete Next-Generation Network Visibility systems including Network Packet Brokers, Bypass Switches, and Network TAPs.
Web Real-Time Communication APIs have quickly revolutionized what browsers are capable of. In addition to video and audio streams, we can now bi-directionally send arbitrary data over WebRTC's PeerConnection Data Channels. With the advent of Progressive Web Apps and new hardware APIs such as WebBluetooh and WebUSB, we can finally enable users to stitch together the Internet of Things directly from their browsers while communicating privately and securely in a decentralized way.
Extreme Computing is the ability to leverage highly performant infrastructure and software to accelerate Big Data, machine learning, HPC, and Enterprise applications. High IOPS Storage, low-latency networks, in-memory databases, GPUs and other parallel accelerators are being used to achieve faster results and help businesses make better decisions. In his session at 18th Cloud Expo, Michael O'Neill, Strategic Business Development at NVIDIA, focused on some of the unique ways extreme computing is...
SYS-CON Events announced today that HTBase will exhibit at SYS-CON's 20th International Cloud Expo®, which will take place on June 6-8, 2017, at the Javits Center in New York City, NY. HTBase (Gartner 2016 Cool Vendor) delivers a Composable IT infrastructure solution architected for agility and increased efficiency. It turns compute, storage, and fabric into fluid pools of resources that are easily composed and re-composed to meet each application’s needs. With HTBase, companies can quickly prov...
SYS-CON Events announced today that Outlyer, a monitoring service for DevOps and operations teams, has been named “Bronze Sponsor” of SYS-CON's 20th International Cloud Expo®, which will take place on June 6-8, 2017, at the Javits Center in New York City, NY. Outlyer is a monitoring service for DevOps and Operations teams running Cloud, SaaS, Microservices and IoT deployments. Designed for today's dynamic environments that need beyond cloud-scale monitoring, we make monitoring effortless so you ...
SYS-CON Events announced today that MobiDev, a client-oriented software development company, will exhibit at SYS-CON's 20th International Cloud Expo®, which will take place June 6-8, 2017, at the Javits Center in New York City, NY, and the 21st International Cloud Expo®, which will take place October 31-November 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA. MobiDev is a software company that develops and delivers turn-key mobile apps, websites, web services, and complex softw...
What if you could build a web application that could support true web-scale traffic without having to ever provision or manage a single server? Sounds magical, and it is! In his session at 20th Cloud Expo, Chris Munns, Senior Developer Advocate for Serverless Applications at Amazon Web Services, will show how to build a serverless website that scales automatically using services like AWS Lambda, Amazon API Gateway, and Amazon S3. We will review several frameworks that can help you build serverle...
In his General Session at 17th Cloud Expo, Bruce Swann, Senior Product Marketing Manager for Adobe Campaign, explored the key ingredients of cross-channel marketing in a digital world. Learn how the Adobe Marketing Cloud can help marketers embrace opportunities for personalized, relevant and real-time customer engagement across offline (direct mail, point of sale, call center) and digital (email, website, SMS, mobile apps, social networks, connected objects).
SYS-CON Events announced today that Hitrons Solutions will exhibit at the 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. Hitrons Solutions Inc. is distributor in the North American market for unique products and services of small and medium-size businesses, including cloud services and solutions, SEO marketing platforms, and mobile applications.
With the introduction of IoT and Smart Living in every aspect of our lives, one question has become relevant: What are the security implications? To answer this, first we have to look and explore the security models of the technologies that IoT is founded upon. In his session at @ThingsExpo, Nevi Kaja, a Research Engineer at Ford Motor Company, will discuss some of the security challenges of the IoT infrastructure and relate how these aspects impact Smart Living. The material will be delivered i...
For organizations that have amassed large sums of software complexity, taking a microservices approach is the first step toward DevOps and continuous improvement / development. Integrating system-level analysis with microservices makes it easier to change and add functionality to applications at any time without the increase of risk. Before you start big transformation projects or a cloud migration, make sure these changes won’t take down your entire organization.
Historically, some banking activities such as trading have been relying heavily on analytics and cutting edge algorithmic tools. The coming of age of powerful data analytics solutions combined with the development of intelligent algorithms have created new opportunities for financial institutions. In his session at 20th Cloud Expo, Sebastien Meunier, Head of Digital for North America at Chappuis Halder & Co., will discuss how these tools can be leveraged to develop a lasting competitive advanta...
Your homes and cars can be automated and self-serviced. Why can't your storage? From simply asking questions to analyze and troubleshoot your infrastructure, to provisioning storage with snapshots, recovery and replication, your wildest sci-fi dream has come true. In his session at @DevOpsSummit at 20th Cloud Expo, Dan Florea, Director of Product Management at Tintri, will provide a ChatOps demo where you can talk to your storage and manage it from anywhere, through Slack and similar services ...
VeriStor Systems has announced that CRN has named VeriStor to its 2017 Managed Service Provider (MSP) 500 list in the Elite 150 category. This annual list recognizes North American solution providers with cutting-edge approaches to delivering managed services. Their offerings help companies navigate the complex and ever-changing landscape of IT, improve operational efficiencies, and maximize their return on IT investments. In today’s fast-paced business environments, MSPs play an important role...
SYS-CON Events announced today that CA Technologies has been named “Platinum Sponsor” of SYS-CON's 20th International Cloud Expo®, which will take place on June 6-8, 2017, at the Javits Center in New York City, NY, and the 21st International Cloud Expo®, which will take place October 31-November 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA. CA Technologies helps customers succeed in a future where every business – from apparel to energy – is being rewritten by software. From ...