Welcome!

News Feed Item

Elsevier Authors Peter HR Green and Benjamin Lebwohl offer Insights into Celiac Disease and the Risks of a Gluten-Free Diet

PHILADELPHIA, April 25, 2013 /PRNewswire/ -- In the last 50 years, the rates of Celiac Disease in the U.S. population increased four-fold, according to a 2009 Mayo Clinic study.  The reasons are still not clearly understood, but researchers believe that both genetic and environmental factors are behind the spike in cases.

With awareness of the disease has come an expansion of gluten-free products available on supermarket shelves and restaurant menus. However, a gluten-free diet is not a great idea for the general public, according to Peter H.R. Green, MD and Benjamin Lebwohl, MD, MS, co-editors of Celiac Disease, An Issue of Gastrointestinal Endoscopy Clinics  (Elsevier 2012).

"We've seen an increasing number of patients who say they feel better on a gluten-free diet, but don't appear to have the disease and we call this non-celiac gluten sensitivity. People who have symptoms should first be screened to rule out Celiac Disease before starting a gluten-free diet because once they start, all the parameters might improve, but they won't get an accurate diagnosis," says Dr. Green, director of the Celiac Disease Center at Columbia University and an attending physician at New York-Presbyterian Hospital.

He adds, "A gluten free diet is not necessarily a healthy diet. Non-wheat flour is not fortified the way wheat flour is, and this can lead to someone becoming B-vitamin and iron deficient. Also, some gluten-free foods have added sugar and fat to provide taste. However, a gluten-free diet can be a healthy diet if guided by an experienced dietitian."

Celiac Disease is an autoimmune condition triggered by dietary gluten. When a person with Celiac Disease eats gluten, the body sees it as a foreign enemy and begins to attack the gluten and the intestinal wall. This can result in damage to the bowel wall and the flattening of villi that help to maximize the absorption of nutrients. While weight loss and diarrhea are the most well-known side effects of Celiac Disease, epidemiologists now know that it can lead to anemia, peripheral neuropathy, and even infertility.

Only 20 percent of patients with Celiac Disease know they have it and the remaining 80 percent remain undiagnosed, often from improper screening, according to Dr. Lebwohl, Assistant Professor of Clinical Medicine and Epidemiology at Columbia University Medical Center. Many have adopted a gluten-free diet for a variety of reasons, including weight loss, a connection that has yet to be proven.

"We're very interested in better understanding risk factors for developing celiac disease," Dr. Lebwohl says. "Genes for celiac disease are found in 40% of all Americans and yet only 1% have symptoms of the disease.  We're studying populations to understand the environmental triggers and develop prevention strategies. There is some evidence, for example, that introducing gluten too early or too late in an infant's diet can increase the risk of developing celiac disease and that combining gluten introduction with breast feeding when an infant is between 4 to 6 months of age can be protective."

About Elsevier Authors
Elsevier is a world-leading publisher of scientific, technical and medical information products and services. A global business headquartered in Amsterdam, Elsevier (www.elsevier.com) works with thousands of physicians and researchers to publish multi-platform textbooks that shape medical practice around the world. Elsevier Authors are the leaders in their specialties, teaching and inspiring the next generation of health professionals. For a complete list of authors and expert commentary, visit www.ElsevierAuthors.com.

SOURCE Elsevier

More Stories By PR Newswire

Copyright © 2007 PR Newswire. All rights reserved. Republication or redistribution of PRNewswire content is expressly prohibited without the prior written consent of PRNewswire. PRNewswire shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.

Latest Stories
Whether they’re located in a public, private, or hybrid cloud environment, cloud technologies are constantly evolving. While the innovation is exciting, the end mission of delivering business value and rapidly producing incremental product features is paramount. In his session at @DevOpsSummit at 19th Cloud Expo, Kiran Chitturi, CTO Architect at Sungard AS, will discuss DevOps culture, its evolution of frameworks and technologies, and how it is achieving maturity. He will also cover various st...
Digital innovation is the next big wave of business transformation based on digital technologies of which IoT and Big Data are key components, For example: Business boundary innovation is a challenge to excavate third-party business value using IoT and BigData, like Nest Business structure innovation may propose re-building business structure from scratch, as Uber does in the taxicab industry The social model innovation is also a big challenge to the new social architecture with the design fr...
So, you bought into the current machine learning craze and went on to collect millions/billions of records from this promising new data source. Now, what do you do with them? Too often, the abundance of data quickly turns into an abundance of problems. How do you extract that "magic essence" from your data without falling into the common pitfalls? In her session at @ThingsExpo, Natalia Ponomareva, Software Engineer at Google, provided tips on how to be successful in large scale machine learning...
If you had a chance to enter on the ground level of the largest e-commerce market in the world – would you? China is the world’s most populated country with the second largest economy and the world’s fastest growing market. It is estimated that by 2018 the Chinese market will be reaching over $30 billion in gaming revenue alone. Admittedly for a foreign company, doing business in China can be challenging. Often changing laws, administrative regulations and the often inscrutable Chinese Interne...
Why do your mobile transformations need to happen today? Mobile is the strategy that enterprise transformation centers on to drive customer engagement. In his general session at @ThingsExpo, Roger Woods, Director, Mobile Product & Strategy – Adobe Marketing Cloud, covered key IoT and mobile trends that are forcing mobile transformation, key components of a solid mobile strategy and explored how brands are effectively driving mobile change throughout the enterprise.
In his session at @ThingsExpo, Kausik Sridharabalan, founder and CTO of Pulzze Systems, Inc., will focus on key challenges in building an Internet of Things solution infrastructure. He will shed light on efficient ways of defining interactions within IoT solutions, leading to cost and time reduction. He will also introduce ways to handle data and how one can develop IoT solutions that are lean, flexible and configurable, thus making IoT infrastructure agile and scalable.
Creating replica copies to tolerate a certain number of failures is easy, but very expensive at cloud-scale. Conventional RAID has lower overhead, but it is limited in the number of failures it can tolerate. And the management is like herding cats (overseeing capacity, rebuilds, migrations, and degraded performance). Download Slide Deck: ▸ Here In his general session at 18th Cloud Expo, Scott Cleland, Senior Director of Product Marketing for the HGST Cloud Infrastructure Business Unit, discusse...
Data is an unusual currency; it is not restricted by the same transactional limitations as money or people. In fact, the more that you leverage your data across multiple business use cases, the more valuable it becomes to the organization. And the same can be said about the organization’s analytics. In his session at 19th Cloud Expo, Bill Schmarzo, CTO for the Big Data Practice at EMC, will introduce a methodology for capturing, enriching and sharing data (and analytics) across the organizati...
SYS-CON Events announced today that Bsquare has been named “Silver Sponsor” of SYS-CON's @ThingsExpo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. For more than two decades, Bsquare has helped its customers extract business value from a broad array of physical assets by making them intelligent, connecting them, and using the data they generate to optimize business processes.
Internet of @ThingsExpo has announced today that Chris Matthieu has been named tech chair of Internet of @ThingsExpo 2016 Silicon Valley. The 6thInternet of @ThingsExpo will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA.
A strange thing is happening along the way to the Internet of Things, namely far too many devices to work with and manage. It has become clear that we'll need much higher efficiency user experiences that can allow us to more easily and scalably work with the thousands of devices that will soon be in each of our lives. Enter the conversational interface revolution, combining bots we can literally talk with, gesture to, and even direct with our thoughts, with embedded artificial intelligence, wh...
In his keynote at 18th Cloud Expo, Andrew Keys, Co-Founder of ConsenSys Enterprise, provided an overview of the evolution of the Internet and the Database and the future of their combination – the Blockchain. Andrew Keys is Co-Founder of ConsenSys Enterprise. He comes to ConsenSys Enterprise with capital markets, technology and entrepreneurial experience. Previously, he worked for UBS investment bank in equities analysis. Later, he was responsible for the creation and distribution of life sett...
Cloud computing is being adopted in one form or another by 94% of enterprises today. Tens of billions of new devices are being connected to The Internet of Things. And Big Data is driving this bus. An exponential increase is expected in the amount of information being processed, managed, analyzed, and acted upon by enterprise IT. This amazing is not part of some distant future - it is happening today. One report shows a 650% increase in enterprise data by 2020. Other estimates are even higher....
Video experiences should be unique and exciting! But that doesn’t mean you need to patch all the pieces yourself. Users demand rich and engaging experiences and new ways to connect with you. But creating robust video applications at scale can be complicated, time-consuming and expensive. In his session at @ThingsExpo, Zohar Babin, Vice President of Platform, Ecosystem and Community at Kaltura, will discuss how VPaaS enables you to move fast, creating scalable video experiences that reach your...
SYS-CON Events announced today that SoftLayer, an IBM Company, has been named “Gold Sponsor” of SYS-CON's 18th Cloud Expo, which will take place on June 7-9, 2016, at the Javits Center in New York, New York. SoftLayer, an IBM Company, provides cloud infrastructure as a service from a growing number of data centers and network points of presence around the world. SoftLayer’s customers range from Web startups to global enterprises.