|By PR Newswire||
|January 7, 2014 10:22 AM EST||
REHOVOT, Israel, January 7, 2014 /PRNewswire/ --
Advanced Inhalation Therapies (AIT Ltd.), an Israeli drug development company, announced today that it has begun enrollment in Israel for a multicenter, open label, Phase II clinical trial of NOxCureCF, a respiratory treatment for patients with cystic fibrosis (CF). NOxCureCF is a specialized formulation of inhaled Nitric Oxide (NO) delivered using AIT's patented drug delivery system.
David Greenberg, M.D., AIT's Chief Medical Officer and a professor of pediatrics and infectious diseases at Soroka Medical Center in Beersheva, Israel, said: "This study, in combination with the continuation of our Phase II trial of the use of NO for treatment of infants with RSV/bronchiolitis, will allow us to substantiate and enhance the use of inhaled NO in the treatment of respiratory disease and distress."
Prof. Asher Tal, head of the Pediatrics Department at Soroka University Medical Center, adds: "The NOxCureCF treatment may serve as a major improvement in the quality of life for CF patients, and may significally contribute to their life expectancy." The study takes place at Soroka's CF Clinic, which is led by Dr. Micha Aviram.
CF is a life-threatening genetic disease that causes the abnormal transport of salts across cells and most critically affects the lungs. CF patients are highly prone to opportunistic bacterial infections that often lead to prolonged, chronic lung infections, reducing life expectancy due to significant destruction of lung tissue. Approximately 70,000 individuals in Europe and North America suffer from CF, making it the most common life-threatening autosomal recessive disease.
The aim of the study is to assess the improvement in lung function after treatment with NOxCureCF in CF patients 10 years old and older. The study will also allow continuous testing of the safety and tolerability of the dosage and delivery system.
Prof Yossef Av Gay, AIT's CSO and a professor of microbiology at the University of British Columbia, Canada, states: "The ongoing studies, an outgrowth of the strategic alliance between Clalit Health Services and AIT, will strengthen the research and development in the critically important area of treatment of acute and chronic respiratory illness treatment with NO solutions."
About Nitric Oxide (NO)
Nitric Oxide (NO) is a small, naturally produced gas that acts as an anti-infection agent, making it very effective for the treatment of a wide range of diseases. AIT uses NO in unique dosages and in specialized delivery modes to enable direct, effective access to the lungs.
AIT (http://www.ait-pharm.com) is a drug development company focused on the development and commercialization of NO-based formulations for the treatment of respiratory or infectious diseases such as bronchiolitis, cystic fibrosis, pneumonia and asthma. NOxCureCF is one of a group of inhaled NO based therapeutics developed by AIT, for the treatment of infectious respiratory diseases such as Respiratory Syncytial Virus (RSV)/bronchiolitis, CF, pneumonia and asthma. The company successfully concluded Phase I trials and is currently conducting Phase II trials on RSV/bronchiolitis.
AIT was founded by Mor Research Applications, a subsidiary of Clalit Health Services, Israel's largest health management organization. The company is headquartered in Rehovot, Israel.
About Clalit Health Services
Clalit is the major health organization in Israel, and one of the most progressive public health associations in the world. Through its 14 hospitals and more than 1,400 primary and specialized clinics, Clalit provides comprehensive health insurance and highly advanced medical care to the majority of Israel's population. Clalit maintains a total of 14 general and special-care hospitals, all of which are affiliated with Israel's universities, a countrywide network of pharmacies, dental clinics, radiology facilities, as well as computerized diagnostic equipment at a number of central laboratories.
Clalit has 4 million insured members, a >52% market share, and managed an annual budget of more than $6 billion.
About Soroka University Medical Center
The Pediatric Division of the Soroka University Medical Center is one of the largest Pediatric Medical Center is Israel with 190 admission beds, 35,000 visits at the Pediatric ER, 14,500 admissions and 42,000 ambulatory visits. As the only tertiary medical center, which serves the diverse Negev Population, the medical team copes with unique medical conditions in children.
The medical team of 85 staff physicians and 270 nurses provides medical care to almost 300,000 children of the Negev population.
Racheli Vizman, COO, AIT
2 Derech Meir Weisgal
Rehovot 9632605, Israel
E-mail: [email protected]
SOURCE Advanced Inhalation Therapies (AIT)
In past @ThingsExpo presentations, Joseph di Paolantonio has explored how various Internet of Things (IoT) and data management and analytics (DMA) solution spaces will come together as sensor analytics ecosystems. This year, in his session at @ThingsExpo, Joseph di Paolantonio from DataArchon, will be adding the numerous Transportation areas, from autonomous vehicles to “Uber for containers.” While IoT data in any one area of Transportation will have a huge impact in that area, combining senso...
Oct. 21, 2016 07:15 PM EDT Reads: 212
Why do your mobile transformations need to happen today? Mobile is the strategy that enterprise transformation centers on to drive customer engagement. In his general session at @ThingsExpo, Roger Woods, Director, Mobile Product & Strategy – Adobe Marketing Cloud, covered key IoT and mobile trends that are forcing mobile transformation, key components of a solid mobile strategy and explored how brands are effectively driving mobile change throughout the enterprise.
Oct. 21, 2016 07:15 PM EDT Reads: 1,605
@ThingsExpo has been named the Top 5 Most Influential Internet of Things Brand by Onalytica in the ‘The Internet of Things Landscape 2015: Top 100 Individuals and Brands.' Onalytica analyzed Twitter conversations around the #IoT debate to uncover the most influential brands and individuals driving the conversation. Onalytica captured data from 56,224 users. The PageRank based methodology they use to extract influencers on a particular topic (tweets mentioning #InternetofThings or #IoT in this ...
Oct. 21, 2016 07:00 PM EDT Reads: 8,080
"Matrix is an ambitious open standard and implementation that's set up to break down the fragmentation problems that exist in IP messaging and VoIP communication," explained John Woolf, Technical Evangelist at Matrix, in this SYS-CON.tv interview at @ThingsExpo, held Nov 4–6, 2014, at the Santa Clara Convention Center in Santa Clara, CA.
Oct. 21, 2016 07:00 PM EDT Reads: 8,920
What are the new priorities for the connected business? First: businesses need to think differently about the types of connections they will need to make – these span well beyond the traditional app to app into more modern forms of integration including SaaS integrations, mobile integrations, APIs, device integration and Big Data integration. It’s important these are unified together vs. doing them all piecemeal. Second, these types of connections need to be simple to design, adapt and configure...
Oct. 21, 2016 06:45 PM EDT Reads: 1,852
The IoT has the potential to create a renaissance of manufacturing in the US and elsewhere. In his session at 18th Cloud Expo, Florent Solt, CTO and chief architect of Netvibes, discussed how the expected exponential increase in the amount of data that will be processed, transported, stored, and accessed means there will be a huge demand for smart technologies to deliver it. Florent Solt is the CTO and chief architect of Netvibes. Prior to joining Netvibes in 2007, he co-founded Rift Technologi...
Oct. 21, 2016 06:45 PM EDT Reads: 2,810
For basic one-to-one voice or video calling solutions, WebRTC has proven to be a very powerful technology. Although WebRTC’s core functionality is to provide secure, real-time p2p media streaming, leveraging native platform features and server-side components brings up new communication capabilities for web and native mobile applications, allowing for advanced multi-user use cases such as video broadcasting, conferencing, and media recording.
Oct. 21, 2016 06:15 PM EDT Reads: 3,004
Kubernetes, Docker and containers are changing the world, and how companies are deploying their software and running their infrastructure. With the shift in how applications are built and deployed, new challenges must be solved. In his session at @DevOpsSummit at19th Cloud Expo, Sebastian Scheele, co-founder of Loodse, will discuss the implications of containerized applications/infrastructures and their impact on the enterprise. In a real world example based on Kubernetes, he will show how to ...
Oct. 21, 2016 05:15 PM EDT Reads: 2,812
Without lifecycle traceability and visibility across the tool chain, stakeholders from Planning-to-Ops have limited insight and answers to who, what, when, why and how across the DevOps lifecycle. This impacts the ability to deliver high quality software at the needed velocity to drive positive business outcomes. In his general session at @DevOpsSummit at 19th Cloud Expo, Eric Robertson, General Manager at CollabNet, will discuss how customers are able to achieve a level of transparency that e...
Oct. 21, 2016 05:15 PM EDT Reads: 597
@DevOpsSummit has been named the ‘Top DevOps Influencer' by iTrend. iTrend processes millions of conversations, tweets, interactions, news articles, press releases, blog posts - and extract meaning form them and analyzes mobile and desktop software platforms used to communicate, various metadata (such as geo location), and automation tools. In overall placement, @DevOpsSummit ranked as the number one ‘DevOps Influencer' followed by @CloudExpo at third, and @MicroservicesE at 24th.
Oct. 21, 2016 04:30 PM EDT Reads: 3,789
24Notion is full-service global creative digital marketing, technology and lifestyle agency that combines strategic ideas with customized tactical execution. With a broad understand of the art of traditional marketing, new media, communications and social influence, 24Notion uniquely understands how to connect your brand strategy with the right consumer. 24Notion ranked #12 on Corporate Social Responsibility - Book of List.
Oct. 21, 2016 04:15 PM EDT Reads: 1,481
Established in 1998, Calsoft is a leading software product engineering Services Company specializing in Storage, Networking, Virtualization and Cloud business verticals. Calsoft provides End-to-End Product Development, Quality Assurance Sustenance, Solution Engineering and Professional Services expertise to assist customers in achieving their product development and business goals. The company's deep domain knowledge of Storage, Virtualization, Networking and Cloud verticals helps in delivering ...
Oct. 21, 2016 04:15 PM EDT Reads: 915
Most of us already know that adopting new cloud applications can boost a business’s productivity by enabling organizations to be more agile and ready to change course in our fast-moving and connected digital world. But the rapid adoption of cloud apps and services also brings with it profound security threats, including visibility and control challenges that aren’t present in traditional on-premises environments. At the same time, the cloud – because of its interconnected, flexible and adaptable...
Oct. 21, 2016 04:00 PM EDT Reads: 2,687
In his session at @DevOpsSummit at 19th Cloud Expo, Robert Doyle, lead architect at eCube Systems, will examine the issues and need for an agile infrastructure and show the advantages of capturing developer knowledge in an exportable file for migration into production. He will introduce the use of NXTmonitor, a next-generation DevOps tool that captures application environments, dependencies and start/stop procedures in a portable configuration file with an easy-to-use GUI. In addition to captu...
Oct. 21, 2016 04:00 PM EDT Reads: 1,467
SYS-CON Events announced today that SoftNet Solutions will exhibit at the 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. SoftNet Solutions specializes in Enterprise Solutions for Hadoop and Big Data. It offers customers the most open, robust, and value-conscious portfolio of solutions, services, and tools for the shortest route to success with Big Data. The unique differentiator is the ability to architect and...
Oct. 21, 2016 03:54 PM EDT Reads: 282