|By PR Newswire||
|January 9, 2014 03:02 AM EST||
PARIS, January 9, 2014 /PRNewswire/ --
Innovative adhesive technology published as a cover feature in the high impact journal, Science Translational Medicine
Gecko Biomedical, a French medical device company developing 'bio-inspired' biodegradable surgical glues and patches for wound closure, announces that the Company's co-founders have published data demonstrating the potential of its paradigm-shifting technologies for minimally invasive reconstructive heart surgery.
'Bio-inspired' biodegradable surgical glue repairs defects of the heart and blood vessels
In a paper entitled "A Blood-Resistant Surgical Glue for Minimally Invasive Repair of Vessels and Heart Defects", published in the January 8, 2014 issue of Science Translational Medicine (online) (Ref. 1), the authors, including Gecko Biomedical co-founders Robert Langer Sc.D. (Massachusetts Institute of Technology) and Jeffrey Karp Ph.D. (Brigham and Women's Hospital), describe a revolutionary biodegradable and biocompatible surgical glue that was inspired by adhesive mechanisms observed in nature that function in challenging yet comparable (wet and dynamic) environments to those found in the body.
The 'bio-inspired' glue described is non-toxic, binds strongly to tissues offering a leak-proof seal on demand, and works well in the presence of actively contracting tissues and blood flow. The authors demonstrate how the adhesive, alone or in conjunction with a biodegradable patch, can effectively be used to repair defects (ruptures) of the heart and blood vessels during minimally invasive procedures.
Precise control of the wound closure process could shift the surgical paradigm
The glue is based on the combination of safe, naturally occurring compounds to form a biocompatible pre-polymer with tunable adhesive and mechanical properties. The glue is soft and elastic when applied to the wet surfaces of the wounds where it adheres gently to the tissues, permitting fine adjustments or repositioning when used with the patch. The glue is activated (polymerized) upon exposure to ultraviolet (UV) light to form a strong, leak-proof but flexible seal, giving the surgeon full control of the process. The adhesive can be engineered with mechanical characteristics similar to arteries and the digestive system, where initial applications are targeted. The authors also describe how the composition of the pre-polymer can be adjusted for strength or rate of biodegradation to suit the wound being repaired.
Jeffrey Karp, from the Department of Medicine at the Brigham and Women's Hospital, a co-founder of Gecko Biomedical and co-senior author of the study, said: "The tissue adhesive that we developed satisfies a long list of design criteria including biodegradation, biocompatibility, ability to strongly adhere on-demand to tissue with a water-tight seal in the presence of flowing blood, and elastic properties to accommodate cyclical forces such as those exerted by a beating heart or blood vessel. It offers the potential to reduce the invasiveness of surgical procedures, reduce operative times, and improve outcomes for patients."
"This platform of adhesive elastomers is truly versatile to address multiple meaningful applications in the clinic," said Maria N. Pereira, Ph.D., co-first author of the study who was previously in the Department of Medicine at the Brigham and Women's Hospital and is now Head of Adhesive Technologies at Gecko Biomedical.
Christophe Bancel, Chief Executive Officer of Gecko Biomedical, added: "The science and research supporting the development of Gecko's liquid film adhesive and patch technologies is of the highest quality. What has been achieved so far is very exciting and we are focused on undertaking the further necessary steps to get these innovative products into the hands of surgeons within the next few years, for the benefit of patients."
Reference: Lang, N. et al (2014) "A Blood-Resistant Surgical Glue for Minimally Invasive Repair of Vessels and Heart Defects," Sci. Transl. Med. 6, 218ra6 (2014)
Notes to Editors
About Gecko Biomedical
Gecko Biomedical is a privately owned medical device company based in Paris, France that is dedicated to the rapid development and the commercialization of revolutionary biodegradable sealants and adhesives for wound closure in the field of surgery, with a key focus on minimally invasive surgery. Gecko Biomedical is developing products that are non-toxic, bind strongly to tissues and deliver 'on-demand' wound closure within the 'wet' and dynamic environments in the body. The Company's technology and products are based on world-class research and intellectual property from the laboratories of Robert Langer (MIT) and Jeff Karp (Brigham and Women's Hospital). Gecko was founded in 2013 and is backed by leading healthcare investors Omnes Capital, CM-CIC and CapDecisif Management.
Further information: http://www.geckobiomedical.com or @geckobiomedical or http://www.linkedlinkedin.com/company/gecko-biomedical
SYS-CON Events announced today that Hitrons Solutions will exhibit at the 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. Hitrons Solutions Inc. is distributor in the North American market for unique products and services of small and medium-size businesses, including cloud services and solutions, SEO marketing platforms, and mobile applications.
Feb. 26, 2017 07:00 AM EST
In an era of historic innovation fueled by unprecedented access to data and technology, the low cost and risk of entering new markets has leveled the playing field for business. Today, any ambitious innovator can easily introduce a new application or product that can reinvent business models and transform the client experience. In their Day 2 Keynote at 19th Cloud Expo, Mercer Rowe, IBM Vice President of Strategic Alliances, and Raejeanne Skillern, Intel Vice President of Data Center Group and G...
Feb. 26, 2017 06:00 AM EST Reads: 4,272
Financial Technology has become a topic of intense interest throughout the cloud developer and enterprise IT communities. Accordingly, attendees at the upcoming 20th Cloud Expo at the Javits Center in New York, June 6-8, 2017, will find fresh new content in a new track called FinTech.
Feb. 26, 2017 06:00 AM EST Reads: 6,286
@GonzalezCarmen has been ranked the Number One Influencer and @ThingsExpo has been named the Number One Brand in the “M2M 2016: Top 100 Influencers and Brands” by Onalytica. Onalytica analyzed tweets over the last 6 months mentioning the keywords M2M OR “Machine to Machine.” They then identified the top 100 most influential brands and individuals leading the discussion on Twitter.
Feb. 26, 2017 06:00 AM EST Reads: 5,774
20th Cloud Expo, taking place June 6-8, 2017, at the Javits Center in New York City, NY, will feature technical sessions from a rock star conference faculty and the leading industry players in the world. Cloud computing is now being embraced by a majority of enterprises of all sizes. Yesterday's debate about public vs. private has transformed into the reality of hybrid cloud: a recent survey shows that 74% of enterprises have a hybrid cloud strategy.
Feb. 26, 2017 05:00 AM EST Reads: 4,844
Manufacturers are embracing the Industrial Internet the same way consumers are leveraging Fitbits – to improve overall health and wellness. Both can provide consistent measurement, visibility, and suggest performance improvements customized to help reach goals. Fitbit users can view real-time data and make adjustments to increase their activity. In his session at @ThingsExpo, Mark Bernardo Professional Services Leader, Americas, at GE Digital, discussed how leveraging the Industrial Internet and...
Feb. 26, 2017 03:45 AM EST Reads: 8,495
SYS-CON Events announced today that delaPlex will exhibit at SYS-CON's @CloudExpo, which will take place on June 6-8, 2017, at the Javits Center in New York City, NY. delaPlex pioneered Software Development as a Service (SDaaS), which provides scalable resources to build, test, and deploy software. It’s a fast and more reliable way to develop a new product or expand your in-house team.
Feb. 26, 2017 03:15 AM EST Reads: 2,027
Web Real-Time Communication APIs have quickly revolutionized what browsers are capable of. In addition to video and audio streams, we can now bi-directionally send arbitrary data over WebRTC's PeerConnection Data Channels. With the advent of Progressive Web Apps and new hardware APIs such as WebBluetooh and WebUSB, we can finally enable users to stitch together the Internet of Things directly from their browsers while communicating privately and securely in a decentralized way.
Feb. 26, 2017 03:00 AM EST Reads: 2,760
Information technology (IT) advances are transforming the way we innovate in business, thereby disrupting the old guard and their predictable status-quo. It’s creating global market turbulence. Industries are converging, and new opportunities and threats are emerging, like never before. So, how are savvy chief information officers (CIOs) leading this transition? Back in 2015, the IBM Institute for Business Value conducted a market study that included the findings from over 1,800 CIO interviews ...
Feb. 26, 2017 02:30 AM EST Reads: 2,338
"Matrix is an ambitious open standard and implementation that's set up to break down the fragmentation problems that exist in IP messaging and VoIP communication," explained John Woolf, Technical Evangelist at Matrix, in this SYS-CON.tv interview at @ThingsExpo, held Nov 4–6, 2014, at the Santa Clara Convention Center in Santa Clara, CA.
Feb. 26, 2017 02:30 AM EST Reads: 13,723
Feb. 26, 2017 02:00 AM EST Reads: 4,781
"We host and fully manage cloud data services, whether we store, the data, move the data, or run analytics on the data," stated Kamal Shannak, Senior Development Manager, Cloud Data Services, IBM, in this SYS-CON.tv interview at 18th Cloud Expo, held June 7-9, 2016, at the Javits Center in New York City, NY.
Feb. 26, 2017 01:45 AM EST Reads: 6,219
While DevOps most critically and famously fosters collaboration, communication, and integration through cultural change, culture is more of an output than an input. In order to actively drive cultural evolution, organizations must make substantial organizational and process changes, and adopt new technologies, to encourage a DevOps culture. Moderated by Andi Mann, panelists discussed how to balance these three pillars of DevOps, where to focus attention (and resources), where organizations might...
Feb. 26, 2017 01:30 AM EST Reads: 5,225
Zerto exhibited at SYS-CON's 18th International Cloud Expo®, which took place at the Javits Center in New York City, NY, in June 2016. Zerto is committed to keeping enterprise and cloud IT running 24/7 by providing innovative, simple, reliable and scalable business continuity software solutions. Through the Zerto Cloud Continuity Platform™, organizations can seamlessly move and protect virtualized workloads between public, private and hybrid clouds. The company’s flagship product, Zerto Virtual...
Feb. 26, 2017 01:15 AM EST Reads: 1,745
Some people worry that OpenStack is more flash then substance; however, for many customers this could not be farther from the truth. No other technology equalizes the playing field between vendors while giving your internal teams better access than ever to infrastructure when they need it. In his session at 20th Cloud Expo, Chris Brown, a Solutions Marketing Manager at Nutanix, will talk through some real-world OpenStack deployments and look into the ways this can benefit customers of all sizes....
Feb. 26, 2017 12:00 AM EST Reads: 1,507