Welcome!

News Feed Item

Frost & Sullivan Lauds BioScale for Developing a Revolutionary Protein Analysis Platform Based on its ViBE Platform

- The ViBE addresses limitations with traditional technologies such as ELISA, western blot and IHC and enables the measurement of low-expressing proteins, which were inaccessible through other techniques available in the market

MOUNTAIN VIEW, California, Jan. 22, 2014 /PRNewswire/ -- Based on its recent analysis of the protein analysis market, Frost & Sullivan recognizes BioScale, Inc. with the North America Frost & Sullivan Award for New Product Innovation. BioScale has reduced the bottlenecks and limitations common in conventional protein analysis technologies by developing a fast, simple, ultra-sensitive, and flexible technology. Its revolutionary ViBE platform is rapidly gaining traction among pharmaceutical companies and high-profile academic and government laboratories, and is proving to be a market-changing technology with a wide scope of applications.

BioScale's ViBE protein measurement technology platform provides highly-sensitive, robust, and reproducible protein detection and quantitation in a fully-automated walk-away instrument. The system is powered by the company's proprietary Acoustic Membrane MicroParticle (AMMP) technology, which combines magnetic microparticle analyte captured with microelectromechanical systems (MEMS) sensors for non-optical acoustic detection.

"BioScale's acoustic measurement system has many advantages over competing technologies, such as the ability to measure previously unmeasureable data such as quantitation of biomarkers in tumors, misfolded proteins, and heteromers. In addition, the ViBE's sensitivity levels have significant implications for biomarker discovery and detection for diagnostics and drug development," said Frost & Sullivan Senior Industry Analyst Christi Bird. "However, its biggest advantage is its scalability and ability to expand into a broad range of applications outside of protein analysis in the future."

Before developing its path-breaking product, BioScale identified the shortcomings of the existing protein techniques— artifacts due to optical techniques, slow sample preparation, tedious manual steps, difficult assay development, baseline noise and interference, inadequate sensitivity, high variability, and slow time-to-results. To solve these issues, BioScale focused on automating the process, simplifying assay development, and swapping optical detection for a non-optical, acoustic-based detection system.

Using a MEMS sensor for detection has allowed the company to enhance the sensitivity, miniaturization, direct measurement, and affordability of its protein analysis technology. This detection system replaces the bulky, indirect, and expensive optical detection that is traditionally used in proteomic laboratories. MEMS sensors also eliminate the issues of light scattering, quenching, and fluorescence interference typical of optical detection systems.

Meanwhile, the use of magnetic microparticles for capture reduces sample matrix interference and provides a rapid transport system from the cartridge cells to the sensor surface. It aids the analysis of specific proteins down to very low levels quickly, accurately, and affordably. Furthermore, as an open system, the ViBE platform allows researchers to use their own antibodies and reagents to develop sandwich assays, a convenient and economical feature.

"Frost & Sullivan's competitive benchmarking shows that the flexibility to meet the researcher's needs with many customizable components, such as assay strategy and format, flow rate, reagent usage, and adjusting incubation time versus sensitivity, is key to the success of the platform," noted Bird. "In addition, the technology's application can expand far beyond protein analysis, adding further value to the platform as new applications arise."

BioScale's AMMP technology can measure analytes in a large number of sample matrices, such as cell culture, whole blood, serum, plasma, urine, stool, and food, which provides clear future application potential in clinical diagnostics and food testing. In addition, the technology can measure many analyte types outside of protein, such as DNA, small molecules, whole cells, bacteria, viruses, and hormones. In the future, Frost & Sullivan expects BioScale's technology to be utilized in a wide range of applications in protein research, genomics, clinical diagnostics, biomarker discovery, and throughout the drug discovery pipeline.

Each year, Frost & Sullivan presents this award to the company that has developed an innovative element in a product by leveraging leading-edge technologies. The award recognizes the value-added features/benefits of the product and the increased ROI it offers customers, which, in turn, increases customer acquisition and overall market penetration potential.

Frost & Sullivan Best Practices Awards recognize companies in a variety of regional and global markets for demonstrating outstanding achievement and superior performance in areas such as leadership, technological innovation, customer service and strategic product development. Industry analysts compare market participants and measure performance through in-depth interviews, analysis and extensive secondary research to identify best practices in the industry.

About BioScale, Inc.

BioScale manufactures and markets the ViBE™ platform, a novel protein measurement technology enabling highly sensitive, automated Acoustic Immunoassays™ to accelerate drug discovery, development and production of biological and pharmaceutical products. The sensitivity, precision and walk-away capabilities of our non-optical AMMP technology enables customers to achieve break-through advancements in protein research that were not previously attainable via tradition ELISA, Western blot and IHC methods, allowing ultra-sensitive detection of proteins in complex biological samples. BioScale is headquartered in Lexington, MA.

About Frost & Sullivan

Frost & Sullivan, the Growth Partnership Company, works in collaboration with clients to leverage visionary innovation that addresses the global challenges and related growth opportunities that will make or break today's market participants.

Our "Growth Partnership" supports clients by addressing these opportunities and incorporating two key elements driving visionary innovation: The Integrated Value Proposition and The Partnership Infrastructure.

  • The Integrated Value Proposition provides support to our clients throughout all phases of their journey to visionary innovation including: research, analysis, strategy, vision, innovation and implementation.
  • The Partnership Infrastructure is entirely unique as it constructs the foundation upon which visionary innovation becomes possible. This includes our 360 degree research, comprehensive industry coverage, career best practices as well as our global footprint of more than 40 offices.

For more than 50 years, we have been developing growth strategies for the global 1000, emerging businesses, the public sector and the investment community. Is your organization prepared for the next profound wave of industry convergence, disruptive technologies, increasing competitive intensity, Mega Trends, breakthrough best practices, changing customer dynamics and emerging economies?

Contact Us: Start the discussion

Join Us: Join our community

Subscribe: Newsletter on "the next big thing"

Register: Gain access to visionary innovation

Contact:

Mireya Espinoza
P: 210. 247.3870
F: 210.348.1003
E: [email protected]

BioScale Inc. Contact:

Name: Ashley Saab
P: 781-430-6876
F: 781-430-6801
E: [email protected]

More Stories By PR Newswire

Copyright © 2007 PR Newswire. All rights reserved. Republication or redistribution of PRNewswire content is expressly prohibited without the prior written consent of PRNewswire. PRNewswire shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.

Latest Stories
As Marc Andreessen says software is eating the world. Everything is rapidly moving toward being software-defined – from our phones and cars through our washing machines to the datacenter. However, there are larger challenges when implementing software defined on a larger scale - when building software defined infrastructure. In his session at 16th Cloud Expo, Boyan Ivanov, CEO of StorPool, provided some practical insights on what, how and why when implementing "software-defined" in the datacent...
You know you need the cloud, but you’re hesitant to simply dump everything at Amazon since you know that not all workloads are suitable for cloud. You know that you want the kind of ease of use and scalability that you get with public cloud, but your applications are architected in a way that makes the public cloud a non-starter. You’re looking at private cloud solutions based on hyperconverged infrastructure, but you’re concerned with the limits inherent in those technologies.
ChatOps is an emerging topic that has led to the wide availability of integrations between group chat and various other tools/platforms. Currently, HipChat is an extremely powerful collaboration platform due to the various ChatOps integrations that are available. However, DevOps automation can involve orchestration and complex workflows. In his session at @DevOpsSummit at 20th Cloud Expo, Himanshu Chhetri, CTO at Addteq, will cover practical examples and use cases such as self-provisioning infra...
Blockchain. A day doesn’t seem to go by without seeing articles and discussions about the technology. According to PwC executive Seamus Cushley, approximately $1.4B has been invested in blockchain just last year. In Gartner’s recent hype cycle for emerging technologies, blockchain is approaching the peak. It is considered by Gartner as one of the ‘Key platform-enabling technologies to track.’ While there is a lot of ‘hype vs reality’ discussions going on, there is no arguing that blockchain is b...
Leading companies, from the Global Fortune 500 to the smallest companies, are adopting hybrid cloud as the path to business advantage. Hybrid cloud depends on cloud services and on-premises infrastructure working in unison. Successful implementations require new levels of data mobility, enabled by an automated and seamless flow across on-premises and cloud resources. In his general session at 21st Cloud Expo, Greg Tevis, an IBM Storage Software Technical Strategist and Customer Solution Architec...
The need for greater agility and scalability necessitated the digital transformation in the form of following equation: monolithic to microservices to serverless architecture (FaaS). To keep up with the cut-throat competition, the organisations need to update their technology stack to make software development their differentiating factor. Thus microservices architecture emerged as a potential method to provide development teams with greater flexibility and other advantages, such as the abili...
Nordstrom is transforming the way that they do business and the cloud is the key to enabling speed and hyper personalized customer experiences. In his session at 21st Cloud Expo, Ken Schow, VP of Engineering at Nordstrom, discussed some of the key learnings and common pitfalls of large enterprises moving to the cloud. This includes strategies around choosing a cloud provider(s), architecture, and lessons learned. In addition, he covered some of the best practices for structured team migration an...
Product connectivity goes hand and hand these days with increased use of personal data. New IoT devices are becoming more personalized than ever before. In his session at 22nd Cloud Expo | DXWorld Expo, Nicolas Fierro, CEO of MIMIR Blockchain Solutions, will discuss how in order to protect your data and privacy, IoT applications need to embrace Blockchain technology for a new level of product security never before seen - or needed.
The use of containers by developers -- and now increasingly IT operators -- has grown from infatuation to deep and abiding love. But as with any long-term affair, the honeymoon soon leads to needing to live well together ... and maybe even getting some relationship help along the way. And so it goes with container orchestration and automation solutions, which are rapidly emerging as the means to maintain the bliss between rapid container adoption and broad container use among multiple cloud host...
Blockchain is a shared, secure record of exchange that establishes trust, accountability and transparency across business networks. Supported by the Linux Foundation's open source, open-standards based Hyperledger Project, Blockchain has the potential to improve regulatory compliance, reduce cost as well as advance trade. Are you curious about how Blockchain is built for business? In her session at 21st Cloud Expo, René Bostic, Technical VP of the IBM Cloud Unit in North America, discussed the b...
In his general session at 21st Cloud Expo, Greg Dumas, Calligo’s Vice President and G.M. of US operations, discussed the new Global Data Protection Regulation and how Calligo can help business stay compliant in digitally globalized world. Greg Dumas is Calligo's Vice President and G.M. of US operations. Calligo is an established service provider that provides an innovative platform for trusted cloud solutions. Calligo’s customers are typically most concerned about GDPR compliance, application p...
Imagine if you will, a retail floor so densely packed with sensors that they can pick up the movements of insects scurrying across a store aisle. Or a component of a piece of factory equipment so well-instrumented that its digital twin provides resolution down to the micrometer.
In his keynote at 18th Cloud Expo, Andrew Keys, Co-Founder of ConsenSys Enterprise, provided an overview of the evolution of the Internet and the Database and the future of their combination – the Blockchain. Andrew Keys is Co-Founder of ConsenSys Enterprise. He comes to ConsenSys Enterprise with capital markets, technology and entrepreneurial experience. Previously, he worked for UBS investment bank in equities analysis. Later, he was responsible for the creation and distribution of life settle...
The cloud era has reached the stage where it is no longer a question of whether a company should migrate, but when. Enterprises have embraced the outsourcing of where their various applications are stored and who manages them, saving significant investment along the way. Plus, the cloud has become a defining competitive edge. Companies that fail to successfully adapt risk failure. The media, of course, continues to extol the virtues of the cloud, including how easy it is to get there. Migrating...
No hype cycles or predictions of a gazillion things here. IoT is here. You get it. You know your business and have great ideas for a business transformation strategy. What comes next? Time to make it happen. In his session at @ThingsExpo, Jay Mason, an Associate Partner of Analytics, IoT & Cybersecurity at M&S Consulting, presented a step-by-step plan to develop your technology implementation strategy. He also discussed the evaluation of communication standards and IoT messaging protocols, data...