Welcome!

News Feed Item

Frost & Sullivan Lauds BioScale for Developing a Revolutionary Protein Analysis Platform Based on its ViBE Platform

- The ViBE addresses limitations with traditional technologies such as ELISA, western blot and IHC and enables the measurement of low-expressing proteins, which were inaccessible through other techniques available in the market

MOUNTAIN VIEW, California, Jan. 22, 2014 /PRNewswire/ -- Based on its recent analysis of the protein analysis market, Frost & Sullivan recognizes BioScale, Inc. with the North America Frost & Sullivan Award for New Product Innovation. BioScale has reduced the bottlenecks and limitations common in conventional protein analysis technologies by developing a fast, simple, ultra-sensitive, and flexible technology. Its revolutionary ViBE platform is rapidly gaining traction among pharmaceutical companies and high-profile academic and government laboratories, and is proving to be a market-changing technology with a wide scope of applications.

BioScale's ViBE protein measurement technology platform provides highly-sensitive, robust, and reproducible protein detection and quantitation in a fully-automated walk-away instrument. The system is powered by the company's proprietary Acoustic Membrane MicroParticle (AMMP) technology, which combines magnetic microparticle analyte captured with microelectromechanical systems (MEMS) sensors for non-optical acoustic detection.

"BioScale's acoustic measurement system has many advantages over competing technologies, such as the ability to measure previously unmeasureable data such as quantitation of biomarkers in tumors, misfolded proteins, and heteromers. In addition, the ViBE's sensitivity levels have significant implications for biomarker discovery and detection for diagnostics and drug development," said Frost & Sullivan Senior Industry Analyst Christi Bird. "However, its biggest advantage is its scalability and ability to expand into a broad range of applications outside of protein analysis in the future."

Before developing its path-breaking product, BioScale identified the shortcomings of the existing protein techniques— artifacts due to optical techniques, slow sample preparation, tedious manual steps, difficult assay development, baseline noise and interference, inadequate sensitivity, high variability, and slow time-to-results. To solve these issues, BioScale focused on automating the process, simplifying assay development, and swapping optical detection for a non-optical, acoustic-based detection system.

Using a MEMS sensor for detection has allowed the company to enhance the sensitivity, miniaturization, direct measurement, and affordability of its protein analysis technology. This detection system replaces the bulky, indirect, and expensive optical detection that is traditionally used in proteomic laboratories. MEMS sensors also eliminate the issues of light scattering, quenching, and fluorescence interference typical of optical detection systems.

Meanwhile, the use of magnetic microparticles for capture reduces sample matrix interference and provides a rapid transport system from the cartridge cells to the sensor surface. It aids the analysis of specific proteins down to very low levels quickly, accurately, and affordably. Furthermore, as an open system, the ViBE platform allows researchers to use their own antibodies and reagents to develop sandwich assays, a convenient and economical feature.

"Frost & Sullivan's competitive benchmarking shows that the flexibility to meet the researcher's needs with many customizable components, such as assay strategy and format, flow rate, reagent usage, and adjusting incubation time versus sensitivity, is key to the success of the platform," noted Bird. "In addition, the technology's application can expand far beyond protein analysis, adding further value to the platform as new applications arise."

BioScale's AMMP technology can measure analytes in a large number of sample matrices, such as cell culture, whole blood, serum, plasma, urine, stool, and food, which provides clear future application potential in clinical diagnostics and food testing. In addition, the technology can measure many analyte types outside of protein, such as DNA, small molecules, whole cells, bacteria, viruses, and hormones. In the future, Frost & Sullivan expects BioScale's technology to be utilized in a wide range of applications in protein research, genomics, clinical diagnostics, biomarker discovery, and throughout the drug discovery pipeline.

Each year, Frost & Sullivan presents this award to the company that has developed an innovative element in a product by leveraging leading-edge technologies. The award recognizes the value-added features/benefits of the product and the increased ROI it offers customers, which, in turn, increases customer acquisition and overall market penetration potential.

Frost & Sullivan Best Practices Awards recognize companies in a variety of regional and global markets for demonstrating outstanding achievement and superior performance in areas such as leadership, technological innovation, customer service and strategic product development. Industry analysts compare market participants and measure performance through in-depth interviews, analysis and extensive secondary research to identify best practices in the industry.

About BioScale, Inc.

BioScale manufactures and markets the ViBE™ platform, a novel protein measurement technology enabling highly sensitive, automated Acoustic Immunoassays™ to accelerate drug discovery, development and production of biological and pharmaceutical products. The sensitivity, precision and walk-away capabilities of our non-optical AMMP technology enables customers to achieve break-through advancements in protein research that were not previously attainable via tradition ELISA, Western blot and IHC methods, allowing ultra-sensitive detection of proteins in complex biological samples. BioScale is headquartered in Lexington, MA.

About Frost & Sullivan

Frost & Sullivan, the Growth Partnership Company, works in collaboration with clients to leverage visionary innovation that addresses the global challenges and related growth opportunities that will make or break today's market participants.

Our "Growth Partnership" supports clients by addressing these opportunities and incorporating two key elements driving visionary innovation: The Integrated Value Proposition and The Partnership Infrastructure.

  • The Integrated Value Proposition provides support to our clients throughout all phases of their journey to visionary innovation including: research, analysis, strategy, vision, innovation and implementation.
  • The Partnership Infrastructure is entirely unique as it constructs the foundation upon which visionary innovation becomes possible. This includes our 360 degree research, comprehensive industry coverage, career best practices as well as our global footprint of more than 40 offices.

For more than 50 years, we have been developing growth strategies for the global 1000, emerging businesses, the public sector and the investment community. Is your organization prepared for the next profound wave of industry convergence, disruptive technologies, increasing competitive intensity, Mega Trends, breakthrough best practices, changing customer dynamics and emerging economies?

Contact Us: Start the discussion

Join Us: Join our community

Subscribe: Newsletter on "the next big thing"

Register: Gain access to visionary innovation

Contact:

Mireya Espinoza
P: 210. 247.3870
F: 210.348.1003
E: [email protected]

BioScale Inc. Contact:

Name: Ashley Saab
P: 781-430-6876
F: 781-430-6801
E: [email protected]

More Stories By PR Newswire

Copyright © 2007 PR Newswire. All rights reserved. Republication or redistribution of PRNewswire content is expressly prohibited without the prior written consent of PRNewswire. PRNewswire shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.

Latest Stories
Data is an unusual currency; it is not restricted by the same transactional limitations as money or people. In fact, the more that you leverage your data across multiple business use cases, the more valuable it becomes to the organization. And the same can be said about the organization’s analytics. In his session at 19th Cloud Expo, Bill Schmarzo, CTO for the Big Data Practice at EMC, will introduce a methodology for capturing, enriching and sharing data (and analytics) across the organizati...
DevOps at Cloud Expo – being held November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA – announces that its Call for Papers is open. Born out of proven success in agile development, cloud computing, and process automation, DevOps is a macro trend you cannot afford to miss. From showcase success stories from early adopters and web-scale businesses, DevOps is expanding to organizations of all sizes, including the world's largest enterprises – and delivering real results. Am...
IoT is fundamentally transforming the auto industry, turning the vehicle into a hub for connected services, including safety, infotainment and usage-based insurance. Auto manufacturers – and businesses across all verticals – have built an entire ecosystem around the Connected Car, creating new customer touch points and revenue streams. In his session at @ThingsExpo, Macario Namie, Head of IoT Strategy at Cisco Jasper, will share real-world examples of how IoT transforms the car from a static p...
The many IoT deployments around the world are busy integrating smart devices and sensors into their enterprise IT infrastructures. Yet all of this technology – and there are an amazing number of choices – is of no use without the software to gather, communicate, and analyze the new data flows. Without software, there is no IT. In this power panel at @ThingsExpo, moderated by Conference Chair Roger Strukhoff, panelists will look at the protocols that communicate data and the emerging data analy...
The vision of a connected smart home is becoming reality with the application of integrated wireless technologies in devices and appliances. The use of standardized and TCP/IP networked wireless technologies in line-powered and battery operated sensors and controls has led to the adoption of radios in the 2.4GHz band, including Wi-Fi, BT/BLE and 802.15.4 applied ZigBee and Thread. This is driving the need for robust wireless coexistence for multiple radios to ensure throughput performance and th...
I’m going to cry tonight, long and hard. I’ll do so as I remember and mourn Jeremy Geelan. I knew Jeremy for almost 20 years, from the time he showed up one day at Cloud Expo’s headquarters in Bergen County, New Jersey, and went to work. The show wasn’t called Cloud Expo then, of course – it was still known as Java Edge, a pioneering event that grabbed developers, architects, and enterprise IT users alike for twice-yearly confabs. Jeremy didn’t have a job there, or even a job offer. He was s...
SYS-CON Events announced today that China Unicom will exhibit at the 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. China United Network Communications Group Co. Ltd ("China Unicom") was officially established in 2009 on the basis of the merger of former China Netcom and former China Unicom. China Unicom mainly operates a full range of telecommunications services including mobile broadband (GSM, WCDMA, LTE F...
The Transparent Cloud-computing Consortium (abbreviation: T-Cloud Consortium) will conduct research activities into changes in the computing model as a result of collaboration between "device" and "cloud" and the creation of new value and markets through organic data processing High speed and high quality networks, and dramatic improvements in computer processing capabilities, have greatly changed the nature of applications and made the storing and processing of data on the network commonplace.
Video experiences should be unique and exciting! But that doesn’t mean you need to patch all the pieces yourself. Users demand rich and engaging experiences and new ways to connect with you. But creating robust video applications at scale can be complicated, time-consuming and expensive. In his session at @ThingsExpo, Zohar Babin, Vice President of Platform, Ecosystem and Community at Kaltura, will discuss how VPaaS enables you to move fast, creating scalable video experiences that reach your...
In his session at @DevOpsSummit at 19th Cloud Expo, Robert Doyle, lead architect at eCube Systems, will examine the issues and need for an agile infrastructure and show the advantages of capturing developer knowledge in an exportable file for migration into production. He will introduce the use of NXTmonitor, a next-generation DevOps tool that captures application environments, dependencies and start/stop procedures in a portable configuration file with an easy-to-use GUI. In addition to captu...
All clouds are not equal. To succeed in a DevOps context, organizations should plan to develop/deploy apps across a choice of on-premise and public clouds simultaneously depending on the business needs. This is where the concept of the Lean Cloud comes in - resting on the idea that you often need to relocate your app modules over their life cycles for both innovation and operational efficiency in the cloud. In his session at @DevOpsSummit at19th Cloud Expo, Valentin (Val) Bercovici, CTO of So...
Big Data has been changing the world. IoT fuels the further transformation recently. How are Big Data and IoT related? In his session at @BigDataExpo, Tony Shan, a renowned visionary and thought leader, will explore the interplay of Big Data and IoT. He will anatomize Big Data and IoT separately in terms of what, which, why, where, when, who, how and how much. He will then analyze the relationship between IoT and Big Data, specifically the drilldown of how the 4Vs of Big Data (Volume, Variety,...
SYS-CON Events announced today that Pulzze Systems will exhibit at the 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. Pulzze Systems, Inc. provides infrastructure products for the Internet of Things to enable any connected device and system to carry out matched operations without programming. For more information, visit http://www.pulzzesystems.com.
If you’re responsible for an application that depends on the data or functionality of various IoT endpoints – either sensors or devices – your brand reputation depends on the security, reliability, and compliance of its many integrated parts. If your application fails to deliver the expected business results, your customers and partners won't care if that failure stems from the code you developed or from a component that you integrated. What can you do to ensure that the endpoints work as expect...
SYS-CON Events announced today that Secure Channels will exhibit at the 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. The bedrock of Secure Channels Technology is a uniquely modified and enhanced process based on superencipherment. Superencipherment is the process of encrypting an already encrypted message one or more times, either using the same or a different algorithm.