Welcome!

News Feed Item

Frost & Sullivan Lauds BioScale for Developing a Revolutionary Protein Analysis Platform Based on its ViBE Platform

The ViBE addresses limitations with traditional technologies such as ELISA, western blot and IHC and enables the measurement of low-expressing proteins, which were inaccessible through other techniques available in the market

MOUNTAIN VIEW, Calif., Jan. 22, 2014 /PRNewswire/ -- Based on its recent analysis of the protein analysis market, Frost & Sullivan recognizes BioScale, Inc. with the North America Frost & Sullivan Award for New Product Innovation. BioScale has reduced the bottlenecks and limitations common in conventional protein analysis technologies by developing a fast, simple, ultra-sensitive, and flexible technology. Its revolutionary ViBE platform is rapidly gaining traction among pharmaceutical companies and high-profile academic and government laboratories, and is proving to be a market-changing technology with a wide scope of applications.

BioScale's ViBE protein measurement technology platform provides highly-sensitive, robust, and reproducible protein detection and quantitation in a fully-automated walk-away instrument. The system is powered by the company's proprietary Acoustic Membrane MicroParticle (AMMP) technology, which combines magnetic microparticle analyte captured with microelectromechanical systems (MEMS) sensors for non-optical acoustic detection.

"BioScale's acoustic measurement system has many advantages over competing technologies, such as the ability to measure previously unmeasureable data such as quantitation of biomarkers in tumors, misfolded proteins, and heteromers. In addition, the ViBE's sensitivity levels have significant implications for biomarker discovery and detection for diagnostics and drug development," said Frost & Sullivan Senior Industry Analyst Christi Bird. "However, its biggest advantage is its scalability and ability to expand into a broad range of applications outside of protein analysis in the future."

Before developing its path-breaking product, BioScale identified the shortcomings of the existing protein techniques— artifacts due to optical techniques, slow sample preparation, tedious manual steps, difficult assay development, baseline noise and interference, inadequate sensitivity, high variability, and slow time-to-results. To solve these issues, BioScale focused on automating the process, simplifying assay development, and swapping optical detection for a non-optical, acoustic-based detection system.

Using a MEMS sensor for detection has allowed the company to enhance the sensitivity, miniaturization, direct measurement, and affordability of its protein analysis technology. This detection system replaces the bulky, indirect, and expensive optical detection that is traditionally used in proteomic laboratories.  MEMS sensors also eliminate the issues of light scattering, quenching, and fluorescence interference typical of optical detection systems.

Meanwhile, the use of magnetic microparticles for capture reduces sample matrix interference and provides a rapid transport system from the cartridge cells to the sensor surface. It aids the analysis of specific proteins down to very low levels quickly, accurately, and affordably. Furthermore, as an open system, the ViBE platform allows researchers to use their own antibodies and reagents to develop sandwich assays, a convenient and economical feature.

"Frost & Sullivan's competitive benchmarking shows that the flexibility to meet the researcher's needs with many customizable components, such as assay strategy and format, flow rate, reagent usage, and adjusting incubation time versus sensitivity, is key to the success of the platform," noted Bird. "In addition, the technology's application can expand far beyond protein analysis, adding further value to the platform as new applications arise."

BioScale's AMMP technology can measure analytes in a large number of sample matrices, such as cell culture, whole blood, serum, plasma, urine, stool, and food, which provides clear future application potential in clinical diagnostics and food testing. In addition, the technology can measure many analyte types outside of protein, such as DNA, small molecules, whole cells, bacteria, viruses, and hormones. In the future, Frost & Sullivan expects BioScale's technology to be utilized in a wide range of applications in protein research, genomics, clinical diagnostics, biomarker discovery, and throughout the drug discovery pipeline.

Each year, Frost & Sullivan presents this award to the company that has developed an innovative element in a product by leveraging leading-edge technologies. The award recognizes the value-added features/benefits of the product and the increased ROI it offers customers, which, in turn, increases customer acquisition and overall market penetration potential.

Frost & Sullivan Best Practices Awards recognize companies in a variety of regional and global markets for demonstrating outstanding achievement and superior performance in areas such as leadership, technological innovation, customer service and strategic product development. Industry analysts compare market participants and measure performance through in-depth interviews, analysis and extensive secondary research to identify best practices in the industry.

About BioScale, Inc.

BioScale manufactures and markets the ViBE™ platform, a novel protein measurement technology enabling highly sensitive, automated Acoustic Immunoassays™ to accelerate drug discovery, development and production of biological and pharmaceutical products.  The sensitivity, precision and walk-away capabilities of our non-optical AMMP technology enables customers to achieve break-through advancements in protein research that were not previously attainable via tradition ELISA, Western blot and IHC methods, allowing ultra-sensitive detection of proteins in complex biological samples. BioScale is headquartered in Lexington, MA.

About Frost & Sullivan

Frost & Sullivan, the Growth Partnership Company, works in collaboration with clients to leverage visionary innovation that addresses the global challenges and related growth opportunities that will make or break today's market participants.

Our "Growth Partnership" supports clients by addressing these opportunities and incorporating two key elements driving visionary innovation: The Integrated Value Proposition and The Partnership Infrastructure.

  • The Integrated Value Proposition provides support to our clients throughout all phases of their journey to visionary innovation including: research, analysis, strategy, vision, innovation and implementation.
  • The Partnership Infrastructure is entirely unique as it constructs the foundation upon which visionary innovation becomes possible. This includes our 360 degree research, comprehensive industry coverage, career best practices as well as our global footprint of more than 40 offices.

For more than 50 years, we have been developing growth strategies for the global 1000, emerging businesses, the public sector and the investment community. Is your organization prepared for the next profound wave of industry convergence, disruptive technologies, increasing competitive intensity, Mega Trends, breakthrough best practices, changing customer dynamics and emerging economies?

Contact Us:     Start the discussion

Join Us:           Join our community

Subscribe:       Newsletter on "the next big thing"

Register:         Gain access to visionary innovation

Contact:

Mireya Espinoza
P: 210. 247.3870
F: 210.348.1003
E: [email protected]

BioScale Inc. Contact:

Name: Ashley Saab
P: 781-430-6876
F: 781-430-6801
E: [email protected]

SOURCE Frost & Sullivan

More Stories By PR Newswire

Copyright © 2007 PR Newswire. All rights reserved. Republication or redistribution of PRNewswire content is expressly prohibited without the prior written consent of PRNewswire. PRNewswire shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.

Latest Stories
Sometimes I write a blog just to formulate and organize a point of view, and I think it’s time that I pull together the bounty of excellent information about Machine Learning. This is a topic with which business leaders must become comfortable, especially tomorrow’s business leaders (tip for my next semester University of San Francisco business students!). Machine learning is a key capability that will help organizations drive optimization and monetization opportunities, and there have been some...
The question before companies today is not whether to become intelligent, it’s a question of how and how fast. The key is to adopt and deploy an intelligent application strategy while simultaneously preparing to scale that intelligence. In her session at 21st Cloud Expo, Sangeeta Chakraborty, Chief Customer Officer at Ayasdi, provided a tactical framework to become a truly intelligent enterprise, including how to identify the right applications for AI, how to build a Center of Excellence to oper...
While some developers care passionately about how data centers and clouds are architected, for most, it is only the end result that matters. To the majority of companies, technology exists to solve a business problem, and only delivers value when it is solving that problem. 2017 brings the mainstream adoption of containers for production workloads. In his session at 21st Cloud Expo, Ben McCormack, VP of Operations at Evernote, discussed how data centers of the future will be managed, how the p...
"Storpool does only block-level storage so we do one thing extremely well. The growth in data is what drives the move to software-defined technologies in general and software-defined storage," explained Boyan Ivanov, CEO and co-founder at StorPool, in this SYS-CON.tv interview at 16th Cloud Expo, held June 9-11, 2015, at the Javits Center in New York City.
A strange thing is happening along the way to the Internet of Things, namely far too many devices to work with and manage. It has become clear that we'll need much higher efficiency user experiences that can allow us to more easily and scalably work with the thousands of devices that will soon be in each of our lives. Enter the conversational interface revolution, combining bots we can literally talk with, gesture to, and even direct with our thoughts, with embedded artificial intelligence, whic...
ChatOps is an emerging topic that has led to the wide availability of integrations between group chat and various other tools/platforms. Currently, HipChat is an extremely powerful collaboration platform due to the various ChatOps integrations that are available. However, DevOps automation can involve orchestration and complex workflows. In his session at @DevOpsSummit at 20th Cloud Expo, Himanshu Chhetri, CTO at Addteq, will cover practical examples and use cases such as self-provisioning infra...
As DevOps methodologies expand their reach across the enterprise, organizations face the daunting challenge of adapting related cloud strategies to ensure optimal alignment, from managing complexity to ensuring proper governance. How can culture, automation, legacy apps and even budget be reexamined to enable this ongoing shift within the modern software factory? In her Day 2 Keynote at @DevOpsSummit at 21st Cloud Expo, Aruna Ravichandran, VP, DevOps Solutions Marketing, CA Technologies, was jo...
As Marc Andreessen says software is eating the world. Everything is rapidly moving toward being software-defined – from our phones and cars through our washing machines to the datacenter. However, there are larger challenges when implementing software defined on a larger scale - when building software defined infrastructure. In his session at 16th Cloud Expo, Boyan Ivanov, CEO of StorPool, provided some practical insights on what, how and why when implementing "software-defined" in the datacent...
Blockchain. A day doesn’t seem to go by without seeing articles and discussions about the technology. According to PwC executive Seamus Cushley, approximately $1.4B has been invested in blockchain just last year. In Gartner’s recent hype cycle for emerging technologies, blockchain is approaching the peak. It is considered by Gartner as one of the ‘Key platform-enabling technologies to track.’ While there is a lot of ‘hype vs reality’ discussions going on, there is no arguing that blockchain is b...
Blockchain is a shared, secure record of exchange that establishes trust, accountability and transparency across business networks. Supported by the Linux Foundation's open source, open-standards based Hyperledger Project, Blockchain has the potential to improve regulatory compliance, reduce cost as well as advance trade. Are you curious about how Blockchain is built for business? In her session at 21st Cloud Expo, René Bostic, Technical VP of the IBM Cloud Unit in North America, discussed the b...
You know you need the cloud, but you’re hesitant to simply dump everything at Amazon since you know that not all workloads are suitable for cloud. You know that you want the kind of ease of use and scalability that you get with public cloud, but your applications are architected in a way that makes the public cloud a non-starter. You’re looking at private cloud solutions based on hyperconverged infrastructure, but you’re concerned with the limits inherent in those technologies.
Is advanced scheduling in Kubernetes achievable?Yes, however, how do you properly accommodate every real-life scenario that a Kubernetes user might encounter? How do you leverage advanced scheduling techniques to shape and describe each scenario in easy-to-use rules and configurations? In his session at @DevOpsSummit at 21st Cloud Expo, Oleg Chunikhin, CTO at Kublr, answered these questions and demonstrated techniques for implementing advanced scheduling. For example, using spot instances and co...
The use of containers by developers -- and now increasingly IT operators -- has grown from infatuation to deep and abiding love. But as with any long-term affair, the honeymoon soon leads to needing to live well together ... and maybe even getting some relationship help along the way. And so it goes with container orchestration and automation solutions, which are rapidly emerging as the means to maintain the bliss between rapid container adoption and broad container use among multiple cloud host...
The cloud era has reached the stage where it is no longer a question of whether a company should migrate, but when. Enterprises have embraced the outsourcing of where their various applications are stored and who manages them, saving significant investment along the way. Plus, the cloud has become a defining competitive edge. Companies that fail to successfully adapt risk failure. The media, of course, continues to extol the virtues of the cloud, including how easy it is to get there. Migrating...
Imagine if you will, a retail floor so densely packed with sensors that they can pick up the movements of insects scurrying across a store aisle. Or a component of a piece of factory equipment so well-instrumented that its digital twin provides resolution down to the micrometer.