|By PR Newswire||
|January 29, 2014 10:32 AM EST||
LAUSANNE, Switzerland, January 29, 2014 /PRNewswire/ --
The JewelPUMP2, which will be unveiled for the first time at the ATTD 2014 congress on February 5th in Vienna, is a new product dedicated to the Diabetes Type 2 market, based on Debiotech's innovative JewelPUMP platform.
The JewelPUMP2 has been entirely re-designed to address the very specific market of Type 2 patients, requiring an extremely simple to use and very convenient and secured insulin delivery patch.
By using its JewelPUMP platform, which is already in the industrialization phase and in preparation for the CE marking, Debiotech will be able to introduce the JewelPUMP2 shortly after its JewelPUMP for Type 1 patients, while ensuring the same degree of miniaturization, safety and reliability. The JewelPUMP2 is opening entirely new possibilities for Diabetic Type 2 patients, including improved convenience of use, very easy programming with simplified basal-bolus selection and automatic Meal correction, as well as real-time remote communication and assistance to assist in proper treatment compliance.
"The development of a specific patch pump for Type 2 patients was always on our agenda," says Frédéric Neftel, MD, President and CEO of DEBIOTECH SA. "Now that we have completed the development of our JewelPUMP platform, we are in a position to present the JewelPUMP2 that is currently well advanced in our development program to serve that huge additional part of the diabetes market that remains poorly addressed today. The JewelPUMP2 takes all the advantages of the JewelPUMP platform, while addressing very specific needs for Type 2 patients, including extreme simplification of use and convenience, as well as real-time remote communication for the necessary compliance surveillance and patient assistance. We are extremely excited about all the new features we will be able to bring to patients suffering from Type 2 diabetes, while making the treatment very discreet, more comfortable and easier as well as more efficient to use than a pen".
"The Type 2 market represents a huge opportunity for a product like the JewelPUMP2, with a sizable portion of Type 2 patients requiring high doses of insulin that cannot be delivered with existing pumps" says Laurent-Dominique Piveteau, PhD, Chief Operating Officer at DEBIOTECH. "We believe that the JewelPUMP2, with its unique reservoir size and capabilities, very small size and extreme simplicity of use, will make a real difference in that specific market."
"The JewelPUMP2 is not only extremely small and convenient, but also very simple to use thanks to a very novel interface addressing patient concerns using a pump and reducing overall usage complexity," says Stephane Proennecke, PhD, JewelPUMP Project Leader at DEBIOTECH. "With this new miniaturized BGM-remote control device that fits into your pocket, we have been able to make a basal-bolus regimen extremely easy to understand and control. Just enter your meal type (breakfast, lunch or dinner) and the bolus will be automatically administered, as needed. If you want to say that it is an extra-large or particularly slim dinner, user can easily adapt the bolus as needed. If you measure your glucose level with the integrated BGM, the pump will automatically propose a bolus adapted to your needs. The remote controller will also remind you when it is time to measure your Blood Glucose level or if you have forgotten your meal bolus. You can adapt your basal mode according to your exercise or your behavior, with only few intuitive steps using easily understandable icon buttons. Even if you are not familiar with a PDA-phone, you should be able to use the JewelPUMP2. Last but not least, in the presence of others, you can entirely control your JewelPUMP2 without anyone else noticing and the two buttons on the pump will enable you to self-administer a bolus in the absence of your remote controller."
"Despite its very small size and a weight of only 25 grams, the JewelPUMP2 comprises a large reservoir containing up to 800 U of U-100 fast acting insulin for 7 days use. The JewelPUMP2 is secured to an auto-inserted soft-cannula patch, from which it can be detached and re-attached at will, the soft-cannula patch being replaced every 3 days without having to change or refill the pump," says Olivier Magnenat, Head of the JewelPUMP Mechanical Construction group at DEBIOTECH. "The JewelPUMP2 is also equipped with an air filter, so that the insulin filling process is simplified. With the JewelPUMP2 we have been able to address the issue of large insulin consumption, while reducing the constraints of overall size and preparation hurdles."
"Real-time communication through the 3G telephone band is a real must in todays environment to ensure patient compliance and help prevent unexpected situations," says Cristian Arfire, MSc, Head of the Software Engineering team at DEBIOTECH. "With the JewelPUMP2 the patient, but also his authorized doctor and/or diabetes educator, can have immediate access to all relevant treatment information or warning messages received in critical conditions. This could be significantly helpful in those circumstances where treatment compliance or awareness is a concern. Because we are also mindful of the potential for malware in the medical arena, we have put a JewelCARD inside each remote controller (a dedicated smart card specific to each JewelPUMP2), so that we can ensure the most secured environment for remotely controlled medical devices. Overall, the JewelPUMP2 is certainly a jewel of technology, though inconspicuous to the patient."
"We were able to incorporate a vibrator alarm inside the patch-pump, to keep alarms extremely discreet, only to be noticed by the patient himself," says Séverin Leven, PhD, Head of the JewelPUMP Electronic team at DEBIOTECH SA. "We have also been able to make the electronic control module a re-usable part to be attached to the single-use pump-reservoir module. This makes the system more environmentally friendly and helps reduce overall cost. The communication between the JewelPUMP2 and the remote controller is using the new Bluetooth low energy standard and, thanks to its MEMS pump-chip, the JewelPUMP2 can operate for 7 days on a single green battery (mercury and lithium free). We have even incorporated a temperature sensor to inform the patient in case insulin over-exposer to heat.
Last but not least, we have added a sensor to automatically detect any disconnection of the JewelPUMP2 from the cannula patch, allowing automatic suspend of insulin delivery until it is reattached. In short, we have tried to implement everything possible to increase safety and ease-of-use to be part of the JewelPUMP2 experience."
Based on an ultra-miniaturized and highly precise MEMS pump chip technology,
developed and manufactured in partnership with ST Microelectronics, the JewelPUMP is addressing still unmet needs, both in the Type 1 and Type 2 diabetes markets.
"We wanted the JewelPUMP2 to be the easiest, but also the safest insulin pump," says Eric Chappel, PhD, MEMS Project Leader at DEBIOTECH. "The use of a MEMS pump-chip enables to deliver every single 0.02 Units of insulin within 5% accuracy and this independently of external conditions. This represents instantaneous and basal deliveries that are far more constant than any existing system today. In addition, we have incorporated a functional sensor inside the MEMS pump-chip, which provides a signal that is analyzed by the electronics of the JewelPUMP2 and helps detect and discriminate any possible failure almost instantaneously. As an example, the JewelPUMP2 is able to detect an occlusion on the cannula during a basal rate of 0.5U/h within a few minutes, where other pumps would need several hours. The same sensor, which is also used to test every single JewelPUMP2 during production, ensures the delivery to the patient of a fully functional and accurate JewelPUMP2 disposable module, something which has never been possible at this level on disposable medical pumps."
"All this has been made possible thanks to the intensive collaboration between Debiotech and ST Microelectronics" adds Gian-Luca Lettieri, PhD, MEMS Production Leader at DEBIOTECH. "By combining our design with ST's extensive manufacturing experience, we are able to offer a high performance and affordable commercial product".
"The JewelPUMP2 has been tested in every of the worst conditions to ensure that it fulfills all of the safety and performance requirements," says Christophe Conan, PhD, Head of the Testing team. "We are proud to say that the outcome of those tests have exceeded our expectations, thanks to the precision of the MEMS pump technology and the built-in sensor that provides extremely useful real time information. In addition, the comparison with existing insulin pumps on the market has shown that the JewelPUMP2 could bring real significant advantages to safety and accuracy for the patient."
"The JewelPUMP has been successfully used on 35 diabetic patients, as part of a multi-center study in combination with a continuous glucose monitor, for the development of new algorithms for a closed-loop system", says Ary Saaman, Director of Regulatory Affairs at DEBIOTECH. "The purpose is for us to prepare the future and be able to incorporate such newly developed very precise algorithms into a later generation of the JewelPUMP to move diabetes therapy into the closed-loop control era. Knowing how much time will be needed before such a system can be approved for use, it is our responsibility to work on it already from today."
We know how many expectations the JewelPUMP has created. Unfortunately Debiotech cannot give any precise date regarding its market launch at this stage, but is actively engaged in order to submit files to the regulatory agencies, in Europe as well as in the US. Be assured that DEBIOTECH is highly committed to making the JewelPUMP available to all diabetic patients worldwide, with the continuous support of numerous patients, nurses and diabetologists.
More information is available at:
JewelPUMP2[TM] is currently under final stage development. It is not yet CE Marked and has not yet been submitted for 510k clearance.
SOURCE Debiotech SA
More and more companies are looking to microservices as an architectural pattern for breaking apart applications into more manageable pieces so that agile teams can deliver new features quicker and more effectively. What this pattern has done more than anything to date is spark organizational transformations, setting the foundation for future application development. In practice, however, there are a number of considerations to make that go beyond simply “build, ship, and run,” which changes ho...
Feb. 7, 2016 10:45 AM EST Reads: 138
With an estimated 50 billion devices connected to the Internet by 2020, several industries will begin to expand their capabilities for retaining end point data at the edge to better utilize the range of data types and sheer volume of M2M data generated by the Internet of Things. In his session at @ThingsExpo, Don DeLoach, CEO and President of Infobright, will discuss the infrastructures businesses will need to implement to handle this explosion of data by providing specific use cases for filte...
Feb. 7, 2016 10:15 AM EST
SYS-CON Events announced today that AppNeta, the leader in performance insight for business-critical web applications, will exhibit and present at SYS-CON's @DevOpsSummit at Cloud Expo New York, which will take place on June 7-9, 2016, at the Javits Center in New York City, NY. AppNeta is the only application performance monitoring (APM) company to provide solutions for all applications – applications you develop internally, business-critical SaaS applications you use and the networks that deli...
Feb. 7, 2016 10:00 AM EST Reads: 337
SYS-CON Events announced today that Pythian, a global IT services company specializing in helping companies adopt disruptive technologies to optimize revenue-generating systems, has been named “Bronze Sponsor” of SYS-CON's 18th Cloud Expo, which will take place on June 7-9, 2015 at the Javits Center in New York, New York. Founded in 1997, Pythian is a global IT services company that helps companies compete by adopting disruptive technologies such as cloud, Big Data, advanced analytics, and DevO...
Feb. 7, 2016 09:30 AM EST Reads: 137
Advances in technology and ubiquitous connectivity have made the utilization of a dispersed workforce more common. Whether that remote team is located across the street or country, management styles/ approaches will have to be adjusted to accommodate this new dynamic. In his session at 17th Cloud Expo, Sagi Brody, Chief Technology Officer at Webair Internet Development Inc., focused on the challenges of managing remote teams, providing real-world examples that demonstrate what works and what do...
Feb. 7, 2016 09:15 AM EST Reads: 188
As enterprises work to take advantage of Big Data technologies, they frequently become distracted by product-level decisions. In most new Big Data builds this approach is completely counter-productive: it presupposes tools that may not be a fit for development teams, forces IT to take on the burden of evaluating and maintaining unfamiliar technology, and represents a major up-front expense. In his session at @BigDataExpo at @ThingsExpo, Andrew Warfield, CTO and Co-Founder of Coho Data, will dis...
Feb. 7, 2016 07:00 AM EST Reads: 101
SYS-CON Events announced today that Fusion, a leading provider of cloud services, will exhibit at SYS-CON's 18th International Cloud Expo®, which will take place on June 7-9, 2016, at the Javits Center in New York City, NY. Fusion, a leading provider of integrated cloud solutions to small, medium and large businesses, is the industry's single source for the cloud. Fusion's advanced, proprietary cloud service platform enables the integration of leading edge solutions in the cloud, including clou...
Feb. 6, 2016 03:30 PM EST Reads: 709
As someone who has been dedicated to automation and Application Release Automation (ARA) technology for almost six years now, one of the most common questions I get asked regards Platform-as-a-Service (PaaS). Specifically, people want to know whether release automation is still needed when a PaaS is in place, and why. Isn't that what a PaaS provides? A solution to the deployment and runtime challenges of an application? Why would anyone using a PaaS then need an automation engine with workflow ...
Feb. 6, 2016 03:30 PM EST Reads: 106
With the Apple Watch making its way onto wrists all over the world, it’s only a matter of time before it becomes a staple in the workplace. In fact, Forrester reported that 68 percent of technology and business decision-makers characterize wearables as a top priority for 2015. Recognizing their business value early on, FinancialForce.com was the first to bring ERP to wearables, helping streamline communication across front and back office functions. In his session at @ThingsExpo, Kevin Roberts...
Feb. 6, 2016 03:15 PM EST Reads: 328
SYS-CON Events announced today that Commvault, a global leader in enterprise data protection and information management, has been named “Bronze Sponsor” of SYS-CON's 18th International Cloud Expo, which will take place on June 7–9, 2016, at the Javits Center in New York City, NY, and the 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. Commvault is a leading provider of data protection and information management...
Feb. 6, 2016 02:30 PM EST Reads: 355
Your business relies on your applications and your employees to stay in business. Whether you develop apps or manage business critical apps that help fuel your business, what happens when users experience sluggish performance? You and all technical teams across the organization – application, network, operations, among others, as well as, those outside the organization, like ISPs and third-party providers – are called in to solve the problem.
Feb. 6, 2016 02:00 PM EST Reads: 681
SYS-CON Events announced today that Alert Logic, Inc., the leading provider of Security-as-a-Service solutions for the cloud, will exhibit at SYS-CON's 18th International Cloud Expo®, which will take place on June 7-9, 2016, at the Javits Center in New York City, NY. Alert Logic, Inc., provides Security-as-a-Service for on-premises, cloud, and hybrid infrastructures, delivering deep security insight and continuous protection for customers at a lower cost than traditional security solutions. Ful...
Feb. 6, 2016 01:30 PM EST Reads: 345
@DevOpsSummit taking place June 7-9, 2016 at Javits Center, New York City, and Nov 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA, is co-located with the 18th International @CloudExpo and will feature technical sessions from a rock star conference faculty and the leading industry players in the world. @DevOpsSummit at Cloud Expo New York Call for Papers is now open.
Feb. 6, 2016 01:15 PM EST Reads: 514
SYS-CON Events announced today that VAI, a leading ERP software provider, will exhibit at SYS-CON's 18th International Cloud Expo®, which will take place on June 7-9, 2016, at the Javits Center in New York City, NY. VAI (Vormittag Associates, Inc.) is a leading independent mid-market ERP software developer renowned for its flexible solutions and ability to automate critical business functions for the distribution, manufacturing, specialty retail and service sectors. An IBM Premier Business Part...
Feb. 6, 2016 01:00 PM EST Reads: 541
SYS-CON Events announced today that Catchpoint Systems, Inc., a provider of innovative web and infrastructure monitoring solutions, has been named “Silver Sponsor” of SYS-CON's DevOps Summit at 18th Cloud Expo New York, which will take place June 7-9, 2016, at the Javits Center in New York City, NY. Catchpoint is a leading Digital Performance Analytics company that provides unparalleled insight into customer-critical services to help consistently deliver an amazing customer experience. Designed...
Feb. 6, 2016 12:00 PM EST Reads: 322