Welcome!

News Feed Item

Children At Risk For Mercury Poisoning From Dental Fillings, Scientific Journal Reports

CHAMPION'S GATE, Fla., Feb. 5, 2014 /PRNewswire-USNewswire/ -- The following is being released by the International Academy of Oral Medicine and Toxicology (IAOMT):

Dental amalgam may cause mercury poisoning in genetically susceptible children, according to a report published February 1 in the peer-reviewed journal, Biometals. Ironically, this finding arises from several reanalyses of a key clinical trial that is cited by the U.S. Food and Drug Administration (FDA) as evidence for the safety of amalgam. 

The report, entitled, "New science challenges old notion that mercury dental amalgam is safe," identifies several common genetic variants that convey susceptibility to mercury poisoning. The report asserts that mercury vapor from dental amalgam appears to contribute significantly to mercury body burden, and that this exposure appears sufficient to cause harm to susceptible individuals. Finally, the report notes that many Americans with amalgams are exposed to unsafe levels of mercury vapor according to well-established regulatory standards.  

Dental amalgam, the material used for "silver" fillings, contains 50% mercury. Once thought inert, the FDA and the American Dental Association (ADA) now admit that amalgam fillings release mercury vapor. The debate is over whether these levels are harmful.   

The FDA and the ADA base their claims of safety largely on the results of two randomized, controlled, clinical trials on amalgam, which are known as the Children's Amalgam Trials. The initial results, reported in 2006 in the Journal of the American Medical Association, showed no significant difference between the children who received amalgam fillings and those who received resin composite fillings, in terms of group-average measures of brain function. 

Contrary results were observed in 2011 by an independent team that reanalyzed in more detail the longer of the two clinical trials. The investigators divided the amalgam group into high, medium, and low amalgam exposure. This refinement revealed biomarkers of known metabolic harm, called porphyrins, that were associated with higher levels of amalgam. A further reanalysis found that boys who had a common genetic variant, in addition to more exposure to mercury, experienced measurable brain deficits, particularly attention deficit. 

From 2011 to 2013, a total of four separate reanalyses have revealed several measures of biological harm to children in a clinical trial lasting seven years. If left unaddressed for several decades, children will continue to be harmed from exposure to mercury in dental amalgams. According to lead author, Kristin Homme, "We're concerned because mercury appears to be the most biochemically plausible explanation for many mysterious conditions, from developmental disorders to neurodegenerative conditions."  

According to the report, six common genes have been identified that convey susceptibility to mercury, and many more are likely. These findings help explain the amalgam controversy -- why some people seem to be harmed by their mercury fillings, while others appear to be fine, and why amalgam studies have shown inconsistent results, leading authorities to presume the product is safe.  

While the FDA asserts that amalgam illness is anecdotal, dozens of injured consumers have testified at FDA meetings in 2006, 2010, and 2011, yet none have been investigated by the agency. Stacy Case, for example, a telegenic Nashville news anchor who testified in 2011, was diagnosed with Multiple Sclerosis. When she learned that her mercury levels were high, she had her amalgams removed "safely", and after several years her symptoms disappeared.       

In 2010, at the urging of its scientific advisory panel, the FDA agreed to review its amalgam rule based on current science. The agency announced its intention to complete its review by 2011, yet they have been silent ever since.

Contact: Freya Koss, publicist, International Academy of Oral Medicine and Toxicology 
Phone: office- (610) 649-2606, cell- (267) 290-7685

SOURCE International Academy of Oral Medicine and Toxicology

More Stories By PR Newswire

Copyright © 2007 PR Newswire. All rights reserved. Republication or redistribution of PRNewswire content is expressly prohibited without the prior written consent of PRNewswire. PRNewswire shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.

Latest Stories
Without a clear strategy for cost control and an architecture designed with cloud services in mind, costs and operational performance can quickly get out of control. To avoid multiple architectural redesigns requires extensive thought and planning. Boundary (now part of BMC) launched a new public-facing multi-tenant high resolution monitoring service on Amazon AWS two years ago, facing challenges and learning best practices in the early days of the new service. In his session at 19th Cloud Exp...
For basic one-to-one voice or video calling solutions, WebRTC has proven to be a very powerful technology. Although WebRTC’s core functionality is to provide secure, real-time p2p media streaming, leveraging native platform features and server-side components brings up new communication capabilities for web and native mobile applications, allowing for advanced multi-user use cases such as video broadcasting, conferencing, and media recording.
WebRTC is about the data channel as much as about video and audio conferencing. However, basically all commercial WebRTC applications have been built with a focus on audio and video. The handling of “data” has been limited to text chat and file download – all other data sharing seems to end with screensharing. What is holding back a more intensive use of peer-to-peer data? In her session at @ThingsExpo, Dr Silvia Pfeiffer, WebRTC Applications Team Lead at National ICT Australia, looked at differ...
"Plutora provides release and testing environment capabilities to the enterprise," explained Dalibor Siroky, Director and Co-founder of Plutora, in this SYS-CON.tv interview at @DevOpsSummit, held June 9-11, 2015, at the Javits Center in New York City.
With major technology companies and startups seriously embracing IoT strategies, now is the perfect time to attend @ThingsExpo 2016 in New York. Learn what is going on, contribute to the discussions, and ensure that your enterprise is as "IoT-Ready" as it can be! Internet of @ThingsExpo, taking place June 6-8, 2017, at the Javits Center in New York City, New York, is co-located with 20th Cloud Expo and will feature technical sessions from a rock star conference faculty and the leading industry p...
Security, data privacy, reliability and regulatory compliance are critical factors when evaluating whether to move business applications from in-house client hosted environments to a cloud platform. In her session at 18th Cloud Expo, Vandana Viswanathan, Associate Director at Cognizant, In this session, will provide an orientation to the five stages required to implement a cloud hosted solution validation strategy.
SYS-CON Events announced today that CA Technologies has been named "Platinum Sponsor" of SYS-CON's 20th International Cloud Expo®, which will take place on June 6-8, 2017, at the Javits Center in New York City, New York, and 21st International Cloud Expo, which will take place in November in Silicon Valley, California.
The security needs of IoT environments require a strong, proven approach to maintain security, trust and privacy in their ecosystem. Assurance and protection of device identity, secure data encryption and authentication are the key security challenges organizations are trying to address when integrating IoT devices. This holds true for IoT applications in a wide range of industries, for example, healthcare, consumer devices, and manufacturing. In his session at @ThingsExpo, Lancen LaChance, vic...
SYS-CON Events announced today that delaPlex will exhibit at SYS-CON's @CloudExpo, which will take place on June 6-8, 2017, at the Javits Center in New York City, NY. delaPlex pioneered Software Development as a Service (SDaaS), which provides scalable resources to build, test, and deploy software. It’s a fast and more reliable way to develop a new product or expand your in-house team.
Wooed by the promise of faster innovation, lower TCO, and greater agility, businesses of every shape and size have embraced the cloud at every layer of the IT stack – from apps to file sharing to infrastructure. The typical organization currently uses more than a dozen sanctioned cloud apps and will shift more than half of all workloads to the cloud by 2018. Such cloud investments have delivered measurable benefits. But they’ve also resulted in some unintended side-effects: complexity and risk. ...
The explosion of new web/cloud/IoT-based applications and the data they generate are transforming our world right before our eyes. In this rush to adopt these new technologies, organizations are often ignoring fundamental questions concerning who owns the data and failing to ask for permission to conduct invasive surveillance of their customers. Organizations that are not transparent about how their systems gather data telemetry without offering shared data ownership risk product rejection, regu...
More and more brands have jumped on the IoT bandwagon. We have an excess of wearables – activity trackers, smartwatches, smart glasses and sneakers, and more that track seemingly endless datapoints. However, most consumers have no idea what “IoT” means. Creating more wearables that track data shouldn't be the aim of brands; delivering meaningful, tangible relevance to their users should be. We're in a period in which the IoT pendulum is still swinging. Initially, it swung toward "smart for smart...
When you focus on a journey from up-close, you look at your own technical and cultural history and how you changed it for the benefit of the customer. This was our starting point: too many integration issues, 13 SWP days and very long cycles. It was evident that in this fast-paced industry we could no longer afford this reality. We needed something that would take us beyond reducing the development lifecycles, CI and Agile methodologies. We made a fundamental difference, even changed our culture...
The Internet of Things can drive efficiency for airlines and airports. In their session at @ThingsExpo, Shyam Varan Nath, Principal Architect with GE, and Sudip Majumder, senior director of development at Oracle, discussed the technical details of the connected airline baggage and related social media solutions. These IoT applications will enhance travelers' journey experience and drive efficiency for the airlines and the airports.
In his keynote at @ThingsExpo, Chris Matthieu, Director of IoT Engineering at Citrix and co-founder and CTO of Octoblu, focused on building an IoT platform and company. He provided a behind-the-scenes look at Octoblu’s platform, business, and pivots along the way (including the Citrix acquisition of Octoblu).