Welcome!

News Feed Item

Children At Risk For Mercury Poisoning From Dental Fillings, Scientific Journal Reports

CHAMPION'S GATE, Fla., Feb. 5, 2014 /PRNewswire-USNewswire/ -- The following is being released by the International Academy of Oral Medicine and Toxicology (IAOMT):

Dental amalgam may cause mercury poisoning in genetically susceptible children, according to a report published February 1 in the peer-reviewed journal, Biometals. Ironically, this finding arises from several reanalyses of a key clinical trial that is cited by the U.S. Food and Drug Administration (FDA) as evidence for the safety of amalgam. 

The report, entitled, "New science challenges old notion that mercury dental amalgam is safe," identifies several common genetic variants that convey susceptibility to mercury poisoning. The report asserts that mercury vapor from dental amalgam appears to contribute significantly to mercury body burden, and that this exposure appears sufficient to cause harm to susceptible individuals. Finally, the report notes that many Americans with amalgams are exposed to unsafe levels of mercury vapor according to well-established regulatory standards.  

Dental amalgam, the material used for "silver" fillings, contains 50% mercury. Once thought inert, the FDA and the American Dental Association (ADA) now admit that amalgam fillings release mercury vapor. The debate is over whether these levels are harmful.   

The FDA and the ADA base their claims of safety largely on the results of two randomized, controlled, clinical trials on amalgam, which are known as the Children's Amalgam Trials. The initial results, reported in 2006 in the Journal of the American Medical Association, showed no significant difference between the children who received amalgam fillings and those who received resin composite fillings, in terms of group-average measures of brain function. 

Contrary results were observed in 2011 by an independent team that reanalyzed in more detail the longer of the two clinical trials. The investigators divided the amalgam group into high, medium, and low amalgam exposure. This refinement revealed biomarkers of known metabolic harm, called porphyrins, that were associated with higher levels of amalgam. A further reanalysis found that boys who had a common genetic variant, in addition to more exposure to mercury, experienced measurable brain deficits, particularly attention deficit. 

From 2011 to 2013, a total of four separate reanalyses have revealed several measures of biological harm to children in a clinical trial lasting seven years. If left unaddressed for several decades, children will continue to be harmed from exposure to mercury in dental amalgams. According to lead author, Kristin Homme, "We're concerned because mercury appears to be the most biochemically plausible explanation for many mysterious conditions, from developmental disorders to neurodegenerative conditions."  

According to the report, six common genes have been identified that convey susceptibility to mercury, and many more are likely. These findings help explain the amalgam controversy -- why some people seem to be harmed by their mercury fillings, while others appear to be fine, and why amalgam studies have shown inconsistent results, leading authorities to presume the product is safe.  

While the FDA asserts that amalgam illness is anecdotal, dozens of injured consumers have testified at FDA meetings in 2006, 2010, and 2011, yet none have been investigated by the agency. Stacy Case, for example, a telegenic Nashville news anchor who testified in 2011, was diagnosed with Multiple Sclerosis. When she learned that her mercury levels were high, she had her amalgams removed "safely", and after several years her symptoms disappeared.       

In 2010, at the urging of its scientific advisory panel, the FDA agreed to review its amalgam rule based on current science. The agency announced its intention to complete its review by 2011, yet they have been silent ever since.

Contact: Freya Koss, publicist, International Academy of Oral Medicine and Toxicology 
Phone: office- (610) 649-2606, cell- (267) 290-7685

SOURCE International Academy of Oral Medicine and Toxicology

More Stories By PR Newswire

Copyright © 2007 PR Newswire. All rights reserved. Republication or redistribution of PRNewswire content is expressly prohibited without the prior written consent of PRNewswire. PRNewswire shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.

Latest Stories
"Infoblox does DNS, DHCP and IP address management for not only enterprise networks but cloud networks as well. Customers are looking for a single platform that can extend not only in their private enterprise environment but private cloud, public cloud, tracking all the IP space and everything that is going on in that environment," explained Steve Salo, Principal Systems Engineer at Infoblox, in this SYS-CON.tv interview at 21st Cloud Expo, held Oct 31 – Nov 2, 2017, at the Santa Clara Conventio...
"Codigm is based on the cloud and we are here to explore marketing opportunities in America. Our mission is to make an ecosystem of the SW environment that anyone can understand, learn, teach, and develop the SW on the cloud," explained Sung Tae Ryu, CEO of Codigm, in this SYS-CON.tv interview at 21st Cloud Expo, held Oct 31 – Nov 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA.
The question before companies today is not whether to become intelligent, it’s a question of how and how fast. The key is to adopt and deploy an intelligent application strategy while simultaneously preparing to scale that intelligence. In her session at 21st Cloud Expo, Sangeeta Chakraborty, Chief Customer Officer at Ayasdi, provided a tactical framework to become a truly intelligent enterprise, including how to identify the right applications for AI, how to build a Center of Excellence to oper...
"IBM is really all in on blockchain. We take a look at sort of the history of blockchain ledger technologies. It started out with bitcoin, Ethereum, and IBM evaluated these particular blockchain technologies and found they were anonymous and permissionless and that many companies were looking for permissioned blockchain," stated René Bostic, Technical VP of the IBM Cloud Unit in North America, in this SYS-CON.tv interview at 21st Cloud Expo, held Oct 31 – Nov 2, 2017, at the Santa Clara Conventi...
Gemini is Yahoo’s native and search advertising platform. To ensure the quality of a complex distributed system that spans multiple products and components and across various desktop websites and mobile app and web experiences – both Yahoo owned and operated and third-party syndication (supply), with complex interaction with more than a billion users and numerous advertisers globally (demand) – it becomes imperative to automate a set of end-to-end tests 24x7 to detect bugs and regression. In th...
Large industrial manufacturing organizations are adopting the agile principles of cloud software companies. The industrial manufacturing development process has not scaled over time. Now that design CAD teams are geographically distributed, centralizing their work is key. With large multi-gigabyte projects, outdated tools have stifled industrial team agility, time-to-market milestones, and impacted P&L stakeholders.
High-velocity engineering teams are applying not only continuous delivery processes, but also lessons in experimentation from established leaders like Amazon, Netflix, and Facebook. These companies have made experimentation a foundation for their release processes, allowing them to try out major feature releases and redesigns within smaller groups before making them broadly available. In his session at 21st Cloud Expo, Brian Lucas, Senior Staff Engineer at Optimizely, discussed how by using ne...
"Cloud Academy is an enterprise training platform for the cloud, specifically public clouds. We offer guided learning experiences on AWS, Azure, Google Cloud and all the surrounding methodologies and technologies that you need to know and your teams need to know in order to leverage the full benefits of the cloud," explained Alex Brower, VP of Marketing at Cloud Academy, in this SYS-CON.tv interview at 21st Cloud Expo, held Oct 31 – Nov 2, 2017, at the Santa Clara Convention Center in Santa Clar...
Widespread fragmentation is stalling the growth of the IIoT and making it difficult for partners to work together. The number of software platforms, apps, hardware and connectivity standards is creating paralysis among businesses that are afraid of being locked into a solution. EdgeX Foundry is unifying the community around a common IoT edge framework and an ecosystem of interoperable components.
"CA has been doing a lot of things in the area of DevOps. Now we have a complete set of tool sets in order to enable customers to go all the way from planning to development to testing down to release into the operations," explained Aruna Ravichandran, Vice President of Global Marketing and Strategy at CA Technologies, in this SYS-CON.tv interview at DevOps Summit at 21st Cloud Expo, held Oct 31 – Nov 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA.
In his session at 21st Cloud Expo, James Henry, Co-CEO/CTO of Calgary Scientific Inc., introduced you to the challenges, solutions and benefits of training AI systems to solve visual problems with an emphasis on improving AIs with continuous training in the field. He explored applications in several industries and discussed technologies that allow the deployment of advanced visualization solutions to the cloud.
"MobiDev is a software development company and we do complex, custom software development for everybody from entrepreneurs to large enterprises," explained Alan Winters, U.S. Head of Business Development at MobiDev, in this SYS-CON.tv interview at 21st Cloud Expo, held Oct 31 – Nov 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA.
Agile has finally jumped the technology shark, expanding outside the software world. Enterprises are now increasingly adopting Agile practices across their organizations in order to successfully navigate the disruptive waters that threaten to drown them. In our quest for establishing change as a core competency in our organizations, this business-centric notion of Agile is an essential component of Agile Digital Transformation. In the years since the publication of the Agile Manifesto, the conn...
In his session at 21st Cloud Expo, Carl J. Levine, Senior Technical Evangelist for NS1, will objectively discuss how DNS is used to solve Digital Transformation challenges in large SaaS applications, CDNs, AdTech platforms, and other demanding use cases. Carl J. Levine is the Senior Technical Evangelist for NS1. A veteran of the Internet Infrastructure space, he has over a decade of experience with startups, networking protocols and Internet infrastructure, combined with the unique ability to it...
Vulnerability management is vital for large companies that need to secure containers across thousands of hosts, but many struggle to understand how exposed they are when they discover a new high security vulnerability. In his session at 21st Cloud Expo, John Morello, CTO of Twistlock, addressed this pressing concern by introducing the concept of the “Vulnerability Risk Tree API,” which brings all the data together in a simple REST endpoint, allowing companies to easily grasp the severity of the ...