Welcome!

News Feed Item

Brain Research Foundation Announces 2014 Scientific Innovations Awards (SIA) To Fund Groundbreaking Work In Parkinson's, Epilepsy, Hurler Syndrome And Autism

Producing important findings in a short timeframe is the goal of this special grant program

CHICAGO, Feb. 7, 2014 /PRNewswire/ -- Brain Research Foundation (BRF) announced three recipients of its 2014 Scientific Innovations Award program (SIAs) for researchers investigating novel pathways to detect, treat and better comprehend serious neural diseases such as Parkinson's and schizophrenia.

"The innovation that these researchers bring to addressing the scientific understanding and potential treatment of devastating diseases is inspiring," stated Terre A. Constantine, Ph.D., and Executive Director of the Brain Research Foundation. "If this research proves these approaches successful, many areas of neuroscience will benefit."

The SIAs support innovative discovery in both basic and clinical neuroscience. This funding mechanism is designed to support creative, cutting edge research in well-established research laboratories, under the direction of established investigators. Descriptions of the work funded by the 2014 SIAs follow:

A "burst" is a brief period of high-frequency activity within neurons that can have a powerful impact on brain circuits. Symptoms in human diseases like Parkinson's and epilepsy are thought to be influenced by "overly-exuberant" bursting. With his 2014 SIA, Christopher I. Moore, Ph.D., Department of Neuroscience at Brown University, will conduct research to determine if biological strategies can be effective at modulating thalamic bursts. Data gathered may indicate potential for entire new treatment strategies, reducing or eliminating the need for intrusive and painful electrode implants.

Hurler syndrome is a genetic disease that manifests itself after birth through developmental delay, dwarfism, mental retardation and frequently death prior to ten years of age. With a 2014 SIA, W. Mark Saltzman, Ph.D., Department of Biomedical Engineering at Yale University, will attempt to correct the gene disorder in Hurler syndrome in mice by "editing" genes in utero using nanotechnology. The potentially transformative approach, if successful, can be applied to any single gene defect – such as Huntington's disease and Fragile-X syndrome.

Disruptions in neural circuitry cause many diseases such autism and schizophrenia. However, scientists' ability to study brain wiring has been greatly limited. Using a 2014 SIA, Anthony Zador, M.D., Ph.D., Department of Neuroscience, Cold Spring Harbor Laboratory, will test an innovative alternative to mapping neural connectivity. Rather than "take" a picture of brain wiring and connectivity through microscopy, Dr. Zador will "build" a picture or model through a unique DNA sequencing technique. The approach will be used to assess the brain wiring in a mouse model of autism. If successful, this technique can potentially be used to analyze neural circuitry disruptions in a great number of neuropsychiatric disorders.

The SIA Grants are specifically for projects that may be too innovative and speculative for traditional funding sources but still have a high likelihood of producing important findings in a very short timeframe. It is expected that investigations supported by these grants will yield high impact data and result in additional major grant funding and significant publications in key journals.

About the Brain Research Foundation
The Brain Research Foundation (theBRF.org) supports cutting-edge neuroscience research that will lead to novel treatments and prevention of all neurological diseases in children and adults. We deliver this commitment through research grants, which provide initial funding for innovative projects, as well as educational programs for researchers and the general public.

For more information:
BRF contact:
Deborah Schneider
312.280.8702
[email protected]

SOURCE Brain Research Foundation

More Stories By PR Newswire

Copyright © 2007 PR Newswire. All rights reserved. Republication or redistribution of PRNewswire content is expressly prohibited without the prior written consent of PRNewswire. PRNewswire shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.

Latest Stories
SYS-CON Events announced today the Enterprise IoT Bootcamp, being held November 1-2, 2016, in conjunction with 19th Cloud Expo | @ThingsExpo at the Santa Clara Convention Center in Santa Clara, CA. Combined with real-world scenarios and use cases, the Enterprise IoT Bootcamp is not just based on presentations but with hands-on demos and detailed walkthroughs. We will introduce you to a variety of real world use cases prototyped using Arduino, Raspberry Pi, BeagleBone, Spark, and Intel Edison. Y...
Complete Internet of Things (IoT) embedded device security is not just about the device but involves the entire product’s identity, data and control integrity, and services traversing the cloud. A device can no longer be looked at as an island; it is a part of a system. In fact, given the cross-domain interactions enabled by IoT it could be a part of many systems. Also, depending on where the device is deployed, for example, in the office building versus a factory floor or oil field, security ha...
Is your aging software platform suffering from technical debt while the market changes and demands new solutions at a faster clip? It’s a bold move, but you might consider walking away from your core platform and starting fresh. ReadyTalk did exactly that. In his General Session at 19th Cloud Expo, Michael Chambliss, Head of Engineering at ReadyTalk, will discuss why and how ReadyTalk diverted from healthy revenue and over a decade of audio conferencing product development to start an innovati...
Fifty billion connected devices and still no winning protocols standards. HTTP, WebSockets, MQTT, and CoAP seem to be leading in the IoT protocol race at the moment but many more protocols are getting introduced on a regular basis. Each protocol has its pros and cons depending on the nature of the communications. Does there really need to be only one protocol to rule them all? Of course not. In his session at @ThingsExpo, Chris Matthieu, co-founder and CTO of Octoblu, walk you through how Oct...
The Jevons Paradox suggests that when technological advances increase efficiency of a resource, it results in an overall increase in consumption. Writing on the increased use of coal as a result of technological improvements, 19th-century economist William Stanley Jevons found that these improvements led to the development of new ways to utilize coal. In his session at 19th Cloud Expo, Mark Thiele, Chief Strategy Officer for Apcera, will compare the Jevons Paradox to modern-day enterprise IT, e...
SYS-CON Events announced today that Bsquare has been named “Silver Sponsor” of SYS-CON's @ThingsExpo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. For more than two decades, Bsquare has helped its customers extract business value from a broad array of physical assets by making them intelligent, connecting them, and using the data they generate to optimize business processes.
Whether they’re located in a public, private, or hybrid cloud environment, cloud technologies are constantly evolving. While the innovation is exciting, the end mission of delivering business value and rapidly producing incremental product features is paramount. In his session at @DevOpsSummit at 19th Cloud Expo, Kiran Chitturi, CTO Architect at Sungard AS, will discuss DevOps culture, its evolution of frameworks and technologies, and how it is achieving maturity. He will also cover various st...
Identity is in everything and customers are looking to their providers to ensure the security of their identities, transactions and data. With the increased reliance on cloud-based services, service providers must build security and trust into their offerings, adding value to customers and improving the user experience. Making identity, security and privacy easy for customers provides a unique advantage over the competition.
There are several IoTs: the Industrial Internet, Consumer Wearables, Wearables and Healthcare, Supply Chains, and the movement toward Smart Grids, Cities, Regions, and Nations. There are competing communications standards every step of the way, a bewildering array of sensors and devices, and an entire world of competing data analytics platforms. To some this appears to be chaos. In this power panel at @ThingsExpo, moderated by Conference Chair Roger Strukhoff, Bradley Holt, Developer Advocate a...
SYS-CON Events announced today that Niagara Networks will exhibit at the 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. Niagara Networks offers the highest port-density systems, and the most complete Next-Generation Network Visibility systems including Network Packet Brokers, Bypass Switches, and Network TAPs.
SYS-CON Events announced today that Secure Channels will exhibit at the 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. The bedrock of Secure Channels Technology is a uniquely modified and enhanced process based on superencipherment. Superencipherment is the process of encrypting an already encrypted message one or more times, either using the same or a different algorithm.
If you’re responsible for an application that depends on the data or functionality of various IoT endpoints – either sensors or devices – your brand reputation depends on the security, reliability, and compliance of its many integrated parts. If your application fails to deliver the expected business results, your customers and partners won't care if that failure stems from the code you developed or from a component that you integrated. What can you do to ensure that the endpoints work as expect...
So, you bought into the current machine learning craze and went on to collect millions/billions of records from this promising new data source. Now, what do you do with them? Too often, the abundance of data quickly turns into an abundance of problems. How do you extract that "magic essence" from your data without falling into the common pitfalls? In her session at @ThingsExpo, Natalia Ponomareva, Software Engineer at Google, provided tips on how to be successful in large scale machine learning...
If you had a chance to enter on the ground level of the largest e-commerce market in the world – would you? China is the world’s most populated country with the second largest economy and the world’s fastest growing market. It is estimated that by 2018 the Chinese market will be reaching over $30 billion in gaming revenue alone. Admittedly for a foreign company, doing business in China can be challenging. Often changing laws, administrative regulations and the often inscrutable Chinese Interne...
In his general session at 18th Cloud Expo, Lee Atchison, Principal Cloud Architect and Advocate at New Relic, discussed cloud as a ‘better data center’ and how it adds new capacity (faster) and improves application availability (redundancy). The cloud is a ‘Dynamic Tool for Dynamic Apps’ and resource allocation is an integral part of your application architecture, so use only the resources you need and allocate /de-allocate resources on the fly.