|By PR Newswire||
|March 5, 2014 04:00 AM EST||
- Research Supports the Use of Hologic's Lower Dose 3D Mammography Technology and the Continued Use of Two-views Over One in Breast Cancer Screening
BEDFORD, Massachusetts, March 5, 2014 /PRNewswire/ -- Hologic, Inc. (Hologic or the Company) (NASDAQ: HOLX), a leading developer, manufacturer and supplier of premium diagnostic products, medical imaging systems and surgical products, with an emphasis on serving the healthcare needs of women, announced today the publication of three new studies supporting the use of Hologic's award-winning 3D mammography (tomosynthesis) technology in breast cancer screening.
A number of studies have validated the benefits of Hologic's 3D mammography technology in screening: a simultaneous increase in cancer detection rates, for invasive cancers in particular, and a significant reduction in unnecessary patient recalls. Although the benefits of 3D mammography far outweigh the perceived risks, some potential users have expressed concern about the increased dose of a combined conventional 2D and 3D mammography exam. While the radiation dose from the combined 2D and 3D exposure is within the U.S. guidelines for mammography, Hologic now offers customers the low dose C-View software option which generates the 2D image from the 3D mammography image slices thereby eliminating the need for a separate 2D exposure.
Two studies published this month evaluated Hologic's Digital Breast Tomosynthesis using 2D images generated from the 3D mammography slices in place of conventional 2D images – a technique that would reduce the radiation dose of 3D mammography studies to the level of conventional 2D screening and shorten the patient exam time while maintaining all the clinical benefits of 3D. A third study evaluated the use of one-view versus two-view tomosynthesis.
Oslo Study. The results of a four-year prospective trial based on 24,901 screening examinations in a large hospital in Norway, "Two-View Digital Breast Tomosynthesis Screening with Synthetically Reconstructed Projection Images: Comparison with Digital Breast Tomosynthesis with Full-Field Digital Mammographic Images," evaluated the use of 2D images generated from the 3D mammography slices in place of conventional 2D images that are required as part of the Digital Breast Tomosynthesis procedure. Per Skaane, MD, PhD, Department of Radiology, Oslo University Hospital Ullevaal, and his colleagues found that the use of Hologic 3D and generated 2D images constituted an average dose reduction of 45% while not resulting in any clinically meaningful differences in diagnostic accuracy compared to 3D mammography and conventional 2D images. The study was published online in advance of print in the January 24, 2014 issue of Radiology, a scientific journal of the Radiological Society of North America (RSNA).
UPMC Study. A reader study, "Comparison of Two-dimensional Synthesized Mammograms versus Original Digital Mammograms Alone in Combination with Tomosynthesis Images," also looked at whether generated 2D images could be used in place of conventional 2D images in a 3D mammography exam. The authors in this retrospective study compared the results of eight expert readers evaluating a set of cases representing the range of lesions and normal confounders identified in clinical practice. Margarita L. Zuley, MD, Department of Radiology, Magee Women's Hospital, University of Pittsburgh Medical Center, and her colleagues concluded that generated 2D images did not result in any clinically meaningful differences in diagnostic accuracy and could be used to eliminate the need for conventional 2D mammography as part of a routine 3D mammography exam. The study was published online in advance of print in the January 21, 2014 issue of Radiology.
Massachusetts General Hospital Study. A multi-reader study, "Diagnostic Accuracy and Recall Rates for Digital Mammography and Digital Mammography Combined with One-view and Two-view Tomosynthesis: Results of an Enriched Reader Study," found that while the addition of Hologic's one-view 3D mammography to conventional digital mammography significantly improved diagnostic accuracy and reduced the recall rate, the addition of Hologic's two-view 3D mammography provided twice the performance gain in diagnostic accuracy while further reducing unnecessary patient recalls. The researchers concluded that "an approach combining two-view 3D mammography with digital mammography should be the model adopted in clinical practice." In addition, the researchers showed that the addition of two-view 3D mammography provided significantly higher diagnostic accuracy for imaging women with dense breast tissue compared to conventional mammography.
Elizabeth A. Rafferty, MD, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, was lead author of this study that was published in the February 2014 issue of the American Journal of Roentgenology (AJR), the scientific journal of the American Roentgen Ray Society.
"Millions of women across the world have already benefited from Hologic's 3D mammography technology," notes David Harding, Group Senior Vice President and General Manager, Women's Health for Hologic. "These three new studies add to the growing body of research supporting the direction we have taken with this game-changing technology."
"We are glad to see support for our lower dose 3D mammography offering," Harding said. "These studies have demonstrated that Hologic's 3D mammography using generated 2D images results in a clinically superior exam with virtually the same radiation dose as a conventional 2D screening exam. And the research by Dr. Rafferty and her colleagues is the latest in a string of studies concluding that the use of two-views in a 3D mammography screening exam should continue to be the model physicians use in clinical practice."
Hologic pioneered the 3D mammography imaging market with the introduction of its Selenia Dimensions 3D system in countries recognizing the CE mark in 2008 and has placed 3D mammography systems in 59 countries. In 2011 Hologic became the first, and still today the only company to have a U.S. Food and Drug Administration approved 3D mammography system.
About Hologic, Inc.:
Hologic, Inc. is a leading developer, manufacturer and supplier of premium diagnostic products, medical imaging systems and surgical products. The Company operates four core business units focused on breast health, diagnostics, GYN surgical, and skeletal health. With a comprehensive suite of technologies and a robust research and development program, Hologic is committed to improving lives. The Company is headquartered in Massachusetts. For more information, visit www.hologic.com.
Hologic, C-View, Dimensions and Selenia are trademarks and/or registered trademarks of Hologic, Inc., and/or its subsidiaries in the United States and/or other countries.
Forward-Looking Statement Disclaimer:
This News Release may contain forward-looking information that involves risks and uncertainties, including statements about the use of Hologic products. There can be no assurance these products will achieve the benefits described herein and that such benefits will be replicated in any particular manner with respect to an individual patient as the actual effect of the use of the products can only be determined on a case-by-case basis depending on the particular circumstances and patient in question. Hologic expressly disclaims any obligation or undertaking to release publicly any updates or revisions to any such statements presented herein to reflect any change in expectations or any change in events, conditions or circumstances on which any such data or statements are based.
910Telecom exhibited at the 19th International Cloud Expo, which took place at the Santa Clara Convention Center in Santa Clara, CA, in November 2016. Housed in the classic Denver Gas & Electric Building, 910 15th St., 910Telecom is a carrier-neutral telecom hotel located in the heart of Denver. Adjacent to CenturyLink, AT&T, and Denver Main, 910Telecom offers connectivity to all major carriers, Internet service providers, Internet backbones and exchanges.
Feb. 21, 2017 02:45 AM EST Reads: 1,322
Whether you like it or not, DevOps is on track for a remarkable alliance with security. The SEC didn’t approve the merger. And your boss hasn’t heard anything about it. Yet, this unruly triumvirate will soon dominate and deliver DevSecOps faster, cheaper, better, and on an unprecedented scale. In his session at DevOps Summit, Frank Bunger, VP of Customer Success at ScriptRock, discussed how this cathartic moment will propel the DevOps movement from such stuff as dreams are made on to a practic...
Feb. 21, 2017 02:00 AM EST Reads: 4,559
As software becomes more and more complex, we, as software developers, have been splitting up our code into smaller and smaller components. This is also true for the environment in which we run our code: going from bare metal, to VMs to the modern-day Cloud Native world of containers, schedulers and micro services. While we have figured out how to run containerized applications in the cloud using schedulers, we've yet to come up with a good solution to bridge the gap between getting your contain...
Feb. 21, 2017 01:15 AM EST Reads: 3,252
The modern software development landscape consists of best practices and tools that allow teams to deliver software in a near-continuous manner. By adopting a culture of automation, measurement and sharing, the time to ship code has been greatly reduced, allowing for shorter release cycles and quicker feedback from customers and users. Still, with all of these tools and methods, how can teams stay on top of what is taking place across their infrastructure and codebase? Hopping between services a...
Feb. 21, 2017 01:00 AM EST Reads: 6,257
Niagara Networks exhibited at the 19th International Cloud Expo, which took place at the Santa Clara Convention Center in Santa Clara, CA, in November 2016. Niagara Networks offers the highest port-density systems, and the most complete Next-Generation Network Visibility systems including Network Packet Brokers, Bypass Switches, and Network TAPs.
Feb. 21, 2017 12:30 AM EST Reads: 702
Zerto exhibited at SYS-CON's 18th International Cloud Expo®, which took place at the Javits Center in New York City, NY, in June 2016. Zerto is committed to keeping enterprise and cloud IT running 24/7 by providing innovative, simple, reliable and scalable business continuity software solutions. Through the Zerto Cloud Continuity Platform™, organizations can seamlessly move and protect virtualized workloads between public, private and hybrid clouds. The company’s flagship product, Zerto Virtual...
Feb. 21, 2017 12:30 AM EST Reads: 1,030
Without a clear strategy for cost control and an architecture designed with cloud services in mind, costs and operational performance can quickly get out of control. To avoid multiple architectural redesigns requires extensive thought and planning. Boundary (now part of BMC) launched a new public-facing multi-tenant high resolution monitoring service on Amazon AWS two years ago, facing challenges and learning best practices in the early days of the new service. In his session at 19th Cloud Exp...
Feb. 20, 2017 10:15 PM EST Reads: 3,329
For basic one-to-one voice or video calling solutions, WebRTC has proven to be a very powerful technology. Although WebRTC’s core functionality is to provide secure, real-time p2p media streaming, leveraging native platform features and server-side components brings up new communication capabilities for web and native mobile applications, allowing for advanced multi-user use cases such as video broadcasting, conferencing, and media recording.
Feb. 20, 2017 10:15 PM EST Reads: 5,915
WebRTC is about the data channel as much as about video and audio conferencing. However, basically all commercial WebRTC applications have been built with a focus on audio and video. The handling of “data” has been limited to text chat and file download – all other data sharing seems to end with screensharing. What is holding back a more intensive use of peer-to-peer data? In her session at @ThingsExpo, Dr Silvia Pfeiffer, WebRTC Applications Team Lead at National ICT Australia, looked at differ...
Feb. 20, 2017 10:15 PM EST Reads: 6,193
"Plutora provides release and testing environment capabilities to the enterprise," explained Dalibor Siroky, Director and Co-founder of Plutora, in this SYS-CON.tv interview at @DevOpsSummit, held June 9-11, 2015, at the Javits Center in New York City.
Feb. 20, 2017 09:15 PM EST Reads: 4,506
With major technology companies and startups seriously embracing IoT strategies, now is the perfect time to attend @ThingsExpo 2016 in New York. Learn what is going on, contribute to the discussions, and ensure that your enterprise is as "IoT-Ready" as it can be! Internet of @ThingsExpo, taking place June 6-8, 2017, at the Javits Center in New York City, New York, is co-located with 20th Cloud Expo and will feature technical sessions from a rock star conference faculty and the leading industry p...
Feb. 20, 2017 09:15 PM EST Reads: 905
Security, data privacy, reliability and regulatory compliance are critical factors when evaluating whether to move business applications from in-house client hosted environments to a cloud platform. In her session at 18th Cloud Expo, Vandana Viswanathan, Associate Director at Cognizant, In this session, will provide an orientation to the five stages required to implement a cloud hosted solution validation strategy.
Feb. 20, 2017 08:45 PM EST Reads: 4,335
SYS-CON Events announced today that CA Technologies has been named "Platinum Sponsor" of SYS-CON's 20th International Cloud Expo®, which will take place on June 6-8, 2017, at the Javits Center in New York City, New York, and 21st International Cloud Expo, which will take place in November in Silicon Valley, California.
Feb. 20, 2017 08:30 PM EST Reads: 1,514
The security needs of IoT environments require a strong, proven approach to maintain security, trust and privacy in their ecosystem. Assurance and protection of device identity, secure data encryption and authentication are the key security challenges organizations are trying to address when integrating IoT devices. This holds true for IoT applications in a wide range of industries, for example, healthcare, consumer devices, and manufacturing. In his session at @ThingsExpo, Lancen LaChance, vic...
Feb. 20, 2017 07:00 PM EST Reads: 8,234
SYS-CON Events announced today that delaPlex will exhibit at SYS-CON's @CloudExpo, which will take place on June 6-8, 2017, at the Javits Center in New York City, NY. delaPlex pioneered Software Development as a Service (SDaaS), which provides scalable resources to build, test, and deploy software. It’s a fast and more reliable way to develop a new product or expand your in-house team.
Feb. 20, 2017 06:15 PM EST Reads: 1,004