News Feed Item

ALS Association and Packard Center Announce the First Scientific Grant Award from the Winokur Family Research Initiative

BALTIMORE, Md., March 10, 2014 /PRNewswire-USNewswire/ -- With the opening of the 14th Annual Robert Packard Center for ALS Research Symposium, the Packard Center and The ALS Association are pleased to announce the first scientific grant award from the Winokur Family Research Initiative. The inaugural grant will help to fund a project under the direction on Phil Wong, Ph.D., a Professor of Pathology at Johns Hopkins University and Liam Chen, M.D., Ph.D., Assistant Professor of Pathology at Johns Hopkins University.  The study will focus on the use of animal models of TDP-43-linked ALS-FTD (frontotemporal dementia) to validate and characterize newly identified therapeutic targets for ALS. 

ALS Logo

ALS (amyotrophic lateral sclerosis), otherwise known as Lou Gehrig's Disease, is a progressive neurodegenerative disease that affects neurons (nerve cells) in the brain and the spinal cord. Eventually, people with ALS lose the ability to initiate and control muscle movement, which often leads to total paralysis and death within two to five years of diagnosis. There is no cure and no life-prolonging treatments for the disease. 

This study is important because it will help identify the valid targets needed for developing effective therapies for ALS. The targets identified by Drs. Wong and Chen will yield a clear understanding of how TDP-43 kills neurons that will identify and develop mechanism-based therapeutics. Previous studies have shown that TPD-43 proteinopathy, which involves malformed proteins, is common in both sporadic and familial ALS and FTD.

"The Packard Center is pleased to have the opportunity to, once again, partner with The ALS Association to work on this important project. We thank our friend Diane Winokur for her support of the work we do to combat ALS and are pleased to honor her and this initiative at the onset of our Annual Scientific Symposium," said Piera Pasinelli, Ph.D., the Packard Center's Science Director.

The Winokur Family Research Initiative was conceived and initiated specifically to fund promising early-stage research by The Association's Golden West Chapter. Through a unique collaboration between the Packard Center and The ALS Association, groundbreaking, targeted studies are supported by a peer-reviewed process that is results-oriented and highly accountable.  The goal is to fund promising early-stage ALS research and move it forward more quickly. Besides providing needed funding for the organizations' ongoing commitment to ALS research, the Winokur Family Research Initiative will also encourage scientists to work together toward the ultimate goal of one day finding a treatment or cure for ALS.

Diane Winokur, founder of the Winokur Family Research Initiative, is a highly-respected leader in the fight against ALS. She, and her late husband, Bob, had first-hand knowledge of how devastating ALS is, having lost two sons, Douglas and Hugh, to the disease.  Winokur serves on the boards of the Golden West Chapter and The Robert Packard Center for ALS Research and was recently appointed as the ALS and MS representative on the Independent Citizen's Oversight Committee, the governing body of the California Institute for Regenerative Medicine (CIRM).

"The ALS Association is delighted to honor Diane Winokur and partner with The Packard Center for ALS Research on this exciting project," said Lucie Bruijn, Ph.D. MBA, Chief Scientist of The ALS Association.

The Packard Center's Research Symposium is an annual meeting, held in Baltimore, Md., that brings together 145 clinicians and bench researchers, postdoctoral students, and advisory board members – all leaders in the field of ALS.  This invitation-only event requires Packard-funded researchers to present their research findings that are subject to peer-reviews by the Center's Board of Scientific Advisors. The Symposium is a review of all research projects funded by the Packard Center, plus a series of updates from clinical partners at the Northeast ALS Consortium (NEALS).  Attendees come from institutions in 21 states across the U.S., as well as from Canada, Belgium, Germany, France, Switzerland, and the United Kingdom.

About the Robert Packard Center for ALS Research
The Robert Packard Center for ALS Research at Johns Hopkins is the only international scientific operation dedicated solely to curing the disease. We are unique in our approach to fighting ALS, a motor neuron disease also known as Lou Gehrig's Disease, in that we combine and facilitate scientific collaboration and ALS research with fundraising for the development of new treatments and to finding a cure. For more information about the Center, visit http://www.alscenter.org/.

About The ALS Association
The ALS Association is the only national non-profit organization fighting Lou Gehrig's Disease on every front.  By leading the way in global research, providing assistance for people with ALS through a nationwide network of chapters, coordinating multidisciplinary care through certified clinical care centers, and fostering government partnerships, The Association builds hope and enhances quality of life while aggressively searching for new treatments and a cure.  For more information about The ALS Association, visit our website at www.alsa.org.

Logo - http://photos.prnewswire.com/prnh/20131211/MM32178LOGO

SOURCE The ALS Association

More Stories By PR Newswire

Copyright © 2007 PR Newswire. All rights reserved. Republication or redistribution of PRNewswire content is expressly prohibited without the prior written consent of PRNewswire. PRNewswire shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.

Latest Stories
DevOpsSummit New York 2018, colocated with CloudEXPO | DXWorldEXPO New York 2018 will be held November 11-13, 2018, in New York City. Digital Transformation (DX) is a major focus with the introduction of DXWorldEXPO within the program. Successful transformation requires a laser focus on being data-driven and on using all the tools available that enable transformation if they plan to survive over the long term. A total of 88% of Fortune 500 companies from a generation ago are now out of bus...
DXWordEXPO New York 2018, colocated with CloudEXPO New York 2018 will be held November 11-13, 2018, in New York City and will bring together Cloud Computing, FinTech and Blockchain, Digital Transformation, Big Data, Internet of Things, DevOps, AI, Machine Learning and WebRTC to one location.
Cloud Expo | DXWorld Expo have announced the conference tracks for Cloud Expo 2018. Cloud Expo will be held June 5-7, 2018, at the Javits Center in New York City, and November 6-8, 2018, at the Santa Clara Convention Center, Santa Clara, CA. Digital Transformation (DX) is a major focus with the introduction of DX Expo within the program. Successful transformation requires a laser focus on being data-driven and on using all the tools available that enable transformation if they plan to survive ov...
DXWorldEXPO LLC announced today that ICOHOLDER named "Media Sponsor" of Miami Blockchain Event by FinTechEXPO. ICOHOLDER give you detailed information and help the community to invest in the trusty projects. Miami Blockchain Event by FinTechEXPO has opened its Call for Papers. The two-day event will present 20 top Blockchain experts. All speaking inquiries which covers the following information can be submitted by email to [email protected] Miami Blockchain Event by FinTechEXPO also offers s...
DXWorldEXPO | CloudEXPO are the world's most influential, independent events where Cloud Computing was coined and where technology buyers and vendors meet to experience and discuss the big picture of Digital Transformation and all of the strategies, tactics, and tools they need to realize their goals. Sponsors of DXWorldEXPO | CloudEXPO benefit from unmatched branding, profile building and lead generation opportunities.
Dion Hinchcliffe is an internationally recognized digital expert, bestselling book author, frequent keynote speaker, analyst, futurist, and transformation expert based in Washington, DC. He is currently Chief Strategy Officer at the industry-leading digital strategy and online community solutions firm, 7Summits.
@DevOpsSummit New York 2018, colocated with CloudEXPO | DXWorldEXPO New York 2018 will be held November 11-13, 2018, in New York City. From showcase success stories from early adopters and web-scale businesses, DevOps is expanding to organizations of all sizes, including the world's largest enterprises - and delivering real results.
The dynamic nature of the cloud means that change is a constant when it comes to modern cloud-based infrastructure. Delivering modern applications to end users, therefore, is a constantly shifting challenge. Delivery automation helps IT Ops teams ensure that apps are providing an optimal end user experience over hybrid-cloud and multi-cloud environments, no matter what the current state of the infrastructure is. To employ a delivery automation strategy that reflects your business rules, making r...
DXWorldEXPO LLC announced today that Dez Blanchfield joined the faculty of CloudEXPO's "10-Year Anniversary Event" which will take place on November 11-13, 2018 in New York City. Dez is a strategic leader in business and digital transformation with 25 years of experience in the IT and telecommunications industries developing strategies and implementing business initiatives. He has a breadth of expertise spanning technologies such as cloud computing, big data and analytics, cognitive computing, m...
Digital Transformation and Disruption, Amazon Style - What You Can Learn. Chris Kocher is a co-founder of Grey Heron, a management and strategic marketing consulting firm. He has 25+ years in both strategic and hands-on operating experience helping executives and investors build revenues and shareholder value. He has consulted with over 130 companies on innovating with new business models, product strategies and monetization. Chris has held management positions at HP and Symantec in addition to ...
DXWorldEXPO LLC announced today that Kevin Jackson joined the faculty of CloudEXPO's "10-Year Anniversary Event" which will take place on November 11-13, 2018 in New York City. Kevin L. Jackson is a globally recognized cloud computing expert and Founder/Author of the award winning "Cloud Musings" blog. Mr. Jackson has also been recognized as a "Top 100 Cybersecurity Influencer and Brand" by Onalytica (2015), a Huffington Post "Top 100 Cloud Computing Experts on Twitter" (2013) and a "Top 50 C...
Cloud-enabled transformation has evolved from cost saving measure to business innovation strategy -- one that combines the cloud with cognitive capabilities to drive market disruption. Learn how you can achieve the insight and agility you need to gain a competitive advantage. Industry-acclaimed CTO and cloud expert, Shankar Kalyana presents. Only the most exceptional IBMers are appointed with the rare distinction of IBM Fellow, the highest technical honor in the company. Shankar has also receive...
Enterprises have taken advantage of IoT to achieve important revenue and cost advantages. What is less apparent is how incumbent enterprises operating at scale have, following success with IoT, built analytic, operations management and software development capabilities - ranging from autonomous vehicles to manageable robotics installations. They have embraced these capabilities as if they were Silicon Valley startups.
Digital transformation is about embracing digital technologies into a company's culture to better connect with its customers, automate processes, create better tools, enter new markets, etc. Such a transformation requires continuous orchestration across teams and an environment based on open collaboration and daily experiments. In his session at 21st Cloud Expo, Alex Casalboni, Technical (Cloud) Evangelist at Cloud Academy, explored and discussed the most urgent unsolved challenges to achieve fu...
Poor data quality and analytics drive down business value. In fact, Gartner estimated that the average financial impact of poor data quality on organizations is $9.7 million per year. But bad data is much more than a cost center. By eroding trust in information, analytics and the business decisions based on these, it is a serious impediment to digital transformation.