Welcome!

News Feed Item

ALS Association and Packard Center Announce the First Scientific Grant Award from the Winokur Family Research Initiative

BALTIMORE, Md., March 10, 2014 /PRNewswire-USNewswire/ -- With the opening of the 14th Annual Robert Packard Center for ALS Research Symposium, the Packard Center and The ALS Association are pleased to announce the first scientific grant award from the Winokur Family Research Initiative. The inaugural grant will help to fund a project under the direction on Phil Wong, Ph.D., a Professor of Pathology at Johns Hopkins University and Liam Chen, M.D., Ph.D., Assistant Professor of Pathology at Johns Hopkins University.  The study will focus on the use of animal models of TDP-43-linked ALS-FTD (frontotemporal dementia) to validate and characterize newly identified therapeutic targets for ALS. 

ALS Logo

ALS (amyotrophic lateral sclerosis), otherwise known as Lou Gehrig's Disease, is a progressive neurodegenerative disease that affects neurons (nerve cells) in the brain and the spinal cord. Eventually, people with ALS lose the ability to initiate and control muscle movement, which often leads to total paralysis and death within two to five years of diagnosis. There is no cure and no life-prolonging treatments for the disease. 

This study is important because it will help identify the valid targets needed for developing effective therapies for ALS. The targets identified by Drs. Wong and Chen will yield a clear understanding of how TDP-43 kills neurons that will identify and develop mechanism-based therapeutics. Previous studies have shown that TPD-43 proteinopathy, which involves malformed proteins, is common in both sporadic and familial ALS and FTD.

"The Packard Center is pleased to have the opportunity to, once again, partner with The ALS Association to work on this important project. We thank our friend Diane Winokur for her support of the work we do to combat ALS and are pleased to honor her and this initiative at the onset of our Annual Scientific Symposium," said Piera Pasinelli, Ph.D., the Packard Center's Science Director.

The Winokur Family Research Initiative was conceived and initiated specifically to fund promising early-stage research by The Association's Golden West Chapter. Through a unique collaboration between the Packard Center and The ALS Association, groundbreaking, targeted studies are supported by a peer-reviewed process that is results-oriented and highly accountable.  The goal is to fund promising early-stage ALS research and move it forward more quickly. Besides providing needed funding for the organizations' ongoing commitment to ALS research, the Winokur Family Research Initiative will also encourage scientists to work together toward the ultimate goal of one day finding a treatment or cure for ALS.

Diane Winokur, founder of the Winokur Family Research Initiative, is a highly-respected leader in the fight against ALS. She, and her late husband, Bob, had first-hand knowledge of how devastating ALS is, having lost two sons, Douglas and Hugh, to the disease.  Winokur serves on the boards of the Golden West Chapter and The Robert Packard Center for ALS Research and was recently appointed as the ALS and MS representative on the Independent Citizen's Oversight Committee, the governing body of the California Institute for Regenerative Medicine (CIRM).

"The ALS Association is delighted to honor Diane Winokur and partner with The Packard Center for ALS Research on this exciting project," said Lucie Bruijn, Ph.D. MBA, Chief Scientist of The ALS Association.

The Packard Center's Research Symposium is an annual meeting, held in Baltimore, Md., that brings together 145 clinicians and bench researchers, postdoctoral students, and advisory board members – all leaders in the field of ALS.  This invitation-only event requires Packard-funded researchers to present their research findings that are subject to peer-reviews by the Center's Board of Scientific Advisors. The Symposium is a review of all research projects funded by the Packard Center, plus a series of updates from clinical partners at the Northeast ALS Consortium (NEALS).  Attendees come from institutions in 21 states across the U.S., as well as from Canada, Belgium, Germany, France, Switzerland, and the United Kingdom.

About the Robert Packard Center for ALS Research
The Robert Packard Center for ALS Research at Johns Hopkins is the only international scientific operation dedicated solely to curing the disease. We are unique in our approach to fighting ALS, a motor neuron disease also known as Lou Gehrig's Disease, in that we combine and facilitate scientific collaboration and ALS research with fundraising for the development of new treatments and to finding a cure. For more information about the Center, visit http://www.alscenter.org/.

About The ALS Association
The ALS Association is the only national non-profit organization fighting Lou Gehrig's Disease on every front.  By leading the way in global research, providing assistance for people with ALS through a nationwide network of chapters, coordinating multidisciplinary care through certified clinical care centers, and fostering government partnerships, The Association builds hope and enhances quality of life while aggressively searching for new treatments and a cure.  For more information about The ALS Association, visit our website at www.alsa.org.

Logo - http://photos.prnewswire.com/prnh/20131211/MM32178LOGO

SOURCE The ALS Association

More Stories By PR Newswire

Copyright © 2007 PR Newswire. All rights reserved. Republication or redistribution of PRNewswire content is expressly prohibited without the prior written consent of PRNewswire. PRNewswire shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.

Latest Stories
SYS-CON Events announced today that Venafi, the Immune System for the Internet™ and the leading provider of Next Generation Trust Protection, will exhibit at @DevOpsSummit at 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. Venafi is the Immune System for the Internet™ that protects the foundation of all cybersecurity – cryptographic keys and digital certificates – so they can’t be misused by bad guys in attacks...
The cloud market growth today is largely in public clouds. While there is a lot of spend in IT departments in virtualization, these aren’t yet translating into a true “cloud” experience within the enterprise. What is stopping the growth of the “private cloud” market? In his general session at 18th Cloud Expo, Nara Rajagopalan, CEO of Accelerite, explored the challenges in deploying, managing, and getting adoption for a private cloud within an enterprise. What are the key differences between wh...
For basic one-to-one voice or video calling solutions, WebRTC has proven to be a very powerful technology. Although WebRTC’s core functionality is to provide secure, real-time p2p media streaming, leveraging native platform features and server-side components brings up new communication capabilities for web and native mobile applications, allowing for advanced multi-user use cases such as video broadcasting, conferencing, and media recording.
In his session at Cloud Expo, Robert Cohen, an economist and senior fellow at the Economic Strategy Institute, will provide economic scenarios that describe how the rapid adoption of software-defined everything including cloud services, SDDC and open networking will change GDP, industry growth, productivity and jobs. This session will also include a drill down for several industries such as finance, social media, cloud service providers and pharmaceuticals.
Security, data privacy, reliability, and regulatory compliance are critical factors when evaluating whether to move business applications from in-house, client-hosted environments to a cloud platform. Quality assurance plays a vital role in ensuring that the appropriate level of risk assessment, verification, and validation takes place to ensure business continuity during the migration to a new cloud platform.
SYS-CON Events announced today the Kubernetes and Google Container Engine Workshop, being held November 3, 2016, in conjunction with @DevOpsSummit at 19th Cloud Expo at the Santa Clara Convention Center in Santa Clara, CA. This workshop led by Sebastian Scheele introduces participants to Kubernetes and Google Container Engine (GKE). Through a combination of instructor-led presentations, demonstrations, and hands-on labs, students learn the key concepts and practices for deploying and maintainin...
Aspose.Total for .NET is the most complete package of all file format APIs for .NET as offered by Aspose. It empowers developers to create, edit, render, print and convert between a wide range of popular document formats within any .NET, C#, ASP.NET and VB.NET applications. Aspose compiles all .NET APIs on a daily basis to ensure that it contains the most up to date versions of each of Aspose .NET APIs. If a new .NET API or a new version of existing APIs is released during the subscription peri...
StackIQ has announced the release of Stacki 3.2. Stacki is an easy-to-use Linux server provisioning tool. Stacki 3.2 delivers new capabilities that simplify the automation and integration of site-specific requirements. StackIQ is the commercial entity behind this open source bare metal provisioning tool. Since the release of Stacki in June of 2015, the Stacki core team has been focused on making the Community Edition meet the needs of members of the community, adding features and value, while ...
There will be new vendors providing applications, middleware, and connected devices to support the thriving IoT ecosystem. This essentially means that electronic device manufacturers will also be in the software business. Many will be new to building embedded software or robust software. This creates an increased importance on software quality, particularly within the Industrial Internet of Things where business-critical applications are becoming dependent on products controlled by software. Qua...
In addition to all the benefits, IoT is also bringing new kind of customer experience challenges - cars that unlock themselves, thermostats turning houses into saunas and baby video monitors broadcasting over the internet. This list can only increase because while IoT services should be intuitive and simple to use, the delivery ecosystem is a myriad of potential problems as IoT explodes complexity. So finding a performance issue is like finding the proverbial needle in the haystack.
"We host and fully manage cloud data services, whether we store, the data, move the data, or run analytics on the data," stated Kamal Shannak, Senior Development Manager, Cloud Data Services, IBM, in this SYS-CON.tv interview at 18th Cloud Expo, held June 7-9, 2016, at the Javits Center in New York City, NY.
DevOps at Cloud Expo – being held November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA – announces that its Call for Papers is open. Born out of proven success in agile development, cloud computing, and process automation, DevOps is a macro trend you cannot afford to miss. From showcase success stories from early adopters and web-scale businesses, DevOps is expanding to organizations of all sizes, including the world's largest enterprises – and delivering real results. Am...
Machine Learning helps make complex systems more efficient. By applying advanced Machine Learning techniques such as Cognitive Fingerprinting, wind project operators can utilize these tools to learn from collected data, detect regular patterns, and optimize their own operations. In his session at 18th Cloud Expo, Stuart Gillen, Director of Business Development at SparkCognition, discussed how research has demonstrated the value of Machine Learning in delivering next generation analytics to imp...
With the proliferation of both SQL and NoSQL databases, organizations can now target specific fit-for-purpose database tools for their different application needs regarding scalability, ease of use, ACID support, etc. Platform as a Service offerings make this even easier now, enabling developers to roll out their own database infrastructure in minutes with minimal management overhead. However, this same amount of flexibility also comes with the challenges of picking the right tool, on the right ...
The 19th International Cloud Expo has announced that its Call for Papers is open. Cloud Expo, to be held November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA, brings together Cloud Computing, Big Data, Internet of Things, DevOps, Digital Transformation, Microservices and WebRTC to one location. With cloud computing driving a higher percentage of enterprise IT budgets every year, it becomes increasingly important to plant your flag in this fast-expanding business opportuni...