News Feed Item

Breakthroughs in Ophthalmic Devices and Drug Delivery Technologies (Technical Insights)

LONDON, March 11, 2014 /PRNewswire/ -- Reportbuyer.com just published a new market research report:

Breakthroughs in Ophthalmic Devices and Drug Delivery Technologies (Technical Insights)

Venture Capital and Private Equity Firms Vital for Ophthalmic Device and Drug Delivery Innovation

The aging of the population around the world will consequently lead to a rapid increase in the 65-and-over population by 2030, a population that accounts for the highest incidence and prevalence of eye conditions and diseases. This sets the stage for increased research and development activities, speedy market approvals, and higher awareness through education. The industry has been dominated by a few big players, however there are many small players/startups who have interesting ideas. This Research Service is focused on the shift in technologies and materials, regulatory platform, IP strength and funding scenario prevalent in the stent industry.

Scope of Research

This research service (RS) is a study on the funding prospects in the ophthalmic device and drug delivery technologies. The aging of the population around the world will consequently lead to a rapid increase in the 65-and-over population by 2030, a population that accounts for the highest incidence and prevalence of eye conditions and diseases. This sets the stage for increased research and development activities, speedy market approvals, and higher awareness through education. The industry has been dominated by a few big players, however there are many small players/startups who have interesting ideas. This RS is focused on the shift in technologies and materials, regulatory platform, IP strength and funding scenario prevalent in the stent industry.

This research service will cover the following key sections in the ophthalmic devices and drug delivery industry:
• Technology trends evidenced in the industry
• Governmental grants and stimulus funding
• Investor networks and recent investment climate
• Key investors, investments, and technology partners
• Assessment of Funding sources
• Smart scouting and procurement strategies for developers

Research Methodology

Primary Research
• Engineers
• CTOs/ CEOs/ CIOs
• Technical Architects
• Research Heads
• Strategic Decision Makers
• Technology Policy Heads

Secondary Research
• Technology Journals
• Periodicals
• Market Research Reports
• Technology policy information sites
• Internal databases
• Thought Leader Briefings

Step 1: To provide a thorough analysis of each topic, Technical Insights' analysts perform a review of patents to become familiar with the major developers and commercial participants and their processes.
Step 2: Building on the patent search, the analysts review abstracts to identify key scientific and technical papers that provide insights into key industry participants and the technical processes, on which they work.
Step 3: The analysts then create a detailed questionnaire with content created to address the research objectives of the study, which functions as a guide during the interview process. While the analysts use structured questionnaires to guarantee coverage of all the desired issues, they also conduct interviews in a conversational style. This approach results in a more thorough exchange of views with the respondents, and offers greater insight into the relevant issues than more structured interviews may provide.

Step 4: The analysts conduct primary research with key industry participants and technology developers to obtain the required content. Interviews are completed with sources located throughout the world, in universities, national laboratories, governmental and regulatory bodies, trade associations, and end-user companies, among other key organizations. Our analysts contact the major commercial participants to find out about the advantages and disadvantages of processes and the drivers and challenges behind technologies and applications. Our analysts talk to the principal developers, researchers, engineers, business developers, analysts, strategic planners, and marketing experts, among other professionals.
Step 5: The project management and research team reviews and analyzes the research data that are gathered and adds its recommendations to the draft of the final study. Having conducted both published studies and custom proprietary research covering many types of new and emerging technology activities as well as worldwide industry analysis, the management and research team adds its perspective and experience to provide an accurate, timely analysis. The analysts then prepare written final research services for each project and sometimes present key findings in analyst briefings to clients.

Key Findings

1. The aging of the population around the world is rapidly increasing the 65-and-over population, a population that accounts for the highest incidence and prevalence of eye conditions and disorders. This sets the stage for increased research and development activities in the field of ophthalmic devices, speedy market approvals, and higher awareness through education. The industry is likely to experience a burst of new products and heavy competition amongst key players.
2. There are 5 major stakeholders in the ophthalmic device and drug delivery segment: research centers , pharmaceutical players, medical imaging players, patients and doctors as end-users and the regulatory authorities. There is a need for collaboration between the various stakeholders. Strategic and business partnerships, scientific and clinical education and a number of confidence building measures have to be developed to win the trust of regulatory authorities, investors and end-users.
3. Private equity investors, venture capitals and VC division of corporate companies are the major financial contributors. Private equity and venture capital funding are playing a key role in technology innovation in this segment. The current in towards developing technologies which focus on treating age related disorders. Technology incubators also play a significant role in this field as many there have been quite a few spin-offs from such incubators.
4. By promoting creativity among physicians and high potential technology advances by small device companies, transformative innovation will definitely see rapid progress. Initiative should be taken to address funding for investigator-directed research and enhanced seed funding from government backed and VC sources to develop small private businesses based on these ideas.

Background - Ophthalmic Disorders

Refractive Disorders
A normal human eye creates a clear and distinct visual image because the cornea and lens bend or refract the incident light rays and focuses them on the retina. The shape of the cornea remains fixed, but the lens changes its shape to suitably alter the focal length and hence focus objects at various distances and perspectives. In refractive disorders, an error occurs when the cornea and lens cannot focus the image of an object sharply on the retina. Because of this, defects in vision are caused. They can either be short-sightedness (myopia), long-sightedness (hyperopia), presbyopia or astigmatism.

Myopia, Hyperopia and Astigmatism
Myopia/near-sightedness arises when the eyeball may be too large for the optical power of the focusing system. Hence, the light rays are focused in front of the retina, rather than directly on it. The patient thus, cannot see distant objects clearly. Alternatively in long-sightedness or hyperopia, the eyeball can become too small for the optical power of the focusing system, and hence the light rays are focused behind the retina. An imperfectly shaped cornea causes objects to appear blurred from any distance or from the sides. This leads to a condition called astigmatism. With increasing age, the lens becomes stiffer; it does not change shape easily, hence it cannot focus on nearby objects, resulting in a condition called presbyopia.

Retinal Disorders
Usually the cornea and lens focus light on the retina, which is found on the interior surface of the back of the eye. Macula is the central region of the retina and is primarily consisted of high density of colour-sensitive photoreceptor cells. Among the older people, age-related macular degeneration causes damage to the macula resulting in gradual loss of vision. In older people, premacular formation occurs over the retina which interferes with vision. Likewise, when the retina detaches, it separates from part of its blood supply, that prevents it from functioning properly for which retinal detachment is the term used. Another rare, progressive degeneration of the retina that eventually causes blindness is often inherited and called retinitis pigmentosa.

Optic Nerve Disorders
Small photoreceptors in the inner eye sense light and transmit impulses to the optic nerve. This nerve carries impulses to the brain. A common cause of damage to the optic nerve arises from a tumour of the pituitary gland that presses on the nerve. Papilledema is a rare condition in which increased pressure in or around the brain causes the optic nerve to swell intensely where it enters the eye. Optic neuropathy is a similar damage of the optic nerve due to a blockage of its blood supply, to nutritional deficiencies, or to toxins. Optic neuritis that may be caused by a viral infection refers to the inflammation of the optic nerve

Corneal Disorders
The cornea represents the domed covering in the front of the eye that protects the iris and lens and helps focus light on the retina. Among the chief corneal diseases, superficial punctate keratitis is one in which death of cells on the surface of the cornea occur. In this disorder, the eyes are generally painful, watery, sensitive to bright light, and vision could be slightly blurred. Corneal ulcers which are open sores on the cornea lead to complications like deep-seated infections, perforation of the cornea, displacement of the iris, and deconstruction of the eyes. Peripheral ulcerative keratitis is another inflammation and ulceration of the cornea that often occurs in people who have connective tissue diseases such as rheumatoid arthritis. Bullous keratopathy or swelling of the cornea is most common corneal disorder older people and can be treated by reducing the amount of fluid in the cornea.

Cataract and Glaucoma
Currently, the leading cause of preventable blindness worldwide can be attributed to cataracts which are clouding of the natural crystalline lens of the eyes. This clouding arises due to a number of factors like aging process, eye trauma, heredity, diabetes, and even some medications. Glaucoma is another sight-threatening optic nerve disease which is often related to elevated intraocular pressure. Damage to the eyes caused by infection, inflammation, tumor, surgery for cataracts, or other conditions keeps the fluid from draining freely and leads to increased eye pressure along with optic nerve damage, otherwise called as secondary glaucoma.

Disorders of the Conjunctiva and Sclera
The thin, transparent lining that covers the back of the eyelid and loops back to cover the sclera, till the edge of the cornea is named as the conjunctiva. This lining protects the eye by keeping small foreign objects and infection-causing microorganisms away and by contributing to the maintenance of the tear film. Conjunctivitis is the most common disorder of the conjunctiva which can be caused by viruses, bacteria, or fungi. Trachoma or granular conjunctivitis is believed to be the leading preventable cause of blindness in the world which results from chronic infections with certain non-sexually transmitted strains of Chlamydia trachomatis. Episcleritis or the inflammation of tissues lying between the sclera and the conjunctiva occurs in younger adults often. Scleritis is the most common corneal disorder among people in their 30s through 50s wherein a deep, extremely painful inflammation and purple discoloration of the sclera occurs that may severely damage vision.

Table of Contents

Executive Summary 3
Sectoral Analysis 8
Assessment of Investor Ecosystems 16
Analyst Insights and Recommendations 31
Patents 38
Key Contacts 42
Decision Support Database 45
About Frost & Sullivan 50

Read the full report:
Breakthroughs in Ophthalmic Devices and Drug Delivery Technologies (Technical Insights)

For more information:
Sarah Smith
Research Advisor at Reportbuyer.com
Email: [email protected]  
Tel: +44 208 816 85 48
Website: www.reportbuyer.com

SOURCE ReportBuyer

More Stories By PR Newswire

Copyright © 2007 PR Newswire. All rights reserved. Republication or redistribution of PRNewswire content is expressly prohibited without the prior written consent of PRNewswire. PRNewswire shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.

Latest Stories
@ThingsExpo has been named the Top 5 Most Influential M2M Brand by Onalytica in the ‘Machine to Machine: Top 100 Influencers and Brands.' Onalytica analyzed the online debate on M2M by looking at over 85,000 tweets to provide the most influential individuals and brands that drive the discussion. According to Onalytica the "analysis showed a very engaged community with a lot of interactive tweets. The M2M discussion seems to be more fragmented and driven by some of the major brands present in the...
In the 21st century, security on the Internet has become one of the most important issues. We hear more and more about cyber-attacks on the websites of large corporations, banks and even small businesses. When online we’re concerned not only for our own safety but also our privacy. We have to know that hackers usually start their preparation by investigating the private information of admins – the habits, interests, visited websites and so on. On the other hand, our own security is in danger bec...
Enterprises have been using both Big Data and virtualization for years. Until recently, however, most enterprises have not combined the two. Big Data's demands for higher levels of performance, the ability to control quality-of-service (QoS), and the ability to adhere to SLAs have kept it on bare metal, apart from the modern data center cloud. With recent technology innovations, we've seen the advantages of bare metal erode to such a degree that the enhanced flexibility and reduced costs that cl...
Fact: storage performance problems have only gotten more complicated, as applications not only have become largely virtualized, but also have moved to cloud-based infrastructures. Storage performance in virtualized environments isn’t just about IOPS anymore. Instead, you need to guarantee performance for individual VMs, helping applications maintain performance as the number of VMs continues to go up in real time. In his session at Cloud Expo, Dhiraj Sehgal, Product and Marketing at Tintri, wil...
As software becomes more and more complex, we, as software developers, have been splitting up our code into smaller and smaller components. This is also true for the environment in which we run our code: going from bare metal, to VMs to the modern-day Cloud Native world of containers, schedulers and microservices. While we have figured out how to run containerized applications in the cloud using schedulers, we've yet to come up with a good solution to bridge the gap between getting your conta...
19th Cloud Expo, taking place November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA, will feature technical sessions from a rock star conference faculty and the leading industry players in the world. Cloud computing is now being embraced by a majority of enterprises of all sizes. Yesterday's debate about public vs. private has transformed into the reality of hybrid cloud: a recent survey shows that 74% of enterprises have a hybrid cloud strategy. Meanwhile, 94% of enterpri...
Amazon has gradually rolled out parts of its IoT offerings, but these are just the tip of the iceberg. In addition to optimizing their backend AWS offerings, Amazon is laying the ground work to be a major force in IoT - especially in the connected home and office. In his session at @ThingsExpo, Chris Kocher, founder and managing director of Grey Heron, explained how Amazon is extending its reach to become a major force in IoT by building on its dominant cloud IoT platform, its Dash Button strat...
SYS-CON Events announced today that Streamlyzer will exhibit at the 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. Streamlyzer is a powerful analytics for video streaming service that enables video streaming providers to monitor and analyze QoE (Quality-of-Experience) from end-user devices in real time.
You have great SaaS business app ideas. You want to turn your idea quickly into a functional and engaging proof of concept. You need to be able to modify it to meet customers' needs, and you need to deliver a complete and secure SaaS application. How could you achieve all the above and yet avoid unforeseen IT requirements that add unnecessary cost and complexity? You also want your app to be responsive in any device at any time. In his session at 19th Cloud Expo, Mark Allen, General Manager of...
Without lifecycle traceability and visibility across the tool chain, stakeholders from Planning-to-Ops have limited insight and answers to who, what, when, why and how across the DevOps lifecycle. This impacts the ability to deliver high quality software at the needed velocity to drive positive business outcomes. In his general session at @DevOpsSummit at 19th Cloud Expo, Eric Robertson, General Manager at CollabNet, will discuss how customers are able to achieve a level of transparency that e...
Cloud based infrastructure deployment is becoming more and more appealing to customers, from Fortune 500 companies to SMEs due to its pay-as-you-go model. Enterprise storage vendors are able to reach out to these customers by integrating in cloud based deployments; this needs adaptability and interoperability of the products confirming to cloud standards such as OpenStack, CloudStack, or Azure. As compared to off the shelf commodity storage, enterprise storages by its reliability, high-availabil...
The IoT industry is now at a crossroads, between the fast-paced innovation of technologies and the pending mass adoption by global enterprises. The complexity of combining rapidly evolving technologies and the need to establish practices for market acceleration pose a strong challenge to global enterprises as well as IoT vendors. In his session at @ThingsExpo, Clark Smith, senior product manager for Numerex, will discuss how Numerex, as an experienced, established IoT provider, has embraced a ...
DevOps theory promotes a culture of continuous improvement built on collaboration, empowerment, systems thinking, and feedback loops. But how do you collaborate effectively across the traditional silos? How can you make decisions without system-wide visibility? How can you see the whole system when it is spread across teams and locations? How do you close feedback loops across teams and activities delivering complex multi-tier, cloud, container, serverless, and/or API-based services?
Today every business relies on software to drive the innovation necessary for a competitive edge in the Application Economy. This is why collaboration between development and operations, or DevOps, has become IT’s number one priority. Whether you are in Dev or Ops, understanding how to implement a DevOps strategy can deliver faster development cycles, improved software quality, reduced deployment times and overall better experiences for your customers.
The Internet of Things (IoT), in all its myriad manifestations, has great potential. Much of that potential comes from the evolving data management and analytic (DMA) technologies and processes that allow us to gain insight from all of the IoT data that can be generated and gathered. This potential may never be met as those data sets are tied to specific industry verticals and single markets, with no clear way to use IoT data and sensor analytics to fulfill the hype being given the IoT today.