|By PR Newswire||
|March 21, 2014 03:12 PM EDT||
LONDON, March 21, 2014 /PRNewswire/ -- Bee Colony Collapse Disorder (CCD) is increasing with unknown cause(s). There is no effective treatment or prevention of CCD. Increasing loss of bee colonies since 2005 is resulting in the loss of bee pollination which poses a threat to food production worldwide.
Bioradar UK Ltd. announced today that the principal organisms associated to date with Colony Collapse Disorder (CCD) in bees, all have increased concentrations of a structure in their genes, which the Replikins scientists have named Beetoxingene™. These CCD genes are related to the specific Replikin gene sequence structures previously described in which relate to infectivity and lethality (1-8).
In the present study, Bioradar software was used to analyze annually all the gene sequence data available on PubMed data bases, independently for Replikins in each organism for which there is evidence of involvement in CCD in all pre-outbreak years available and in the years of the current CCD outbreaks 2005-2013. The genes of organisms such as Varroa Destructor mite, Nosema Cerenae fungus, and bee viruses including Sackbrood, Israeli, and Kashmir strains, were each independently found to have increased Replikin Counts, Beetoxingene Counts, at p<0.001 at the same times as the lethal CCD pandemic was occuring. The highest Counts, up to over 10, were found in the genes of the bees themselves.
Most important, the increases in the bees and in each of the associated organisms was found to occur at the same times. Annual mean Beetoxingene Counts (number per 100 amino acids) pre-outbreak, before CCD, in each of the organisms and in the bees were usually approximately 2. Increases and peaks of Counts were observed during the CCD pandemic years both preceding and at the height of CCD attacks (see Figure). The results in the Figure also show a correlation in time between two cycles of independent peak Counts in the two organisms, Varroa Destructor and Sackbrood virus as well as in the bee gene.
The Beetoxingenes may increase independently in each organism and in the bees, and the associated organisms of the CCD simply may be multiple independent hosts and carriers of lethal Beetoxingenes. Alternately, the Beetoxingenes may be transferred from the individual organisms to the genes of the bee. The Beetoxingene Counts in individual organisms may not be sufficient to kill the individual organism, permitting each to function as a carrier to the ultimate host, the bee, where the cumulative Counts reach double or triple that of each individual organism (see Figure), and where the cumulative doses kill the bee.
Increase in Replikin and Beetoxingene Counts has been found to be related to lethality, and Replikins blockers and vaccines have been shown to act effectively against Replikins disorders. However, all of Koch's Postulates for causality have not yet been fulfilled, and increased Beetoxingene Counts do not alone exclude other as yet unidentified CCD pathogens which carry Replikins in their genes.
These findings are the basis of specific solid phase synthetic Anti-Beetoxingene Blockers™ and Vaccines against CCD in bees like those found effective against H5N1 influenza virus in chickens and against Taura Syndrome Virus in shrimp.
The findings will be presented at the World Vaccine Congress at the Marriot Wardman Park Hotel Washington D.C. March 24th to 26th 2014.
Contact: Anne Borsanyi
1. Bogoch S and Bogoch ES.Genome Replikin Count Predicts Increased Infectivity/Lethality of Viruses doi:10.1038/npre.2012.7144.1
2. Bogoch S and Bogoch ES. Genome Replikin Count Predicts Increased Lethality of Cancer. doi:10.1038/npre.2012.7143.1
3. Bogoch S and Bogoch ES. Genomic Replikin Count Predicts Increased Lethality of Malaria doi:10.1038/npre.2012.7142.1
4. Bogoch S and Bogoch ES Genome Replikin Count Predicts Increased Lethality of Resistant Tuberculosis doi:10.1038/npre.2012.7141.1
5. Bogoch S and Bogoch ES Genomic Replikin Counts of Infectious Salmon Anemia Virus (ISAV) in Canada Exceed the Counts in Lethal Outbreaks in Norway, Chile, and Scotland. Real-Time Tracking of the Evolution of the ISAV Genome and the Resultant Replikins Solid Phase ISAV Vaccine Make ISAV Pandemic Prevention Possible. doi:10.1038/npre.2012.6991.1 6. Bogoch S and Bogoch ES Bogoch Replikins Pandemic Prevention: Increase of Strain-Specific Influenza Genomic Replikin Counts, Having Predicted Outbreaks and their Location Seven Times Consecutively, Up to Two Years in Advance, Provides Time for Prevention of Pandemics doi:10.1038/npre.2012.6952.1
7. Bogoch S and Bogoch ES Marked Rise in Replikin Counts in H5N1 Influenza Virus Localized to Lethality Gene p B1. doi:10.1038/npre.2011.6420.1
8. Bogoch S and Bogoch ES Prediction of specific virus outbreaks made from the increased concentration of a new class of virus genomic peptides, replikins. doi:10.1038/npre.2011.6279.1
Read more news from Bioradar UK Ltd.
SOURCE Bioradar UK, Ltd.
The essence of cloud computing is that all consumable IT resources are delivered as services. In his session at 15th Cloud Expo, Yung Chou, Technology Evangelist at Microsoft, demonstrated the concepts and implementations of two important cloud computing deliveries: Infrastructure as a Service (IaaS) and Platform as a Service (PaaS). He discussed from business and technical viewpoints what exactly they are, why we care, how they are different and in what ways, and the strategies for IT to transi...
Mar. 29, 2017 05:00 AM EDT Reads: 6,392
All organizations that did not originate this moment have a pre-existing culture as well as legacy technology and processes that can be more or less amenable to DevOps implementation. That organizational culture is influenced by the personalities and management styles of Executive Management, the wider culture in which the organization is situated, and the personalities of key team members at all levels of the organization. This culture and entrenched interests usually throw a wrench in the work...
Mar. 29, 2017 04:00 AM EDT Reads: 3,166
The Internet of Things is clearly many things: data collection and analytics, wearables, Smart Grids and Smart Cities, the Industrial Internet, and more. Cool platforms like Arduino, Raspberry Pi, Intel's Galileo and Edison, and a diverse world of sensors are making the IoT a great toy box for developers in all these areas. In this Power Panel at @ThingsExpo, moderated by Conference Chair Roger Strukhoff, panelists discussed what things are the most important, which will have the most profound e...
Mar. 29, 2017 04:00 AM EDT Reads: 15,068
Keeping pace with advancements in software delivery processes and tooling is taxing even for the most proficient organizations. Point tools, platforms, open source and the increasing adoption of private and public cloud services requires strong engineering rigor - all in the face of developer demands to use the tools of choice. As Agile has settled in as a mainstream practice, now DevOps has emerged as the next wave to improve software delivery speed and output. To make DevOps work, organization...
Mar. 29, 2017 03:45 AM EDT Reads: 2,120
Niagara Networks exhibited at the 19th International Cloud Expo, which took place at the Santa Clara Convention Center in Santa Clara, CA, in November 2016. Niagara Networks offers the highest port-density systems, and the most complete Next-Generation Network Visibility systems including Network Packet Brokers, Bypass Switches, and Network TAPs.
Mar. 29, 2017 03:30 AM EDT Reads: 3,335
Virtualization over the past years has become a key strategy for IT to acquire multi-tenancy, increase utilization, develop elasticity and improve security. And virtual machines (VMs) are quickly becoming a main vehicle for developing and deploying applications. The introduction of containers seems to be bringing another and perhaps overlapped solution for achieving the same above-mentioned benefits. Are a container and a virtual machine fundamentally the same or different? And how? Is one techn...
Mar. 29, 2017 03:30 AM EDT Reads: 3,197
Extreme Computing is the ability to leverage highly performant infrastructure and software to accelerate Big Data, machine learning, HPC, and Enterprise applications. High IOPS Storage, low-latency networks, in-memory databases, GPUs and other parallel accelerators are being used to achieve faster results and help businesses make better decisions. In his session at 18th Cloud Expo, Michael O'Neill, Strategic Business Development at NVIDIA, focused on some of the unique ways extreme computing is...
Mar. 29, 2017 03:30 AM EDT Reads: 11,720
My team embarked on building a data lake for our sales and marketing data to better understand customer journeys. This required building a hybrid data pipeline to connect our cloud CRM with the new Hadoop Data Lake. One challenge is that IT was not in a position to provide support until we proved value and marketing did not have the experience, so we embarked on the journey ourselves within the product marketing team for our line of business within Progress. In his session at @BigDataExpo, Sum...
Mar. 29, 2017 03:30 AM EDT Reads: 3,201
Web Real-Time Communication APIs have quickly revolutionized what browsers are capable of. In addition to video and audio streams, we can now bi-directionally send arbitrary data over WebRTC's PeerConnection Data Channels. With the advent of Progressive Web Apps and new hardware APIs such as WebBluetooh and WebUSB, we can finally enable users to stitch together the Internet of Things directly from their browsers while communicating privately and securely in a decentralized way.
Mar. 29, 2017 03:00 AM EDT Reads: 6,059
Information technology (IT) advances are transforming the way we innovate in business, thereby disrupting the old guard and their predictable status-quo. It’s creating global market turbulence. Industries are converging, and new opportunities and threats are emerging, like never before. So, how are savvy chief information officers (CIOs) leading this transition? Back in 2015, the IBM Institute for Business Value conducted a market study that included the findings from over 1,800 CIO interviews ...
Mar. 29, 2017 01:45 AM EDT Reads: 5,419
DevOps is often described as a combination of technology and culture. Without both, DevOps isn't complete. However, applying the culture to outdated technology is a recipe for disaster; as response times grow and connections between teams are delayed by technology, the culture will die. A Nutanix Enterprise Cloud has many benefits that provide the needed base for a true DevOps paradigm.
Mar. 29, 2017 01:15 AM EDT Reads: 2,476
"We host and fully manage cloud data services, whether we store, the data, move the data, or run analytics on the data," stated Kamal Shannak, Senior Development Manager, Cloud Data Services, IBM, in this SYS-CON.tv interview at 18th Cloud Expo, held June 7-9, 2016, at the Javits Center in New York City, NY.
Mar. 29, 2017 01:15 AM EDT Reads: 9,191
What sort of WebRTC based applications can we expect to see over the next year and beyond? One way to predict development trends is to see what sorts of applications startups are building. In his session at @ThingsExpo, Arin Sime, founder of WebRTC.ventures, will discuss the current and likely future trends in WebRTC application development based on real requests for custom applications from real customers, as well as other public sources of information,
Mar. 29, 2017 01:00 AM EDT Reads: 1,094
Whether you like it or not, DevOps is on track for a remarkable alliance with security. The SEC didn’t approve the merger. And your boss hasn’t heard anything about it. Yet, this unruly triumvirate will soon dominate and deliver DevSecOps faster, cheaper, better, and on an unprecedented scale. In his session at DevOps Summit, Frank Bunger, VP of Customer Success at ScriptRock, discussed how this cathartic moment will propel the DevOps movement from such stuff as dreams are made on to a practic...
Mar. 29, 2017 12:15 AM EDT Reads: 8,473
Interoute has announced the integration of its Global Cloud Infrastructure platform with Rancher Labs’ container management platform, Rancher. This approach enables enterprises to accelerate their digital transformation and infrastructure investments. Matthew Finnie, Interoute CTO commented “Enterprises developing and building apps in the cloud and those on a path to Digital Transformation need Digital ICT Infrastructure that allows them to build, test and deploy faster than ever before. The int...
Mar. 29, 2017 12:15 AM EDT Reads: 1,399