|By PR Newswire||
|March 21, 2014 03:12 PM EDT||
LONDON, March 21, 2014 /PRNewswire/ -- Bee Colony Collapse Disorder (CCD) is increasing with unknown cause(s). There is no effective treatment or prevention of CCD. Increasing loss of bee colonies since 2005 is resulting in the loss of bee pollination which poses a threat to food production worldwide.
Bioradar UK Ltd. announced today that the principal organisms associated to date with Colony Collapse Disorder (CCD) in bees, all have increased concentrations of a structure in their genes, which the Replikins scientists have named Beetoxingene™. These CCD genes are related to the specific Replikin gene sequence structures previously described in which relate to infectivity and lethality (1-8).
In the present study, Bioradar software was used to analyze annually all the gene sequence data available on PubMed data bases, independently for Replikins in each organism for which there is evidence of involvement in CCD in all pre-outbreak years available and in the years of the current CCD outbreaks 2005-2013. The genes of organisms such as Varroa Destructor mite, Nosema Cerenae fungus, and bee viruses including Sackbrood, Israeli, and Kashmir strains, were each independently found to have increased Replikin Counts, Beetoxingene Counts, at p<0.001 at the same times as the lethal CCD pandemic was occuring. The highest Counts, up to over 10, were found in the genes of the bees themselves.
Most important, the increases in the bees and in each of the associated organisms was found to occur at the same times. Annual mean Beetoxingene Counts (number per 100 amino acids) pre-outbreak, before CCD, in each of the organisms and in the bees were usually approximately 2. Increases and peaks of Counts were observed during the CCD pandemic years both preceding and at the height of CCD attacks (see Figure). The results in the Figure also show a correlation in time between two cycles of independent peak Counts in the two organisms, Varroa Destructor and Sackbrood virus as well as in the bee gene.
The Beetoxingenes may increase independently in each organism and in the bees, and the associated organisms of the CCD simply may be multiple independent hosts and carriers of lethal Beetoxingenes. Alternately, the Beetoxingenes may be transferred from the individual organisms to the genes of the bee. The Beetoxingene Counts in individual organisms may not be sufficient to kill the individual organism, permitting each to function as a carrier to the ultimate host, the bee, where the cumulative Counts reach double or triple that of each individual organism (see Figure), and where the cumulative doses kill the bee.
Increase in Replikin and Beetoxingene Counts has been found to be related to lethality, and Replikins blockers and vaccines have been shown to act effectively against Replikins disorders. However, all of Koch's Postulates for causality have not yet been fulfilled, and increased Beetoxingene Counts do not alone exclude other as yet unidentified CCD pathogens which carry Replikins in their genes.
These findings are the basis of specific solid phase synthetic Anti-Beetoxingene Blockers™ and Vaccines against CCD in bees like those found effective against H5N1 influenza virus in chickens and against Taura Syndrome Virus in shrimp.
The findings will be presented at the World Vaccine Congress at the Marriot Wardman Park Hotel Washington D.C. March 24th to 26th 2014.
Contact: Anne Borsanyi
1. Bogoch S and Bogoch ES.Genome Replikin Count Predicts Increased Infectivity/Lethality of Viruses doi:10.1038/npre.2012.7144.1
2. Bogoch S and Bogoch ES. Genome Replikin Count Predicts Increased Lethality of Cancer. doi:10.1038/npre.2012.7143.1
3. Bogoch S and Bogoch ES. Genomic Replikin Count Predicts Increased Lethality of Malaria doi:10.1038/npre.2012.7142.1
4. Bogoch S and Bogoch ES Genome Replikin Count Predicts Increased Lethality of Resistant Tuberculosis doi:10.1038/npre.2012.7141.1
5. Bogoch S and Bogoch ES Genomic Replikin Counts of Infectious Salmon Anemia Virus (ISAV) in Canada Exceed the Counts in Lethal Outbreaks in Norway, Chile, and Scotland. Real-Time Tracking of the Evolution of the ISAV Genome and the Resultant Replikins Solid Phase ISAV Vaccine Make ISAV Pandemic Prevention Possible. doi:10.1038/npre.2012.6991.1 6. Bogoch S and Bogoch ES Bogoch Replikins Pandemic Prevention: Increase of Strain-Specific Influenza Genomic Replikin Counts, Having Predicted Outbreaks and their Location Seven Times Consecutively, Up to Two Years in Advance, Provides Time for Prevention of Pandemics doi:10.1038/npre.2012.6952.1
7. Bogoch S and Bogoch ES Marked Rise in Replikin Counts in H5N1 Influenza Virus Localized to Lethality Gene p B1. doi:10.1038/npre.2011.6420.1
8. Bogoch S and Bogoch ES Prediction of specific virus outbreaks made from the increased concentration of a new class of virus genomic peptides, replikins. doi:10.1038/npre.2011.6279.1
Read more news from Bioradar UK Ltd.
SOURCE Bioradar UK, Ltd.
The explosion of new web/cloud/IoT-based applications and the data they generate are transforming our world right before our eyes. In this rush to adopt these new technologies, organizations are often ignoring fundamental questions concerning who owns the data and failing to ask for permission to conduct invasive surveillance of their customers. Organizations that are not transparent about how their systems gather data telemetry without offering shared data ownership risk product rejection, regu...
Feb. 20, 2017 08:45 AM EST
Information technology (IT) advances are transforming the way we innovate in business, thereby disrupting the old guard and their predictable status-quo. It’s creating global market turbulence. Industries are converging, and new opportunities and threats are emerging, like never before. So, how are savvy chief information officers (CIOs) leading this transition? Back in 2015, the IBM Institute for Business Value conducted a market study that included the findings from over 1,800 CIO interviews ...
Feb. 20, 2017 08:45 AM EST Reads: 1,387
SYS-CON Events announced today that Enzu will exhibit at SYS-CON's 20th International Cloud Expo®, which will take place on June 6-8, 2017, at the Javits Center in New York City, NY, and the 21st International Cloud Expo®, which will take place October 31-November 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA. Enzu’s mission is to be the leading provider of enterprise cloud solutions worldwide. Enzu enables online businesses to use its IT infrastructure to their competitive ad...
Feb. 20, 2017 08:30 AM EST Reads: 2,191
Who are you? How do you introduce yourself? Do you use a name, or do you greet a friend by the last four digits of his social security number? Assuming you don’t, why are we content to associate our identity with 10 random digits assigned by our phone company? Identity is an issue that affects everyone, but as individuals we don’t spend a lot of time thinking about it. In his session at @ThingsExpo, Ben Klang, Founder & President of Mojo Lingo, discussed the impact of technology on identity. Sho...
Feb. 20, 2017 08:30 AM EST Reads: 5,104
@DevOpsSummit has been named the ‘Top DevOps Influencer' by iTrend. iTrend processes millions of conversations, tweets, interactions, news articles, press releases, blog posts - and extract meaning form them and analyzes mobile and desktop software platforms used to communicate, various metadata (such as geo location), and automation tools. In overall placement, @DevOpsSummit ranked as the number one ‘DevOps Influencer' followed by @CloudExpo at third, and @MicroservicesE at 24th.
Feb. 20, 2017 08:30 AM EST Reads: 940
There are 66 million network cameras capturing terabytes of data. How did factories in Japan improve physical security at the facilities and improve employee productivity? Edge Computing reduces possible kilobytes of data collected per second to only a few kilobytes of data transmitted to the public cloud every day. Data is aggregated and analyzed close to sensors so only intelligent results need to be transmitted to the cloud. Non-essential data is recycled to optimize storage.
Feb. 20, 2017 08:15 AM EST Reads: 1,135
In his keynote at @ThingsExpo, Chris Matthieu, Director of IoT Engineering at Citrix and co-founder and CTO of Octoblu, focused on building an IoT platform and company. He provided a behind-the-scenes look at Octoblu’s platform, business, and pivots along the way (including the Citrix acquisition of Octoblu).
Feb. 20, 2017 07:45 AM EST Reads: 105
WebRTC is the future of browser-to-browser communications, and continues to make inroads into the traditional, difficult, plug-in web communications world. The 6th WebRTC Summit continues our tradition of delivering the latest and greatest presentations within the world of WebRTC. Topics include voice calling, video chat, P2P file sharing, and use cases that have already leveraged the power and convenience of WebRTC.
Feb. 20, 2017 07:30 AM EST Reads: 143
In his keynote at 18th Cloud Expo, Andrew Keys, Co-Founder of ConsenSys Enterprise, provided an overview of the evolution of the Internet and the Database and the future of their combination – the Blockchain. Andrew Keys is Co-Founder of ConsenSys Enterprise. He comes to ConsenSys Enterprise with capital markets, technology and entrepreneurial experience. Previously, he worked for UBS investment bank in equities analysis. Later, he was responsible for the creation and distribution of life settle...
Feb. 20, 2017 07:15 AM EST Reads: 113
Stratoscale, the software company developing the next generation data center operating system, exhibited at SYS-CON's 18th International Cloud Expo®, which took place at the Javits Center in New York City, NY, in June 2016.Stratoscale is revolutionizing the data center with a zero-to-cloud-in-minutes solution. With Stratoscale’s hardware-agnostic, Software Defined Data Center (SDDC) solution to store everything, run anything and scale everywhere, IT is empowered to take control of their data ce...
Feb. 20, 2017 07:15 AM EST Reads: 666
In his session at @DevOpsSummit at 19th Cloud Expo, Robert Doyle, lead architect at eCube Systems, will examine the issues and need for an agile infrastructure and show the advantages of capturing developer knowledge in an exportable file for migration into production. He will introduce the use of NXTmonitor, a next-generation DevOps tool that captures application environments, dependencies and start/stop procedures in a portable configuration file with an easy-to-use GUI. In addition to captur...
Feb. 20, 2017 07:15 AM EST Reads: 3,376
SYS-CON Events announced today that SD Times | BZ Media has been named “Media Sponsor” of SYS-CON's 20th International Cloud Expo, which will take place on June 6–8, 2017, at the Javits Center in New York City, NY. BZ Media LLC is a high-tech media company that produces technical conferences and expositions, and publishes a magazine, newsletters and websites in the software development, SharePoint, mobile development and commercial UAV markets.
Feb. 20, 2017 07:00 AM EST Reads: 1,448
DevOps is being widely accepted (if not fully adopted) as essential in enterprise IT. But as Enterprise DevOps gains maturity, expands scope, and increases velocity, the need for data-driven decisions across teams becomes more acute. DevOps teams in any modern business must wrangle the ‘digital exhaust’ from the delivery toolchain, "pervasive" and "cognitive" computing, APIs and services, mobile devices and applications, the Internet of Things, and now even blockchain.
Feb. 20, 2017 06:45 AM EST Reads: 276
In the first article of this three-part series on hybrid cloud security, we discussed the Shared Responsibility Model and examined how the most common attack strategies persist, are amplified, or are mitigated as assets move from data centers to the cloud. Today, we’ll look at some of the unique security challenges that are introduced by public cloud environments. While cloud computing delivers many operational, cost-saving and security benefits, it takes place in a public, shared and on-demand ...
Feb. 20, 2017 06:30 AM EST Reads: 1,087
Both SaaS vendors and SaaS buyers are going “all-in” to hyperscale IaaS platforms such as AWS, which is disrupting the SaaS value proposition. Why should the enterprise SaaS consumer pay for the SaaS service if their data is resident in adjacent AWS S3 buckets? If both SaaS sellers and buyers are using the same cloud tools, automation and pay-per-transaction model offered by IaaS platforms, then why not host the “shrink-wrapped” software in the customers’ cloud? Further, serverless computing, cl...
Feb. 20, 2017 06:00 AM EST Reads: 1,611