|By PR Newswire||
|March 25, 2014 03:00 AM EDT||
-- Asymptote's liquid nitrogen-free cryogenic solutions are aligned with most of the cutting-edge technologies in the fields of regenerative medicine, stem cells, tissue transplantation and biobanking
LONDON, March 25, 2014 /PRNewswire/ -- Based on its recent analysis of the cryopreservation industry, Frost & Sullivan recognizes Asymptote Limited (Asymptote) with the 2014 European Frost & Sullivan Award for Technology Innovation Leadership. Asymptote's commitment to providing novel, effective and environmental-friendly cryopreservation solutions is evident from its efforts to produce a liquid nitrogen-free, good manufacturing practices (cGMP)-compliant cold chain comprising end-to-end cryopreservation, shipping, and thawing of materials.
"Asymptote's portable, self-charging, cryogenic solutions aim to improve the storage of live vaccines in developing nations. It has excelled in developing ultra-low-temperature storage equipment that helps to prevent the discarding of vaccines due to thermal stabilisation problems," said Frost & Sullivan Senior Research Analyst Cecilia Van Cauwenberghe. "The company, which is innovatively using electrically powered Stirling cryocoolers in cryopreservation equipment, expects to significantly improve the distribution of live vaccines in territories where liquid nitrogen is not readily available and the supply of electricity is unreliable."
Asymptote's current low-volume liquid nitrogen-free cryocooler, the EF600-controlled rate freezer, consists of a low-cost, ultra-portable cryocooler, specifically designed for the cryopreservation of stem cells, embryos, and spermatozoa. It demonstrates a high level of cooling rate control accuracy, while simultaneously being simple and easy to handle. It supports numerous sample formats and enables the lab technician to work with linear as well as non-linear cooling profiles.
As EF600s do not require liquid nitrogen, the running costs are estimated to be one per cent of that of liquid nitrogen-controlled rate freezing. By not using liquid nitrogen and its detrimental effects on sterility, particulate generation, and oxygen depletion, the solution is ideal for use in Grade B clean rooms and can be adapted for use in operating rooms for the optimised cryopreservation of source material for autologous treatments.
The new VIA Freeze™ range of controlled rate freezers are designed to be very easy to use with a touch screen interface and remote access (with 21 CRF 11 compliance) can be used with the SBS plate standards from 1-4 plates. This allows users to easily program and upload cooling profiles for further validation and report generation. Furthermore designed to minimise temperature gradients, the VIA Freeze™ achieves precision control of the cooling rate and the temperature. The systems can also be adapted to be used with bespoke systems and automation if required. Since Asymptote's cryogenic solutions (controlled rate freezers and long term storage solutions) do not use liquid nitrogen they do not require the liquid nitrogen infrastructure and the associated health and safety systems required by other systems or the ongoing liquid nitrogen running costs and possibilities of contamination from liquid nitrogen.
The VIA Freeze™ enables the cryopreservation of cells in different formats such as cryovials, cryobags and cassettes. With a capacity of 250 cryovials, the VIA Freeze™ represents the best option for the creation of seed cell banks (SCBs) and master cell banks (MCBs), which require validated, reproducible, and safe methods of freezing cells during their creation.
Asymptote has also developed a novel active nucleation biocompatible material named 'IceStart™' that helps to reduce the damage caused by supercooling during the cryopreservation process. Compared to other products in the market, IceStart™ induces ice nucleation closer to the freezing point of the solution. This results in an important reduction in the number of samples that are subjected to extreme undercooling. Consequently the viability of the cells is substantially increased.
Asymptote's research in cryopreservation is based on five principal projects - the development of a GMP cryogenic cold chain for the clinical delivery of regenerative medicine therapeutics; the development of coatings that induce ice nucleation; an improved method of freeze drying; the development of a portable, self-charging cryogenic vessel for the shipment and short-term storage of cryopreserved material; and the development and testing of technology for the cryopreservation of hepatocytes in microtiter plates for subsequent screening applications. These projects are carried out in collaboration with its customers, in order to continuously improve their results and ensure that their needs are met.
"The company is currently proposing the development of the first GMP-compliant cryogenic cold chain for the clinical delivery of regenerative medicine therapeutics. Asymptote is also developing an ice-nucleating coating for the inside of vessels that are used for cryopreservation, which will overcome the problems caused by random ice nucleation and improve cell recovery upon thawing," noted Van Cauwenberghe. "The company expects to determine the real impact of these new developments in the market, as well as their disruptive influence on an existing solution or the creation of new products."
Each year, Frost & Sullivan presents this award to the company that has demonstrated uniqueness in developing and leveraging new technologies, which significantly impacts both the functionality and the customer value of the new products and applications. The award lauds the high R&D spend towards innovation, its relevance to the industry and the positive impact on brand perception.
Frost & Sullivan Best Practices awards recognize companies in a variety of regional and global markets for demonstrating outstanding achievement and superior performance in areas such as leadership, technological innovation, customer service and strategic product development. Industry analysts compare market participants and measure performance through in-depth interviews, analysis and extensive secondary research to identify best practices in the industry.
About Asymptote Limited
Based in Cambridge, UK, Asymptote Limited is excelling in the development of products and process technologies that are adapted to its customers' requirements. Having on board laureate cryopreservation specialists, Asymptote is innovating the cryopreservation market by providing novel, effective, and environment friendly solutions.
About Frost & Sullivan
Frost & Sullivan, the Growth Partnership Company, works in collaboration with clients to leverage visionary innovation that addresses the global challenges and related growth opportunities that will make or break today's market participants.
Our "Growth Partnership" supports clients by addressing these opportunities and incorporating two key elements driving visionary innovation: The Integrated Value Proposition and The Partnership Infrastructure.
- The Integrated Value Proposition provides support to our clients throughout all phases of their journey to visionary innovation including: research, analysis, strategy, vision, innovation and implementation.
- The Partnership Infrastructure is entirely unique as it constructs the foundation upon which visionary innovation becomes possible. This includes our 360 degree research, comprehensive industry coverage, career best practices as well as our global footprint of more than 40 offices.
For more than 50 years, we have been developing growth strategies for the global 1000, emerging businesses, the public sector and the investment community. Is your organization prepared for the next profound wave of industry convergence, disruptive technologies, increasing competitive intensity, Mega Trends, breakthrough best practices, changing customer dynamics and emerging economies?
Best Practices, Frost & Sullivan
E: [email protected]
P: +44 (0) 207 915 7867
One of the hottest areas in cloud right now is DRaaS and related offerings. In his session at 16th Cloud Expo, Dale Levesque, Disaster Recovery Product Manager with Windstream's Cloud and Data Center Marketing team, will discuss the benefits of the cloud model, which far outweigh the traditional approach, and how enterprises need to ensure that their needs are properly being met.
Jul. 30, 2015 07:00 AM EDT Reads: 1,671
The speed of software changes in growing and large scale rapid-paced DevOps environments presents a challenge for continuous testing. Many organizations struggle to get this right. Practices that work for small scale continuous testing may not be sufficient as the requirements grow. In his session at DevOps Summit, Marc Hornbeek, Sr. Solutions Architect of DevOps continuous test solutions at Spirent Communications, explained the best practices of continuous testing at high scale, which is rele...
Jul. 29, 2015 11:45 PM EDT Reads: 1,367
"We got started as search consultants. On the services side of the business we have help organizations save time and save money when they hit issues that everyone more or less hits when their data grows," noted Otis Gospodnetić, Founder of Sematext, in this SYS-CON.tv interview at @DevOpsSummit, held June 9-11, 2015, at the Javits Center in New York City.
Jul. 29, 2015 11:45 PM EDT Reads: 1,022
"We have been in business for 21 years and have been building many enterprise solutions, all IT plumbing - server, storage, interconnects," stated Alex Gorbachev, President of Intelligent Systems Services, in this SYS-CON.tv interview at 16th Cloud Expo, held June 9-11, 2015, at the Javits Center in New York City.
Jul. 29, 2015 10:45 PM EDT Reads: 1,027
In a recent research, analyst firm IDC found that the average cost of a critical application failure is $500,000 to $1 million per hour and the average total cost of unplanned application downtime is $1.25 billion to $2.5 billion per year for Fortune 1000 companies. In addition to the findings on the cost of the downtime, the research also highlighted best practices for development, testing, application support, infrastructure, and operations teams.
Jul. 29, 2015 05:30 PM EDT
"We specialize in testing. DevOps is all about continuous delivery and accelerating the delivery pipeline and there is no continuous delivery without testing," noted Marc Hornbeek, Sr. Solutions Architect at Spirent Communications, in this SYS-CON.tv interview at @DevOpsSummit, held June 9-11, 2015, at the Javits Center in New York City.
Jul. 29, 2015 05:15 PM EDT Reads: 363
How do you securely enable access to your applications in AWS without exposing any attack surfaces? The answer is usually very complicated because application environments morph over time in response to growing requirements from your employee base, your partners and your customers. In his session at @DevOpsSummit, Haseeb Budhani, CEO and Co-founder of Soha, shared five common approaches that DevOps teams follow to secure access to applications deployed in AWS, Azure, etc., and the friction an...
Jul. 29, 2015 04:30 PM EDT Reads: 501
"Alert Logic is a managed security service provider that basically deploys technologies, but we support those technologies with the people and process behind it," stated Stephen Coty, Chief Security Evangelist at Alert Logic, in this SYS-CON.tv interview at 16th Cloud Expo, held June 9-11, 2015, at the Javits Center in New York City.
Jul. 29, 2015 04:15 PM EDT Reads: 328
Digital Transformation is the ultimate goal of cloud computing and related initiatives. The phrase is certainly not a precise one, and as subject to hand-waving and distortion as any high-falutin' terminology in the world of information technology. Yet it is an excellent choice of words to describe what enterprise IT—and by extension, organizations in general—should be working to achieve. Digital Transformation means: handling all the data types being found and created in the organizat...
Jul. 29, 2015 04:00 PM EDT Reads: 1,070
The Internet of Everything (IoE) brings together people, process, data and things to make networked connections more relevant and valuable than ever before – transforming information into knowledge and knowledge into wisdom. IoE creates new capabilities, richer experiences, and unprecedented opportunities to improve business and government operations, decision making and mission support capabilities.
Jul. 29, 2015 03:15 PM EDT Reads: 242
The essence of cloud computing is that all consumable IT resources are delivered as services. In his session at 15th Cloud Expo, Yung Chou, Technology Evangelist at Microsoft, demonstrated the concepts and implementations of two important cloud computing deliveries: Infrastructure as a Service (IaaS) and Platform as a Service (PaaS). He discussed from business and technical viewpoints what exactly they are, why we care, how they are different and in what ways, and the strategies for IT to tran...
Jul. 29, 2015 03:15 PM EDT Reads: 396
The Software Defined Data Center (SDDC), which enables organizations to seamlessly run in a hybrid cloud model (public + private cloud), is here to stay. IDC estimates that the software-defined networking market will be valued at $3.7 billion by 2016. Security is a key component and benefit of the SDDC, and offers an opportunity to build security 'from the ground up' and weave it into the environment from day one. In his session at 16th Cloud Expo, Reuven Harrison, CTO and Co-Founder of Tufin,...
Jul. 29, 2015 03:00 PM EDT Reads: 468
The Internet of Things is not only adding billions of sensors and billions of terabytes to the Internet. It is also forcing a fundamental change in the way we envision Information Technology. For the first time, more data is being created by devices at the edge of the Internet rather than from centralized systems. What does this mean for today's IT professional? In this Power Panel at @ThingsExpo, moderated by Conference Chair Roger Strukhoff, panelists addressed this very serious issue of pro...
Jul. 29, 2015 03:00 PM EDT Reads: 1,258
With SaaS use rampant across organizations, how can IT departments track company data and maintain security? More and more departments are commissioning their own solutions and bypassing IT. A cloud environment is amorphous and powerful, allowing you to set up solutions for all of your user needs: document sharing and collaboration, mobile access, e-mail, even industry-specific applications. In his session at 16th Cloud Expo, Shawn Mills, President and a founder of Green House Data, discussed h...
Jul. 29, 2015 02:30 PM EDT Reads: 326
Container technology is sending shock waves through the world of cloud computing. Heralded as the 'next big thing,' containers provide software owners a consistent way to package their software and dependencies while infrastructure operators benefit from a standard way to deploy and run them. Containers present new challenges for tracking usage due to their dynamic nature. They can also be deployed to bare metal, virtual machines and various cloud platforms. How do software owners track the usag...
Jul. 29, 2015 02:30 PM EDT Reads: 111