|By PR Newswire||
|March 25, 2014 03:00 AM EDT||
-- Asymptote's liquid nitrogen-free cryogenic solutions are aligned with most of the cutting-edge technologies in the fields of regenerative medicine, stem cells, tissue transplantation and biobanking
LONDON, March 25, 2014 /PRNewswire/ -- Based on its recent analysis of the cryopreservation industry, Frost & Sullivan recognizes Asymptote Limited (Asymptote) with the 2014 European Frost & Sullivan Award for Technology Innovation Leadership. Asymptote's commitment to providing novel, effective and environmental-friendly cryopreservation solutions is evident from its efforts to produce a liquid nitrogen-free, good manufacturing practices (cGMP)-compliant cold chain comprising end-to-end cryopreservation, shipping, and thawing of materials.
"Asymptote's portable, self-charging, cryogenic solutions aim to improve the storage of live vaccines in developing nations. It has excelled in developing ultra-low-temperature storage equipment that helps to prevent the discarding of vaccines due to thermal stabilisation problems," said Frost & Sullivan Senior Research Analyst Cecilia Van Cauwenberghe. "The company, which is innovatively using electrically powered Stirling cryocoolers in cryopreservation equipment, expects to significantly improve the distribution of live vaccines in territories where liquid nitrogen is not readily available and the supply of electricity is unreliable."
Asymptote's current low-volume liquid nitrogen-free cryocooler, the EF600-controlled rate freezer, consists of a low-cost, ultra-portable cryocooler, specifically designed for the cryopreservation of stem cells, embryos, and spermatozoa. It demonstrates a high level of cooling rate control accuracy, while simultaneously being simple and easy to handle. It supports numerous sample formats and enables the lab technician to work with linear as well as non-linear cooling profiles.
As EF600s do not require liquid nitrogen, the running costs are estimated to be one per cent of that of liquid nitrogen-controlled rate freezing. By not using liquid nitrogen and its detrimental effects on sterility, particulate generation, and oxygen depletion, the solution is ideal for use in Grade B clean rooms and can be adapted for use in operating rooms for the optimised cryopreservation of source material for autologous treatments.
The new VIA Freeze™ range of controlled rate freezers are designed to be very easy to use with a touch screen interface and remote access (with 21 CRF 11 compliance) can be used with the SBS plate standards from 1-4 plates. This allows users to easily program and upload cooling profiles for further validation and report generation. Furthermore designed to minimise temperature gradients, the VIA Freeze™ achieves precision control of the cooling rate and the temperature. The systems can also be adapted to be used with bespoke systems and automation if required. Since Asymptote's cryogenic solutions (controlled rate freezers and long term storage solutions) do not use liquid nitrogen they do not require the liquid nitrogen infrastructure and the associated health and safety systems required by other systems or the ongoing liquid nitrogen running costs and possibilities of contamination from liquid nitrogen.
The VIA Freeze™ enables the cryopreservation of cells in different formats such as cryovials, cryobags and cassettes. With a capacity of 250 cryovials, the VIA Freeze™ represents the best option for the creation of seed cell banks (SCBs) and master cell banks (MCBs), which require validated, reproducible, and safe methods of freezing cells during their creation.
Asymptote has also developed a novel active nucleation biocompatible material named 'IceStart™' that helps to reduce the damage caused by supercooling during the cryopreservation process. Compared to other products in the market, IceStart™ induces ice nucleation closer to the freezing point of the solution. This results in an important reduction in the number of samples that are subjected to extreme undercooling. Consequently the viability of the cells is substantially increased.
Asymptote's research in cryopreservation is based on five principal projects - the development of a GMP cryogenic cold chain for the clinical delivery of regenerative medicine therapeutics; the development of coatings that induce ice nucleation; an improved method of freeze drying; the development of a portable, self-charging cryogenic vessel for the shipment and short-term storage of cryopreserved material; and the development and testing of technology for the cryopreservation of hepatocytes in microtiter plates for subsequent screening applications. These projects are carried out in collaboration with its customers, in order to continuously improve their results and ensure that their needs are met.
"The company is currently proposing the development of the first GMP-compliant cryogenic cold chain for the clinical delivery of regenerative medicine therapeutics. Asymptote is also developing an ice-nucleating coating for the inside of vessels that are used for cryopreservation, which will overcome the problems caused by random ice nucleation and improve cell recovery upon thawing," noted Van Cauwenberghe. "The company expects to determine the real impact of these new developments in the market, as well as their disruptive influence on an existing solution or the creation of new products."
Each year, Frost & Sullivan presents this award to the company that has demonstrated uniqueness in developing and leveraging new technologies, which significantly impacts both the functionality and the customer value of the new products and applications. The award lauds the high R&D spend towards innovation, its relevance to the industry and the positive impact on brand perception.
Frost & Sullivan Best Practices awards recognize companies in a variety of regional and global markets for demonstrating outstanding achievement and superior performance in areas such as leadership, technological innovation, customer service and strategic product development. Industry analysts compare market participants and measure performance through in-depth interviews, analysis and extensive secondary research to identify best practices in the industry.
About Asymptote Limited
Based in Cambridge, UK, Asymptote Limited is excelling in the development of products and process technologies that are adapted to its customers' requirements. Having on board laureate cryopreservation specialists, Asymptote is innovating the cryopreservation market by providing novel, effective, and environment friendly solutions.
About Frost & Sullivan
Frost & Sullivan, the Growth Partnership Company, works in collaboration with clients to leverage visionary innovation that addresses the global challenges and related growth opportunities that will make or break today's market participants.
Our "Growth Partnership" supports clients by addressing these opportunities and incorporating two key elements driving visionary innovation: The Integrated Value Proposition and The Partnership Infrastructure.
- The Integrated Value Proposition provides support to our clients throughout all phases of their journey to visionary innovation including: research, analysis, strategy, vision, innovation and implementation.
- The Partnership Infrastructure is entirely unique as it constructs the foundation upon which visionary innovation becomes possible. This includes our 360 degree research, comprehensive industry coverage, career best practices as well as our global footprint of more than 40 offices.
For more than 50 years, we have been developing growth strategies for the global 1000, emerging businesses, the public sector and the investment community. Is your organization prepared for the next profound wave of industry convergence, disruptive technologies, increasing competitive intensity, Mega Trends, breakthrough best practices, changing customer dynamics and emerging economies?
Best Practices, Frost & Sullivan
E: [email protected]
P: +44 (0) 207 915 7867
Big Data, cloud, analytics, contextual information, wearable tech, sensors, mobility, and WebRTC: together, these advances have created a perfect storm of technologies that are disrupting and transforming classic communications models and ecosystems. In his session at @ThingsExpo, Erik Perotti, Senior Manager of New Ventures on Plantronics’ Innovation team, provided an overview of this technological shift, including associated business and consumer communications impacts, and opportunities it m...
Feb. 25, 2017 06:00 PM EST Reads: 7,680
With billions of sensors deployed worldwide, the amount of machine-generated data will soon exceed what our networks can handle. But consumers and businesses will expect seamless experiences and real-time responsiveness. What does this mean for IoT devices and the infrastructure that supports them? More of the data will need to be handled at - or closer to - the devices themselves.
Feb. 25, 2017 05:45 PM EST Reads: 2,207
When you focus on a journey from up-close, you look at your own technical and cultural history and how you changed it for the benefit of the customer. This was our starting point: too many integration issues, 13 SWP days and very long cycles. It was evident that in this fast-paced industry we could no longer afford this reality. We needed something that would take us beyond reducing the development lifecycles, CI and Agile methodologies. We made a fundamental difference, even changed our culture...
Feb. 25, 2017 05:45 PM EST Reads: 2,929
Updating DevOps to the latest production data slows down your development cycle. Probably it is due to slow, inefficient conventional storage and associated copy data management practices. In his session at @DevOpsSummit at 20th Cloud Expo, Dhiraj Sehgal, in Product and Solution at Tintri, will talk about DevOps and cloud-focused storage to update hundreds of child VMs (different flavors) with updates from a master VM in minutes, saving hours or even days in each development cycle. He will also...
Feb. 25, 2017 05:15 PM EST Reads: 2,678
Things are changing so quickly in IoT that it would take a wizard to predict which ecosystem will gain the most traction. In order for IoT to reach its potential, smart devices must be able to work together. Today, there are a slew of interoperability standards being promoted by big names to make this happen: HomeKit, Brillo and Alljoyn. In his session at @ThingsExpo, Adam Justice, vice president and general manager of Grid Connect, will review what happens when smart devices don’t work togethe...
Feb. 25, 2017 05:00 PM EST Reads: 1,513
SYS-CON Events announced today that Dataloop.IO, an innovator in cloud IT-monitoring whose products help organizations save time and money, has been named “Bronze Sponsor” of SYS-CON's 20th International Cloud Expo®, which will take place on June 6-8, 2017, at the Javits Center in New York City, NY. Dataloop.IO is an emerging software company on the cutting edge of major IT-infrastructure trends including cloud computing and microservices. The company, founded in the UK but now based in San Fran...
Feb. 25, 2017 05:00 PM EST Reads: 2,931
A strange thing is happening along the way to the Internet of Things, namely far too many devices to work with and manage. It has become clear that we'll need much higher efficiency user experiences that can allow us to more easily and scalably work with the thousands of devices that will soon be in each of our lives. Enter the conversational interface revolution, combining bots we can literally talk with, gesture to, and even direct with our thoughts, with embedded artificial intelligence, whic...
Feb. 25, 2017 04:45 PM EST Reads: 1,734
SYS-CON Events announced today that Addteq will exhibit at SYS-CON's @DevOpsSummit at Cloud Expo New York, which will take place on June 6-8, 2017, at the Javits Center in New York City, NY. Addteq is one of the top 10 Platinum Atlassian Experts who specialize in DevOps, custom and continuous integration, automation, plugin development, and consulting for midsize and global firms. Addteq firmly believes that automation is essential for successful software releases. Addteq centers its products an...
Feb. 25, 2017 04:30 PM EST Reads: 337
Some people worry that OpenStack is more flash then substance; however, for many customers this could not be farther from the truth. No other technology equalizes the playing field between vendors while giving your internal teams better access than ever to infrastructure when they need it. In his session at 20th Cloud Expo, Chris Brown, a Solutions Marketing Manager at Nutanix, will talk through some real-world OpenStack deployments and look into the ways this can benefit customers of all sizes....
Feb. 25, 2017 04:30 PM EST Reads: 1,444
In his session at @ThingsExpo, Sudarshan Krishnamurthi, a Senior Manager, Business Strategy, at Cisco Systems, will discuss how IT and operational technology (OT) work together, as opposed to being in separate siloes as once was traditional. Attendees will learn how to fully leverage the power of IoT in their organization by bringing the two sides together and bridging the communication gap. He will also look at what good leadership must entail in order to accomplish this, and how IT managers ca...
Feb. 25, 2017 04:15 PM EST Reads: 1,813
DevOps is being widely accepted (if not fully adopted) as essential in enterprise IT. But as Enterprise DevOps gains maturity, expands scope, and increases velocity, the need for data-driven decisions across teams becomes more acute. DevOps teams in any modern business must wrangle the ‘digital exhaust’ from the delivery toolchain, "pervasive" and "cognitive" computing, APIs and services, mobile devices and applications, the Internet of Things, and now even blockchain.
Feb. 25, 2017 04:15 PM EST Reads: 1,767
SYS-CON Events announced today that CA Technologies has been named “Platinum Sponsor” of SYS-CON's 20th International Cloud Expo®, which will take place on June 6-8, 2017, at the Javits Center in New York City, NY, and the 21st International Cloud Expo®, which will take place October 31-November 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA. CA Technologies helps customers succeed in a future where every business – from apparel to energy – is being rewritten by software. From ...
Feb. 25, 2017 03:30 PM EST Reads: 2,488
In his keynote at 18th Cloud Expo, Andrew Keys, Co-Founder of ConsenSys Enterprise, provided an overview of the evolution of the Internet and the Database and the future of their combination – the Blockchain. Andrew Keys is Co-Founder of ConsenSys Enterprise. He comes to ConsenSys Enterprise with capital markets, technology and entrepreneurial experience. Previously, he worked for UBS investment bank in equities analysis. Later, he was responsible for the creation and distribution of life settle...
Feb. 25, 2017 03:30 PM EST Reads: 1,585
Building a cross-cloud operational model can be a daunting task. Per-cloud silos are not the answer, but neither is a fully generic abstraction plane that strips out capabilities unique to a particular provider. In his session at 20th Cloud Expo, Chris Wolf, VP & Chief Technology Officer, Global Field & Industry at VMware, will discuss how successful organizations approach cloud operations and management, with insights into where operations should be centralized and when it’s best to decentraliz...
Feb. 25, 2017 03:15 PM EST Reads: 2,000
TechTarget storage websites are the best online information resource for news, tips and expert advice for the storage, backup and disaster recovery markets. By creating abundant, high-quality editorial content across more than 140 highly targeted technology-specific websites, TechTarget attracts and nurtures communities of technology buyers researching their companies' information technology needs. By understanding these buyers' content consumption behaviors, TechTarget creates the purchase inte...
Feb. 25, 2017 02:30 PM EST Reads: 1,740