Click here to close now.




















Welcome!

News Feed Item

Van Andel Research Institute Expands its Parkinson's Disease Program with the Addition of Two Groundbreaking Scientists

Biomedical research institute appoints two key positions, expanding its impact on neurodegenerative science

GRAND RAPIDS, Mich., March 26, 2014 /PRNewswire/ -- Van Andel Research Institute's Center for Neurodegenerative Science continues to expand its research portfolio and increase its impact in the field of Parkinson's disease research. The Center recently appointed Dr. Jiyan Ma, whose laboratory studies prions, the misfolded proteins associated with many contagious neurodegenerative diseases, and Dr. Darren Moore, who studies the role of the LRRK2 gene found in hereditary Parkinson's disease. These two accomplished scientists are focused on specific, nuanced areas of Parkinson's disease research that have far-reaching implications for the way the disease is viewed and treated. 

A native of Shanghai, Ma attended Shanghai Medical College and received his Ph.D. at the University of Illinois at Chicago.  As professor and head of the Laboratory of Prion Mechanisms in Neurodegeneration at Van Andel Research Institute, Ma aims to develop disease-modifying therapeutics that combat the degenerative qualities of Parkinson's disease. His research also focuses on how misfolded proteins like alpha-synuclein are linked to the spread of Parkinson's disease in the brain, and the relationship between prions and other neurodegenerative diseases such as Alzheimer's and amyotrophic lateral sclerosis (ALS).

Ma's previous research delved into prions' role in contagious neurodegenerative diseases such as bovine spongiform encephalopathy (mad cow disease) and its human variant, Creutzfeldt-Jakob disease. Ma shares the emerging view that there is a connection between the way prions spread contagious neurodegenerative diseases and how they propagate Parkinson's disease within the human brain.

Like Ma, Dr. Darren Moore is studying a very significant yet specialized area of Parkinson's disease. Moore's research is centered on a gene called leucine-rich repeat kinase 2 (LRRK2) and its role in hereditary Parkinson's disease.

Moore's research will continue to focus on investigating gene products associated with inherited forms of Parkinson's disease, including the LRRK2 as well as other novel genes associated with the disease. His lab plans on utilizing a series of unique disease modeling strategies to better understand how these specific proteins contribute to neurodegeneration in the human brain.

Since its creation in 2011, the Center has experienced impressive growth under Brundin's leadership. Ma and Moore's targeted approaches to neurodegenerative disease research will enhance the portfolio of Van Andel Research Institute's Center for Neurodegenerative Science and provide fertile ground for the development of new, innovative therapeutics for Parkinson's disease.

Van Andel Research Institute

Established by Jay and Betty Van Andel in 1996, Van Andel Institute (VAI) is an independent research and educational organization based in Grand Rapids, Mich. Van Andel Research Institute (VARI), VAI's research arm, is dedicated to studying the genetic, cellular and molecular origins of cancer, Parkinson's and other diseases and working to translate those findings into effective therapies. Find out more about Van Andel Institute or donate by visiting www.vai.org.

CONTACT: Frank Adam Brenner
Communications & Marketing Associate II
Van Andel Institute
[email protected]
616.234.5809
Cell: 773.615.1630

SOURCE Van Andel Research Institute

More Stories By PR Newswire

Copyright © 2007 PR Newswire. All rights reserved. Republication or redistribution of PRNewswire content is expressly prohibited without the prior written consent of PRNewswire. PRNewswire shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.

Latest Stories
"We got started as search consultants. On the services side of the business we have help organizations save time and save money when they hit issues that everyone more or less hits when their data grows," noted Otis Gospodnetić, Founder of Sematext, in this SYS-CON.tv interview at @DevOpsSummit, held June 9-11, 2015, at the Javits Center in New York City.
The speed of software changes in growing and large scale rapid-paced DevOps environments presents a challenge for continuous testing. Many organizations struggle to get this right. Practices that work for small scale continuous testing may not be sufficient as the requirements grow. In his session at DevOps Summit, Marc Hornbeek, Sr. Solutions Architect of DevOps continuous test solutions at Spirent Communications, explained the best practices of continuous testing at high scale, which is rele...
"We have been in business for 21 years and have been building many enterprise solutions, all IT plumbing - server, storage, interconnects," stated Alex Gorbachev, President of Intelligent Systems Services, in this SYS-CON.tv interview at 16th Cloud Expo, held June 9-11, 2015, at the Javits Center in New York City.
In a recent research, analyst firm IDC found that the average cost of a critical application failure is $500,000 to $1 million per hour and the average total cost of unplanned application downtime is $1.25 billion to $2.5 billion per year for Fortune 1000 companies. In addition to the findings on the cost of the downtime, the research also highlighted best practices for development, testing, application support, infrastructure, and operations teams.
"We specialize in testing. DevOps is all about continuous delivery and accelerating the delivery pipeline and there is no continuous delivery without testing," noted Marc Hornbeek, Sr. Solutions Architect at Spirent Communications, in this SYS-CON.tv interview at @DevOpsSummit, held June 9-11, 2015, at the Javits Center in New York City.
How do you securely enable access to your applications in AWS without exposing any attack surfaces? The answer is usually very complicated because application environments morph over time in response to growing requirements from your employee base, your partners and your customers. In his session at @DevOpsSummit, Haseeb Budhani, CEO and Co-founder of Soha, shared five common approaches that DevOps teams follow to secure access to applications deployed in AWS, Azure, etc., and the friction an...
"Alert Logic is a managed security service provider that basically deploys technologies, but we support those technologies with the people and process behind it," stated Stephen Coty, Chief Security Evangelist at Alert Logic, in this SYS-CON.tv interview at 16th Cloud Expo, held June 9-11, 2015, at the Javits Center in New York City.
Digital Transformation is the ultimate goal of cloud computing and related initiatives. The phrase is certainly not a precise one, and as subject to hand-waving and distortion as any high-falutin' terminology in the world of information technology. Yet it is an excellent choice of words to describe what enterprise IT—and by extension, organizations in general—should be working to achieve. Digital Transformation means: handling all the data types being found and created in the organizat...
The essence of cloud computing is that all consumable IT resources are delivered as services. In his session at 15th Cloud Expo, Yung Chou, Technology Evangelist at Microsoft, demonstrated the concepts and implementations of two important cloud computing deliveries: Infrastructure as a Service (IaaS) and Platform as a Service (PaaS). He discussed from business and technical viewpoints what exactly they are, why we care, how they are different and in what ways, and the strategies for IT to tran...
The Internet of Everything (IoE) brings together people, process, data and things to make networked connections more relevant and valuable than ever before – transforming information into knowledge and knowledge into wisdom. IoE creates new capabilities, richer experiences, and unprecedented opportunities to improve business and government operations, decision making and mission support capabilities.
The Software Defined Data Center (SDDC), which enables organizations to seamlessly run in a hybrid cloud model (public + private cloud), is here to stay. IDC estimates that the software-defined networking market will be valued at $3.7 billion by 2016. Security is a key component and benefit of the SDDC, and offers an opportunity to build security 'from the ground up' and weave it into the environment from day one. In his session at 16th Cloud Expo, Reuven Harrison, CTO and Co-Founder of Tufin,...
The Internet of Things is not only adding billions of sensors and billions of terabytes to the Internet. It is also forcing a fundamental change in the way we envision Information Technology. For the first time, more data is being created by devices at the edge of the Internet rather than from centralized systems. What does this mean for today's IT professional? In this Power Panel at @ThingsExpo, moderated by Conference Chair Roger Strukhoff, panelists addressed this very serious issue of pro...
Container technology is sending shock waves through the world of cloud computing. Heralded as the 'next big thing,' containers provide software owners a consistent way to package their software and dependencies while infrastructure operators benefit from a standard way to deploy and run them. Containers present new challenges for tracking usage due to their dynamic nature. They can also be deployed to bare metal, virtual machines and various cloud platforms. How do software owners track the usag...
With SaaS use rampant across organizations, how can IT departments track company data and maintain security? More and more departments are commissioning their own solutions and bypassing IT. A cloud environment is amorphous and powerful, allowing you to set up solutions for all of your user needs: document sharing and collaboration, mobile access, e-mail, even industry-specific applications. In his session at 16th Cloud Expo, Shawn Mills, President and a founder of Green House Data, discussed h...
Discussions about cloud computing are evolving into discussions about enterprise IT in general. As enterprises increasingly migrate toward their own unique clouds, new issues such as the use of containers and microservices emerge to keep things interesting. In this Power Panel at 16th Cloud Expo, moderated by Conference Chair Roger Strukhoff, panelists addressed the state of cloud computing today, and what enterprise IT professionals need to know about how the latest topics and trends affect t...