Welcome!

News Feed Item

Van Andel Research Institute Expands its Parkinson's Disease Program with the Addition of Two Groundbreaking Scientists

Biomedical research institute appoints two key positions, expanding its impact on neurodegenerative science

GRAND RAPIDS, Mich., March 26, 2014 /PRNewswire/ -- Van Andel Research Institute's Center for Neurodegenerative Science continues to expand its research portfolio and increase its impact in the field of Parkinson's disease research. The Center recently appointed Dr. Jiyan Ma, whose laboratory studies prions, the misfolded proteins associated with many contagious neurodegenerative diseases, and Dr. Darren Moore, who studies the role of the LRRK2 gene found in hereditary Parkinson's disease. These two accomplished scientists are focused on specific, nuanced areas of Parkinson's disease research that have far-reaching implications for the way the disease is viewed and treated. 

A native of Shanghai, Ma attended Shanghai Medical College and received his Ph.D. at the University of Illinois at Chicago.  As professor and head of the Laboratory of Prion Mechanisms in Neurodegeneration at Van Andel Research Institute, Ma aims to develop disease-modifying therapeutics that combat the degenerative qualities of Parkinson's disease. His research also focuses on how misfolded proteins like alpha-synuclein are linked to the spread of Parkinson's disease in the brain, and the relationship between prions and other neurodegenerative diseases such as Alzheimer's and amyotrophic lateral sclerosis (ALS).

Ma's previous research delved into prions' role in contagious neurodegenerative diseases such as bovine spongiform encephalopathy (mad cow disease) and its human variant, Creutzfeldt-Jakob disease. Ma shares the emerging view that there is a connection between the way prions spread contagious neurodegenerative diseases and how they propagate Parkinson's disease within the human brain.

Like Ma, Dr. Darren Moore is studying a very significant yet specialized area of Parkinson's disease. Moore's research is centered on a gene called leucine-rich repeat kinase 2 (LRRK2) and its role in hereditary Parkinson's disease.

Moore's research will continue to focus on investigating gene products associated with inherited forms of Parkinson's disease, including the LRRK2 as well as other novel genes associated with the disease. His lab plans on utilizing a series of unique disease modeling strategies to better understand how these specific proteins contribute to neurodegeneration in the human brain.

Since its creation in 2011, the Center has experienced impressive growth under Brundin's leadership. Ma and Moore's targeted approaches to neurodegenerative disease research will enhance the portfolio of Van Andel Research Institute's Center for Neurodegenerative Science and provide fertile ground for the development of new, innovative therapeutics for Parkinson's disease.

Van Andel Research Institute

Established by Jay and Betty Van Andel in 1996, Van Andel Institute (VAI) is an independent research and educational organization based in Grand Rapids, Mich. Van Andel Research Institute (VARI), VAI's research arm, is dedicated to studying the genetic, cellular and molecular origins of cancer, Parkinson's and other diseases and working to translate those findings into effective therapies. Find out more about Van Andel Institute or donate by visiting www.vai.org.

CONTACT: Frank Adam Brenner
Communications & Marketing Associate II
Van Andel Institute
[email protected]
616.234.5809
Cell: 773.615.1630

SOURCE Van Andel Research Institute

More Stories By PR Newswire

Copyright © 2007 PR Newswire. All rights reserved. Republication or redistribution of PRNewswire content is expressly prohibited without the prior written consent of PRNewswire. PRNewswire shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.

Latest Stories
Cloud adoption is often driven by a desire to increase efficiency, boost agility and save money. All too often, however, the reality involves unpredictable cost spikes and lack of oversight due to resource limitations. In his session at 20th Cloud Expo, Joe Kinsella, CTO and Founder of CloudHealth Technologies, tackled the question: “How do you build a fully optimized cloud?” He will examine: Why TCO is critical to achieving cloud success – and why attendees should be thinking holistically ab...
SYS-CON Events announced today that Grape Up will exhibit at SYS-CON's 21st International Cloud Expo®, which will take place on Oct. 31 – Nov 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA. Grape Up is a software company specializing in cloud native application development and professional services related to Cloud Foundry PaaS. With five expert teams that operate in various sectors of the market across the U.S. and Europe, Grape Up works with a variety of customers from emergi...
As DevOps methodologies expand their reach across the enterprise, organizations face the daunting challenge of adapting related cloud strategies to ensure optimal alignment, from managing complexity to ensuring proper governance. How can culture, automation, legacy apps and even budget be reexamined to enable this ongoing shift within the modern software factory?
SYS-CON Events announced today that Elastifile will exhibit at SYS-CON's 21st International Cloud Expo®, which will take place on Oct 31 - Nov 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA. Elastifile Cloud File System (ECFS) is software-defined data infrastructure designed for seamless and efficient management of dynamic workloads across heterogeneous environments. Elastifile provides the architecture needed to optimize your hybrid cloud environment, by facilitating efficient...
SYS-CON Events announced today that Grape Up will exhibit at SYS-CON's 21st International Cloud Expo®, which will take place on Oct. 31 – Nov 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA. Grape Up is a software company specializing in cloud native application development and professional services related to Cloud Foundry PaaS. With five expert teams that operate in various sectors of the market across the U.S. and Europe, Grape Up works with a variety of customers from emergi...
@DevOpsSummit at Cloud Expo taking place Oct 31 - Nov 2, 2017, at the Santa Clara Convention Center, Santa Clara, CA, is co-located with the 21st International Cloud Expo and will feature technical sessions from a rock star conference faculty and the leading industry players in the world. The widespread success of cloud computing is driving the DevOps revolution in enterprise IT. Now as never before, development teams must communicate and collaborate in a dynamic, 24/7/365 environment. There is ...
SYS-CON Events announced today that Golden Gate University will exhibit at SYS-CON's 21st International Cloud Expo®, which will take place on Oct 31 – Nov 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA. Since 1901, non-profit Golden Gate University (GGU) has been helping adults achieve their professional goals by providing high quality, practice-based undergraduate and graduate educational programs in law, taxation, business and related professions. Many of its courses are taug...
DevOps at Cloud Expo, taking place October 31 - November 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA, is co-located with 21st Cloud Expo and will feature technical sessions from a rock star conference faculty and the leading industry players in the world. The widespread success of cloud computing is driving the DevOps revolution in enterprise IT. Now as never before, development teams must communicate and collaborate in a dynamic, 24/7/365 environment. There is no time to w...
When shopping for a new data processing platform for IoT solutions, many development teams want to be able to test-drive options before making a choice. Yet when evaluating an IoT solution, it’s simply not feasible to do so at scale with physical devices. Building a sensor simulator is the next best choice; however, generating a realistic simulation at very high TPS with ease of configurability is a formidable challenge. When dealing with multiple application or transport protocols, you would be...
Given the popularity of the containers, further investment in the telco/cable industry is needed to transition existing VM-based solutions to containerized cloud native deployments. The networking architecture of the solution isolates the network traffic into different network planes (e.g., management, control, and media). This naturally makes support for multiple interfaces in container orchestration engines an indispensable requirement.
With Cloud Foundry you can easily deploy and use apps utilizing websocket technology, but not everybody realizes that scaling them out is not that trivial. In his session at 21st Cloud Expo, Roman Swoszowski, CTO and VP, Cloud Foundry Services, at Grape Up, will show you an example of how to deal with this issue. He will demonstrate a cloud-native Spring Boot app running in Cloud Foundry and communicating with clients over websocket protocol that can be easily scaled horizontally and coordinate...
yperConvergence came to market with the objective of being simple, flexible and to help drive down operating expenses. It reduced the footprint by bundling the compute/storage/network into one box. This brought a new set of challenges as the HyperConverged vendors are very focused on their own proprietary building blocks. If you want to scale in a certain way, let’s say you identified a need for more storage and want to add a device that is not sold by the HyperConverged vendor, forget about it....
21st International Cloud Expo, taking place October 31 - November 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA, will feature technical sessions from a rock star conference faculty and the leading industry players in the world. Cloud computing is now being embraced by a majority of enterprises of all sizes. Yesterday's debate about public vs. private has transformed into the reality of hybrid cloud: a recent survey shows that 74% of enterprises have a hybrid cloud strategy. Me...
DevOps at Cloud Expo, taking place October 31 - November 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA, is co-located with 21st Cloud Expo and will feature technical sessions from a rock star conference faculty and the leading industry players in the world. The widespread success of cloud computing is driving the DevOps revolution in enterprise IT. Now as never before, development teams must communicate and collaborate in a dynamic, 24/7/365 environment. There is no time to w...
Vulnerability management is vital for large companies that need to secure containers across thousands of hosts, but many struggle to understand how exposed they are when they discover a new high security vulnerability. In his session at 21st Cloud Expo, John Morello, CTO of Twistlock, will address this pressing concern by introducing the concept of the “Vulnerability Risk Tree API,” which brings all the data together in a simple REST endpoint, allowing companies to easily grasp the severity of t...