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DNA Sequencing: Emerging Technologies and Applications

LONDON, April 17, 2014 /PRNewswire/ -- Reportbuyer.com has added a new market research report:

DNA Sequencing: Emerging Technologies and Applications

http://www.reportbuyer.com/pharma_healthcare/biotechnology/technologies/dna_sequencing_emerging_technologies_applications.html

REPORT HIGHLIGHTS

The global market for sequencing products and services reached $3.5 billion in 2012. This market is expected to grow to nearly $4.5 billion in 2013 and nearly 11.7 billion in 2018, a compound annual growth rate (CAGR) of 21.2%.

This report provides:
An overview of the global market for sequencing products and services.
Analyses of global market trends, with data from 2012, estimates for 2013, and projections of compound annual growth rates (CAGRs) through 2018.
Quantification of the DNA sequencing markets by product type, platform, customer type,value chain position, analysis type and geography.
A look at substantial future growth opportunities for industry participants including consumer and diagnostic sequencing services, bioinformatics, sequence enrichment, benchtop NGS sequencers and consumables, and emerging sequencing instruments.

STUDY GOALS AND OBJECTIVES

BCC Research's goal for this study is to provide an in-depth analysis of the sequencing industry, an important industry in life sciences with enormous market potential. The approach for analyzing the industry is taken in terms of workflow (e.g., sequencers, sequence capture, informatics) and key applications (e.g., research, applied, services, sample prep, informatics) where sequencing will have market share by 2018.BCC Research examines the markets for sequencing products and services for the years 2012, 2013 and 2018.Special emphasis is placed on the global next-generation sequencing (NGS) diagnostic markets, which are characterized and quantified by disease indication, test complexity, test purpose and geography.Sequencing market segments that provide exciting growth opportunities include benchtop NGS sequencing instruments and consumables; clinical diagnostics (e.g., cancer, rare genetic diseases and prenatal screening); sequencing software; and consumer sequencing services.The report provides a comprehensive discussion of sequencing technologies, market applications, industry structure, important clinical sequencing initiatives, global markets, patent status and companies. The report is designed to aid companies in their strategic planning efforts for accessing sequencing industry opportunities.

REASONS FOR DOING THE STUDY

The Human Genome Project (HGP) moved DNA sequencing technology to the forefront of life science research as a genetic analysis tool. The HGP relied heavily on Sanger sequencing by capillary electrophoresis to decipher the DNA sequence of the bases in the human genome.The HGP led to significant improvements in the efficiency and costs of DNA sequencing. During this time period, the sequencing industry consolidated, resulting in one dominant company, Applied Biosystems (now Life Technologies).Beginning in 2005, the launch of next-generation sequencing technologies radically changed the structure of the industry and opened up exciting new market applications. The costs of sequencing have rapidly reduced to the point where it is now feasible for complex NGS tests to be priced in the range of other multiplex genetic tests.As a result, opportunities for sequencing products and services are emerging in diverse applications ranging, for example, from clinical diagnostics to direct to consumer genetic testing markets.Clinical value has been shown for many applications, and several launched tests are having good commercial success. This shows that both patients and physicians are recognizing the value of NGS tests. Several molecular genetic tests that have been successful on non-NGS formats will run on NGS platforms in the future.At the same time, payors and insurance companies are beginning to provide coverage for these tests, further enhancing their commercial potential.In direct to consumer genetic testing market, there is an emerging trend to move to sequencing of specific genome regions. Compared with microarrays, sequencing provides more comprehensive information to the consumer. Recent product introductions by Full Genomes Corporation and Family Tree DNA using NGS to sequence the full Y chromosome are examples of this trend.These technical and market factors are driving this market so that it is now timely to examine the sequencing markets.

INTENDED AUDIENCE

This report fills a gap in market research as it covers the three main sequencing platforms: Sanger sequencing, NGS and 3GS.The report provides a roadmap for understanding where sequencing is likely to be used in the life sciences during the next five years. As such, it is a useful guide for strategic and business planning, as well as for learning about the impact new sequencing technologies will have in the various market segments.This market report will be useful to many companies involved in the direct to consumer, informatics, clinical, genetic testing and sequencing industries. It will be particularly valuable for companies in such industries as life science research tools, NGS instruments, molecular diagnostics, informatics, clinical laboratories, pharmaceutical, biotechnology, microfluidics, lab-on-a-chip and sample preparation.

SCOPE AND FORMAT

The scope of the report includes sequencing technologies, applications, industries, initiatives, markets, patents and companies. The markets for sequencing products and services are given for the years 2012, 2013 and 2018.This report reviews the main sequencing platforms, and explains why genetic variation is important for many markets, including clinical testing. It then discusses some of the top research initiatives that are contributing to NGS applications. Market driving forces are also discussed.The report covers the sequencing markets by workflow, including sample preparation products; sequencing instruments & consumables; informatics; and sequencing services. It includes the sequencing instrument market by platform: Sanger, NGS and 3GS and by instrument class: low throughput, high-throughput, benchtop, and handheld.The report covers the markets for the main sequencing end use applications, including research (R&D, drug discovery & development, biotech); clinical; consumer; and applied (forensics, microbial genomics, agricultural genomics).A key part of the report covers NGS clinical markets in depth, including by test complexity, indication and test purpose. Test complexity refers to the multiplexing (e.g., the number of genes covered) and coverage (e.g., the extent to which the genome is covered) of the test. Examining the market by test complexity provides valuable insight into which products (e.g., sample preparation, NGS instrument, informatics) will be in demand in the future.The report provides market data and forecasts for NGS diagnostics by specific applications, including those for cancer, rare diseases, common diseases, and pre- and post-natal screening.Specific geographic markets are discussed, including North America, Europe, China, Japan and the rest of the world.Market data covers the years 2012, 2013 and 2018.Industry sectors analyzed in this report include NGS instruments (including market share data for the main instrument companies); NGS target enrichment; 3GS; direct to consumer genetic testing; single cell genomics; NGS-based proteomics; informatics; information technology; clinical laboratory; and the prenatal diagnostics (including market shares for the leading NGS companies).More than 142 companies in the sequencing industry are profiled in this report.BCC Research provides a summary of the main industry acquisitions and strategic alliances from 2011 through 2013, including key alliance trends.

METHODOLOGY

Both primary and secondary research methodologies were used in preparing this study. BCC Research examined each of the key end-user market segments that will be commercially important during the next five years.Based on this analysis, the current and future applications of sequencing technologies are evaluated in each of the major market segments and sales revenues are forecast for 2013 through 2018.Based on analysis of both secondary and primary market sources, as well as the key trends in the industry, the report provides the current and projected market size for the various sequencing market segments for the years 2012, 2013 and 2018.
Chapter- 1: INTRODUCTION
STUDY GOALS AND OBJECTIVES
REASONS FOR DOING THE STUDY
INTENDED AUDIENCE
SCOPE AND FORMAT
METHODOLOGY
INFORMATION SOURCES
RELATED BCC RESEARCH REPORTS
ANALYST CREDENTIALS
BCC RESEARCH ONLINE SERVICES
DISCLAIMER
Chapter- 2: EXECUTIVE SUMMARY
Table Summary : GLOBAL VALUE OF SEQUENCING PRODUCTS AND SERVICES, BY TYPE, THROUGH 2018
Figure Summary : GLOBAL VALUE OF SEQUENCING PRODUCTS AND SERVICES, BY TYPE, 2012–2018
Chapter- 3: OVERVIEW
INTRODUCTION
SEQUENCING MARKET
SEQUENCING PRODUCTS
SEQUENCING PRODUCT LIFE CYCLE STATUS
NEXT-GENERATION SEQUENCING INDUSTRY
Chapter- 4: TECHNOLOGIES
IMPORTANCE OF DNA
GENETIC VARIATION AND ANALYSIS
GENETIC ANALYSIS TECHNOLOGIES
SEQUENCING IN CLINICAL APPLICATIONS
SEQUENCING TECHNOLOGIES
INFORMATICS TECHNOLOGIES
CLINICAL SEQUENCING TECHNOLOGY CHALLENGES
TOP TEN CLINICAL NEXT-GENERATION SEQUENCING INITIATIVES
Chapter- 5: DNA SEQUENCING APPLICATIONS
INTRODUCTION
GENETIC ANALYSIS
DE NOVO WHOLE GENOME SEQUENCING
RESEQUENCING
SEQ-BASED METHODS
STRUCTURAL VARIATION STUDIES
COMPLEMENTARY SEQUENCING AND MICROARRAY PLATFORMS
SEQUENCING END-USE APPLICATIONS
Chapter- 6: CLINICAL NEXT-GENERATION SEQUENCING APPLICATIONS
INTRODUCTION
CANCER APPLICATIONS
MENDELIAN DISORDERS APPLICATIONS
SCREENING APPLICATIONS
INFECTIOUS DISEASE APPLICATIONS
COMMON DISORDERS APPLICATIONS
Chapter- 7: SEQUENCING INDUSTRY
INTRODUCTION
NEXT-GENERATION SEQUENCING INSTRUMENT INDUSTRY
NEXT-GENERATION SEQUENCING TARGET ENRICHMENT INDUSTRY
THIRD GENERATION SEQUENCING INDUSTRY
DIRECT-TO-CONSUMER GENETIC TESTING INDUSTRY
SINGLE CELL GENOMICS INDUSTRY
NGS-BASED PROTEOMICS INDUSTRY
SEQUENCING INFORMATICS INDUSTRY
SEQUENCING INFORMATION TECHNOLOGY INDUSTRY
CLINICAL LABORATORY INDUSTRY
PRENATAL DIAGNOSTICS INDUSTRY
SEQUENCING INDUSTRY ACQUISITIONS AND STRATEGIC ALLIANCES
Chapter- 8: SEQUENCING MARKETS
GROWTH DRIVING FORCES
SEQUENCING MARKET SUMMARY
SEQUENCING INSTRUMENTS AND CONSUMABLES MARKET
SEQUENCING SAMPLE PREP MARKETS
SEQUENCING INFORMATICS MARKET
SEQUENCING SERVICES MARKETS
CLINICAL NGS MARKET
CLINICAL NGS CANCER MARKETS
CLINICAL NGS CARDIOVASCULAR MARKETS
CLINICAL NGS MENDELIAN DISORDERS MARKETS
CLINICAL NGS METABOLIC AND IMMUNE DISORDERS MARKETS
CLINICAL NGS NEUROLOGY MARKETS
CLINICAL NGS NEWBORN SCREENING MARKETS
CLINICAL NGS PRENATAL DIAGNOSTIC MARKETS
CLINICAL NGS FOOD-BORNE ILLNESS MARKETS
CLINICAL NGS HUMAN LEUKOCYTE ANTIGEN TYPING MARKETS
SEQUENCING MARKETS BY GEOGRAPHIC REGION
CLINICAL NGS GEOGRAPHICAL MARKETS
Chapter- 9: CLINICAL NGS PATENTS
CLINICAL NEXT-GENERATION SEQUENCING PATENTS BY INDICATION
CLINICAL NEXT-GENERATION SEQUENCING PATENT ISSUES
Table 127 : CLINICAL NEXT-GENERATION SEQUENCING PATENTS*, 2002-2012
Chapter- 10: COMPANY PROFILES
23ANDME INC.
ADAPTIVE BIOTECHNOLOGIES INC.
AGILENT TECHNOLOGIES INC.
ALMAC GROUP LTD.
AMBRY GENETICS
APPISTRY INC.
ASSURERX HEALTH
ASTRID BIOSCIENCE GMBH
ASURAGEN INC.
AVIIR INC.
BASE4 INNOVATION LTD.
BECKMAN COULTER
BERRY GENOMICS CO. LTD.
BGI
BINA TECHNOLOGIES INC.
BLUEPRINT GENETICS
BOREAL GENOMICS
CAMBRIDGE EPIGENETIX LTD.
CARIS LIFE SCIENCES
CEGAT GMBH
CHRONIX BIOMEDICAL
CLC BIO
CODIFIED GENOMICS LLC
CORIELL LIFE SCIENCES INC.
CORRELAGEN DIAGNOSTICS INC
COUNSYL INC
COURTAGEN LIFE SCIENCES INC
CYNVENIO BIOSYSTEMS INC
CYPHER GENOMICS INC.
DIOGENIX INC.
DNA ELECTRONICS LTD.
DNA LINK
DNANEXUS INC.
EAGLE GENOMICS, LTD.
ELECTRONIC BIOSCIENCES
ENZYMATICS INC.
EUROFINS MWG OPERON
EXIQON A/S
EXOSOME DIAGNOSTICS INC.
EXPRESSION ANALYSIS INC.
FOUNDATION MEDICINE
FULL GENOMES CORPORATION
GATC BIOTECH AG
GE HEALTHCARE
GENAPSYS
GENDX BV
GENE BY GENE LTD.
GENEDX INC.
GENEPEEKS INC.
GENEWIZ INC.
GENIA TECHNOLOGIES INC.
GENOLOGICS LIFE SCIENCES SOFTWARE
GENOMATIX SOFTWARE GMBH
GENOMEQUEST INC.
GENOMIC HEALTH INC.
GIGAGEN INC.
GNUBIO INC.
GOOD START GENETICS INC.
ILLUMINA INC.
INGENUITY SYSTEMS INC.
INNOVATIONS EXCHANGE PTE LTD
INVITAE, INC.
IREPERTOIRE
KAILOS GENETICS
KELLBENX INC.
KNOME INC.
LABORATORY CORPORATION OF AMERICA INC.
LABORATORY FOR MOLECULAR MEDICINE
LASERGEN INC.
LIFE TECHNOLOGIES INC.
MACROGEN INC.
MAVERIX BIOMICS INC.
MD ANDERSON CANCER CENTER
MEDGENOME LABS PVT. LTD.
MEDOMICS LLC.
MIINOME INC.
MULTIPLICOM NV
MYRIAD GENETICS INC.
NABSYS INC.
NATERA INC.
NEWGENE LTD.
NOBLEGEN BIOSCIENCES
N-OF-ONE INC.
NOVARTIS AG
NUMERATE INC.
NXT-DX
OMICIA INC.
OMIXON BIOCOMPUTING KFT
ONCODNA SA
ONCOSPIRE GENOMICS
OXFORD GENE TECHNOLOGY
OXFORD NANOPORE TECHNOLOGIES
PACIFIC BIOSCIENCES OF CALIFORNIA INC.
PARABASE GENOMICS
PASTEL BIOSCIENCE LTD
PATHOGENETIX
PATHOGENICA
PATHOQUEST SAS
PERKIN ELMER INC.
PERSONAL GENOME DIAGNOSTICS INC.
PERSONALIS INC.
PICOSEQ
POPULATION GENETICS TECHNOLOGIES LTD.
PORTABLE GENOMICS LLC
PREVENTIONGENETICS INC.
QIAGEN
QUANTUMDX
RAINDANCE TECHNOLOGIES INC.
REAL TIME GENOMICS INC.
REPROGENETICS
RESPONSE GENETICS INC.
ROCHE HOLDING AG
SCIGENOM LABS
SENGENICS INTERNATIONAL PTE LTD.
SEQUENOM INC.
SEQUENTA INC.
SEQUOIA GENETICS CO. LTD.
SEVEN BRIDGES GENOMICS INC.
SIEMENS AG
SILICON VALLEY BIOSYSTEMS
SINGLE CELL TECHNOLOGY, INC.
SISTEMAS GENOMICOS
SOFTGENETICS LLC
SPIRAL GENETICS INC.
STATION X INC.
STRAND LIFE SCIENCES
STRATOS GENOMICS INC.
SUNDANCE DIAGNOSTICS INC.
SYAPSE
SYGNIS AG
SYNAPDX
THERMO FISHER SCIENTIFIC INC.
TRANSGENOMIC INC.
TROVAGENE INC.
TUTE GENOMICS, INC.
TWO PORE GUYS INC.
WARP DRIVE BIO LLC
YIKON GENOMICS CO. LTD.
ZS GENETICS
ZYMO RESEARCH CORPORATION

Read the full report:
DNA Sequencing: Emerging Technologies and Applications

http://www.reportbuyer.com/pharma_healthcare/biotechnology/technologies/dna_sequencing_emerging_technologies_applications.html

For more information:
Sarah Smith
Research Advisor at Reportbuyer.com
Email: [email protected]  
Tel: +44 208 816 85 48
Website: www.reportbuyer.com

SOURCE ReportBuyer

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