|By PR Newswire||
|April 21, 2014 10:34 AM EDT||
KENNEDY SPACE CENTER, Fla., April 21, 2014 /PRNewswire-USNewswire/ -- The Center for the Advancement of Science in Space (CASIS) is proud to announce its research payloads berthed with the International Space Station (ISS) on Sunday, April 20. Space Exploration Technologies Corporation's (SpaceX) Dragon capsule successfully berthed with the ISS, marking the completion of its launch to resupply the ISS with cargo and research. CASIS is tasked with managing and promoting research onboard the ISS U.S. National Laboratory.
Research onboard the SpaceX Dragon capsule included a range of experiments from life sciences. This is the second mission that has been responsible for launching CASIS-sponsored investigations to the ISS. In January, Orbital Sciences Corporation's Cygnus capsule sent the first CASIS-sponsored investigations to the ISS. Below is an overview of the major payloads now onboard the ISS sponsored by CASIS:
Crystalline Monoclonal Antibody
Paul Reichert, Merck Research Laboratories
Commercial investigator Merck will focus on the protein crystal growth of a human monoclonal antibody developed by its research labs that is currently undergoing clinical trials for treatment of an immunological disease. High quality crystalline suspensions of the antibodies in microgravity will aid in not only structure determination but also pharmaceutical applications, such as drug delivery and purification/storage of the therapeutic substance.
IPPase Crystal Growth in Microgravity
Dr. Joseph Ng, iXpressGenes, Inc.
This investigation will produce protein crystals large enough for a specific type of crystallography that can show very intricate details of protein structure. The specific enzyme being studied is involved in a variety of cell functions, including protein production — but a very detailed part of how this enzyme works is unknown. Producing crystals that allow analysis of very small and detailed structural features will not only help researchers understand this protein's function but also determine best practices for studies of other proteins at this level of detail.
Crystallization of Medically Relevant Proteins Using Microgravity
Dr. Sergey Korolev, St. Louis Medical Center
Research on this investigation focuses on improving crystals of two medically important proteins. These two proteins have multiple functions within cells, and results could therefore assist in the development of various medical interventions, from anticoagulant therapies to drug treatments for cardiovascular disease, diabetes, muscular dystrophy and Parkinson's disease.
Exploiting On-Orbit Crystal Properties for Structural Studies of Medically and Economically Important Targets
Dr. Edward Snell, SUNY Buffalo
This research focuses on growing crystals of four proteins associated with human disease. These proteins crystallize on Earth but not with sufficient quality and uniformity to determine their structures. Larger, better-organized crystals of these specific proteins could have a significant impact on drug development for Parkinson's disease, bovine spongiform encephalopathy, ethylmalonic aciduri and cutaneous squamous cell carcinoma.
Crystallization of Huntingtin Exon 1 Using Microgravity
Dr. Pamela Bjorkman, California Institute of Technology
This research focuses huntingtin, the protein responsible for Huntington's disease. The structure of this protein remains unknown. Procuring a high-resolution structure would have significant scientific and medical impact in understanding the structural basis for neural toxicity and developing treatments for Huntington's disease and other related disorders, such as spinocerebellar ataxia.
Crystallization of Human Membrane ABC Proteins in Microgravity
Dr. Stephen Aller, University of Alabama-Birmingham
This investigation focuses on determining the structure of human membrane proteins, which could accelerate the commercialization of next-generation drugs to treat AIDS-related dementia, high cholesterol, atherosclerosis, cystic fibrosis and multi-drug resistance as it relates to cancer.
Molecular Biology of Plant Development in the Spaceflight Environment
Dr. Anna-Lisa Paul, University of Florida
This research focuses on the growth and development of Arabidopsis thaliana seedlings in the spaceflight environment. Researchers seek to identify the genes involved in plant root morphology and adaptive physiology; specifically, how a root knows in which direction to grow when gravity is absent. Results will expand on previous ISS research in this area and inform the study of specific molecular pathways involved in plant adaptive physiology on Earth.
Many of the experiments delivered by the SpaceX Dragon capsule come from the first CASIS-sponsored RFP, "Advancing Protein Crystallization in Microgravity." CASIS believes that through this research, potential therapies can be developed and a baseline for future protein crystal growth experimentation will be established. Additionally, a joint project from NASA, CASIS and the National Institute of Health is onboard, "T-Cell Activation in Aging," in which Dr. Millie Hughes-Fulford will attempt to better understand and develop treatments for disorders of immune suppression by discovering the molecular basis of T-cell suppression in spaceflight.
"Today signifies yet another historic moment for CASIS and our launch partner, SpaceX," said President and Executive Director Gregory H. Johnson. "The research that is now on the ISS has the potential to unlock secrets that could create therapies to improve human health and performance. Additionally, this launch culminates our first official increment period of Advancing Research Knowledge 1. This initial launch period has been instrumental in the further development of CASIS and we look forward to sending additional exciting and innovative research capable of enhancing science in space, for life on Earth."
To learn more about the research destined for the ISS during the first official launch increment period for CASIS, Advancing Research Knowledge 1 (ARK1), please visit: ark1.iss-casis.org
About CASIS: The Center for the Advancement of Science in Space (CASIS) was selected by NASA in July 2011 to maximize use of the International Space Station (ISS) U.S. National Laboratory through 2020. CASIS is dedicated to supporting and accelerating innovations and new discoveries that will enhance the health and wellbeing of people and our planet. For more information, visit www.iss-casis.org.
About the ISS National Laboratory: In 2005, Congress designated the U.S. portion of the International Space Station as the nation's newest national laboratory to maximize its use for improving life on Earth, promoting collaboration among diverse users, and advancing STEM education. This unique laboratory environment is available for use by other U.S. government agencies and by academic and private institutions, providing access to the permanent microgravity setting, vantage point in low Earth orbit, and varied environments of space.
Media Contact: Patrick O'Neill
SOURCE Center for the Advancement of Science in Space
Mobile, social, Big Data, and cloud have fundamentally changed the way we live. “Anytime, anywhere” access to data and information is no longer a luxury; it’s a requirement, in both our personal and professional lives. For IT organizations, this means pressure has never been greater to deliver meaningful services to the business and customers.
Aug. 1, 2015 11:15 AM EDT Reads: 142
Container technology is sending shock waves through the world of cloud computing. Heralded as the 'next big thing,' containers provide software owners a consistent way to package their software and dependencies while infrastructure operators benefit from a standard way to deploy and run them. Containers present new challenges for tracking usage due to their dynamic nature. They can also be deployed to bare metal, virtual machines and various cloud platforms. How do software owners track the usag...
Aug. 1, 2015 10:30 AM EDT Reads: 195
The Internet of Everything (IoE) brings together people, process, data and things to make networked connections more relevant and valuable than ever before – transforming information into knowledge and knowledge into wisdom. IoE creates new capabilities, richer experiences, and unprecedented opportunities to improve business and government operations, decision making and mission support capabilities.
Aug. 1, 2015 10:00 AM EDT Reads: 283
There are many considerations when moving applications from on-premise to cloud. It is critical to understand the benefits and also challenges of this migration. A successful migration will result in lower Total Cost of Ownership, yet offer the same or higher level of robustness. In his session at 15th Cloud Expo, Michael Meiner, an Engineering Director at Oracle, Corporation, analyzed a range of cloud offerings (IaaS, PaaS, SaaS) and discussed the benefits/challenges of migrating to each offe...
Aug. 1, 2015 09:45 AM EDT Reads: 119
Puppet Labs has announced the next major update to its flagship product: Puppet Enterprise 2015.2. This release includes new features providing DevOps teams with clarity, simplicity and additional management capabilities, including an all-new user interface, an interactive graph for visualizing infrastructure code, a new unified agent and broader infrastructure support.
Aug. 1, 2015 09:45 AM EDT Reads: 173
Chuck Piluso presented a study of cloud adoption trends and the power and flexibility of IBM Power and Pureflex cloud solutions. Prior to Secure Infrastructure and Services, Mr. Piluso founded North American Telecommunication Corporation, a facilities-based Competitive Local Exchange Carrier licensed by the Public Service Commission in 10 states, serving as the company's chairman and president from 1997 to 2000. Between 1990 and 1997, Mr. Piluso served as chairman & founder of International Te...
Aug. 1, 2015 09:45 AM EDT Reads: 381
One of the hottest areas in cloud right now is DRaaS and related offerings. In his session at 16th Cloud Expo, Dale Levesque, Disaster Recovery Product Manager with Windstream's Cloud and Data Center Marketing team, will discuss the benefits of the cloud model, which far outweigh the traditional approach, and how enterprises need to ensure that their needs are properly being met.
Aug. 1, 2015 08:00 AM EDT Reads: 1,684
SYS-CON Events announced today that MobiDev, a software development company, will exhibit at the 17th International Cloud Expo®, which will take place November 3–5, 2015, at the Santa Clara Convention Center in Santa Clara, CA. MobiDev is a software development company with representative offices in Atlanta (US), Sheffield (UK) and Würzburg (Germany); and development centers in Ukraine. Since 2009 it has grown from a small group of passionate engineers and business managers to a full-scale mobi...
Aug. 1, 2015 08:00 AM EDT Reads: 300
Learn how to solve the problem of keeping files in sync between multiple Docker containers. In his session at 16th Cloud Expo, Aaron Brongersma, Senior Infrastructure Engineer at Modulus, discussed using rsync, GlusterFS, EBS and Bit Torrent Sync. He broke down the tools that are needed to help create a seamless user experience. In the end, can we have an environment where we can easily move Docker containers, servers, and volumes without impacting our applications? He shared his results so yo...
Jul. 31, 2015 11:45 PM EDT Reads: 785
Palerra, the cloud security automation company, announced enhanced support for Amazon AWS, allowing IT security and DevOps teams to automate activity and configuration monitoring, anomaly detection, and orchestrated remediation, thereby meeting compliance mandates within complex infrastructure deployments. "Monitoring and threat detection for AWS is a non-trivial task. While Amazon's flexible environment facilitates successful DevOps implementations, it adds another layer, which can become a ...
Jul. 31, 2015 10:15 PM EDT Reads: 314
With SaaS use rampant across organizations, how can IT departments track company data and maintain security? More and more departments are commissioning their own solutions and bypassing IT. A cloud environment is amorphous and powerful, allowing you to set up solutions for all of your user needs: document sharing and collaboration, mobile access, e-mail, even industry-specific applications. In his session at 16th Cloud Expo, Shawn Mills, President and a founder of Green House Data, discussed h...
Jul. 31, 2015 04:30 PM EDT Reads: 430
The Software Defined Data Center (SDDC), which enables organizations to seamlessly run in a hybrid cloud model (public + private cloud), is here to stay. IDC estimates that the software-defined networking market will be valued at $3.7 billion by 2016. Security is a key component and benefit of the SDDC, and offers an opportunity to build security 'from the ground up' and weave it into the environment from day one. In his session at 16th Cloud Expo, Reuven Harrison, CTO and Co-Founder of Tufin,...
Jul. 31, 2015 03:00 PM EDT Reads: 498
In their session at 17th Cloud Expo, Hal Schwartz, CEO of Secure Infrastructure & Services (SIAS), and Chuck Paolillo, CTO of Secure Infrastructure & Services (SIAS), provide a study of cloud adoption trends and the power and flexibility of IBM Power and Pureflex cloud solutions. In his role as CEO of Secure Infrastructure & Services (SIAS), Hal Schwartz provides leadership and direction for the company.
Jul. 31, 2015 11:45 AM EDT Reads: 139
In a recent research, analyst firm IDC found that the average cost of a critical application failure is $500,000 to $1 million per hour and the average total cost of unplanned application downtime is $1.25 billion to $2.5 billion per year for Fortune 1000 companies. In addition to the findings on the cost of the downtime, the research also highlighted best practices for development, testing, application support, infrastructure, and operations teams.
Jul. 31, 2015 11:45 AM EDT Reads: 125
For IoT to grow as quickly as analyst firms’ project, a lot is going to fall on developers to quickly bring applications to market. But the lack of a standard development platform threatens to slow growth and make application development more time consuming and costly, much like we’ve seen in the mobile space. In his session at @ThingsExpo, Mike Weiner, Product Manager of the Omega DevCloud with KORE Telematics Inc., discussed the evolving requirements for developers as IoT matures and conducte...
Jul. 31, 2015 08:45 AM EDT Reads: 305