Welcome!

News Feed Item

CASIS Payloads Berthed With the International Space Station Through SpaceX Dragon Capsule

KENNEDY SPACE CENTER, Fla., April 21, 2014 /PRNewswire-USNewswire/ -- The Center for the Advancement of Science in Space (CASIS) is proud to announce its research payloads berthed with the International Space Station (ISS) on Sunday, April 20. Space Exploration Technologies Corporation's (SpaceX) Dragon capsule successfully berthed with the ISS, marking the completion of its launch to resupply the ISS with cargo and research. CASIS is tasked with managing and promoting research onboard the ISS U.S. National Laboratory.  

Research onboard the SpaceX Dragon capsule included a range of experiments from life sciences. This is the second mission that has been responsible for launching CASIS-sponsored investigations to the ISS. In January, Orbital Sciences Corporation's Cygnus capsule sent the first CASIS-sponsored investigations to the ISS. Below is an overview of the major payloads now onboard the ISS sponsored by CASIS:

Crystalline Monoclonal Antibody
Paul Reichert, Merck Research Laboratories
Commercial investigator Merck will focus on the protein crystal growth of a human monoclonal antibody developed by its research labs that is currently undergoing clinical trials for treatment of an immunological disease. High quality crystalline suspensions of the antibodies in microgravity will aid in not only structure determination but also pharmaceutical applications, such as drug delivery and purification/storage of the therapeutic substance.

IPPase Crystal Growth in Microgravity
Dr. Joseph Ng, iXpressGenes, Inc.
This investigation will produce protein crystals large enough for a specific type of crystallography that can show very intricate details of protein structure. The specific enzyme being studied is involved in a variety of cell functions, including protein production — but a very detailed part of how this enzyme works is unknown. Producing crystals that allow analysis of very small and detailed structural features will not only help researchers understand this protein's function but also determine best practices for studies of other proteins at this level of detail. 

Crystallization of Medically Relevant Proteins Using Microgravity
Dr. Sergey Korolev, St. Louis Medical Center
Research on this investigation focuses on improving crystals of two medically important proteins. These two proteins have multiple functions within cells, and results could therefore assist in the development of various medical interventions, from anticoagulant therapies to drug treatments for cardiovascular disease, diabetes, muscular dystrophy and Parkinson's disease.

Exploiting On-Orbit Crystal Properties for Structural Studies of Medically and Economically Important Targets
Dr. Edward Snell, SUNY Buffalo
This research focuses on growing crystals of four proteins associated with human disease. These proteins crystallize on Earth but not with sufficient quality and uniformity to determine their structures. Larger, better-organized crystals of these specific proteins could have a significant impact on drug development for Parkinson's disease, bovine spongiform encephalopathy, ethylmalonic aciduri and cutaneous squamous cell carcinoma.

Crystallization of Huntingtin Exon 1 Using Microgravity
Dr. Pamela Bjorkman, California Institute of Technology
This research focuses huntingtin, the protein responsible for Huntington's disease. The structure of this protein remains unknown. Procuring a high-resolution structure would have significant scientific and medical impact in understanding the structural basis for neural toxicity and developing treatments for Huntington's disease and other related disorders, such as spinocerebellar ataxia.

Crystallization of Human Membrane ABC Proteins in Microgravity
Dr. Stephen Aller, University of Alabama-Birmingham
This investigation focuses on determining the structure of human membrane proteins, which could accelerate the commercialization of next-generation drugs to treat AIDS-related dementia, high cholesterol, atherosclerosis, cystic fibrosis and multi-drug resistance as it relates to cancer.

Molecular Biology of Plant Development in the Spaceflight Environment
Dr. Anna-Lisa Paul, University of Florida
This research focuses on the growth and development of Arabidopsis thaliana seedlings in the spaceflight environment. Researchers seek to identify the genes involved in plant root morphology and adaptive physiology; specifically, how a root knows in which direction to grow when gravity is absent. Results will expand on previous ISS research in this area and inform the study of specific molecular pathways involved in plant adaptive physiology on Earth.

Many of the experiments delivered by the SpaceX Dragon capsule come from the first CASIS-sponsored RFP, "Advancing Protein Crystallization in Microgravity." CASIS believes that through this research, potential therapies can be developed and a baseline for future protein crystal growth experimentation will be established. Additionally, a joint project from NASA, CASIS and the National Institute of Health is onboard, "T-Cell Activation in Aging," in which Dr. Millie Hughes-Fulford will attempt to better understand and develop treatments for disorders of immune suppression by discovering the molecular basis of T-cell suppression in spaceflight.

"Today signifies yet another historic moment for CASIS and our launch partner, SpaceX," said President and Executive Director Gregory H. Johnson. "The research that is now on the ISS has the potential to unlock secrets that could create therapies to improve human health and performance. Additionally, this launch culminates our first official increment period of Advancing Research Knowledge 1. This initial launch period has been instrumental in the further development of CASIS and we look forward to sending additional exciting and innovative research capable of enhancing science in space, for life on Earth."

To learn more about the research destined for the ISS during the first official launch increment period for CASIS, Advancing Research Knowledge 1 (ARK1), please visit: ark1.iss-casis.org

About CASIS: The Center for the Advancement of Science in Space (CASIS) was selected by NASA in July 2011 to maximize use of the International Space Station (ISS) U.S. National Laboratory through 2020. CASIS is dedicated to supporting and accelerating innovations and new discoveries that will enhance the health and wellbeing of people and our planet. For more information, visit www.iss-casis.org.

About the ISS National Laboratory: In 2005, Congress designated the U.S. portion of the International Space Station as the nation's newest national laboratory to maximize its use for improving life on Earth, promoting collaboration among diverse users, and advancing STEM education. This unique laboratory environment is available for use by other U.S. government agencies and by academic and private institutions, providing access to the permanent microgravity setting, vantage point in low Earth orbit, and varied environments of space.

Media Contact: Patrick O'Neill
(321) 480-1054
[email protected]

SOURCE Center for the Advancement of Science in Space

More Stories By PR Newswire

Copyright © 2007 PR Newswire. All rights reserved. Republication or redistribution of PRNewswire content is expressly prohibited without the prior written consent of PRNewswire. PRNewswire shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.

Latest Stories
SYS-CON Events announced today that IBM has been named “Diamond Sponsor” of SYS-CON's 21st Cloud Expo, which will take place on October 31 through November 2nd 2017 at the Santa Clara Convention Center in Santa Clara, California.
A look across the tech landscape at the disruptive technologies that are increasing in prominence and speculate as to which will be most impactful for communications – namely, AI and Cloud Computing. In his session at 20th Cloud Expo, Curtis Peterson, VP of Operations at RingCentral, highlighted the current challenges of these transformative technologies and shared strategies for preparing your organization for these changes. This “view from the top” outlined the latest trends and developments i...
When growing capacity and power in the data center, the architectural trade-offs between server scale-up vs. scale-out continue to be debated. Both approaches are valid: scale-out adds multiple, smaller servers running in a distributed computing model, while scale-up adds fewer, more powerful servers that are capable of running larger workloads. It’s worth noting that there are additional, unique advantages that scale-up architectures offer. One big advantage is large memory and compute capacity...
"Loom is applying artificial intelligence and machine learning into the entire log analysis process, from start to finish and at the end you will get a human touch,” explained Sabo Taylor Diab, Vice President, Marketing at Loom Systems, in this SYS-CON.tv interview at 20th Cloud Expo, held June 6-8, 2017, at the Javits Center in New York City, NY.
In 2014, Amazon announced a new form of compute called Lambda. We didn't know it at the time, but this represented a fundamental shift in what we expect from cloud computing. Now, all of the major cloud computing vendors want to take part in this disruptive technology. In his session at 20th Cloud Expo, Doug Vanderweide, an instructor at Linux Academy, discussed why major players like AWS, Microsoft Azure, IBM Bluemix, and Google Cloud Platform are all trying to sidestep VMs and containers wit...
"We are a monitoring company. We work with Salesforce, BBC, and quite a few other big logos. We basically provide monitoring for them, structure for their cloud services and we fit into the DevOps world" explained David Gildeh, Co-founder and CEO of Outlyer, in this SYS-CON.tv interview at DevOps Summit at 20th Cloud Expo, held June 6-8, 2017, at the Javits Center in New York City, NY.
In his session at @ThingsExpo, Eric Lachapelle, CEO of the Professional Evaluation and Certification Board (PECB), provided an overview of various initiatives to certify the security of connected devices and future trends in ensuring public trust of IoT. Eric Lachapelle is the Chief Executive Officer of the Professional Evaluation and Certification Board (PECB), an international certification body. His role is to help companies and individuals to achieve professional, accredited and worldwide re...
With major technology companies and startups seriously embracing Cloud strategies, now is the perfect time to attend 21st Cloud Expo October 31 - November 2, 2017, at the Santa Clara Convention Center, CA, and June 12-14, 2018, at the Javits Center in New York City, NY, and learn what is going on, contribute to the discussions, and ensure that your enterprise is on the right path to Digital Transformation.
Automation is enabling enterprises to design, deploy, and manage more complex, hybrid cloud environments. Yet the people who manage these environments must be trained in and understanding these environments better than ever before. A new era of analytics and cognitive computing is adding intelligence, but also more complexity, to these cloud environments. How smart is your cloud? How smart should it be? In this power panel at 20th Cloud Expo, moderated by Conference Chair Roger Strukhoff, pane...
@DevOpsSummit at Cloud Expo taking place Oct 31 - Nov 2, 2017, at the Santa Clara Convention Center, Santa Clara, CA, is co-located with the 21st International Cloud Expo and will feature technical sessions from a rock star conference faculty and the leading industry players in the world. The widespread success of cloud computing is driving the DevOps revolution in enterprise IT. Now as never before, development teams must communicate and collaborate in a dynamic, 24/7/365 environment. There is ...
New competitors, disruptive technologies, and growing expectations are pushing every business to both adopt and deliver new digital services. This ‘Digital Transformation’ demands rapid delivery and continuous iteration of new competitive services via multiple channels, which in turn demands new service delivery techniques – including DevOps. In this power panel at @DevOpsSummit 20th Cloud Expo, moderated by DevOps Conference Co-Chair Andi Mann, panelists examined how DevOps helps to meet the de...
No hype cycles or predictions of zillions of things here. IoT is big. You get it. You know your business and have great ideas for a business transformation strategy. What comes next? Time to make it happen. In his session at @ThingsExpo, Jay Mason, Associate Partner at M&S Consulting, presented a step-by-step plan to develop your technology implementation strategy. He discussed the evaluation of communication standards and IoT messaging protocols, data analytics considerations, edge-to-cloud tec...
What's the role of an IT self-service portal when you get to continuous delivery and Infrastructure as Code? This general session showed how to create the continuous delivery culture and eight accelerators for leading the change. Don Demcsak is a DevOps and Cloud Native Modernization Principal for Dell EMC based out of New Jersey. He is a former, long time, Microsoft Most Valuable Professional, specializing in building and architecting Application Delivery Pipelines for hybrid legacy, and cloud ...
Amazon started as an online bookseller 20 years ago. Since then, it has evolved into a technology juggernaut that has disrupted multiple markets and industries and touches many aspects of our lives. It is a relentless technology and business model innovator driving disruption throughout numerous ecosystems. Amazon’s AWS revenues alone are approaching $16B a year making it one of the largest IT companies in the world. With dominant offerings in Cloud, IoT, eCommerce, Big Data, AI, Digital Assista...
Artificial intelligence, machine learning, neural networks. We’re in the midst of a wave of excitement around AI such as hasn’t been seen for a few decades. But those previous periods of inflated expectations led to troughs of disappointment. Will this time be different? Most likely. Applications of AI such as predictive analytics are already decreasing costs and improving reliability of industrial machinery. Furthermore, the funding and research going into AI now comes from a wide range of com...