|By Business Wire||
|April 29, 2014 12:03 PM EDT||
Bina Technologies today announced the early release of the Bina Annotation Platform, the newest addition to Bina’s highly scalable and accurate genomic analysis product suite. With this addition, Bina allows users to perform secondary analysis (alignment, variant calling) as well as annotation and filtering on their NGS datasets in an integrated, easy-to-use platform with unprecedented speed and scalability.
The Bina Annotation Platform is the fastest, most scalable annotation solution available on the market, empowering scientists to access more than 130 annotation features and search, filter, and annotate their variant files in a fraction of a second. Users can define and save custom and multi-level filters using any combination of important associations and functional databases available on the platform.
Typical NGS whole genome studies yield between 4-5 million variants. Because of the complexity and sheer amount of data, assigning biological meaning and extracting the relevant variants remains one of the primary challenges that biologists and clinical researchers face. Whereas many current annotation tools can’t process an entire whole human genome, the Bina Annotation Module can easily and quickly annotate complex whole genome data sets.
“The Bina Annotation platform provides a great way to comprehensively annotate sequence variants,” said Dr. Ekta Khurana, Yale University. “The user-interface is very intuitive and the process is very fast, allowing more downstream analyses in a fraction of the time required with other approaches.” Dr. Khurana, a research scientist in the Program in Computational Biology and Bioinformatics, is the primary author of a recent publication in Science on annotating human gene variants for cancer genomics applications.
Users can upload their NGS data analysis results or push them directly from Bina’s secondary analysis appliances to the cloud-based Bina Annotation Platform. The Platform then quickly provides current information about relevant variants using databases that are in active use by the scientific community, including HGMD, PGMD, ClinVar, COSMIC, dbNSFP, TRANSFAC, 1000 Genomes, and more. Once the annotation is complete, researchers can interact with their data in real-time, through filtering of all identified variants according to user selected annotation and data quality criteria. All this takes place in an intuitive and easy-to-use interface designed specifically for the clinical researcher.
“Bina’s Annotation Platform provides comprehensive annotation to NGS data with the most relevant scientific and clinical content. Its sub-second query response for WGS and WES (whole genome and whole exome) is unprecedented, definitely facilitating genome interpretation,” added Dr. Shashikant Kulkarni, Associate Professor, Pathology and Immunology and the Head of Clinical Genomics, Genomics and Pathology Services at Washington University School of Medicine
“Prior to Bina’s Annotation Platform, researchers had to wait days, if not weeks, to perform partial analysis on a whole human genome,” said Narges Bani Asadi, CEO of Bina Technologies. “Today, clinical researchers have the ability to bring meaning to their entire NGS data sets in under 60 minutes. Faster, smarter annotation takes us one step closer to our goal of bringing personalized medicine tools to academic and clinical researchers everywhere.”
The Bina Technologies team will be presenting the Bina Annotation Platform to the public this week at the Bio-IT World Expo from April 29th - May 1 in Boston, MA. They will be exhibiting at booth #260, and will present on April 29th at the Vendor Showcase.
To learn more about Bina’s Annotation Platform, please visit: http://binatechnologies.com.
About Bina Technologies
Bina Technologies is defining the standards of high performance genomic analysis. Bina’s integrated, scalable, and comprehensive analysis platform empowers clinical and academic researchers to gain insight from their genomics data sets. Bina’s products dramatically decrease the complexity, time, and cost of the analysis, accelerating the science of personalized medicine.
Bina is an interdisciplinary team of engineers, computer scientists, and genomics scientists, revolutionizing human health and genomics research.
To learn more, visit: http://binatechnologies.com.
SYS-CON Events announced today the Kubernetes and Google Container Engine Workshop, being held November 3, 2016, in conjunction with @DevOpsSummit at 19th Cloud Expo at the Santa Clara Convention Center in Santa Clara, CA. This workshop led by Sebastian Scheele introduces participants to Kubernetes and Google Container Engine (GKE). Through a combination of instructor-led presentations, demonstrations, and hands-on labs, students learn the key concepts and practices for deploying and maintainin...
Jul. 25, 2016 08:00 AM EDT Reads: 679
Ovum, a leading technology analyst firm, has published an in-depth report, Ovum Decision Matrix: Selecting a DevOps Release Management Solution, 2016–17. The report focuses on the automation aspects of DevOps, Release Management and compares solutions from the leading vendors.
Jul. 25, 2016 08:00 AM EDT Reads: 1,643
"Avere Systems is a hybrid cloud solution provider. We have customers that want to use cloud storage and we have customers that want to take advantage of cloud compute," explained Rebecca Thompson, VP of Marketing at Avere Systems, in this SYS-CON.tv interview at 18th Cloud Expo, held June 7-9, 2016, at the Javits Center in New York City, NY.
Jul. 25, 2016 07:30 AM EDT Reads: 1,994
"We formed Formation several years ago to really address the need for bring complete modernization and software-defined storage to the more classic private cloud marketplace," stated Mark Lewis, Chairman and CEO of Formation Data Systems, in this SYS-CON.tv interview at 18th Cloud Expo, held June 7-9, 2016, at the Javits Center in New York City, NY.
Jul. 25, 2016 06:30 AM EDT Reads: 1,483
When it comes to cloud computing, the ability to turn massive amounts of compute cores on and off on demand sounds attractive to IT staff, who need to manage peaks and valleys in user activity. With cloud bursting, the majority of the data can stay on premises while tapping into compute from public cloud providers, reducing risk and minimizing need to move large files. In his session at 18th Cloud Expo, Scott Jeschonek, Director of Product Management at Avere Systems, discussed the IT and busin...
Jul. 25, 2016 06:00 AM EDT Reads: 1,750
Large scale deployments present unique planning challenges, system commissioning hurdles between IT and OT and demand careful system hand-off orchestration. In his session at @ThingsExpo, Jeff Smith, Senior Director and a founding member of Incenergy, will discuss some of the key tactics to ensure delivery success based on his experience of the last two years deploying Industrial IoT systems across four continents.
Jul. 25, 2016 06:00 AM EDT Reads: 1,458
There will be new vendors providing applications, middleware, and connected devices to support the thriving IoT ecosystem. This essentially means that electronic device manufacturers will also be in the software business. Many will be new to building embedded software or robust software. This creates an increased importance on software quality, particularly within the Industrial Internet of Things where business-critical applications are becoming dependent on products controlled by software. Qua...
Jul. 25, 2016 05:45 AM EDT Reads: 1,351
SYS-CON Events has announced today that Roger Strukhoff has been named conference chair of Cloud Expo and @ThingsExpo 2016 Silicon Valley. The 19th Cloud Expo and 6th @ThingsExpo will take place on November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. "The Internet of Things brings trillions of dollars of opportunity to developers and enterprise IT, no matter how you measure it," stated Roger Strukhoff. "More importantly, it leverages the power of devices and the Interne...
Jul. 25, 2016 05:00 AM EDT Reads: 2,009
Machine Learning helps make complex systems more efficient. By applying advanced Machine Learning techniques such as Cognitive Fingerprinting, wind project operators can utilize these tools to learn from collected data, detect regular patterns, and optimize their own operations. In his session at 18th Cloud Expo, Stuart Gillen, Director of Business Development at SparkCognition, discussed how research has demonstrated the value of Machine Learning in delivering next generation analytics to imp...
Jul. 25, 2016 04:15 AM EDT Reads: 2,397
Most organizations prioritize data security only after their data has already been compromised. Proactive prevention is important, but how can you accomplish that on a small budget? Learn how the cloud, combined with a defense and in-depth approach, creates efficiencies by transferring and assigning risk. Security requires a multi-defense approach, and an in-house team may only be able to cherry pick from the essential components. In his session at 19th Cloud Expo, Vlad Friedman, CEO/Founder o...
Jul. 25, 2016 04:15 AM EDT Reads: 1,825
"We host and fully manage cloud data services, whether we store, the data, move the data, or run analytics on the data," stated Kamal Shannak, Senior Development Manager, Cloud Data Services, IBM, in this SYS-CON.tv interview at 18th Cloud Expo, held June 7-9, 2016, at the Javits Center in New York City, NY.
Jul. 25, 2016 04:00 AM EDT Reads: 1,184
As organizations shift towards IT-as-a-service models, the need for managing and protecting data residing across physical, virtual, and now cloud environments grows with it. Commvault can ensure protection, access and E-Discovery of your data – whether in a private cloud, a Service Provider delivered public cloud, or a hybrid cloud environment – across the heterogeneous enterprise. In his general session at 18th Cloud Expo, Randy De Meno, Chief Technologist - Windows Products and Microsoft Part...
Jul. 25, 2016 04:00 AM EDT Reads: 1,839
In addition to all the benefits, IoT is also bringing new kind of customer experience challenges - cars that unlock themselves, thermostats turning houses into saunas and baby video monitors broadcasting over the internet. This list can only increase because while IoT services should be intuitive and simple to use, the delivery ecosystem is a myriad of potential problems as IoT explodes complexity. So finding a performance issue is like finding the proverbial needle in the haystack.
Jul. 25, 2016 03:45 AM EDT Reads: 2,167
With over 720 million Internet users and 40–50% CAGR, the Chinese Cloud Computing market has been booming. When talking about cloud computing, what are the Chinese users of cloud thinking about? What is the most powerful force that can push them to make the buying decision? How to tap into them? In his session at 18th Cloud Expo, Yu Hao, CEO and co-founder of SpeedyCloud, answered these questions and discussed the results of SpeedyCloud’s survey.
Jul. 25, 2016 03:15 AM EDT Reads: 822
With the proliferation of both SQL and NoSQL databases, organizations can now target specific fit-for-purpose database tools for their different application needs regarding scalability, ease of use, ACID support, etc. Platform as a Service offerings make this even easier now, enabling developers to roll out their own database infrastructure in minutes with minimal management overhead. However, this same amount of flexibility also comes with the challenges of picking the right tool, on the right ...
Jul. 25, 2016 03:15 AM EDT Reads: 999