|By Business Wire||
|April 29, 2014 12:03 PM EDT||
Bina Technologies today announced the early release of the Bina Annotation Platform, the newest addition to Bina’s highly scalable and accurate genomic analysis product suite. With this addition, Bina allows users to perform secondary analysis (alignment, variant calling) as well as annotation and filtering on their NGS datasets in an integrated, easy-to-use platform with unprecedented speed and scalability.
The Bina Annotation Platform is the fastest, most scalable annotation solution available on the market, empowering scientists to access more than 130 annotation features and search, filter, and annotate their variant files in a fraction of a second. Users can define and save custom and multi-level filters using any combination of important associations and functional databases available on the platform.
Typical NGS whole genome studies yield between 4-5 million variants. Because of the complexity and sheer amount of data, assigning biological meaning and extracting the relevant variants remains one of the primary challenges that biologists and clinical researchers face. Whereas many current annotation tools can’t process an entire whole human genome, the Bina Annotation Module can easily and quickly annotate complex whole genome data sets.
“The Bina Annotation platform provides a great way to comprehensively annotate sequence variants,” said Dr. Ekta Khurana, Yale University. “The user-interface is very intuitive and the process is very fast, allowing more downstream analyses in a fraction of the time required with other approaches.” Dr. Khurana, a research scientist in the Program in Computational Biology and Bioinformatics, is the primary author of a recent publication in Science on annotating human gene variants for cancer genomics applications.
Users can upload their NGS data analysis results or push them directly from Bina’s secondary analysis appliances to the cloud-based Bina Annotation Platform. The Platform then quickly provides current information about relevant variants using databases that are in active use by the scientific community, including HGMD, PGMD, ClinVar, COSMIC, dbNSFP, TRANSFAC, 1000 Genomes, and more. Once the annotation is complete, researchers can interact with their data in real-time, through filtering of all identified variants according to user selected annotation and data quality criteria. All this takes place in an intuitive and easy-to-use interface designed specifically for the clinical researcher.
“Bina’s Annotation Platform provides comprehensive annotation to NGS data with the most relevant scientific and clinical content. Its sub-second query response for WGS and WES (whole genome and whole exome) is unprecedented, definitely facilitating genome interpretation,” added Dr. Shashikant Kulkarni, Associate Professor, Pathology and Immunology and the Head of Clinical Genomics, Genomics and Pathology Services at Washington University School of Medicine
“Prior to Bina’s Annotation Platform, researchers had to wait days, if not weeks, to perform partial analysis on a whole human genome,” said Narges Bani Asadi, CEO of Bina Technologies. “Today, clinical researchers have the ability to bring meaning to their entire NGS data sets in under 60 minutes. Faster, smarter annotation takes us one step closer to our goal of bringing personalized medicine tools to academic and clinical researchers everywhere.”
The Bina Technologies team will be presenting the Bina Annotation Platform to the public this week at the Bio-IT World Expo from April 29th - May 1 in Boston, MA. They will be exhibiting at booth #260, and will present on April 29th at the Vendor Showcase.
To learn more about Bina’s Annotation Platform, please visit: http://binatechnologies.com.
About Bina Technologies
Bina Technologies is defining the standards of high performance genomic analysis. Bina’s integrated, scalable, and comprehensive analysis platform empowers clinical and academic researchers to gain insight from their genomics data sets. Bina’s products dramatically decrease the complexity, time, and cost of the analysis, accelerating the science of personalized medicine.
Bina is an interdisciplinary team of engineers, computer scientists, and genomics scientists, revolutionizing human health and genomics research.
To learn more, visit: http://binatechnologies.com.
SYS-CON Events announced today that FalconStor Software® Inc., a 15-year innovator of software-defined storage solutions, will exhibit at SYS-CON's 18th International Cloud Expo®, which will take place on June 7-9, 2016, at the Javits Center in New York City, NY. FalconStor Software®, Inc. (NASDAQ: FALC) is a leading software-defined storage company offering a converged, hardware-agnostic, software-defined storage and data services platform. Its flagship solution FreeStor®, utilizes a horizonta...
Feb. 13, 2016 02:30 PM EST
With an estimated 50 billion devices connected to the Internet by 2020, several industries will begin to expand their capabilities for retaining end point data at the edge to better utilize the range of data types and sheer volume of M2M data generated by the Internet of Things. In his session at @ThingsExpo, Don DeLoach, CEO and President of Infobright, will discuss the infrastructures businesses will need to implement to handle this explosion of data by providing specific use cases for filte...
Feb. 13, 2016 02:00 PM EST Reads: 251
SYS-CON Events announced today that Pythian, a global IT services company specializing in helping companies adopt disruptive technologies to optimize revenue-generating systems, has been named “Bronze Sponsor” of SYS-CON's 18th Cloud Expo, which will take place on June 7-9, 2015 at the Javits Center in New York, New York. Founded in 1997, Pythian is a global IT services company that helps companies compete by adopting disruptive technologies such as cloud, Big Data, advanced analytics, and DevO...
Feb. 13, 2016 01:30 PM EST Reads: 277
SYS-CON Events announced today that Avere Systems, a leading provider of enterprise storage for the hybrid cloud, will exhibit at SYS-CON's 18th International Cloud Expo®, which will take place on June 7-9, 2016, at the Javits Center in New York City, NY. Avere delivers a more modern architectural approach to storage that doesn’t require the overprovisioning of storage capacity to achieve performance, overspending on expensive storage media for inactive data or the overbuilding of data centers ...
Feb. 13, 2016 01:30 PM EST Reads: 140
SYS-CON Events announced today that Commvault, a global leader in enterprise data protection and information management, has been named “Bronze Sponsor” of SYS-CON's 18th International Cloud Expo, which will take place on June 7–9, 2016, at the Javits Center in New York City, NY, and the 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. Commvault is a leading provider of data protection and information management...
Feb. 13, 2016 12:45 PM EST Reads: 469
The Quantified Economy represents the total global addressable market (TAM) for IoT that, according to a recent IDC report, will grow to an unprecedented $1.3 trillion by 2019. With this the third wave of the Internet-global proliferation of connected devices, appliances and sensors is poised to take off in 2016. In his session at @ThingsExpo, David McLauchlan, CEO and co-founder of Buddy Platform, will discuss how the ability to access and analyze the massive volume of streaming data from mil...
Feb. 13, 2016 12:00 PM EST
SYS-CON Events announced today that Alert Logic, Inc., the leading provider of Security-as-a-Service solutions for the cloud, will exhibit at SYS-CON's 18th International Cloud Expo®, which will take place on June 7-9, 2016, at the Javits Center in New York City, NY. Alert Logic, Inc., provides Security-as-a-Service for on-premises, cloud, and hybrid infrastructures, delivering deep security insight and continuous protection for customers at a lower cost than traditional security solutions. Ful...
Feb. 13, 2016 12:00 PM EST Reads: 470
SYS-CON Events announced today that Column Technologies will exhibit at SYS-CON's @DevOpsSummit at Cloud Expo, which will take place on June 7-9, 2016, at the Javits Center in New York City, NY. Established in 1998, Column Technologies is a global technology solutions provider with over 400 employees, headquartered in the United States with offices in Canada, India, and the United Kingdom. Column Technologies provides “Best of Breed” technology solutions that automate the key DevOps principal...
Feb. 13, 2016 12:00 PM EST
SYS-CON Events announced today that Interoute, owner-operator of one of Europe's largest networks and a global cloud services platform, has been named “Bronze Sponsor” of SYS-CON's 18th Cloud Expo, which will take place on June 7-9, 2015 at the Javits Center in New York, New York. Interoute is the owner-operator of one of Europe's largest networks and a global cloud services platform which encompasses 12 data centers, 14 virtual data centers and 31 colocation centers, with connections to 195 ad...
Feb. 13, 2016 12:00 PM EST Reads: 442
In most cases, it is convenient to have some human interaction with a web (micro-)service, no matter how small it is. A traditional approach would be to create an HTTP interface, where user requests will be dispatched and HTML/CSS pages must be served. This approach is indeed very traditional for a web site, but not really convenient for a web service, which is not intended to be good looking, 24x7 up and running and UX-optimized. Instead, talking to a web service in a chat-bot mode would be muc...
Feb. 13, 2016 11:45 AM EST Reads: 312
SYS-CON Events announced today that Men & Mice, the leading global provider of DNS, DHCP and IP address management overlay solutions, will exhibit at SYS-CON's 18th International Cloud Expo®, which will take place on June 7-9, 2016, at the Javits Center in New York City, NY. The Men & Mice Suite overlay solution is already known for its powerful application in heterogeneous operating environments, enabling enterprises to scale without fuss. Building on a solid range of diverse platform support,...
Feb. 13, 2016 11:45 AM EST Reads: 271
When building large, cloud-based applications that operate at a high scale, it’s important to maintain a high availability and resilience to failures. In order to do that, you must be tolerant of failures, even in light of failures in other areas of your application. “Fly two mistakes high” is an old adage in the radio control airplane hobby. It means, fly high enough so that if you make a mistake, you can continue flying with room to still make mistakes. In his session at 18th Cloud Expo, Lee...
Feb. 13, 2016 11:45 AM EST
More and more companies are looking to microservices as an architectural pattern for breaking apart applications into more manageable pieces so that agile teams can deliver new features quicker and more effectively. What this pattern has done more than anything to date is spark organizational transformations, setting the foundation for future application development. In practice, however, there are a number of considerations to make that go beyond simply “build, ship, and run,” which changes ho...
Feb. 13, 2016 11:30 AM EST Reads: 280
WebSocket is effectively a persistent and fat pipe that is compatible with a standard web infrastructure; a "TCP for the Web." If you think of WebSocket in this light, there are other more hugely interesting applications of WebSocket than just simply sending data to a browser. In his session at 18th Cloud Expo, Frank Greco, Director of Technology for Kaazing Corporation, will compare other modern web connectivity methods such as HTTP/2, HTTP Streaming, Server-Sent Events and new W3C event APIs ...
Feb. 13, 2016 11:30 AM EST
SYS-CON Events announced today that AppNeta, the leader in performance insight for business-critical web applications, will exhibit and present at SYS-CON's @DevOpsSummit at Cloud Expo New York, which will take place on June 7-9, 2016, at the Javits Center in New York City, NY. AppNeta is the only application performance monitoring (APM) company to provide solutions for all applications – applications you develop internally, business-critical SaaS applications you use and the networks that deli...
Feb. 13, 2016 11:30 AM EST Reads: 445