|By Business Wire||
|April 29, 2014 12:03 PM EDT||
Bina Technologies today announced the early release of the Bina Annotation Platform, the newest addition to Bina’s highly scalable and accurate genomic analysis product suite. With this addition, Bina allows users to perform secondary analysis (alignment, variant calling) as well as annotation and filtering on their NGS datasets in an integrated, easy-to-use platform with unprecedented speed and scalability.
The Bina Annotation Platform is the fastest, most scalable annotation solution available on the market, empowering scientists to access more than 130 annotation features and search, filter, and annotate their variant files in a fraction of a second. Users can define and save custom and multi-level filters using any combination of important associations and functional databases available on the platform.
Typical NGS whole genome studies yield between 4-5 million variants. Because of the complexity and sheer amount of data, assigning biological meaning and extracting the relevant variants remains one of the primary challenges that biologists and clinical researchers face. Whereas many current annotation tools can’t process an entire whole human genome, the Bina Annotation Module can easily and quickly annotate complex whole genome data sets.
“The Bina Annotation platform provides a great way to comprehensively annotate sequence variants,” said Dr. Ekta Khurana, Yale University. “The user-interface is very intuitive and the process is very fast, allowing more downstream analyses in a fraction of the time required with other approaches.” Dr. Khurana, a research scientist in the Program in Computational Biology and Bioinformatics, is the primary author of a recent publication in Science on annotating human gene variants for cancer genomics applications.
Users can upload their NGS data analysis results or push them directly from Bina’s secondary analysis appliances to the cloud-based Bina Annotation Platform. The Platform then quickly provides current information about relevant variants using databases that are in active use by the scientific community, including HGMD, PGMD, ClinVar, COSMIC, dbNSFP, TRANSFAC, 1000 Genomes, and more. Once the annotation is complete, researchers can interact with their data in real-time, through filtering of all identified variants according to user selected annotation and data quality criteria. All this takes place in an intuitive and easy-to-use interface designed specifically for the clinical researcher.
“Bina’s Annotation Platform provides comprehensive annotation to NGS data with the most relevant scientific and clinical content. Its sub-second query response for WGS and WES (whole genome and whole exome) is unprecedented, definitely facilitating genome interpretation,” added Dr. Shashikant Kulkarni, Associate Professor, Pathology and Immunology and the Head of Clinical Genomics, Genomics and Pathology Services at Washington University School of Medicine
“Prior to Bina’s Annotation Platform, researchers had to wait days, if not weeks, to perform partial analysis on a whole human genome,” said Narges Bani Asadi, CEO of Bina Technologies. “Today, clinical researchers have the ability to bring meaning to their entire NGS data sets in under 60 minutes. Faster, smarter annotation takes us one step closer to our goal of bringing personalized medicine tools to academic and clinical researchers everywhere.”
The Bina Technologies team will be presenting the Bina Annotation Platform to the public this week at the Bio-IT World Expo from April 29th - May 1 in Boston, MA. They will be exhibiting at booth #260, and will present on April 29th at the Vendor Showcase.
To learn more about Bina’s Annotation Platform, please visit: http://binatechnologies.com.
About Bina Technologies
Bina Technologies is defining the standards of high performance genomic analysis. Bina’s integrated, scalable, and comprehensive analysis platform empowers clinical and academic researchers to gain insight from their genomics data sets. Bina’s products dramatically decrease the complexity, time, and cost of the analysis, accelerating the science of personalized medicine.
Bina is an interdisciplinary team of engineers, computer scientists, and genomics scientists, revolutionizing human health and genomics research.
To learn more, visit: http://binatechnologies.com.
The essence of data analysis involves setting up data pipelines that consist of several operations that are chained together – starting from data collection, data quality checks, data integration, data analysis and data visualization (including the setting up of interaction paths in that visualization). In our opinion, the challenges stem from the technology diversity at each stage of the data pipeline as well as the lack of process around the analysis.
May. 25, 2016 08:30 PM EDT Reads: 1,195
The IoT is changing the way enterprises conduct business. In his session at @ThingsExpo, Eric Hoffman, Vice President at EastBanc Technologies, discuss how businesses can gain an edge over competitors by empowering consumers to take control through IoT. We'll cite examples such as a Washington, D.C.-based sports club that leveraged IoT and the cloud to develop a comprehensive booking system. He'll also highlight how IoT can revitalize and restore outdated business models, making them profitable...
May. 25, 2016 08:15 PM EDT Reads: 2,533
As machines are increasingly connected to the internet, it’s becoming easier to discover the numerous ways Industrial IoT (IIoT) is helping to shape the business world. This is exactly why we have decided to take a closer look at this pervasive movement and to examine the desire to connect more things! Now if you need a refresher on IIoT and how it is changing the world, take a moment and listen to Greg Gorbach with ARC Advisory Group. Gorbach believes, "IIoT will significantly change the worl...
May. 25, 2016 08:00 PM EDT Reads: 1,824
A strange thing is happening along the way to the Internet of Things, namely far too many devices to work with and manage. It has become clear that we'll need much higher efficiency user experiences that can allow us to more easily and scalably work with the thousands of devices that will soon be in each of our lives. Enter the conversational interface revolution, combining bots we can literally talk with, gesture to, and even direct with our thoughts, with embedded artificial intelligence, wh...
May. 25, 2016 08:00 PM EDT Reads: 1,871
Enterprise networks are complex. Moreover, they were designed and deployed to meet a specific set of business requirements at a specific point in time. But, the adoption of cloud services, new business applications and intensifying security policies, among other factors, require IT organizations to continuously deploy configuration changes. Therefore, enterprises are looking for better ways to automate the management of their networks while still leveraging existing capabilities, optimizing perf...
May. 25, 2016 07:00 PM EDT Reads: 1,050
The 19th International Cloud Expo has announced that its Call for Papers is open. Cloud Expo, to be held November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA, brings together Cloud Computing, Big Data, Internet of Things, DevOps, Containers, Microservices and WebRTC to one location. With cloud computing driving a higher percentage of enterprise IT budgets every year, it becomes increasingly important to plant your flag in this fast-expanding business opportunity. Submit y...
May. 25, 2016 06:00 PM EDT Reads: 1,885
SYS-CON Events announced today that MangoApps will exhibit at SYS-CON's 18th International Cloud Expo®, which will take place on June 7-9, 2016, at the Javits Center in New York City, NY. MangoApps provides modern company intranets and team collaboration software, allowing workers to stay connected and productive from anywhere in the world and from any device. For more information, please visit https://www.mangoapps.com/.
May. 25, 2016 05:45 PM EDT Reads: 458
Many banks and financial institutions are experimenting with containers in development environments, but when will they move into production? Containers are seen as the key to achieving the ultimate in information technology flexibility and agility. Containers work on both public and private clouds, and make it easy to build and deploy applications. The challenge for regulated industries is the cost and complexity of container security compliance. VM security compliance is already challenging, ...
May. 25, 2016 05:00 PM EDT Reads: 1,058
Internet of @ThingsExpo, taking place November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA, is co-located with the 19th International Cloud Expo and will feature technical sessions from a rock star conference faculty and the leading industry players in the world and ThingsExpo New York Call for Papers is now open.
May. 25, 2016 05:00 PM EDT Reads: 1,721
SYS-CON Events announced today that ContentMX, the marketing technology and services company with a singular mission to increase engagement and drive more conversations for enterprise, channel and SMB technology marketers, has been named “Sponsor & Exhibitor Lounge Sponsor” of SYS-CON's 18th Cloud Expo, which will take place on June 7-9, 2016, at the Javits Center in New York City, New York. “CloudExpo is a great opportunity to start a conversation with new prospects, but what happens after the...
May. 25, 2016 05:00 PM EDT Reads: 872
Designing IoT applications is complex, but deploying them in a scalable fashion is even more complex. A scalable, API first IaaS cloud is a good start, but in order to understand the various components specific to deploying IoT applications, one needs to understand the architecture of these applications and figure out how to scale these components independently. In his session at @ThingsExpo, Nara Rajagopalan is CEO of Accelerite, will discuss the fundamental architecture of IoT applications, ...
May. 25, 2016 04:45 PM EDT Reads: 946
In his session at 18th Cloud Expo, Bruce Swann, Senior Product Marketing Manager at Adobe, will discuss how the Adobe Marketing Cloud can help marketers embrace opportunities for personalized, relevant and real-time customer engagement across offline (direct mail, point of sale, call center) and digital (email, website, SMS, mobile apps, social networks, connected objects). Bruce Swann has more than 15 years of experience working with digital marketing disciplines like web analytics, social med...
May. 25, 2016 04:00 PM EDT Reads: 1,193
SYS-CON Events announced today that Enzu, a leading provider of cloud hosting solutions, will exhibit at SYS-CON's 18th International Cloud Expo®, which will take place on June 7-9, 2016, at the Javits Center in New York City, NY. Enzu’s mission is to be the leading provider of enterprise cloud solutions worldwide. Enzu enables online businesses to use its IT infrastructure to their competitive advantage. By offering a suite of proven hosting and management services, Enzu wants companies to foc...
May. 25, 2016 03:45 PM EDT Reads: 2,122
Customer experience has become a competitive differentiator for companies, and it’s imperative that brands seamlessly connect the customer journey across all platforms. With the continued explosion of IoT, join us for a look at how to build a winning digital foundation in the connected era – today and in the future. In his session at @ThingsExpo, Chris Nguyen, Group Product Marketing Manager at Adobe, will discuss how to successfully leverage mobile, rapidly deploy content, capture real-time d...
May. 25, 2016 02:45 PM EDT Reads: 1,439
IoT generates lots of temporal data. But how do you unlock its value? How do you coordinate the diverse moving parts that must come together when developing your IoT product? What are the key challenges addressed by Data as a Service? How does cloud computing underlie and connect the notions of Digital and DevOps What is the impact of the API economy? What is the business imperative for Cognitive Computing? Get all these questions and hundreds more like them answered at the 18th Cloud Expo...
May. 25, 2016 02:15 PM EDT Reads: 2,130