Welcome!

News Feed Item

Bina Technologies Introduces Annotation Platform to Bring Scientific Context to NGS Data Sets Quickly

Bina Technologies today announced the early release of the Bina Annotation Platform, the newest addition to Bina’s highly scalable and accurate genomic analysis product suite. With this addition, Bina allows users to perform secondary analysis (alignment, variant calling) as well as annotation and filtering on their NGS datasets in an integrated, easy-to-use platform with unprecedented speed and scalability.

The Bina Annotation Platform is the fastest, most scalable annotation solution available on the market, empowering scientists to access more than 130 annotation features and search, filter, and annotate their variant files in a fraction of a second. Users can define and save custom and multi-level filters using any combination of important associations and functional databases available on the platform.

Typical NGS whole genome studies yield between 4-5 million variants. Because of the complexity and sheer amount of data, assigning biological meaning and extracting the relevant variants remains one of the primary challenges that biologists and clinical researchers face. Whereas many current annotation tools can’t process an entire whole human genome, the Bina Annotation Module can easily and quickly annotate complex whole genome data sets.

“The Bina Annotation platform provides a great way to comprehensively annotate sequence variants,” said Dr. Ekta Khurana, Yale University. “The user-interface is very intuitive and the process is very fast, allowing more downstream analyses in a fraction of the time required with other approaches.” Dr. Khurana, a research scientist in the Program in Computational Biology and Bioinformatics, is the primary author of a recent publication in Science on annotating human gene variants for cancer genomics applications.

Users can upload their NGS data analysis results or push them directly from Bina’s secondary analysis appliances to the cloud-based Bina Annotation Platform. The Platform then quickly provides current information about relevant variants using databases that are in active use by the scientific community, including HGMD, PGMD, ClinVar, COSMIC, dbNSFP, TRANSFAC, 1000 Genomes, and more. Once the annotation is complete, researchers can interact with their data in real-time, through filtering of all identified variants according to user selected annotation and data quality criteria. All this takes place in an intuitive and easy-to-use interface designed specifically for the clinical researcher.

“Bina’s Annotation Platform provides comprehensive annotation to NGS data with the most relevant scientific and clinical content. Its sub-second query response for WGS and WES (whole genome and whole exome) is unprecedented, definitely facilitating genome interpretation,” added Dr. Shashikant Kulkarni, Associate Professor, Pathology and Immunology and the Head of Clinical Genomics, Genomics and Pathology Services at Washington University School of Medicine

“Prior to Bina’s Annotation Platform, researchers had to wait days, if not weeks, to perform partial analysis on a whole human genome,” said Narges Bani Asadi, CEO of Bina Technologies. “Today, clinical researchers have the ability to bring meaning to their entire NGS data sets in under 60 minutes. Faster, smarter annotation takes us one step closer to our goal of bringing personalized medicine tools to academic and clinical researchers everywhere.”

The Bina Technologies team will be presenting the Bina Annotation Platform to the public this week at the Bio-IT World Expo from April 29th - May 1 in Boston, MA. They will be exhibiting at booth #260, and will present on April 29th at the Vendor Showcase.

To learn more about Bina’s Annotation Platform, please visit: http://binatechnologies.com.

About Bina Technologies

Bina Technologies is defining the standards of high performance genomic analysis. Bina’s integrated, scalable, and comprehensive analysis platform empowers clinical and academic researchers to gain insight from their genomics data sets. Bina’s products dramatically decrease the complexity, time, and cost of the analysis, accelerating the science of personalized medicine.

Bina is an interdisciplinary team of engineers, computer scientists, and genomics scientists, revolutionizing human health and genomics research.

To learn more, visit: http://binatechnologies.com.

More Stories By Business Wire

Copyright © 2009 Business Wire. All rights reserved. Republication or redistribution of Business Wire content is expressly prohibited without the prior written consent of Business Wire. Business Wire shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.

Latest Stories
Between the mockups and specs produced by analysts, and resulting applications built by developers, there exists a gulf where projects fail, costs spiral, and applications disappoint. Methodologies like Agile attempt to address this with intensified communication, with partial success but many limitations. In his session at 18th Cloud Expo, Charles Kendrick, CTO & Chief Architect at Isomorphic Software, will present a revolutionary model enabled by new technologies. Learn how business and devel...
You think you know what’s in your data. But do you? Most organizations are now aware of the business intelligence represented by their data. Data science stands to take this to a level you never thought of – literally. The techniques of data science, when used with the capabilities of Big Data technologies, can make connections you had not yet imagined, helping you discover new insights and ask new questions of your data. In his session at @ThingsExpo, Sarbjit Sarkaria, data science team lead ...
The IoT has the potential to create a renaissance of manufacturing in the US and elsewhere. In his session at 18th Cloud Expo, Florent Solt, CTO and chief architect of Netvibes, will discuss how the expected exponential increase in the amount of data that will be processed, transported, stored, and accessed means there will be a huge demand for smart technologies to deliver it. Florent Solt is the CTO and chief architect of Netvibes. Prior to joining Netvibes in 2007, he co-founded Rift Technol...
If there is anything we have learned by now, is that every business paves their own unique path for releasing software- every pipeline, implementation and practices are a bit different, and DevOps comes in all shapes and sizes. Software delivery practices are often comprised of set of several complementing (or even competing) methodologies – such as leveraging Agile, DevOps and even a mix of ITIL, to create the combination that’s most suitable for your organization and that maximize your busines...
Struggling to keep up with increasing application demand? Learn how Platform as a Service (PaaS) can streamline application development processes and make resource management easy.
New Relic, Inc. has announced a set of new features across the New Relic Software Analytics Cloud that offer IT operations teams increased visibility, and the ability to diagnose and resolve performance problems quickly. The new features further IT operations teams’ ability to leverage data and analytics, as well as drive collaboration and a common, shared understanding between teams. Software teams are under pressure to resolve performance issues quickly and improve availability, as the comple...
The proper isolation of resources is essential for multi-tenant environments. The traditional approach to isolate resources is, however, rather heavyweight. In his session at 18th Cloud Expo, Igor Drobiazko, co-founder of elastic.io, will draw upon their own experience with operating a Docker container-based infrastructure on a large scale and present a lightweight solution for resource isolation using microservices. He will also discuss the implementation of microservices in data and applicat...
Join IBM June 8 at 18th Cloud Expo at the Javits Center in New York City, NY, and learn how to innovate like a startup and scale for the enterprise. You need to deliver quality applications faster and cheaper, attract and retain customers with an engaging experience across devices, and seamlessly integrate your enterprise systems. And you can't take 12 months to do it.
See storage differently! Storage performance problems have only gotten worse and harder to solve as applications have become largely virtualized and moved to a cloud-based infrastructure. Storage performance in a virtualized environment is not just about IOPS, it is about how well that potential performance is guaranteed to individual VMs for these apps as the number of VMs keep going up real time. In his session at 18th Cloud Expo, Dhiraj Sehgal, in product and marketing at Tintri, will discu...
Machine Learning helps make complex systems more efficient. By applying advanced Machine Learning techniques such as Cognitive Fingerprinting, wind project operators can utilize these tools to learn from collected data, detect regular patterns, and optimize their own operations. In his session at 18th Cloud Expo, Stuart Gillen, Director of Business Development at SparkCognition, will discuss how research has demonstrated the value of Machine Learning in delivering next generation analytics to im...
This is not a small hotel event. It is also not a big vendor party where politicians and entertainers are more important than real content. This is Cloud Expo, the world's longest-running conference and exhibition focused on Cloud Computing and all that it entails. If you want serious presentations and valuable insight about Cloud Computing for three straight days, then register now for Cloud Expo.
As you respond to increasing requests for new analytics, you need fast and flexible technology in your arsenal so that you can deploy the right workload to the right platform for the need at hand. Do you need self-service and fast time to value? Do you have data and application control and privacy needs, along with strict SLAs to meet? IBM dashDB™ is data warehouse technology powered by in-memory computing and in-database analytics that are designed for fast results, scalability and more.
SYS-CON Events announced today that SoftLayer, an IBM Company, has been named “Gold Sponsor” of SYS-CON's 18th Cloud Expo, which will take place on June 7-9, 2016, at the Javits Center in New York, New York. SoftLayer, an IBM Company, provides cloud infrastructure as a service from a growing number of data centers and network points of presence around the world. SoftLayer’s customers range from Web startups to global enterprises.
So, you bought into the current machine learning craze and went on to collect millions/billions of records from this promising new data source. Now, what do you do with them? Too often, the abundance of data quickly turns into an abundance of problems. How do you extract that "magic essence" from your data without falling into the common pitfalls? In her session at @ThingsExpo, Natalia Ponomareva, Software Engineer at Google, will provide tips on how to be successful in large scale machine lear...
Up until last year, enterprises that were looking into cloud services usually undertook a long-term pilot with one of the large cloud providers, running test and dev workloads in the cloud. With cloud’s transition to mainstream adoption in 2015, and with enterprises migrating more and more workloads into the cloud and in between public and private environments, the single-provider approach must be revisited. In his session at 18th Cloud Expo, Yoav Mor, multi-cloud solution evangelist at Cloudy...