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CORRECTING and REPLACING MolecularHealth Guides Better Cancer Treatments with Two New Diagnostic Tests
|By Business Wire
|May 7, 2014 10:04 AM EDT
Please replace the release with the following corrected version due to
The corrected release reads:
MOLECULARHEALTH GUIDES BETTER CANCER TREATMENTS WITH TWO NEW
TreatmentMAP platform combines precision medicine with advanced data
analytics to guide patients and physicians to the safest, most effective
cancer treatment options
Backed by more than eight years of research and development, MolecularHealth
announced today the official launch of TreatmentMAP™, its cancer
treatment decision support offering. Based on a proprietary analytics
engine, TreatmentMAP leverages the results of next generation sequencing
(NGS) genetic tests to identify the optimal, safest treatment options
for each individual patient. For the first time, cancer patients and
their medical teams will have access to actionable information to guide
the selection of targeted cancer treatments, presented in a clear and
understandable way. TreatmentMAP became commercially available in Europe
and the U.S. in April.
The company has two available versions of its offering:
Targeted Panel is the largest gene panel commercially
available today, with over 500 genes that cover several thousand
variants and have been determined to have the most clinical impact in
cancer, and are therefore most likely to make a difference in
Whole Exome, the first commercially available whole exome
analysis for cancer, taking a comprehensive look at a patient’s
genetic profile by examining the genes of both the tumor and germline.
Both testing options incorporate MolecularHealth’s SafetyMAP™, a
proprietary identification of drug target safety or resistance effects,
using the FDA’s Adverse Event Reporting Systems (AERS) as an input for
analysis. Through MolecularHealth’s five-year research collaboration
agreement with the FDA, MolecularHealth incorporates key data from AERS
into SafetyMAP, providing the first drug safety analysis that combines
adverse event information with molecular knowledge about drug activity
within a patient. This ensures that treatment options will not only be
effective, but won’t have unintended negative consequences for patients.
“I believe that the future of medicine lies in our ability to interpret
seemingly disparate information,” said Lloyd Everson, M.D., co-CEO of
MolecularHealth. “With the technology now at our disposal, there are
mountains of data constantly being churned out of labs and clinical
trials – but until recently, it was an unwieldy task to do anything
productive with that information. TreatmentMAP allows us to pull in all
of that data and make it truly usable.”
TreatmentMAP tests can be ordered in the United States and in Europe. In
the U.S., a patient’s oncologist or pathologist sends a tumor sample to
MolecularHealth’s CLIA-certified NGS lab in The Woodlands, Texas. Once
the sample is sequenced, data on the tumor’s DNA, along with additional
medical information on the patient, is fed into the company’s automated
analytics platform. This platform cross-references patient-specific data
with the latest peer-reviewed evidence, clinical trials, and other
sources. A simple-to-understand report is delivered to the patient’s
medical team, highlighting the treatment options that are most likely to
be both effective and safe.
“We are still trying to understand cancer, and as an oncologist I have
observed that the most effective cancer therapies are those that
precisely target the unique biology of an individual patient's tumor,”
said Joyce O’Shaughnessy, M.D., co-chair of breast cancer research at US
Oncology and Baylor-Sammons Cancer Center. “TreatmentMAP offers new
insights into the molecular drivers of a tumor, leading to expanded
therapeutic options and greater chance for therapy response.”
“As a pathologist, I’m happy to have a company joining the molecular
diagnostic space that’s more pathologist-friendly than some of the
competition in this field,” said Thomas Wheeler, M.D., chairman of the
Department of Pathology & Immunology at Baylor College of Medicine. “The
market can only benefit from having more options to meet the needs of
individual patients, and from what I’ve seen, MolecularHealth’s reports
are not only more robust, but focus on the elements that are most
important when determining a treatment path for a patient.”
Drs. O’Shaughnessy and Wheeler are members of the MolecularHealth
For more information on TreatmentMAP and how to order a test, please
MolecularHealth is a leading biomedical company transforming molecular
data into actionable clinical information for the most efficient and
safest cancer treatment options for each individual cancer patient. By
using advanced proprietary tumor analysis and interpretation to match
patient-specific genetic and molecular test findings to the current
state of the world’s biomedical knowledge about cancer, MolecularHealth
provides doctors and patients with faster, more accurate insights into
the role genes play in the progression and treatment of an individual’s
cancer. Eight years in development by a multidisciplinary team of
doctors, scientists and IT experts, MolecularHealth works in partnership
with some of the world’s leading healthcare and information technology
companies, including the U.S. Food and Drug Administration (FDA),
University of Texas MD Anderson Cancer Center, and SAP AG. The company
is headquartered in Heidelberg, Germany. U.S. headquarters, including a
CLIA-certified NGS lab, are located in The Woodlands, Texas. The company
also has offices in Boston, Mass.
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