|By Business Wire||
|May 27, 2014 01:54 PM EDT||
The march of modern medicine is often driven by revolutions in medical imaging. When technology advances, doctors are better able to peer deeply into human tissues, and thus able to detect, diagnose and treat human diseases more effectively.
Now, researchers have taken an established imaging technology called “optical coherence tomography,” or OCT, and integrated it with other instruments to bring about the next revolution in imaging by helping doctors provide safer, less painful and more effective care for women in labor and people with diabetic retinopathy and glaucoma. Their research will be presented at CLEO: 2014 being held June 8-13 in San Jose, California, USA.
OCT uses scattered “echoes” or reflections of light waves to produce high-resolution images of biological tissues, similar to ultrasound imaging but with one order of magnitude improvement in the resolution. Ophthalmologists have been using OCT to examine the retina for years. More recently, OCT has been applied to a number of other clinical specialties, including oncology for early cancer detection and staging in the gastrointestinal and urogenital tract as well as in cardiology, where it is used to study the formation of plaques in coronary arteries in situ.
Bioengineer Yu Chen of the University of Maryland and his colleagues have developed a way to integrate an OCT device with an 18-gauge epidural needle. Epidural administration, Chen notes, is traditionally done blindly, using anatomical landmarks. But the team’s newly miniaturized handheld device lets anesthesiologists see tissue from the perspective of the tip of the epidural needle, which could help doctors to deliver spinal anesthetic to patients with less pain and fewer complications.
“Due to lack of visual feedback, failure rates are often high, leading to multiple needle insertions,” he says. Side effects of these failures can include trauma to blood vessels and punctures in the dura, the outermost membrane surrounding the brain and spinal cord.
“An OCT forward-imaging probe can provide anesthesiologists with real-time visualization of the microarchitecture of tissues and important landmarks, and thus could significantly improve the accuracy and the safety of the needle-based procedure,” Chen says.
The researchers have been successful in testing needle-guidance experiments on pig swine samples and hope to conduct a pre-clinical study of the device within the next year.
Presentation AM2O.3, titled “Real-time Epidural Anesthesia Guidance Using Optical Coherence Tomography Needle Probe will take place Monday, June 9, at 11:15 a.m. in Salon V & VI of the San Jose Convention Marriott.
Better blood monitors
A team at the University of California, Davis, led by Biomedical Engineer Vivek Srinivasan has shown how OCT can simultaneously measure blood flow and blood oxygenation in vessels, without the need for contrast agents.
Like ultrasound, OCT can provide structural information, but it can also be used to determine flow rates and for angiography, visualizing the interior of blood vessels, says Shau Poh Chong, a postdoctoral researcher in the Srinivasan lab.
“Conventional pulse oximetry measures oxygen saturation using transmitted light,” Chong says. “Performing these measurements quantitatively with reflected light has traditionally been difficult due to the unknown distance traveled by the light through scattering tissue.”
OCT directly determines the distance that light travels. Until now, however, it was difficult to use OCT to measure oxygen saturation in blood, due to additional modeling errors introduced by light scattering. At visible wavelengths, scattering is much lower relative to blood absorption than at infrared wavelengths, where OCT is typically performed. The OCT system developed in the Srinivasan lab uses broadband visible light to measure the amounts of both oxygenated and deoxygenated hemoglobin, the oxygen-carrying protein of blood, thus revealing oxygen saturation levels. In addition, the team developed new methods to further reduce modeling errors caused by light scattering.
“The broad set of measurements provided by the system, including angiography, oximetry and red blood cell flow rates enables the direct assessment of tissue oxygen metabolism, which is essential for understanding the evolution of oxygen supply and demand in numerous disease models,” Chong says. “In the future, these techniques could be applied to study metabolic changes in diseases that affect the human retina, such as diabetic retinopathy and glaucoma.”
Presentation ATh1O.2, titled “Optical Coherence Imaging of Microvascular Oxygenation and Hemodynamics will take place Thursday, June 12, at 8:30 a.m. in Willow Glen I - III of the San Jose Convention Marriott.
PRESS REGISTRATION: A press room for credentialed press and analysts will be located in the San Jose Convention Center, Sunday through Thursday, June 8-12. Those interested in obtaining a press badge for CLEO: 2014 should contact Lyndsay Meyer at 202.416.1435 or [email protected].
With a distinguished history as the industry's leading event on laser science, the Conference on Lasers and Electro-Optics (CLEO) is the premier international forum for scientific and technical optics, uniting the fields of lasers and opto-electronics by bringing together all aspects of laser technology, from basic research to industry applications. CLEO: Expo showcases the latest products and applications from more than 300 participating companies from around the world, providing hands-on demonstrations of the latest market innovations and applications. The Expo also offers valuable on-floor programming, including Market Focus and the Technology Transfer program.
Sponsored by the American Physical Society's (APS) Laser Science Division, IEEE Photonics Society and The Optical Society (OSA), CLEO provides the full range of critical developments in the field, showcasing the most significant milestones from laboratory to marketplace. With an unparalleled breadth and depth of coverage, CLEO connects all of the critical vertical markets in lasers and electro-optics. For more information, visit www.cleoconference.org. CLEO: 2014 takes place June 8 - 13 at the San Jose Convention Center.
"ReadyTalk is an audio and web video conferencing provider. We've really come to embrace WebRTC as the platform for our future of technology," explained Dan Cunningham, CTO of ReadyTalk, in this SYS-CON.tv interview at WebRTC Summit at 19th Cloud Expo, held November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA.
Dec. 10, 2016 05:30 PM EST Reads: 959
Financial Technology has become a topic of intense interest throughout the cloud developer and enterprise IT communities. Accordingly, attendees at the upcoming 20th Cloud Expo at the Javits Center in New York, June 6-8, 2017, will find fresh new content in a new track called FinTech.
Dec. 10, 2016 05:15 PM EST Reads: 2,342
Bert Loomis was a visionary. This general session will highlight how Bert Loomis and people like him inspire us to build great things with small inventions. In their general session at 19th Cloud Expo, Harold Hannon, Architect at IBM Bluemix, and Michael O'Neill, Strategic Business Development at Nvidia, discussed the accelerating pace of AI development and how IBM Cloud and NVIDIA are partnering to bring AI capabilities to "every day," on-demand. They also reviewed two "free infrastructure" pr...
Dec. 10, 2016 05:15 PM EST Reads: 1,378
Without lifecycle traceability and visibility across the tool chain, stakeholders from Planning-to-Ops have limited insight and answers to who, what, when, why and how across the DevOps lifecycle. This impacts the ability to deliver high quality software at the needed velocity to drive positive business outcomes. In his general session at @DevOpsSummit at 19th Cloud Expo, Phil Hombledal, Solution Architect at CollabNet, discussed how customers are able to achieve a level of transparency that e...
Dec. 10, 2016 04:30 PM EST Reads: 1,334
WebRTC is the future of browser-to-browser communications, and continues to make inroads into the traditional, difficult, plug-in web communications world. The 6th WebRTC Summit continues our tradition of delivering the latest and greatest presentations within the world of WebRTC. Topics include voice calling, video chat, P2P file sharing, and use cases that have already leveraged the power and convenience of WebRTC.
Dec. 10, 2016 04:30 PM EST Reads: 1,805
As data explodes in quantity, importance and from new sources, the need for managing and protecting data residing across physical, virtual, and cloud environments grow with it. Managing data includes protecting it, indexing and classifying it for true, long-term management, compliance and E-Discovery. Commvault can ensure this with a single pane of glass solution – whether in a private cloud, a Service Provider delivered public cloud or a hybrid cloud environment – across the heterogeneous enter...
Dec. 10, 2016 04:30 PM EST Reads: 1,891
Rapid innovation, changing business landscapes, and new IT demands force businesses to make changes quickly. In the eyes of many, containers are at the brink of becoming a pervasive technology in enterprise IT to accelerate application delivery. In this presentation, attendees learned about the: The transformation of IT to a DevOps, microservices, and container-based architecture What are containers and how DevOps practices can operate in a container-based environment A demonstration of how ...
Dec. 10, 2016 03:45 PM EST Reads: 1,306
Cloud Expo, Inc. has announced today that Andi Mann returns to 'DevOps at Cloud Expo 2017' as Conference Chair The @DevOpsSummit at Cloud Expo will take place on June 6-8, 2017, at the Javits Center in New York City, NY. "DevOps is set to be one of the most profound disruptions to hit IT in decades," said Andi Mann. "It is a natural extension of cloud computing, and I have seen both firsthand and in independent research the fantastic results DevOps delivers. So I am excited to help the great t...
Dec. 10, 2016 03:45 PM EST Reads: 886
"At ROHA we develop an app called Catcha. It was developed after we spent a year meeting with, talking to, interacting with senior citizens watching them use their smartphones and talking to them about how they use their smartphones so we could get to know their smartphone behavior," explained Dave Woods, Chief Innovation Officer at ROHA, in this SYS-CON.tv interview at 19th Cloud Expo, held November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA.
Dec. 10, 2016 03:30 PM EST Reads: 900
If you haven’t heard yet, CollabNet just put out some very big news for managing and gaining value from DevOps. We introduced CollabNet DevOps Lifecycle Manager (DLM) — a platform designed exclusively for providing a single pane of glass, dashboard, and traceability views across your DevOps toolchain and processes from planning to operations and that can be traced back to planning and development.
Dec. 10, 2016 02:45 PM EST Reads: 898
"Venafi has a platform that allows you to manage, centralize and automate the complete life cycle of keys and certificates within the organization," explained Gina Osmond, Sr. Field Marketing Manager at Venafi, in this SYS-CON.tv interview at DevOps at 19th Cloud Expo, held November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA.
Dec. 10, 2016 02:45 PM EST Reads: 1,237
@DevOpsSummit taking place June 6-8, 2017 at Javits Center, New York City, is co-located with the 20th International Cloud Expo and will feature technical sessions from a rock star conference faculty and the leading industry players in the world. @DevOpsSummit at Cloud Expo New York Call for Papers is now open.
Dec. 10, 2016 02:30 PM EST Reads: 2,048
SYS-CON Events announced today that Fusion, a leading provider of cloud services, will exhibit at SYS-CON's 20th International Cloud Expo®, which will take place on June 6-8, 2017, at the Javits Center in New York City, NY. Fusion, a leading provider of integrated cloud solutions to small, medium and large businesses, is the industry’s single source for the cloud. Fusion’s advanced, proprietary cloud service platform enables the integration of leading edge solutions in the cloud, including cloud...
Dec. 10, 2016 01:45 PM EST Reads: 715
Video experiences should be unique and exciting! But that doesn’t mean you need to patch all the pieces yourself. Users demand rich and engaging experiences and new ways to connect with you. But creating robust video applications at scale can be complicated, time-consuming and expensive. In his session at @ThingsExpo, Zohar Babin, Vice President of Platform, Ecosystem and Community at Kaltura, discussed how VPaaS enables you to move fast, creating scalable video experiences that reach your aud...
Dec. 10, 2016 01:00 PM EST Reads: 403
Regulatory requirements exist to promote the controlled sharing of information, while protecting the privacy and/or security of the information. Regulations for each type of information have their own set of rules, policies, and guidelines. Cloud Service Providers (CSP) are faced with increasing demand for services at decreasing prices. Demonstrating and maintaining compliance with regulations is a nontrivial task and doing so against numerous sets of regulatory requirements can be daunting task...
Dec. 10, 2016 01:00 PM EST Reads: 1,246