Welcome!

News Feed Item

New Research at CLEO: 2014 Could Lead to Precision-Guided Epidurals and Better Blood Monitors

The march of modern medicine is often driven by revolutions in medical imaging. When technology advances, doctors are better able to peer deeply into human tissues, and thus able to detect, diagnose and treat human diseases more effectively.

Now, researchers have taken an established imaging technology called “optical coherence tomography,” or OCT, and integrated it with other instruments to bring about the next revolution in imaging by helping doctors provide safer, less painful and more effective care for women in labor and people with diabetic retinopathy and glaucoma. Their research will be presented at CLEO: 2014 being held June 8-13 in San Jose, California, USA.

OCT uses scattered “echoes” or reflections of light waves to produce high-resolution images of biological tissues, similar to ultrasound imaging but with one order of magnitude improvement in the resolution. Ophthalmologists have been using OCT to examine the retina for years. More recently, OCT has been applied to a number of other clinical specialties, including oncology for early cancer detection and staging in the gastrointestinal and urogenital tract as well as in cardiology, where it is used to study the formation of plaques in coronary arteries in situ.

Precision-guided epidurals

Bioengineer Yu Chen of the University of Maryland and his colleagues have developed a way to integrate an OCT device with an 18-gauge epidural needle. Epidural administration, Chen notes, is traditionally done blindly, using anatomical landmarks. But the team’s newly miniaturized handheld device lets anesthesiologists see tissue from the perspective of the tip of the epidural needle, which could help doctors to deliver spinal anesthetic to patients with less pain and fewer complications.

“Due to lack of visual feedback, failure rates are often high, leading to multiple needle insertions,” he says. Side effects of these failures can include trauma to blood vessels and punctures in the dura, the outermost membrane surrounding the brain and spinal cord.

“An OCT forward-imaging probe can provide anesthesiologists with real-time visualization of the microarchitecture of tissues and important landmarks, and thus could significantly improve the accuracy and the safety of the needle-based procedure,” Chen says.

The researchers have been successful in testing needle-guidance experiments on pig swine samples and hope to conduct a pre-clinical study of the device within the next year.

Presentation AM2O.3, titled “Real-time Epidural Anesthesia Guidance Using Optical Coherence Tomography Needle Probe will take place Monday, June 9, at 11:15 a.m. in Salon V & VI of the San Jose Convention Marriott.

Better blood monitors

A team at the University of California, Davis, led by Biomedical Engineer Vivek Srinivasan has shown how OCT can simultaneously measure blood flow and blood oxygenation in vessels, without the need for contrast agents.

Like ultrasound, OCT can provide structural information, but it can also be used to determine flow rates and for angiography, visualizing the interior of blood vessels, says Shau Poh Chong, a postdoctoral researcher in the Srinivasan lab.

“Conventional pulse oximetry measures oxygen saturation using transmitted light,” Chong says. “Performing these measurements quantitatively with reflected light has traditionally been difficult due to the unknown distance traveled by the light through scattering tissue.”

OCT directly determines the distance that light travels. Until now, however, it was difficult to use OCT to measure oxygen saturation in blood, due to additional modeling errors introduced by light scattering. At visible wavelengths, scattering is much lower relative to blood absorption than at infrared wavelengths, where OCT is typically performed. The OCT system developed in the Srinivasan lab uses broadband visible light to measure the amounts of both oxygenated and deoxygenated hemoglobin, the oxygen-carrying protein of blood, thus revealing oxygen saturation levels. In addition, the team developed new methods to further reduce modeling errors caused by light scattering.

“The broad set of measurements provided by the system, including angiography, oximetry and red blood cell flow rates enables the direct assessment of tissue oxygen metabolism, which is essential for understanding the evolution of oxygen supply and demand in numerous disease models,” Chong says. “In the future, these techniques could be applied to study metabolic changes in diseases that affect the human retina, such as diabetic retinopathy and glaucoma.”

Presentation ATh1O.2, titled “Optical Coherence Imaging of Microvascular Oxygenation and Hemodynamics will take place Thursday, June 12, at 8:30 a.m. in Willow Glen I - III of the San Jose Convention Marriott.

PRESS REGISTRATION: A press room for credentialed press and analysts will be located in the San Jose Convention Center, Sunday through Thursday, June 8-12. Those interested in obtaining a press badge for CLEO: 2014 should contact Lyndsay Meyer at 202.416.1435 or [email protected].

About CLEO

With a distinguished history as the industry's leading event on laser science, the Conference on Lasers and Electro-Optics (CLEO) is the premier international forum for scientific and technical optics, uniting the fields of lasers and opto-electronics by bringing together all aspects of laser technology, from basic research to industry applications. CLEO: Expo showcases the latest products and applications from more than 300 participating companies from around the world, providing hands-on demonstrations of the latest market innovations and applications. The Expo also offers valuable on-floor programming, including Market Focus and the Technology Transfer program.

Sponsored by the American Physical Society's (APS) Laser Science Division, IEEE Photonics Society and The Optical Society (OSA), CLEO provides the full range of critical developments in the field, showcasing the most significant milestones from laboratory to marketplace. With an unparalleled breadth and depth of coverage, CLEO connects all of the critical vertical markets in lasers and electro-optics. For more information, visit www.cleoconference.org. CLEO: 2014 takes place June 8 - 13 at the San Jose Convention Center.

More Stories By Business Wire

Copyright © 2009 Business Wire. All rights reserved. Republication or redistribution of Business Wire content is expressly prohibited without the prior written consent of Business Wire. Business Wire shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.

Latest Stories
Fact: storage performance problems have only gotten more complicated, as applications not only have become largely virtualized, but also have moved to cloud-based infrastructures. Storage performance in virtualized environments isn’t just about IOPS anymore. Instead, you need to guarantee performance for individual VMs, helping applications maintain performance as the number of VMs continues to go up in real time. In his session at Cloud Expo, Dhiraj Sehgal, Product and Marketing at Tintri, wil...
19th Cloud Expo, taking place November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA, will feature technical sessions from a rock star conference faculty and the leading industry players in the world. Cloud computing is now being embraced by a majority of enterprises of all sizes. Yesterday's debate about public vs. private has transformed into the reality of hybrid cloud: a recent survey shows that 74% of enterprises have a hybrid cloud strategy. Meanwhile, 94% of enterpri...
Enterprises have forever faced challenges surrounding the sharing of their intellectual property. Emerging cloud adoption has made it more compelling for enterprises to digitize their content, making them available over a wide variety of devices across the Internet. In his session at 19th Cloud Expo, Santosh Ahuja, Director of Architecture at Impiger Technologies, will introduce various mechanisms provided by cloud service providers today to manage and share digital content in a secure manner....
Smart Cities are here to stay, but for their promise to be delivered, the data they produce must not be put in new siloes. In his session at @ThingsExpo, Mathias Herberts, Co-founder and CTO of Cityzen Data, will deep dive into best practices that will ensure a successful smart city journey.
SYS-CON Events announced today that 910Telecom will exhibit at the 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. Housed in the classic Denver Gas & Electric Building, 910 15th St., 910Telecom is a carrier-neutral telecom hotel located in the heart of Denver. Adjacent to CenturyLink, AT&T, and Denver Main, 910Telecom offers connectivity to all major carriers, Internet service providers, Internet backbones and ...
To leverage Continuous Delivery, enterprises must consider impacts that span functional silos, as well as applications that touch older, slower moving components. Managing the many dependencies can cause slowdowns. See how to achieve continuous delivery in the enterprise.
There is growing need for data-driven applications and the need for digital platforms to build these apps. In his session at 19th Cloud Expo, Muddu Sudhakar, VP and GM of Security & IoT at Splunk, will cover different PaaS solutions and Big Data platforms that are available to build applications. In addition, AI and machine learning are creating new requirements that developers need in the building of next-gen apps. The next-generation digital platforms have some of the past platform needs a...
SYS-CON Events announced today Telecom Reseller has been named “Media Sponsor” of SYS-CON's 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. Telecom Reseller reports on Unified Communications, UCaaS, BPaaS for enterprise and SMBs. They report extensively on both customer premises based solutions such as IP-PBX as well as cloud based and hosted platforms.
DevOps at Cloud Expo – being held November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA – announces that its Call for Papers is open. Born out of proven success in agile development, cloud computing, and process automation, DevOps is a macro trend you cannot afford to miss. From showcase success stories from early adopters and web-scale businesses, DevOps is expanding to organizations of all sizes, including the world's largest enterprises – and delivering real results. Am...
I wanted to gather all of my Internet of Things (IOT) blogs into a single blog (that I could later use with my University of San Francisco (USF) Big Data “MBA” course). However as I started to pull these blogs together, I realized that my IOT discussion lacked a vision; it lacked an end point towards which an organization could drive their IOT envisioning, proof of value, app dev, data engineering and data science efforts. And I think that the IOT end point is really quite simple…
Internet of @ThingsExpo, taking place November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA, is co-located with 19th Cloud Expo and will feature technical sessions from a rock star conference faculty and the leading industry players in the world. The Internet of Things (IoT) is the most profound change in personal and enterprise IT since the creation of the Worldwide Web more than 20 years ago. All major researchers estimate there will be tens of billions devices - comp...
StarNet Communications Corp has announced the addition of three Secure Remote Desktop modules to its flagship X-Win32 PC X server. The new modules enable X-Win32 to safely tunnel the remote desktops from Linux and Unix servers to the user’s PC over encrypted SSH. Traditionally, users of PC X servers deploy the XDMCP protocol to display remote desktop environments such as the Gnome and KDE desktops on Linux servers and the CDE environment on Solaris Unix machines. XDMCP is used primarily on comp...
Traditional on-premises data centers have long been the domain of modern data platforms like Apache Hadoop, meaning companies who build their business on public cloud were challenged to run Big Data processing and analytics at scale. But recent advancements in Hadoop performance, security, and most importantly cloud-native integrations, are giving organizations the ability to truly gain value from all their data. In his session at 19th Cloud Expo, David Tishgart, Director of Product Marketing ...
SYS-CON Events announced today that eCube Systems, a leading provider of middleware modernization, integration, and management solutions, will exhibit at @DevOpsSummit at 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. eCube Systems offers a family of middleware evolution products and services that maximize return on technology investment by leveraging existing technical equity to meet evolving business needs. ...
The 19th International Cloud Expo has announced that its Call for Papers is open. Cloud Expo, to be held November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA, brings together Cloud Computing, Big Data, Internet of Things, DevOps, Digital Transformation, Microservices and WebRTC to one location. With cloud computing driving a higher percentage of enterprise IT budgets every year, it becomes increasingly important to plant your flag in this fast-expanding business opportuni...