Welcome!

News Feed Item

Pocket Science: New Mobile Application Enables DNA Analysis On The Go



Various functions of DNAApp allow handy analysis of DNA sequences
Singapore, May 29, 2014 - (ACN Newswire) - Researchers from A*STAR's Bioinformatics Institute (BII) have developed the first mobile application for Android phones that analyses ab1(1) DNA sequencing files, which enables science professionals and amateur enthusiasts to engage in scientific analysis on the go, from the convenience of their mobile phones.

DNA sequencing is a commonly used technique which has advanced many areas of biological research, from the understanding of genetic information to the causes and treatment of human diseases. However, analysis of DNA sequencing files used to be carried out only on computers. This frustrated Dr Samuel KE Gan, molecular cell biologist and team leader of Antibody & Product Development (APD) Laboratory, when he wanted to work when travelling. He presented the challenge to his computer science research officer Mr Nguyen Phi Vu, to find a better way to read data on the move. What resulted was the "DNAApp", developed in just three months, which allowed him to read and analyse DNA sequencing files on his mobile phone.

Dr Gan's team published the app freely on Google Play store and Apple app store for scientists worldwide so that they too can improve their efficiency and productivity. Since its launch in early April, "DNAApp" has been downloaded more than 300 times by users from more than 11 different countries.

"DNAApp" enables the visualisation and analysis of DNA sequencing files simply with the use of any iOS or Android mobile device. The application lets users assess the quality of DNA sequences and carries out commonly used functions of DNA sequencing analysis, such as reverse complementation, translation, and the ability to search for specific sequences. The latter function is important for researchers who want to locate specific segments in their sequences to identify regions of biological relevance.

Also available for the iOS platform, this native application(2) is faster and more efficient, tapping on the convenience of mobile devices to raise productivity in the lab. The "DNAApp" can work without internet access, and is designed to adapt to the smaller sizes and sensitivity of touch-screen devices. "DNAApp" has features that aid analysis such as the ability to search, swipe or "jump to" a specific section of a sequence and the incorporation of fast and end-scrolling icons. These allow the application to complement existing web-based bioinformatics tools for deeper analysis.

"We are excited to see that 'DNAApp' has proven to be a useful tool for the busy scientist. As the use of mobile devices and their applications become increasingly widespread, we hope to continue to be at the forefront of technology - creating new bioinformatics tools for the advancement of scientific knowledge and making science accessible," said Dr Gan.

Besides the research on antibodies and viral mutations, the laboratory plans to continue developing mobile applications that aid analysis in molecular and microbiology. Like the "DNAApp", these applications will raise productivity in the laboratories and have the added potential to be used as educational tools.

Dr Frank Eisenhaber, Executive Director at BII, said "Thanks to the initiative of Dr. Samuel Gan, the new DNAApp software developed for smart-phones adds an exciting new dimension in the DNA sequence analysis software field. For the first time, a mobile phone application is productive for certain aspects of sequencing data studies. At BII, we will continue to develop creative ideas for useful and efficient tools and techniques in computational biology for applications in the life science field."

(1) ab1 files are data files belonging to the Applied Biosystems Genetic Analysis data file format, and are specific to DNA sequencing. Such files require specific programs that understand their raw data and can represent it as a chromatogram, or visual representation of a sequenced DNA sample.
(2) Native applications are applications that are developed for use on a particular platform. In this case, two versions of DNAApp were created - for the Android and IOS platforms.

About the Bioinformatics Institute (BII)

The Bioinformatics Institute (BII) is an institute of the Agency for Science, Technology and Research (A*STAR). BII was set up in July 2001 as part of the national initiative to foster and advance biomedical research and human capital for a vibrant knowledge-based Singapore. With a multi-disciplinary focus and collaborative outlook, BII recognises the need for depth and breadth in all its activities for building a thriving world-class biomedical research, graduate training and development hub in Singapore. In addition, BII is proactively involved in building a national resource centre in bioinformatics to meet the evolving needs of the scientific community in Singapore. For more information on BII, please visit: www.bii.a-star.edu.sg.

About A*STAR

The Agency for Science, Technology and Research (A*STAR) is Singapore's lead public sector agency that fosters world-class scientific research and talent to drive economic growth and transform Singapore into a vibrant knowledge-based and innovation driven economy.

In line with its mission-oriented mandate, A*STAR spearheads research and development in fields that are essential to growing Singapore's manufacturing sector and catalysing new growth industries. A*STAR supports these economic clusters by providing intellectual, human and industrial capital to its partners in industry.

A*STAR oversees 18 biomedical sciences and physical sciences and engineering research entities, located in Biopolis and Fusionopolis, as well as their vicinity. These two R&D hubs house a bustling and diverse community of local and international research scientists and engineers from A*STAR's research entities as well as a growing number of corporate laboratories. For more information on A*STAR, please visit www.a-star.edu.sg.

Source: A*STAR

Contact:
Vanessa Loh
Senior Officer, Corporate Communications
Agency for Science, Technology and Research
Tel: +65 6826 6395
Email: [email protected]




Copyright 2014 ACN Newswire. All rights reserved.

More Stories By ACN Newswire

Copyright 2008 ACN Newswire. All rights reserved. Republication or redistribution of ACN Newswire content is expressly prohibited without the prior written consent of ACN Newswire. ACN Newswire shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.

Latest Stories
So, you bought into the current machine learning craze and went on to collect millions/billions of records from this promising new data source. Now, what do you do with them? Too often, the abundance of data quickly turns into an abundance of problems. How do you extract that "magic essence" from your data without falling into the common pitfalls? In her session at @ThingsExpo, Natalia Ponomareva, Software Engineer at Google, will provide tips on how to be successful in large scale machine lear...
If there is anything we have learned by now, is that every business paves their own unique path for releasing software- every pipeline, implementation and practices are a bit different, and DevOps comes in all shapes and sizes. Software delivery practices are often comprised of set of several complementing (or even competing) methodologies – such as leveraging Agile, DevOps and even a mix of ITIL, to create the combination that’s most suitable for your organization and that maximize your busines...
Struggling to keep up with increasing application demand? Learn how Platform as a Service (PaaS) can streamline application development processes and make resource management easy.
In his session at @ThingsExpo, Chris Klein, CEO and Co-founder of Rachio, will discuss next generation communities that are using IoT to create more sustainable, intelligent communities. One example is Sterling Ranch, a 10,000 home development that – with the help of Siemens – will integrate IoT technology into the community to provide residents with energy and water savings as well as intelligent security. Everything from stop lights to sprinkler systems to building infrastructures will run ef...
You think you know what’s in your data. But do you? Most organizations are now aware of the business intelligence represented by their data. Data science stands to take this to a level you never thought of – literally. The techniques of data science, when used with the capabilities of Big Data technologies, can make connections you had not yet imagined, helping you discover new insights and ask new questions of your data. In his session at @ThingsExpo, Sarbjit Sarkaria, data science team lead ...
Whether your IoT service is connecting cars, homes, appliances, wearable, cameras or other devices, one question hangs in the balance – how do you actually make money from this service? The ability to turn your IoT service into profit requires the ability to create a monetization strategy that is flexible, scalable and working for you in real-time. It must be a transparent, smoothly implemented strategy that all stakeholders – from customers to the board – will be able to understand and comprehe...
SYS-CON Events announced today that Peak 10, Inc., a national IT infrastructure and cloud services provider, will exhibit at SYS-CON's 18th International Cloud Expo®, which will take place on June 7-9, 2016, at the Javits Center in New York City, NY. Peak 10 provides reliable, tailored data center and network services, cloud and managed services. Its solutions are designed to scale and adapt to customers’ changing business needs, enabling them to lower costs, improve performance and focus inter...
In the world of DevOps there are ‘known good practices’ – aka ‘patterns’ – and ‘known bad practices’ – aka ‘anti-patterns.' Many of these patterns and anti-patterns have been developed from real world experience, especially by the early adopters of DevOps theory; but many are more feasible in theory than in practice, especially for more recent entrants to the DevOps scene. In this power panel at @DevOpsSummit at 18th Cloud Expo, moderated by DevOps Conference Chair Andi Mann, panelists will dis...
See storage differently! Storage performance problems have only gotten worse and harder to solve as applications have become largely virtualized and moved to a cloud-based infrastructure. Storage performance in a virtualized environment is not just about IOPS, it is about how well that potential performance is guaranteed to individual VMs for these apps as the number of VMs keep going up real time. In his session at 18th Cloud Expo, Dhiraj Sehgal, in product and marketing at Tintri, will discu...
Machine Learning helps make complex systems more efficient. By applying advanced Machine Learning techniques such as Cognitive Fingerprinting, wind project operators can utilize these tools to learn from collected data, detect regular patterns, and optimize their own operations. In his session at 18th Cloud Expo, Stuart Gillen, Director of Business Development at SparkCognition, will discuss how research has demonstrated the value of Machine Learning in delivering next generation analytics to im...
Unless you don’t use the internet, don’t live in California, or haven’t been paying attention to the recent news… you should be aware that self-driving cars are on their way to becoming a reality. I have seen them – they are real. If you believe in the future reality of self-driving cars, then continue reading on. If you don’t believe in the future possibilities, then I am not sure what to do to convince you other than discuss the very real changes that will roll out with the consumer producti...
Up until last year, enterprises that were looking into cloud services usually undertook a long-term pilot with one of the large cloud providers, running test and dev workloads in the cloud. With cloud’s transition to mainstream adoption in 2015, and with enterprises migrating more and more workloads into the cloud and in between public and private environments, the single-provider approach must be revisited. In his session at 18th Cloud Expo, Yoav Mor, multi-cloud solution evangelist at Cloudy...
There is an ever-growing explosion of new devices that are connected to the Internet using “cloud” solutions. This rapid growth is creating a massive new demand for efficient access to data. And it’s not just about connecting to that data anymore. This new demand is bringing new issues and challenges and it is important for companies to scale for the coming growth. And with that scaling comes the need for greater security, gathering and data analysis, storage, connectivity and, of course, the...
This is not a small hotel event. It is also not a big vendor party where politicians and entertainers are more important than real content. This is Cloud Expo, the world's longest-running conference and exhibition focused on Cloud Computing and all that it entails. If you want serious presentations and valuable insight about Cloud Computing for three straight days, then register now for Cloud Expo.
IoT device adoption is growing at staggering rates, and with it comes opportunity for developers to meet consumer demand for an ever more connected world. Wireless communication is the key part of the encompassing components of any IoT device. Wireless connectivity enhances the device utility at the expense of ease of use and deployment challenges. Since connectivity is fundamental for IoT device development, engineers must understand how to overcome the hurdles inherent in incorporating multipl...