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Appistry Teams with Personal Genome Diagnostics to Offer CancerSelect™ Test through Appistry CloudDx™
|By Business Wire
|May 30, 2014 02:00 PM EDT
Inc., a leading provider of tools, software, and services
that bring the power of genomics to next-generation medicine, today
announced an agreement with Personal Genome Diagnostics (PGDx) to
include the company’s CancerSelect™ panel in Appistry’s recently
CloudDx™ genomics testing service. PGDx, a provider of
CLIA-compliant genomics services to oncology researchers, drug
developers, clinicians, and patients, is among the first organizations
to offer lab-developed tests (LDTs) through Appistry’s cloud-based
service that makes LDTs from leading diagnostic test providers available
to physicians across the United States. Appistry CloudDx was launched at
the 2014 ASCO Annual Meeting held in Chicago May 30–June 3, 2014.
CancerSelect targets 120 genes of clinical and biological importance to
cancer, providing information that can help physicians individualize
treatment to a patient’s cancer. The CancerSelect panel is sequenced in
PGDx’s CLIA-certified laboratory, and the analysis is conducted using
PGDx’s proprietary algorithms that provide extremely high coverage, copy
number analyses for 63 genes, and translocation analysis for 17 genes.
Appistry will collaborate with PGDx to deliver a report to participating
physicians containing a pathological evaluation of the tumor sample;
tumor-specific mutations (alterations and substitutions, amplifications,
and translocations); a description of mutated genes and pathways along
with biologic and clinical implications; full statistics; and
therapeutic, predictive, and prognostic information and references, as
well as referral information for ongoing clinical trials that might be
relevant based on the analysis results.
Appistry CloudDx streamlines and simplifies the workflow associated with
genomics-based testing, which has been limited in its impact, partly
because it requires organizations to amass infrastructure and expertise
to deliver relevant results that are usable by physicians. Appistry
CloudDx provides a single web dashboard for ordering and tracking the
progress of tests and orchestrates the data flow between test providers
such as PGDx and requesting physicians and hospitals, thereby ensuring
that data and physical samples are transferred and securely managed in
accordance with HIPAA and CLIA guidelines.
“PGDx is committed to applying the latest genomics technology to deliver
comprehensive, reliable, unbiased analyses of cancer-related mutations,”
said Antony Newton, chief commercial officer at PGDx. “Making
CancerSelect available through Appistry CloudDx will extend our reach,
enabling our panel to be utilized more broadly by community physicians
looking to provide the best diagnostic and treatment options to their
“Appistry’s aim is to enable physicians everywhere to implement genomics-based
tests, regardless of geography, institutional size, or medical
system affiliation,” said Kevin Haar, chief executive officer of
Appistry. “We are excited that PGDx’s CancerSelect test will be
available as the first offering in Appistry CloudDx, as it is a great
example of the type of high-quality, leading-edge medicine that
physicians need in order to deliver genomically enhanced medicine to
Appistry will be demonstrating CloudDx at Booth #16152 at the 2014 ASCO
Annual Meeting in Chicago May 30–June 3, 2014. More information about
Appistry CloudDx can be found at appistry.com/gem.
More information about CancerSelect can be found at personalgenome.com/cancerselect.
Inc., brings the power of genomics to next-generation medicine by
making genomics data easier for researchers and clinicians to act on.
Appistry CloudDx provides cost-effective access to established,
laboratory developed tests so that clinically relevant genomics-based
information can be usable by any physician, anywhere. Appistry also
empowers researchers by providing world-class bioinformatics tools,
cloud services, and software that streamline the analysis of
next-generation sequencing data and provide easy scale for moving
research-developed pipelines into production. Learn more by connecting
with Appistry on Facebook,
About Personal Genome Diagnostics
Personal Genome Diagnostics (PGDx) provides advanced cancer genome
analyses to oncology researchers, drug developers, clinicians and
patients. The company uses advanced genomic methods and its deep
expertise in cancer biology to identify and characterize the unique
genomic alterations in tumors. PGDx’s proprietary methods for genome
sequencing and analysis are complemented by its extensive experience in
cancer genomics and clinical oncology. The founders of PGDx, Luis Diaz,
MD, and Victor Velculescu, MD, PhD, are internationally recognized
leaders in cancer genomics at Johns Hopkins University who have
extensive experience in the practical application of advanced genomic
technologies to drug development and clinical practice. PGDx’s
CLIA-certified facility provides personalized cancer genome analyses to
patients and their physicians. For more information, visit www.personalgenome.com.
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