Click here to close now.

Welcome!

News Feed Item

The American Journal of Managed Care Publishes Results Showing Big Data Analytics Can Predict Individualized Risk of Metabolic Syndrome in Patients

Research published today in The American Journal of Managed Care demonstrates that analysis of patient records using state-of-the-art data analytics can predict future risk of metabolic syndrome. More than a third of the U.S. population has metabolic syndrome, a condition that can lead to chronic heart disease, stroke and diabetes. These conditions combine to account for almost 20 percent of overall health care costs in the U.S. The study was conducted by Aetna (NYSE: AET) and GNS Healthcare Inc. (GNS), a leading provider of big data analytics products and services in health care.

“This study demonstrates how integration of multiple sources of patient data can help predict patient-specific medical problems,” said lead author Dr. Gregory Steinberg, head of clinical innovation at Aetna Innovation Labs. “We believe the personalized clinical outreach and engagement strategies, informed by data from this study, can help improve the health of people with metabolic syndrome and reduce the associated costs.”

“The breakthrough in this study is that we are able to bring to light hyper-individualized patient predictions, including quantitatively identifying which individual patients are most at risk, which syndrome factors are most likely to push that patient past a threshold, and which interventions will have the greatest impact on that individual,” said Colin Hill, co-founder and CEO of GNS. “The GNS automated data analytics platform paired with Aetna’s deep clinical expertise produced these results on extremely large datasets in just three months, a testament to the ability of both groups.”

GNS analyzed data from nearly 37,000 members of one of Aetna’s employer customers who had voluntarily participated in screening for metabolic syndrome. The data analyzed included medical claims records, demographics, pharmacy claims, lab tests and biometric screening results over a two-year period. For this study, the Aetna and GNS teams utilized two distinct analytical models:

  • A claims-based-only model to predict the probability of each of the five metabolic syndrome factors occurring for each study subject.
  • A second model based on both claims and biometric data to predict whether each study subject is likely to get worse, improve or stay the same for each metabolic syndrome factor.

Both analytical models predicted future risk of metabolic syndrome on both a population and an individual level, with ROC/AUC (receiver operating characteristic/area under the curve) varying from 0.80 and 0.88. The researchers were able to develop detailed risk profiles for individual participants, enabling a deep understanding of exactly which combination of the five metabolic syndrome factors each of the study subjects exhibit and are at risk for developing. For every Aetna member whose data was used in the study, the researchers used a scale that measures the percentage risk that individuals have of exhibiting each of the five metabolic syndrome factors. For example, in an individual patient who exhibited two of the five risk factors, researchers could predict which third factor is the most likely to develop.

The analytical models also helped identify individual variable impact on risk associated with adherence to prescribed medications, as well as adherence to routine, scheduled outpatient doctor visits. A scheduled, outpatient visit with a primary care physician lowers the one-year probability of having metabolic syndrome in nearly 90 percent of individuals. In addition, the study found that improving waist circumference and blood glucose yielded the largest benefits on patients’ subsequent risk and medical costs.

Click here to access the entire article on The American Journal of Managed Care website.

About Metabolic Syndrome

Metabolic syndrome is a group of risk factors: large waist size, high blood pressure, high triglycerides, low high-density lipoprotein (HDL)—or “good”—cholesterol and high blood sugar. Patients who exhibit three of these five factors are classified as having metabolic syndrome. Individuals who have metabolic syndrome are twice as likely to have a heart attack or stroke and are five times as likely to develop diabetes as those who do not. The rate of metabolic syndrome is on the rise, with over a third of U.S. adults having the condition. The chronic diseases that metabolic syndrome can lead to–heart disease, stroke and diabetes–together cause nearly 800,000 deaths per year in the U.S., alone. These diseases cost the health care system more than half a trillion dollars, or almost 20 percent of the $2.7 trillion the U.S. Centers for Disease Control and Prevention cites as the total cost of national health expenditures. (Sources: American Heart Association and American Diabetes Association)

About GNS Healthcare

GNS Healthcare is a big data analytics company that empowers payers, providers and pharmaceutical companies to make intelligent data-driven decisions. We unlock knowledge within complex data, enabling personalized, actionable predictions and precision targeting. For 15 years, GNS has been committed to developing and deploying the most sophisticated mathematical and computational platforms to help our partners improve health and reduce costs. www.GNSHealthcare.com

About Aetna

Aetna is one of the nation’s leading diversified health care benefits companies, serving an estimated 44 million people with information and resources to help them make better informed decisions about their health care. Aetna offers a broad range of traditional, voluntary and consumer-directed health insurance products and related services, including medical, pharmacy, dental, behavioral health, group life and disability plans, and medical management capabilities, Medicaid health care management services, workers’ compensation administrative services and health information technology products and services. Aetna’s customers include employer groups, individuals, college students, part-time and hourly workers, health plans, health care providers, governmental units, government-sponsored plans, labor groups and expatriates. For more information, see www.Aetna.com and the 2014 Aetna story about how Aetna is helping to build a healthier world.

More Stories By Business Wire

Copyright © 2009 Business Wire. All rights reserved. Republication or redistribution of Business Wire content is expressly prohibited without the prior written consent of Business Wire. Business Wire shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.

Latest Stories
In the midst of the widespread popularity and adoption of cloud computing, it seems like everything is being offered “as a Service” these days: Infrastructure? Check. Platform? You bet. Software? Absolutely. Toaster? It’s only a matter of time. With service providers positioning vastly differing offerings under a generic “cloud” umbrella, it’s all too easy to get confused about what’s actually being offered. In his session at 16th Cloud Expo, Kevin Hazard, Director of Digital Content for SoftL...
Agile, which started in the development organization, has gradually expanded into other areas downstream - namely IT and Operations. Teams – then teams of teams – have streamlined processes, improved feedback loops and driven a much faster pace into IT departments which have had profound effects on the entire organization. In his session at DevOps Summit, Anders Wallgren, Chief Technology Officer of Electric Cloud, will discuss how DevOps and Continuous Delivery have emerged to help connect dev...
Today air travel is a minefield of delays, hassles and customer disappointment. Airlines struggle to revitalize the experience. GE and M2Mi will demonstrate practical examples of how IoT solutions are helping airlines bring back personalization, reduce trip time and improve reliability. In their session at @ThingsExpo, Shyam Varan Nath, Principal Architect with GE, and Dr. Sarah Cooper, M2Mi’s VP Business Development and Engineering, will explore the IoT cloud-based platform technologies drivi...
Containers are changing the security landscape for software development and deployment. As with any security solutions, security approaches that work for developers, operations personnel and security professionals is a requirement. In his session at DevOps Summit, Kevin Gilpin, CTO and Co-Founder of Conjur, will discuss various security considerations for container-based infrastructure and related DevOps workflows.
It is one thing to build single industrial IoT applications, but what will it take to build the Smart Cities and truly society-changing applications of the future? The technology won’t be the problem, it will be the number of parties that need to work together and be aligned in their motivation to succeed. In his session at @ThingsExpo, Jason Mondanaro, Director, Product Management at Metanga, discussed how you can plan to cooperate, partner, and form lasting all-star teams to change the world...
Overgrown applications have given way to modular applications, driven by the need to break larger problems into smaller problems. Similarly large monolithic development processes have been forced to be broken into smaller agile development cycles. Looking at trends in software development, microservices architectures meet the same demands. Additional benefits of microservices architectures are compartmentalization and a limited impact of service failure versus a complete software malfunction. ...
Internet of Things is moving from being a hype to a reality. Experts estimate that internet connected cars will grow to 152 million, while over 100 million internet connected wireless light bulbs and lamps will be operational by 2020. These and many other intriguing statistics highlight the importance of Internet powered devices and how market penetration is going to multiply many times over in the next few years.
Internet of Things (IoT) will be a hybrid ecosystem of diverse devices and sensors collaborating with operational and enterprise systems to create the next big application. In their session at @ThingsExpo, Bramh Gupta, founder and CEO of robomq.io, and Fred Yatzeck, principal architect leading product development at robomq.io, discussed how choosing the right middleware and integration strategy from the get-go will enable IoT solution developers to adapt and grow with the industry, while at th...
Containers have changed the mind of IT in DevOps. They enable developers to work with dev, test, stage and production environments identically. Containers provide the right abstraction for microservices and many cloud platforms have integrated them into deployment pipelines. DevOps and Containers together help companies to achieve their business goals faster and more effectively. In his session at DevOps Summit, Ruslan Synytsky, CEO and Co-founder of Jelastic, reviewed the current landscape of...
Malicious agents are moving faster than the speed of business. Even more worrisome, most companies are relying on legacy approaches to security that are no longer capable of meeting current threats. In the modern cloud, threat diversity is rapidly expanding, necessitating more sophisticated security protocols than those used in the past or in desktop environments. Yet companies are falling for cloud security myths that were truths at one time but have evolved out of existence.
The cloud has transformed how we think about software quality. Instead of preventing failures, we must focus on automatic recovery from failure. In other words, resilience trumps traditional quality measures. Continuous delivery models further squeeze traditional notions of quality. Remember the venerable project management Iron Triangle? Among time, scope, and cost, you can only fix two or quality will suffer. Only in today's DevOps world, continuous testing, integration, and deployment upend...
The time is ripe for high speed resilient software defined storage solutions with unlimited scalability. ISS has been working with the leading open source projects and developed a commercial high performance solution that is able to grow forever without performance limitations. In his session at Cloud Expo, Alex Gorbachev, President of Intelligent Systems Services Inc., shared foundation principles of Ceph architecture, as well as the design to deliver this storage to traditional SAN storage co...
To many people, IoT is a buzzword whose value is not understood. Many people think IoT is all about wearables and home automation. In his session at @ThingsExpo, Mike Kavis, Vice President & Principal Cloud Architect at Cloud Technology Partners, discussed some incredible game-changing use cases and how they are transforming industries like agriculture, manufacturing, health care, and smart cities. He will discuss cool technologies like smart dust, robotics, smart labels, and much more. Prepare...
"We provide a web application framework for building really sophisticated web applications that run on a browser without any installation need so we get used for biotech, defense, and banking applications," noted Charles Kendrick, CTO and Chief Architect at Isomorphic Software, in this SYS-CON.tv interview at @DevOpsSummit (http://DevOpsSummit.SYS-CON.com), held June 9-11, 2015, at the Javits Center in New York
The Internet of Things is not only adding billions of sensors and billions of terabytes to the Internet. It is also forcing a fundamental change in the way we envision Information Technology. For the first time, more data is being created by devices at the edge of the Internet rather than from centralized systems. What does this mean for today's IT professional? In this Power Panel at @ThingsExpo, moderated by Conference Chair Roger Strukhoff, panelists addressed this very serious issue of pro...