Welcome!

News Feed Item

The American Journal of Managed Care Publishes Results Showing Big Data Analytics Can Predict Individualized Risk of Metabolic Syndrome in Patients

Research published today in The American Journal of Managed Care demonstrates that analysis of patient records using state-of-the-art data analytics can predict future risk of metabolic syndrome. More than a third of the U.S. population has metabolic syndrome, a condition that can lead to chronic heart disease, stroke and diabetes. These conditions combine to account for almost 20 percent of overall health care costs in the U.S. The study was conducted by Aetna (NYSE: AET) and GNS Healthcare Inc. (GNS), a leading provider of big data analytics products and services in health care.

“This study demonstrates how integration of multiple sources of patient data can help predict patient-specific medical problems,” said lead author Dr. Gregory Steinberg, head of clinical innovation at Aetna Innovation Labs. “We believe the personalized clinical outreach and engagement strategies, informed by data from this study, can help improve the health of people with metabolic syndrome and reduce the associated costs.”

“The breakthrough in this study is that we are able to bring to light hyper-individualized patient predictions, including quantitatively identifying which individual patients are most at risk, which syndrome factors are most likely to push that patient past a threshold, and which interventions will have the greatest impact on that individual,” said Colin Hill, co-founder and CEO of GNS. “The GNS automated data analytics platform paired with Aetna’s deep clinical expertise produced these results on extremely large datasets in just three months, a testament to the ability of both groups.”

GNS analyzed data from nearly 37,000 members of one of Aetna’s employer customers who had voluntarily participated in screening for metabolic syndrome. The data analyzed included medical claims records, demographics, pharmacy claims, lab tests and biometric screening results over a two-year period. For this study, the Aetna and GNS teams utilized two distinct analytical models:

  • A claims-based-only model to predict the probability of each of the five metabolic syndrome factors occurring for each study subject.
  • A second model based on both claims and biometric data to predict whether each study subject is likely to get worse, improve or stay the same for each metabolic syndrome factor.

Both analytical models predicted future risk of metabolic syndrome on both a population and an individual level, with ROC/AUC (receiver operating characteristic/area under the curve) varying from 0.80 and 0.88. The researchers were able to develop detailed risk profiles for individual participants, enabling a deep understanding of exactly which combination of the five metabolic syndrome factors each of the study subjects exhibit and are at risk for developing. For every Aetna member whose data was used in the study, the researchers used a scale that measures the percentage risk that individuals have of exhibiting each of the five metabolic syndrome factors. For example, in an individual patient who exhibited two of the five risk factors, researchers could predict which third factor is the most likely to develop.

The analytical models also helped identify individual variable impact on risk associated with adherence to prescribed medications, as well as adherence to routine, scheduled outpatient doctor visits. A scheduled, outpatient visit with a primary care physician lowers the one-year probability of having metabolic syndrome in nearly 90 percent of individuals. In addition, the study found that improving waist circumference and blood glucose yielded the largest benefits on patients’ subsequent risk and medical costs.

Click here to access the entire article on The American Journal of Managed Care website.

About Metabolic Syndrome

Metabolic syndrome is a group of risk factors: large waist size, high blood pressure, high triglycerides, low high-density lipoprotein (HDL)—or “good”—cholesterol and high blood sugar. Patients who exhibit three of these five factors are classified as having metabolic syndrome. Individuals who have metabolic syndrome are twice as likely to have a heart attack or stroke and are five times as likely to develop diabetes as those who do not. The rate of metabolic syndrome is on the rise, with over a third of U.S. adults having the condition. The chronic diseases that metabolic syndrome can lead to–heart disease, stroke and diabetes–together cause nearly 800,000 deaths per year in the U.S., alone. These diseases cost the health care system more than half a trillion dollars, or almost 20 percent of the $2.7 trillion the U.S. Centers for Disease Control and Prevention cites as the total cost of national health expenditures. (Sources: American Heart Association and American Diabetes Association)

About GNS Healthcare

GNS Healthcare is a big data analytics company that empowers payers, providers and pharmaceutical companies to make intelligent data-driven decisions. We unlock knowledge within complex data, enabling personalized, actionable predictions and precision targeting. For 15 years, GNS has been committed to developing and deploying the most sophisticated mathematical and computational platforms to help our partners improve health and reduce costs. www.GNSHealthcare.com

About Aetna

Aetna is one of the nation’s leading diversified health care benefits companies, serving an estimated 44 million people with information and resources to help them make better informed decisions about their health care. Aetna offers a broad range of traditional, voluntary and consumer-directed health insurance products and related services, including medical, pharmacy, dental, behavioral health, group life and disability plans, and medical management capabilities, Medicaid health care management services, workers’ compensation administrative services and health information technology products and services. Aetna’s customers include employer groups, individuals, college students, part-time and hourly workers, health plans, health care providers, governmental units, government-sponsored plans, labor groups and expatriates. For more information, see www.Aetna.com and the 2014 Aetna story about how Aetna is helping to build a healthier world.

More Stories By Business Wire

Copyright © 2009 Business Wire. All rights reserved. Republication or redistribution of Business Wire content is expressly prohibited without the prior written consent of Business Wire. Business Wire shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.

Latest Stories
The essence of cloud computing is that all consumable IT resources are delivered as services. In his session at 15th Cloud Expo, Yung Chou, Technology Evangelist at Microsoft, demonstrated the concepts and implementations of two important cloud computing deliveries: Infrastructure as a Service (IaaS) and Platform as a Service (PaaS). He discussed from business and technical viewpoints what exactly they are, why we care, how they are different and in what ways, and the strategies for IT to transi...
The Internet of Things is clearly many things: data collection and analytics, wearables, Smart Grids and Smart Cities, the Industrial Internet, and more. Cool platforms like Arduino, Raspberry Pi, Intel's Galileo and Edison, and a diverse world of sensors are making the IoT a great toy box for developers in all these areas. In this Power Panel at @ThingsExpo, moderated by Conference Chair Roger Strukhoff, panelists discussed what things are the most important, which will have the most profound e...
All organizations that did not originate this moment have a pre-existing culture as well as legacy technology and processes that can be more or less amenable to DevOps implementation. That organizational culture is influenced by the personalities and management styles of Executive Management, the wider culture in which the organization is situated, and the personalities of key team members at all levels of the organization. This culture and entrenched interests usually throw a wrench in the work...
Keeping pace with advancements in software delivery processes and tooling is taxing even for the most proficient organizations. Point tools, platforms, open source and the increasing adoption of private and public cloud services requires strong engineering rigor - all in the face of developer demands to use the tools of choice. As Agile has settled in as a mainstream practice, now DevOps has emerged as the next wave to improve software delivery speed and output. To make DevOps work, organization...
My team embarked on building a data lake for our sales and marketing data to better understand customer journeys. This required building a hybrid data pipeline to connect our cloud CRM with the new Hadoop Data Lake. One challenge is that IT was not in a position to provide support until we proved value and marketing did not have the experience, so we embarked on the journey ourselves within the product marketing team for our line of business within Progress. In his session at @BigDataExpo, Sum...
Niagara Networks exhibited at the 19th International Cloud Expo, which took place at the Santa Clara Convention Center in Santa Clara, CA, in November 2016. Niagara Networks offers the highest port-density systems, and the most complete Next-Generation Network Visibility systems including Network Packet Brokers, Bypass Switches, and Network TAPs.
Virtualization over the past years has become a key strategy for IT to acquire multi-tenancy, increase utilization, develop elasticity and improve security. And virtual machines (VMs) are quickly becoming a main vehicle for developing and deploying applications. The introduction of containers seems to be bringing another and perhaps overlapped solution for achieving the same above-mentioned benefits. Are a container and a virtual machine fundamentally the same or different? And how? Is one techn...
Extreme Computing is the ability to leverage highly performant infrastructure and software to accelerate Big Data, machine learning, HPC, and Enterprise applications. High IOPS Storage, low-latency networks, in-memory databases, GPUs and other parallel accelerators are being used to achieve faster results and help businesses make better decisions. In his session at 18th Cloud Expo, Michael O'Neill, Strategic Business Development at NVIDIA, focused on some of the unique ways extreme computing is...
Web Real-Time Communication APIs have quickly revolutionized what browsers are capable of. In addition to video and audio streams, we can now bi-directionally send arbitrary data over WebRTC's PeerConnection Data Channels. With the advent of Progressive Web Apps and new hardware APIs such as WebBluetooh and WebUSB, we can finally enable users to stitch together the Internet of Things directly from their browsers while communicating privately and securely in a decentralized way.
Information technology (IT) advances are transforming the way we innovate in business, thereby disrupting the old guard and their predictable status-quo. It’s creating global market turbulence. Industries are converging, and new opportunities and threats are emerging, like never before. So, how are savvy chief information officers (CIOs) leading this transition? Back in 2015, the IBM Institute for Business Value conducted a market study that included the findings from over 1,800 CIO interviews ...
"We host and fully manage cloud data services, whether we store, the data, move the data, or run analytics on the data," stated Kamal Shannak, Senior Development Manager, Cloud Data Services, IBM, in this SYS-CON.tv interview at 18th Cloud Expo, held June 7-9, 2016, at the Javits Center in New York City, NY.
DevOps is often described as a combination of technology and culture. Without both, DevOps isn't complete. However, applying the culture to outdated technology is a recipe for disaster; as response times grow and connections between teams are delayed by technology, the culture will die. A Nutanix Enterprise Cloud has many benefits that provide the needed base for a true DevOps paradigm.
What sort of WebRTC based applications can we expect to see over the next year and beyond? One way to predict development trends is to see what sorts of applications startups are building. In his session at @ThingsExpo, Arin Sime, founder of WebRTC.ventures, will discuss the current and likely future trends in WebRTC application development based on real requests for custom applications from real customers, as well as other public sources of information,
Interoute has announced the integration of its Global Cloud Infrastructure platform with Rancher Labs’ container management platform, Rancher. This approach enables enterprises to accelerate their digital transformation and infrastructure investments. Matthew Finnie, Interoute CTO commented “Enterprises developing and building apps in the cloud and those on a path to Digital Transformation need Digital ICT Infrastructure that allows them to build, test and deploy faster than ever before. The int...
Whether you like it or not, DevOps is on track for a remarkable alliance with security. The SEC didn’t approve the merger. And your boss hasn’t heard anything about it. Yet, this unruly triumvirate will soon dominate and deliver DevSecOps faster, cheaper, better, and on an unprecedented scale. In his session at DevOps Summit, Frank Bunger, VP of Customer Success at ScriptRock, discussed how this cathartic moment will propel the DevOps movement from such stuff as dreams are made on to a practic...