Welcome!

News Feed Item

Overcoming Light Scattering: Single-pixel Optical System Uses Compressive Sensing to See Deeper Inside Tissue

Optical imaging methods are rapidly becoming essential tools in biomedical science because they’re noninvasive, fast, cost-efficient and pose no health risks since they don't use ionizing radiation. These methods could become even more valuable if researchers could find a way for optical light to penetrate all the way through the body's tissues. With today’s technology, even passing through a fraction of an inch of skin is enough to scatter the light and scramble the image.

Now a team of researchers from Spain’s Jaume I University (UJI) and the University of València has developed a single-pixel optical system based on compressive sensing that can overcome the fundamental limitations imposed by this scattering. The work was published today in The Optical Society’s (OSA) open-access journal Optics Express.

“In the diagnostic realm within the past few years, we’ve witnessed the way optical imaging has helped clinicians detect and evaluate suspicious lesions," said Jesús Lancis, the paper’s co-author and a researcher in the Photonics Research Group at UJI. "The elephant in the room, however, is the question of the short penetration depth of light within tissue compared to ultrasound or x-ray technologies. Current knowledge is insufficient for early detection of small lesions located deeper than a millimeter beneath the surface of the mucosa."

"Our goal is to see deeper inside tissue,” he added.

To achieve this, the team used an off-the-shelf digital micromirror array from a commercial video projector to create a set of microstructured light patterns that are sequentially superimposed onto a sample. They then measure the transmitted energy with a photodetector that can sense the presence or absence of light, but has no spatial resolution. Then they apply a signal processing technique called compressive sensing, which is used to compress large data files as they are measured. This allows them to reconstruct the image.

One of the most surprising aspects of the team’s work is that they use essentially a single-pixel sensor to capture the images. While most people think that more pixels result in better image quality, there are some cases where this isn't true, Lancis said. In low-light imaging, for instance, it's better to integrate all available light into a single sensor. If the light is split into millions of pixels, each sensor receives a tiny fraction of light, creating noise and destroying the image.

“Something similar happens when you try to transmit images through scattering media,” Lancis said. “When we use a conventional digital camera to get an image, we only see the familiar noisy pattern known as ‘speckle.’ In compressive imaging, since we aren’t using pixelated sensors, it should be less sensitive to light scrambling and enable transmission of images through scattering.”

Also notable, the team’s technique could operate through dynamic scattering. “Most scattering media of interest, like biological tissue, are dynamic in the sense that the scatter centers continuously change their positions with time -- meaning that the speckle patterns are ‘in motion.’ This is ideal for some applications because monitoring the changes of the speckle can reveal information about the sample, but the drawback is that it’s a major nuisance to transmit or get images,” Lancis pointed out. “Our technique, however, requires no calibration of the medium, and its fluctuations during the sensing stage don’t limit imaging ability.”

What’s ahead for the team? “Our next goal is to break the barriers of light penetration depth inside a scattering medium with the state-of-the-art megapixel-programmable spatial light modulators used in consumer electronics,” Lancis says. To do this, they’ll need to demonstrate that their technique works even when the sample is embedded inside the tissue.

Paper: “Image transmission through dynamic scattering media by single-pixel photodetection,” E. Tajahuerce et al., Optics Express, Vol. 22, Issue 14, pp. 16945-16955 (2014).

EDITOR’S NOTE: Images and video are available to members of the media upon request. Contact Angela Stark, [email protected].

About Optics Express

Optics Express reports on new developments in all fields of optical science and technology every two weeks. The journal provides rapid publication of original, peer-reviewed papers. It is published by The Optical Society and edited by Andrew M. Weiner of Purdue University. Optics Express is an open-access journal and is available at no cost to readers online at www.OpticsInfoBase.org/OE.

About OSA

Founded in 1916, The Optical Society (OSA) is the leading professional society for scientists, engineers, students and business leaders who fuel discoveries, shape real-world applications and accelerate achievements in the science of light. Through world-renowned publications, meetings and membership programs, OSA provides quality research, inspired interactions and dedicated resources for its extensive global network of professionals in optics and photonics. For more information, visit www.osa.org.

More Stories By Business Wire

Copyright © 2009 Business Wire. All rights reserved. Republication or redistribution of Business Wire content is expressly prohibited without the prior written consent of Business Wire. Business Wire shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.

Latest Stories
Multiple data types are pouring into IoT deployments. Data is coming in small packages as well as enormous files and data streams of many sizes. Widespread use of mobile devices adds to the total. In this power panel at @ThingsExpo, moderated by Conference Chair Roger Strukhoff, panelists looked at the tools and environments that are being put to use in IoT deployments, as well as the team skills a modern enterprise IT shop needs to keep things running, get a handle on all this data, and deliver...
SYS-CON Events announced today that Enzu will exhibit at SYS-CON's 21st Int\ernational Cloud Expo®, which will take place October 31-November 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA. Enzu’s mission is to be the leading provider of enterprise cloud solutions worldwide. Enzu enables online businesses to use its IT infrastructure to their competitive advantage. By offering a suite of proven hosting and management services, Enzu wants companies to focus on the core of their ...
"We are a monitoring company. We work with Salesforce, BBC, and quite a few other big logos. We basically provide monitoring for them, structure for their cloud services and we fit into the DevOps world" explained David Gildeh, Co-founder and CEO of Outlyer, in this SYS-CON.tv interview at DevOps Summit at 20th Cloud Expo, held June 6-8, 2017, at the Javits Center in New York City, NY.
We build IoT infrastructure products - when you have to integrate different devices, different systems and cloud you have to build an application to do that but we eliminate the need to build an application. Our products can integrate any device, any system, any cloud regardless of protocol," explained Peter Jung, Chief Product Officer at Pulzze Systems, in this SYS-CON.tv interview at @ThingsExpo, held November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA
SYS-CON Events announced today that GrapeUp, the leading provider of rapid product development at the speed of business, will exhibit at SYS-CON's 21st International Cloud Expo®, which will take place October 31-November 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA. Grape Up is a software company, specialized in cloud native application development and professional services related to Cloud Foundry PaaS. With five expert teams that operate in various sectors of the market acr...
SYS-CON Events announced today that IBM has been named “Diamond Sponsor” of SYS-CON's 21st Cloud Expo, which will take place on October 31 through November 2nd 2017 at the Santa Clara Convention Center in Santa Clara, California.
In 2014, Amazon announced a new form of compute called Lambda. We didn't know it at the time, but this represented a fundamental shift in what we expect from cloud computing. Now, all of the major cloud computing vendors want to take part in this disruptive technology. In his session at 20th Cloud Expo, Doug Vanderweide, an instructor at Linux Academy, discussed why major players like AWS, Microsoft Azure, IBM Bluemix, and Google Cloud Platform are all trying to sidestep VMs and containers wit...
SYS-CON Events announced today that Ayehu will exhibit at SYS-CON's 21st International Cloud Expo®, which will take place on October 31 - November 2, 2017 at the Santa Clara Convention Center in Santa Clara California. Ayehu provides IT Process Automation & Orchestration solutions for IT and Security professionals to identify and resolve critical incidents and enable rapid containment, eradication, and recovery from cyber security breaches. Ayehu provides customers greater control over IT infras...
The financial services market is one of the most data-driven industries in the world, yet it’s bogged down by legacy CPU technologies that simply can’t keep up with the task of querying and visualizing billions of records. In his session at 20th Cloud Expo, Karthik Lalithraj, a Principal Solutions Architect at Kinetica, discussed how the advent of advanced in-database analytics on the GPU makes it possible to run sophisticated data science workloads on the same database that is housing the rich...
SYS-CON Events announced today that CA Technologies has been named "Platinum Sponsor" of SYS-CON's 21st International Cloud Expo®, which will take place October 31-November 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA. CA Technologies helps customers succeed in a future where every business - from apparel to energy - is being rewritten by software. From planning to development to management to security, CA creates software that fuels transformation for companies in the applic...
New competitors, disruptive technologies, and growing expectations are pushing every business to both adopt and deliver new digital services. This ‘Digital Transformation’ demands rapid delivery and continuous iteration of new competitive services via multiple channels, which in turn demands new service delivery techniques – including DevOps. In this power panel at @DevOpsSummit 20th Cloud Expo, moderated by DevOps Conference Co-Chair Andi Mann, panelists examined how DevOps helps to meet the de...
With major technology companies and startups seriously embracing Cloud strategies, now is the perfect time to attend 21st Cloud Expo October 31 - November 2, 2017, at the Santa Clara Convention Center, CA, and June 12-14, 2018, at the Javits Center in New York City, NY, and learn what is going on, contribute to the discussions, and ensure that your enterprise is on the right path to Digital Transformation.
SYS-CON Events announced today that MobiDev, a client-oriented software development company, will exhibit at SYS-CON's 21st International Cloud Expo®, which will take place October 31-November 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA. MobiDev is a software company that develops and delivers turn-key mobile apps, websites, web services, and complex software systems for startups and enterprises. Since 2009 it has grown from a small group of passionate engineers and business...
Automation is enabling enterprises to design, deploy, and manage more complex, hybrid cloud environments. Yet the people who manage these environments must be trained in and understanding these environments better than ever before. A new era of analytics and cognitive computing is adding intelligence, but also more complexity, to these cloud environments. How smart is your cloud? How smart should it be? In this power panel at 20th Cloud Expo, moderated by Conference Chair Roger Strukhoff, pane...
Cloud Expo, Inc. has announced today that Andi Mann and Aruna Ravichandran have been named Co-Chairs of @DevOpsSummit at Cloud Expo Silicon Valley which will take place Oct. 31-Nov. 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA. "DevOps is at the intersection of technology and business-optimizing tools, organizations and processes to bring measurable improvements in productivity and profitability," said Aruna Ravichandran, vice president, DevOps product and solutions marketing...