Welcome!

News Feed Item

Taconic Announces New Agreement to Distribute Next Generation NOG Mouse Models

HUDSON, NY -- (Marketwired) -- 07/23/14 -- Taconic announced today that it has finalized a distribution and licensing agreement with the Central Institute for Experimental Animals (CIEA) and In-Vivo Science International Inc. (IVSI) that grants Taconic exclusive rights to commercialize up to thirty strains of next generation NOG mice models in the United States, Europe and Australia. The agreement also allows Taconic to perform human cell engraftment and other services using next generation NOG models. The first three new models in the NOG Portfolio™ are now available and others will be introduced in 2014-15.

The agreement is an important milestone in Taconic's tissue and cell-based mouse humanization programs. Samuel Phelan, Chairman of the Board of Directors at Taconic, comments on the significance of the new agreement: "Taconic is excited about the expansion of our partnership with CIEA and IVSI to make up to thirty new NOG mouse lines available to biomedical and biopharmaceutical researchers. The addition of new models to our NOG Portfolio represents the next phase in Taconic's mission to develop better, more predictive models for use by scientists worldwide. This agreement allows us to further our cell and tissue-based humanization program, which will result in several new NOG models being made available to the scientific community."

The CIEA NOG mouse® is a super immunodeficient model that was developed and extensively characterized in the laboratory by Dr. Mamoru Ito at CIEA. It is used by researchers involved mainly in immunology, oncology, and infectious disease research. Given its excellent performance in the engraftment of human cells and tissues, the NOG is ideal for human immune system reconstitution. Additional genetic modifications made in the next generation of NOG Portfolio™ mice will lead to enhancements of specific cell lineages and overall improvements in the functionality of the reconstituted human immune system.

Ryuta Nomura, Executive Director of CIEA, believes that the agreement with Taconic will build upon the successes of the CIEA NOG mouse®. "CIEA is proud to have Taconic as its commercialization partner for the additional NOG lines in Europe, the United States, and Australia. Together we have distributed the super immunodeficient CIEA NOG mouse® to investigators worldwide who are involved in vital research. Now we will do the same with Dr. Ito's improved models through our agreement with Taconic."

Through internal research efforts as well as collaborations with scientists worldwide, CIEA and Taconic anticipate that the next generation NOG models will be recognized as key research tools that are better able to mimic human biology following the engraftment of human cells and tissues, thereby providing greater predictability of the human response to treatment.

Among the newly released models are the TK-NOG for reconstitution of the human liver and immune system, the hGM-CSF/hIL-3Tg for enhanced engraftment of myeloid cell lineages, and the beta2m Knockout NOG for delayed onset of GvHD following PBMC engraftment. More information about particular NOG models that will be released is available by contacting Taconic: USA +1 888-822-6642 | Europe: +45 70 23 04 05.

About Taconic

Taconic is a global provider of genetically engineered mouse and rat models and services. As a full-service industry leader, founded in 1952, Taconic helps clients acquire, custom generate, breed, test, prepare, and distribute highly relevant research lines worldwide. Headquartered in New York's Hudson River Valley, Taconic operates breeding facilities and service laboratories in the U.S. and Europe. The company employs over 850 employees committed to technological innovation. Taconic's products and services are used by over 1,300 companies and academic research institutions in nearly 50 nations worldwide. For further information, please visit http://www.taconic.com/nog-portfolio

About CIEA

The Central Institute for Experimental Animals (CIEA) was established in 1952 by Dr. Tatsuji Nomura. Today, the CIEA contributes to the health and welfare of humankind through development of validated humanized animals with stable, reproducible phenotypes. The CIEA also contributes to the research of human diseases and clarification of their causes through the use of laboratory animals as in vivo standards of measurement. The CIEA pursues to create various innovative industrial foundation skills that contribute to the competitive power of Japan. Specifically, the CIEA will actively support the incubation of various venture businesses with advanced know-how but insufficient capital. At the same time, the CIEA will also reinforce its exchange of research resources and information with various international corporations and research institutes. For more information go to: http://www.ciea.or.jp/en

About IVSI

IVSI is an independent business promotion company for in vivo studies. IVSI was granted the exclusive license from CIEA to produce and distribute NOG mice, and next generation NOG mice.

More Stories By Marketwired .

Copyright © 2009 Marketwired. All rights reserved. All the news releases provided by Marketwired are copyrighted. Any forms of copying other than an individual user's personal reference without express written permission is prohibited. Further distribution of these materials is strictly forbidden, including but not limited to, posting, emailing, faxing, archiving in a public database, redistributing via a computer network or in a printed form.

Latest Stories
Blockchain. A day doesn’t seem to go by without seeing articles and discussions about the technology. According to PwC executive Seamus Cushley, approximately $1.4B has been invested in blockchain just last year. In Gartner’s recent hype cycle for emerging technologies, blockchain is approaching the peak. It is considered by Gartner as one of the ‘Key platform-enabling technologies to track.’ While there is a lot of ‘hype vs reality’ discussions going on, there is no arguing that blockchain is b...
In his keynote at 18th Cloud Expo, Andrew Keys, Co-Founder of ConsenSys Enterprise, provided an overview of the evolution of the Internet and the Database and the future of their combination – the Blockchain. Andrew Keys is Co-Founder of ConsenSys Enterprise. He comes to ConsenSys Enterprise with capital markets, technology and entrepreneurial experience. Previously, he worked for UBS investment bank in equities analysis. Later, he was responsible for the creation and distribution of life settle...
DevOps is under attack because developers don’t want to mess with infrastructure. They will happily own their code into production, but want to use platforms instead of raw automation. That’s changing the landscape that we understand as DevOps with both architecture concepts (CloudNative) and process redefinition (SRE). Rob Hirschfeld’s recent work in Kubernetes operations has led to the conclusion that containers and related platforms have changed the way we should be thinking about DevOps and...
The need for greater agility and scalability necessitated the digital transformation in the form of following equation: monolithic to microservices to serverless architecture (FaaS). To keep up with the cut-throat competition, the organisations need to update their technology stack to make software development their differentiating factor. Thus microservices architecture emerged as a potential method to provide development teams with greater flexibility and other advantages, such as the abili...
Product connectivity goes hand and hand these days with increased use of personal data. New IoT devices are becoming more personalized than ever before. In his session at 22nd Cloud Expo | DXWorld Expo, Nicolas Fierro, CEO of MIMIR Blockchain Solutions, will discuss how in order to protect your data and privacy, IoT applications need to embrace Blockchain technology for a new level of product security never before seen - or needed.
Leading companies, from the Global Fortune 500 to the smallest companies, are adopting hybrid cloud as the path to business advantage. Hybrid cloud depends on cloud services and on-premises infrastructure working in unison. Successful implementations require new levels of data mobility, enabled by an automated and seamless flow across on-premises and cloud resources. In his general session at 21st Cloud Expo, Greg Tevis, an IBM Storage Software Technical Strategist and Customer Solution Architec...
Coca-Cola’s Google powered digital signage system lays the groundwork for a more valuable connection between Coke and its customers. Digital signs pair software with high-resolution displays so that a message can be changed instantly based on what the operator wants to communicate or sell. In their Day 3 Keynote at 21st Cloud Expo, Greg Chambers, Global Group Director, Digital Innovation, Coca-Cola, and Vidya Nagarajan, a Senior Product Manager at Google, discussed how from store operations and ...
"As we've gone out into the public cloud we've seen that over time we may have lost a few things - we've lost control, we've given up cost to a certain extent, and then security, flexibility," explained Steve Conner, VP of Sales at Cloudistics,in this SYS-CON.tv interview at 20th Cloud Expo, held June 6-8, 2017, at the Javits Center in New York City, NY.
Blockchain is a shared, secure record of exchange that establishes trust, accountability and transparency across business networks. Supported by the Linux Foundation's open source, open-standards based Hyperledger Project, Blockchain has the potential to improve regulatory compliance, reduce cost as well as advance trade. Are you curious about how Blockchain is built for business? In her session at 21st Cloud Expo, René Bostic, Technical VP of the IBM Cloud Unit in North America, discussed the b...
The use of containers by developers -- and now increasingly IT operators -- has grown from infatuation to deep and abiding love. But as with any long-term affair, the honeymoon soon leads to needing to live well together ... and maybe even getting some relationship help along the way. And so it goes with container orchestration and automation solutions, which are rapidly emerging as the means to maintain the bliss between rapid container adoption and broad container use among multiple cloud host...
In his session at 21st Cloud Expo, Michael Burley, a Senior Business Development Executive in IT Services at NetApp, described how NetApp designed a three-year program of work to migrate 25PB of a major telco's enterprise data to a new STaaS platform, and then secured a long-term contract to manage and operate the platform. This significant program blended the best of NetApp’s solutions and services capabilities to enable this telco’s successful adoption of private cloud storage and launching ...
You know you need the cloud, but you’re hesitant to simply dump everything at Amazon since you know that not all workloads are suitable for cloud. You know that you want the kind of ease of use and scalability that you get with public cloud, but your applications are architected in a way that makes the public cloud a non-starter. You’re looking at private cloud solutions based on hyperconverged infrastructure, but you’re concerned with the limits inherent in those technologies.
Imagine if you will, a retail floor so densely packed with sensors that they can pick up the movements of insects scurrying across a store aisle. Or a component of a piece of factory equipment so well-instrumented that its digital twin provides resolution down to the micrometer.
"Since we launched LinuxONE we learned a lot from our customers. More than anything what they responded to were some very unique security capabilities that we have," explained Mark Figley, Director of LinuxONE Offerings at IBM, in this SYS-CON.tv interview at 21st Cloud Expo, held Oct 31 – Nov 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA.
Is advanced scheduling in Kubernetes achievable?Yes, however, how do you properly accommodate every real-life scenario that a Kubernetes user might encounter? How do you leverage advanced scheduling techniques to shape and describe each scenario in easy-to-use rules and configurations? In his session at @DevOpsSummit at 21st Cloud Expo, Oleg Chunikhin, CTO at Kublr, answered these questions and demonstrated techniques for implementing advanced scheduling. For example, using spot instances and co...