Welcome!

News Feed Item

NAS911 Being Evaluated as Co-Therapeutic for Treatment of Influenza

SCOTTSDALE, AZ -- (Marketwired) -- 08/06/14 -- New Amsterdam Sciences (NAS), an emerging bioscience company focused on treating respiratory illnesses, announced today the completion of initial confirmatory studies in animal models designating Oseltamivir (Tamiflu) and NAS' lead compound NAS911 as a co-therapeutic for existing influenza antivirals currently available to flu patients. Tamiflu is presently the gold standard for prevention or inhibition of the spread of influenza virus A and B.

Studies were conducted through the Therapeutics Development Services program of the National Institute of Allergy and Infectious Diseases (NIAID), a part of the National Institutes of Health (NIH). The goal of the research is to identify and advance the development of a co-therapeutic for existing antivirals for influenza. To date, New Amsterdam Sciences has explored the use of NAS911F in a multitude of different preclinical FDA accepted influenza infection models. Studies conducted by the company through third party facilities has demonstrated that NAS911F is shown to be a more effective treatment candidate than Tamiflu in side-by-side animal model comparison studies with end points of duration of flu, symptoms and other key factors supporting the work. An upcoming planned study for NAS is a co-therapeutic study combining Roche's TamiFlu with NAS's NAS911F with expectations of data demonstrating greater efficacy of TamiFlu combined with NAS911F as a combinatory influenza treatment. "Having the development interest and support from DMID for our flu candidate is extremely promising for our prospect pharma partnerships," said Michael Wilhelm, Director of Strategic Partnering. "This aids in the advancement of the most effective flu treatments currently available or in development." NAS is confident the co-therapeutic candidate will not only be more effective at the first symptom of flu but on severe and late stage flu cases as well. The company has explored seasonal and pandemic strains, observing reductions of morbidity and mortality in all models tested. NAS is currently exploring testing with additional influenza strains, including H7N9. These studies would to further explore the ideal dosing regimen for a clinical trial, as well as defining the mechanism of action of NAS911F in these models. NAS911F is a host-targeted immunomodulatory with a significant breadth and depth of safety and efficacy in the dozens of models tested to date.

"Working with the NIH's Influenza Therapeutics Development Program is a serious boon to the development of New Amsterdam Sciences' novel influenza therapeutic, NAS911F," said Jerry Toepfer, Vice President of NAS. "We anticipate this relationship will be an enormous leverage of time and money for our research, directly leading to our clinical trial objectives."

About the National Institute of Allergy and Infectious Diseases (NIAID)

NIAID conducts and supports research -- at NIH, throughout the United States, and worldwide -- to study the causes of infectious and immune-mediated diseases, and to develop better means of preventing, diagnosing and treating these illnesses. News releases, fact sheets and other NIAID-related materials are available on the NIAID Web site at www.niaid.nih.gov.

About New Amsterdam Sciences

New Amsterdam Sciences is a development-stage bioscience company focused on the research, development and licensing of analogues of Substance P. The company's lead compound is NAS911, which is being pursued for indications including idiopathic pulmonary fibrosis, influenza infection, radiation sickness, and solid tumors. New Amsterdam Sciences is devoted to developing products for both the commercial and government markets, focusing specifically on mass casualty biodefense applications. To complete this mission, the company has cultivated numerous study partnerships with industry and academic leaders, including the Vaccine and Gene Therapy Institute of Florida, the University of Rochester, BARDA, NIH and more. For additional information, please visit www.newamsterdamsciences.com.

Image Available: http://www2.marketwire.com/mw/frame_mw?attachid=2652208

CORPORATE CONTACT:
Investor and Corporate Relations
Michael K. Wilhelm
480-477-7735
Email Contact
Email Contact

MEDIA CONTACT:
Dan Spelling
310-838-4010
Email Contact

More Stories By Marketwired .

Copyright © 2009 Marketwired. All rights reserved. All the news releases provided by Marketwired are copyrighted. Any forms of copying other than an individual user's personal reference without express written permission is prohibited. Further distribution of these materials is strictly forbidden, including but not limited to, posting, emailing, faxing, archiving in a public database, redistributing via a computer network or in a printed form.

Latest Stories
With major technology companies and startups seriously embracing Cloud strategies, now is the perfect time to attend 21st Cloud Expo October 31 - November 2, 2017, at the Santa Clara Convention Center, CA, and June 12-14, 2018, at the Javits Center in New York City, NY, and learn what is going on, contribute to the discussions, and ensure that your enterprise is on the right path to Digital Transformation.
Cloud Expo, Inc. has announced today that Andi Mann and Aruna Ravichandran have been named Co-Chairs of @DevOpsSummit at Cloud Expo Silicon Valley which will take place Oct. 31-Nov. 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA. "DevOps is at the intersection of technology and business-optimizing tools, organizations and processes to bring measurable improvements in productivity and profitability," said Aruna Ravichandran, vice president, DevOps product and solutions marketing...
Digital transformation is changing the face of business. The IDC predicts that enterprises will commit to a massive new scale of digital transformation, to stake out leadership positions in the "digital transformation economy." Accordingly, attendees at the upcoming Cloud Expo | @ThingsExpo at the Santa Clara Convention Center in Santa Clara, CA, Oct 31-Nov 2, will find fresh new content in a new track called Enterprise Cloud & Digital Transformation.
Most technology leaders, contemporary and from the hardware era, are reshaping their businesses to do software. They hope to capture value from emerging technologies such as IoT, SDN, and AI. Ultimately, irrespective of the vertical, it is about deriving value from independent software applications participating in an ecosystem as one comprehensive solution. In his session at @ThingsExpo, Kausik Sridhar, founder and CTO of Pulzze Systems, will discuss how given the magnitude of today's applicati...
Smart cities have the potential to change our lives at so many levels for citizens: less pollution, reduced parking obstacles, better health, education and more energy savings. Real-time data streaming and the Internet of Things (IoT) possess the power to turn this vision into a reality. However, most organizations today are building their data infrastructure to focus solely on addressing immediate business needs vs. a platform capable of quickly adapting emerging technologies to address future ...
SYS-CON Events announced today that mruby Forum will exhibit at the Japan External Trade Organization (JETRO) Pavilion at SYS-CON's 21st International Cloud Expo®, which will take place on Oct 31 – Nov 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA. mruby is the lightweight implementation of the Ruby language. We introduce mruby and the mruby IoT framework that enhances development productivity. For more information, visit http://forum.mruby.org/.
The dynamic nature of the cloud means that change is a constant when it comes to modern cloud-based infrastructure. Delivering modern applications to end users, therefore, is a constantly shifting challenge. Delivery automation helps IT Ops teams ensure that apps are providing an optimal end user experience over hybrid-cloud and multi-cloud environments, no matter what the current state of the infrastructure is. To employ a delivery automation strategy that reflects your business rules, making r...
SYS-CON Events announced today that NetApp has been named “Bronze Sponsor” of SYS-CON's 21st International Cloud Expo®, which will take place on Oct 31 – Nov 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA. NetApp is the data authority for hybrid cloud. NetApp provides a full range of hybrid cloud data services that simplify management of applications and data across cloud and on-premises environments to accelerate digital transformation. Together with their partners, NetApp emp...
In his general session at 21st Cloud Expo, Greg Dumas, Calligo’s Vice President and G.M. of US operations, will go over the new Global Data Protection Regulation and how Calligo can help business stay compliant in digitally globalized world. Greg Dumas is Calligo's Vice President and G.M. of US operations. Calligo is an established service provider that provides an innovative platform for trusted cloud solutions. Calligo’s customers are typically most concerned about GDPR compliance, applicatio...
In a recent survey, Sumo Logic surveyed 1,500 customers who employ cloud services such as Amazon Web Services (AWS), Microsoft Azure, and Google Cloud Platform (GCP). According to the survey, a quarter of the respondents have already deployed Docker containers and nearly as many (23 percent) are employing the AWS Lambda serverless computing framework. It’s clear: serverless is here to stay. The adoption does come with some needed changes, within both application development and operations. Tha...
Enterprises are adopting Kubernetes to accelerate the development and the delivery of cloud-native applications. However, sharing a Kubernetes cluster between members of the same team can be challenging. And, sharing clusters across multiple teams is even harder. Kubernetes offers several constructs to help implement segmentation and isolation. However, these primitives can be complex to understand and apply. As a result, it’s becoming common for enterprises to end up with several clusters. Thi...
Data scientists must access high-performance computing resources across a wide-area network. To achieve cloud-based HPC visualization, researchers must transfer datasets and visualization results efficiently. HPC clusters now compute GPU-accelerated visualization in the cloud cluster. To efficiently display results remotely, a high-performance, low-latency protocol transfers the display from the cluster to a remote desktop. Further, tools to easily mount remote datasets and efficiently transfer...
Though cloud is the future of enterprise computing, a smooth transition of legacy applications and systems is critical for seamless business operations. IT professionals are eager to start leveraging the cost, scale and other benefits of cloud, but with massive investments already in place in existing infrastructure and a number of compliance and resource hurdles, it can be challenging to move to a cloud-based infrastructure.
SYS-CON Events announced today that Avere Systems, a leading provider of enterprise storage for the hybrid cloud, will exhibit at SYS-CON's 21st International Cloud Expo®, which will take place on Oct 31 - Nov 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA. Avere delivers a more modern architectural approach to storage that doesn't require the overprovisioning of storage capacity to achieve performance, overspending on expensive storage media for inactive data or the overbui...
Containers are rapidly finding their way into enterprise data centers, but change is difficult. How do enterprises transform their architecture with technologies like containers without losing the reliable components of their current solutions? In his session at @DevOpsSummit at 21st Cloud Expo, Tony Campbell, Director, Educational Services at CoreOS, will explore the challenges organizations are facing today as they move to containers and go over how Kubernetes applications can deploy with lega...