Welcome!

News Feed Item

Nevro Announces Issuance of Key European & Australian Patents for Innovative Chronic Pain Treatment

-- Patents Offer Additional International Protection for Proprietary, HF10™ Spinal Cord Stimulation Therapy

MENLO PARK, California, Aug. 25, 2014 /PRNewswire/ -- Nevro Corp., a medical device company that has developed and commercialized an innovative, evidence based neuromodulation platform for the treatment of chronic pain, is pleased to announce the issuance of European and Australian patents related to the company's Senza® spinal cord stimulation system and HF10™ therapy.

European Patent No. EP 2630984 B1, titled Multi-Frequency Neural Treatments and Associated Systems, and Australian Patent No. AU 2013263724 B2, titled Selective High Frequency Spinal Cord Modulation for Inhibiting Pain with Reduced Side Effects and Associated Systems and Methods, pertain to systems for treating chronic pain by applying Nevro's proprietary HF10 therapy to a patient's spinal region. Further patent applications covering other aspects of Nevro's proprietary technology are pending in Europe and Australia.

Nevro's Senza system is currently available for sale in Europe and Australia, and is supported by a European clinical study recently published in the journal Pain Medicine. The clinical study evaluated the long term safety and efficacy of Nevro's HF10 therapy in patients with difficult-to-treat chronic, retractable back and leg pain. The two-year follow up of the open label, prospective study was conducted at two sites in Belgium and the United Kingdom. 82 chronic pain patients completed the therapy evaluation phase, or trial phase, for HF10 therapy and 72 were permanently implanted as a result of successful evaluation phase. 65 of these patients were followed to two years. Key results at two year follow-up included a reduction of the mean baseline back pain score from 8.4 out of 10.0 to 3.3 (P < 0.001) and a reduction of leg pain score from 5.4 out of 10.0 to 2.3 (P < 0.001). Furthermore, the mean dosage of oral morphine equivalents per patient decreased from 84 mg/day to 27 mg/day (P < 0.001) and disability and sleep disturbances were also significantly reduced. The results were achieved while demonstrating a safety profile for HF10 therapy that was comparable to traditional spinal cord stimulation (SCS) in terms of type and rates of complications.

"We are encouraged by the clinical results and patient outcomes achieved by HF10 therapy, and we are pleased to announce the addition of these patents to our growing intellectual property portfolio," said Nevro's CEO Michael DeMane.

About the Senza system and HF10 therapy

The Senza system is the only SCS system that delivers Nevro's proprietary HF10 therapy, an advanced SCS therapy that provides electrical pulses to the spinal cord at a rate up to 10,000 per second (10 kHz), as compared to traditional SCS, which utilizes low frequency stimulation, typically between 40 Hz and 60 Hz. HF10 therapy also differs from traditional SCS in that it provides back and leg pain relief without paresthesia, a constant tingling sensation that is the basis of traditional SCS therapy. The electrical pulses are delivered by small electrodes on leads that are placed near the spinal cord and are connected to a compact, battery-powered generator implanted under the skin. The Senza system utilizes a rechargeable battery and has at least 10 year battery life as indicated in its CE label.

In the United States, the Senza system is limited by federal law to investigational use only, and is presently the subject of the SENZA-RCT pivotal study, a prospective randomized controlled pivotal study.

About Nevro Corp.

Headquartered in Menlo Park, Calif., privately held Nevro Corp. is a medical device company that has developed an innovative, evidence based neuromodulation platform for the treatment of chronic pain. Nevro's investors include Johnson & Johnson Development Corporation, NEA, Bay City Capital, Three Arch Partners, Novo, Aberdare Ventures, MPM Capital, Covidien and Accuitive Medical Ventures. For more information visit www.nevro.com.

Senza, HF10, Nevro and the Nevro logo are trademarks of Nevro Corp.

More Stories By PR Newswire

Copyright © 2007 PR Newswire. All rights reserved. Republication or redistribution of PRNewswire content is expressly prohibited without the prior written consent of PRNewswire. PRNewswire shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.

Latest Stories
In his session at 21st Cloud Expo, James Henry, Co-CEO/CTO of Calgary Scientific Inc., introduced you to the challenges, solutions and benefits of training AI systems to solve visual problems with an emphasis on improving AIs with continuous training in the field. He explored applications in several industries and discussed technologies that allow the deployment of advanced visualization solutions to the cloud.
Widespread fragmentation is stalling the growth of the IIoT and making it difficult for partners to work together. The number of software platforms, apps, hardware and connectivity standards is creating paralysis among businesses that are afraid of being locked into a solution. EdgeX Foundry is unifying the community around a common IoT edge framework and an ecosystem of interoperable components.
Agile has finally jumped the technology shark, expanding outside the software world. Enterprises are now increasingly adopting Agile practices across their organizations in order to successfully navigate the disruptive waters that threaten to drown them. In our quest for establishing change as a core competency in our organizations, this business-centric notion of Agile is an essential component of Agile Digital Transformation. In the years since the publication of the Agile Manifesto, the conn...
"MobiDev is a software development company and we do complex, custom software development for everybody from entrepreneurs to large enterprises," explained Alan Winters, U.S. Head of Business Development at MobiDev, in this SYS-CON.tv interview at 21st Cloud Expo, held Oct 31 – Nov 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA.
Large industrial manufacturing organizations are adopting the agile principles of cloud software companies. The industrial manufacturing development process has not scaled over time. Now that design CAD teams are geographically distributed, centralizing their work is key. With large multi-gigabyte projects, outdated tools have stifled industrial team agility, time-to-market milestones, and impacted P&L stakeholders.
"ZeroStack is a startup in Silicon Valley. We're solving a very interesting problem around bringing public cloud convenience with private cloud control for enterprises and mid-size companies," explained Kamesh Pemmaraju, VP of Product Management at ZeroStack, in this SYS-CON.tv interview at 21st Cloud Expo, held Oct 31 – Nov 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA.
Enterprises are adopting Kubernetes to accelerate the development and the delivery of cloud-native applications. However, sharing a Kubernetes cluster between members of the same team can be challenging. And, sharing clusters across multiple teams is even harder. Kubernetes offers several constructs to help implement segmentation and isolation. However, these primitives can be complex to understand and apply. As a result, it’s becoming common for enterprises to end up with several clusters. Thi...
"Space Monkey by Vivent Smart Home is a product that is a distributed cloud-based edge storage network. Vivent Smart Home, our parent company, is a smart home provider that places a lot of hard drives across homes in North America," explained JT Olds, Director of Engineering, and Brandon Crowfeather, Product Manager, at Vivint Smart Home, in this SYS-CON.tv interview at @ThingsExpo, held Oct 31 – Nov 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA.
"Akvelon is a software development company and we also provide consultancy services to folks who are looking to scale or accelerate their engineering roadmaps," explained Jeremiah Mothersell, Marketing Manager at Akvelon, in this SYS-CON.tv interview at 21st Cloud Expo, held Oct 31 – Nov 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA.
In his session at 21st Cloud Expo, Carl J. Levine, Senior Technical Evangelist for NS1, will objectively discuss how DNS is used to solve Digital Transformation challenges in large SaaS applications, CDNs, AdTech platforms, and other demanding use cases. Carl J. Levine is the Senior Technical Evangelist for NS1. A veteran of the Internet Infrastructure space, he has over a decade of experience with startups, networking protocols and Internet infrastructure, combined with the unique ability to it...
"Codigm is based on the cloud and we are here to explore marketing opportunities in America. Our mission is to make an ecosystem of the SW environment that anyone can understand, learn, teach, and develop the SW on the cloud," explained Sung Tae Ryu, CEO of Codigm, in this SYS-CON.tv interview at 21st Cloud Expo, held Oct 31 – Nov 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA.
"Infoblox does DNS, DHCP and IP address management for not only enterprise networks but cloud networks as well. Customers are looking for a single platform that can extend not only in their private enterprise environment but private cloud, public cloud, tracking all the IP space and everything that is going on in that environment," explained Steve Salo, Principal Systems Engineer at Infoblox, in this SYS-CON.tv interview at 21st Cloud Expo, held Oct 31 – Nov 2, 2017, at the Santa Clara Conventio...
The question before companies today is not whether to become intelligent, it’s a question of how and how fast. The key is to adopt and deploy an intelligent application strategy while simultaneously preparing to scale that intelligence. In her session at 21st Cloud Expo, Sangeeta Chakraborty, Chief Customer Officer at Ayasdi, provided a tactical framework to become a truly intelligent enterprise, including how to identify the right applications for AI, how to build a Center of Excellence to oper...
"IBM is really all in on blockchain. We take a look at sort of the history of blockchain ledger technologies. It started out with bitcoin, Ethereum, and IBM evaluated these particular blockchain technologies and found they were anonymous and permissionless and that many companies were looking for permissioned blockchain," stated René Bostic, Technical VP of the IBM Cloud Unit in North America, in this SYS-CON.tv interview at 21st Cloud Expo, held Oct 31 – Nov 2, 2017, at the Santa Clara Conventi...
Gemini is Yahoo’s native and search advertising platform. To ensure the quality of a complex distributed system that spans multiple products and components and across various desktop websites and mobile app and web experiences – both Yahoo owned and operated and third-party syndication (supply), with complex interaction with more than a billion users and numerous advertisers globally (demand) – it becomes imperative to automate a set of end-to-end tests 24x7 to detect bugs and regression. In th...