Welcome!

News Feed Item

Brainlab: First Patient Treatment with Revolutionary New Radiosurgery Software for Multiple Brain Metastases

New Automatic Brain Metastases Planning* software by Brainlab has been clinically used to successfully deliver fast, efficient radiosurgery treatment to a patient with metastatic brain cancer. The procedure was performed at Assuta Hospital in Tel Aviv, where clinicians treated a patient with multiple metastases during a single fraction, 20-minute radiosurgery session with only six minutes of ‘beam-on’ time, establishing a new benchmark in treatment consistency, conformity and efficiency.

Assuta Hospital used the Brainlab software to plan and deliver treatment to a 62-year-old female patient with breast cancer. The breast cancer had metastasized to the patient’s brain and she previously responded to treatment with whole brain radiotherapy (WBRT). Nine months later, her metastases recurred and her radiotherapy team at Assuta was able to use Brainlab Automatic Brain Metastases Planning software to treat all four of her metastases in a single twenty-minute session.

“The Brainlab software is unparalleled in the market,” explained Roberto Spiegelmann, MD, Neurosurgeon and Senior Advisor in Radiosurgery, Assuta Hospital. “The automated planning and delivery streamlines the entire process while the proprietary treatment algorithm allows us to treat simultaneously a number of metastases with optimal dose to the tumors and extremely limited dose spill to surrounding healthy tissue. This multiple metastases software will impact the way brain metastases are treated with radiosurgery from now on.”

The Brainlab Automatic Brain Metastases Planning provides a very fast planning and delivery solution resulting in a very conformal and ‘monitor-unit-efficient’ treatment of multiple metastases. Through intelligent manipulation of linear accelerator ‘leaf’ mechanics, the time-efficient technology allows for precision targeting of several metastases in a single session, taking full advantage of the rotation of the machine to deliver a conformity-optimized plan. Clinicians can achieve very tight dose conformity around each tumor, helping reduce side effects that can occur when healthy tissue is exposed to excess radiation.

“I wish I had this tool months ago and not had treated this patient with whole-brain radiation,” said Dr. Spiegelmann. “Her cancer is evidently aggressive enough and managed to come back despite the hope of disease spread prevention under a simple WBRT paradigm. With the help of this software, we can now offer our patients a new way of treating their tumors locally, with aggressive curative doses, regardless of how resilient the disease may be and irrespective of the tumor numbers. I am confident that offering more upfront stereotactic radiosurgery treatments will increase our patients' functional preservation and retain quality of life, and that we could push WBRT further out in their treatment cycle and use it only when and if necessary.”

"This new planning software complements other Brainlab innovations of recent years, in particular frameless stereotactic radiotherapy and ExacTrac®1 positioning which have allowed our patients precision brain radiosurgery without requiring a rigid frame screwed into the skull2,” explained Raphael Pfeffer, MD, Director of the Oncology Institute at Assuta and longtime partner with Dr. Spiegelmann and physicist, Daphne Levin, PhD, in neuro-radiotherapy. The new software improves the planning of radiosurgery for multiple brain metastases such that each treatment arc covers many metastases, thereby also helping to improve patient comfort by shortening the treatment delivery time. For our patient with four metastases, treatment was completed in 20 minutes compared to more than 60 minutes duration previously. This new software is opportune and comes at a time when the paradigm of treatment of multiple brain metastases is shifting from whole brain radiotherapy to stereotactic treatment of the metastases whilst reducing toxicity to normal brain. This week we are already treating our third patient with multiple brain metastases with the new software."

“Clinical use of this technology represents a significant paradigm shift for patients with brain metastases,” said Stefan Vilsmeier, CEO and Founder, Brainlab. “The Automatic Brain Metastases Planning software effectively articulates the Brainlab vision of indication-specific and highly automated software applications aimed at transforming practice patterns in radiosurgery. We are continuously building on our 25 years of experience in rethinking radiosurgery and this is one of many more innovations to come."

To learn more, visit Brainlab.com/brainmets.

About Assuta Medical Center

Assuta is Israel’s largest and leading private medical services center, comprising eleven clinics and hospitals across Israel and providing innovative surgeries and diagnostic procedures in all fields of medicine, including cardiology, oncology, gynecology, urology and more.

Assuta Hospital in Tel-Aviv was established in 1934, and over the past 70 years has become renowned as the most advanced hospital in the Middle East.

About Brainlab

Brainlab, headquartered in Munich, develops, manufactures and markets software-driven medical technology, enabling access to and consistency of advanced, less invasive patient treatment.

Core products revolve around information-guided surgery, precision radiation therapy, and information and knowledge sharing that fosters interdisciplinary collaboration. Brainlab technology currently powers treatments in the fields of neurosurgery, radiosurgery/radiotherapy, orthopedics, ENT, CMF, spine, and trauma.

Privately held since its formation in 1989, Brainlab has more than 5,000 systems installed in about 95 countries. Brainlab employs 1,150 people in 17 offices worldwide, including 290 research & development engineers, who form a crucial part of the product development team.

To learn more, visit www.brainlab.com.

* FDA clearance pending

1 Registered trademark of Brainlab AG in Germany and the US

2 Some doctors may opt for a minimally invasive head frame depending on the specific treatment and patient.

More Stories By Business Wire

Copyright © 2009 Business Wire. All rights reserved. Republication or redistribution of Business Wire content is expressly prohibited without the prior written consent of Business Wire. Business Wire shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.

Latest Stories
Smart Cities are here to stay, but for their promise to be delivered, the data they produce must not be put in new siloes. In his session at @ThingsExpo, Mathias Herberts, Co-founder and CTO of Cityzen Data, discussed the best practices that will ensure a successful smart city journey.
WebRTC sits at the intersection between VoIP and the Web. As such, it poses some interesting challenges for those developing services on top of it, but also for those who need to test and monitor these services. In his session at WebRTC Summit, Tsahi Levent-Levi, co-founder of testRTC, reviewed the various challenges posed by WebRTC when it comes to testing and monitoring and on ways to overcome them.
For basic one-to-one voice or video calling solutions, WebRTC has proven to be a very powerful technology. Although WebRTC’s core functionality is to provide secure, real-time p2p media streaming, leveraging native platform features and server-side components brings up new communication capabilities for web and native mobile applications, allowing for advanced multi-user use cases such as video broadcasting, conferencing, and media recording.
The best-practices for building IoT applications with Go Code that attendees can use to build their own IoT applications. In his session at @ThingsExpo, Indraneel Mitra, Senior Solutions Architect & Technology Evangelist at Cognizant, provided valuable information and resources for both novice and experienced developers on how to get started with IoT and Golang in a day. He also provided information on how to use Intel Arduino Kit, Go Robotics API and AWS IoT stack to build an application tha...
All organizations that did not originate this moment have a pre-existing culture as well as legacy technology and processes that can be more or less amenable to DevOps implementation. That organizational culture is influenced by the personalities and management styles of Executive Management, the wider culture in which the organization is situated, and the personalities of key team members at all levels of the organization. This culture and entrenched interests usually throw a wrench in the work...
Every successful software product evolves from an idea to an enterprise system. Notably, the same way is passed by the product owner's company. In his session at 20th Cloud Expo, Oleg Lola, CEO of MobiDev, will provide a generalized overview of the evolution of a software product, the product owner, the needs that arise at various stages of this process, and the value brought by a software development partner to the product owner as a response to these needs.
"Plutora provides release and testing environment capabilities to the enterprise," explained Dalibor Siroky, Director and Co-founder of Plutora, in this SYS-CON.tv interview at @DevOpsSummit, held June 9-11, 2015, at the Javits Center in New York City.
SYS-CON Events announced today that Enzu will exhibit at SYS-CON's 20th International Cloud Expo®, which will take place on June 6-8, 2017, at the Javits Center in New York City, NY, and the 21st International Cloud Expo®, which will take place October 31-November 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA. Enzu’s mission is to be the leading provider of enterprise cloud solutions worldwide. Enzu enables online businesses to use its IT infrastructure to their competitive ad...
In his session at DevOps Summit, Tapabrata Pal, Director of Enterprise Architecture at Capital One, will tell a story about how Capital One has embraced Agile and DevOps Security practices across the Enterprise – driven by Enterprise Architecture; bringing in Development, Operations and Information Security organizations together. Capital Ones DevOpsSec practice is based upon three "pillars" – Shift-Left, Automate Everything, Dashboard Everything. Within about three years, from 100% waterfall, C...
SYS-CON Events announced today that MobiDev, a client-oriented software development company, will exhibit at SYS-CON's 20th International Cloud Expo®, which will take place June 6-8, 2017, at the Javits Center in New York City, NY, and the 21st International Cloud Expo®, which will take place October 31-November 2, 2017, at the Santa Clara Convention Center in Santa Clara, CA. MobiDev is a software company that develops and delivers turn-key mobile apps, websites, web services, and complex softw...
DevOps is being widely accepted (if not fully adopted) as essential in enterprise IT. But as Enterprise DevOps gains maturity, expands scope, and increases velocity, the need for data-driven decisions across teams becomes more acute. DevOps teams in any modern business must wrangle the ‘digital exhaust’ from the delivery toolchain, "pervasive" and "cognitive" computing, APIs and services, mobile devices and applications, the Internet of Things, and now even blockchain. In this power panel at @...
Internet of @ThingsExpo, taking place June 6-8, 2017 at the Javits Center in New York City, New York, is co-located with the 20th International Cloud Expo and will feature technical sessions from a rock star conference faculty and the leading industry players in the world. @ThingsExpo New York Call for Papers is now open.
In his session at 19th Cloud Expo, Claude Remillard, Principal Program Manager in Developer Division at Microsoft, contrasted how his team used config as code and immutable patterns for continuous delivery of microservices and apps to the cloud. He showed how the immutable patterns helps developers do away with most of the complexity of config as code-enabling scenarios such as rollback, zero downtime upgrades with far greater simplicity. He also demoed building immutable pipelines in the cloud ...
SYS-CON Events announced today that Catchpoint Systems, Inc., a provider of innovative web and infrastructure monitoring solutions, has been named “Silver Sponsor” of SYS-CON's DevOps Summit at 18th Cloud Expo New York, which will take place June 7-9, 2016, at the Javits Center in New York City, NY. Catchpoint is a leading Digital Performance Analytics company that provides unparalleled insight into customer-critical services to help consistently deliver an amazing customer experience. Designed ...
Web Real-Time Communication APIs have quickly revolutionized what browsers are capable of. In addition to video and audio streams, we can now bi-directionally send arbitrary data over WebRTC's PeerConnection Data Channels. With the advent of Progressive Web Apps and new hardware APIs such as WebBluetooh and WebUSB, we can finally enable users to stitch together the Internet of Things directly from their browsers while communicating privately and securely in a decentralized way.