News Feed Item
Needle-Free Delivery Devices Shape the Future of Vaccines, Says Frost & Sullivan
Emerging technologies will include 'smaller than a fingernail' nanopatch vaccines
|By PR Newswire
|September 2, 2014 04:55 AM EDT
LONDON, Sept. 2, 2014 /PRNewswire/ -- Drug delivery technologies that improve access and overall efficacy are becoming an essential part of the entire drug development process. Pharmaceutical companies are particularly investing billions of dollars in new vaccine delivery technologies in a bid to move away from needles and syringes to skin delivery procedures.
New analysis from Frost & Sullivan, Needle-Free Nanopatch Vaccines, finds that though the needle-free delivery sector currently makes up a small fraction of the total drug delivery market, the next five to ten years will see transdermal and intradermal systems (patches and degradable implants), fast-dissolving tablet vaccines, inhalers, and pulmonary delivery methods change the vaccine industry.
While certain forms of needle-free vaccines, such as liquid jet injection, gene guns and micro-needles are already in use, the cell damage caused during administration and the inability to consistently and directly deliver vaccines renders such delivery methods inefficient. Nevertheless, this inefficiency opens doors for vaccine manufacturers to create and commercialise a needle-free system that is not fraught with challenges.
"The delivery of drugs through needle-free devices is gaining acceptance owing to the availability of more formulations for needle-free deliveries," said Frost & Sullivan Healthcare Research Analyst Swathi Allada. "Significant advancements have been made, most of which have centred on addressing patient comfort levels and increasing the adoption of self-injectable therapies."
The development of thermostable vaccines with a long shelf life is another area of focus for many vaccine manufacturers, especially for those marketing to nations where cold-chain storage is an issue. The nanopatch, for instance, eliminates the need for refrigeration as the thermostable vaccine is formulated in dry form, making transportation significantly cheaper than traditional needles.
The nanopatch is a micro-needle patch comprising of little, densely packed micro-projections with a defined geometry. Smaller than a postage stamp – and getting smaller – it is capable of directly depositing vaccine to thousands of skin immune cells without causing damage to the cell membrane in the process.
"The nanopatch achieves precise, controlled and consistent skin penetration along with rapid dissolution and diffusion of the vaccine," noted Allada. "Early stage tests conducted on mouse models have shown that the nanopatch-delivered flu vaccine is effective even with 1/150th of the dose normally given through a traditional syringe."
With successful testing in animals, clinical trials on humans will need to be wrapped up to attain Food and Drug Administration approval. Once this happens, the technology will rapidly gain traction both among patients and physicians, ultimately changing the course of vaccine delivery globally.
For more information on this study, please email Anna Zanchi, Corporate Communications, at [email protected]
This Market Insight, Needle-Free Nanopatch Vaccines, is part of the Advanced Medical Technologies Growth Partnership Service program. The Insight covers a range of needle-free vaccine deliveries, discussing drivers for adoption and application scope. The study also details the development and potential of the nanopatch as well as its impact on the vaccine industry.
About Frost & Sullivan
Frost & Sullivan, the Growth Partnership Company, works in collaboration with clients to leverage visionary innovation that addresses the global challenges and related growth opportunities that will make or break today's market participants. For more than 50 years, we have been developing growth strategies for the global 1000, emerging businesses, the public sector and the investment community. Is your organization prepared for the next profound wave of industry convergence, disruptive technologies, increasing competitive intensity, Mega Trends, breakthrough best practices, changing customer dynamics and emerging economies?
Corporate Communications – Europe
P: +39.02.4851 6133
E: [email protected]
Logo - http://photos.prnewswire.com/prnh/20140902/141801
SOURCE Frost & Sullivan
SYS-CON Events announced today that BMC Software has been named "Siver Sponsor" of SYS-CON's 18th Cloud Expo, which will take place on June 7-9, 2015 at the Javits Center in New York, New York. BMC is a global leader in innovative software solutions that help businesses transform into digital enterprises for the ultimate competitive advantage. BMC Digital Enterprise Management is a set of innovative IT solutions designed to make digital business fast, seamless, and optimized from mainframe to mo...
May. 27, 2016 01:45 AM EDT Reads: 2,079
SYS-CON Events announced today that EastBanc Technologies will exhibit at SYS-CON's 18th International Cloud Expo®, which will take place on June 7-9, 2016, at the Javits Center in New York City, NY.
EastBanc Technologies has been working at the frontier of technology since 1999. Today, the firm provides full-lifecycle software development delivering flexible technology solutions that seamlessly integrate with existing systems – whether on premise or cloud. EastBanc Technologies partners with p...
May. 27, 2016 01:30 AM EDT Reads: 2,132
A strange thing is happening along the way to the Internet of Things, namely far too many devices to work with and manage. It has become clear that we'll need much higher efficiency user experiences that can allow us to more easily and scalably work with the thousands of devices that will soon be in each of our lives.
Enter the conversational interface revolution, combining bots we can literally talk with, gesture to, and even direct with our thoughts, with embedded artificial intelligence, wh...
May. 27, 2016 01:30 AM EDT Reads: 1,948
Companies can harness IoT and predictive analytics to sustain business continuity; predict and manage site performance during emergencies; minimize expensive reactive maintenance; and forecast equipment and maintenance budgets and expenditures.
Providing cost-effective, uninterrupted service is challenging, particularly for organizations with geographically dispersed operations.
May. 27, 2016 01:00 AM EDT Reads: 1,874
SYS-CON Events announced today that Isomorphic Software will exhibit at SYS-CON's [email protected]
at Cloud Expo New York, which will take place on June 7-9, 2016, at the Javits Center in New York City, NY.
Isomorphic Software provides the SmartClient HTML5/AJAX platform, the most advanced technology for building rich, high-productivity enterprise web applications for any device.
SmartClient couples the industry’s broadest, deepest UI component set with a java server framework to deliver an end-...
May. 27, 2016 01:00 AM EDT Reads: 2,049
The IoT is changing the way enterprises conduct business.
In his session at @ThingsExpo, Eric Hoffman, Vice President at EastBanc Technologies, discuss how businesses can gain an edge over competitors by empowering consumers to take control through IoT. We'll cite examples such as a Washington, D.C.-based sports club that leveraged IoT and the cloud to develop a comprehensive booking system. He'll also highlight how IoT can revitalize and restore outdated business models, making them profitable...
May. 27, 2016 12:45 AM EDT Reads: 2,769
SYS-CON Events announced today that Alert Logic, Inc., the leading provider of Security-as-a-Service solutions for the cloud, will exhibit at SYS-CON's 18th International Cloud Expo®, which will take place on June 7-9, 2016, at the Javits Center in New York City, NY.
Alert Logic, Inc., provides Security-as-a-Service for on-premises, cloud, and hybrid infrastructures, delivering deep security insight and continuous protection for customers at a lower cost than traditional security solutions. Ful...
May. 27, 2016 12:45 AM EDT Reads: 2,701
The essence of data analysis involves setting up data pipelines that consist of several operations that are chained together – starting from data collection, data quality checks, data integration, data analysis and data visualization (including the setting up of interaction paths in that visualization). In our opinion, the challenges stem from the technology diversity at each stage of the data pipeline as well as the lack of process around the analysis.
May. 27, 2016 12:15 AM EDT Reads: 1,355
SYS-CON Events announced today that Commvault, a global leader in enterprise data protection and information management, has been named “Bronze Sponsor” of SYS-CON's 18th International Cloud Expo, which will take place on June 7–9, 2016, at the Javits Center in New York City, NY, and the 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA.
Commvault is a leading provider of data protection and information management...
May. 27, 2016 12:00 AM EDT Reads: 3,030
Many banks and financial institutions are experimenting with containers in development environments, but when will they move into production? Containers are seen as the key to achieving the ultimate in information technology flexibility and agility. Containers work on both public and private clouds, and make it easy to build and deploy applications.
The challenge for regulated industries is the cost and complexity of container security compliance. VM security compliance is already challenging, ...
May. 27, 2016 12:00 AM EDT Reads: 1,203
Designing IoT applications is complex, but deploying them in a scalable fashion is even more complex. A scalable, API first IaaS cloud is a good start, but in order to understand the various components specific to deploying IoT applications, one needs to understand the architecture of these applications and figure out how to scale these components independently.
In his session at @ThingsExpo, Nara Rajagopalan is CEO of Accelerite, will discuss the fundamental architecture of IoT applications, ...
May. 27, 2016 12:00 AM EDT Reads: 1,142
SYS-CON Events announced today that Tintri Inc., a leading producer of VM-aware storage (VAS) for virtualization and cloud environments, will exhibit at the 18th International CloudExpo®, which will take place on June 7-9, 2016, at the Javits Center in New York City, New York, and the 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA.
May. 26, 2016 11:45 PM EDT Reads: 2,258
With major technology companies and startups seriously embracing IoT strategies, now is the perfect time to attend @ThingsExpo 2016 in New York and Silicon Valley. Learn what is going on, contribute to the discussions, and ensure that your enterprise is as "IoT-Ready" as it can be! Internet of @ThingsExpo, taking place Nov 3-5, 2015, at the Santa Clara Convention Center in Santa Clara, CA, is co-located with 17th Cloud Expo and will feature technical sessions from a rock star conference faculty ...
May. 26, 2016 11:30 PM EDT Reads: 2,558
As cloud and storage projections continue to rise, the number of organizations moving to the cloud is escalating and it is clear cloud storage is here to stay. However, is it secure?
Data is the lifeblood for government entities, countries, cloud service providers and enterprises alike and losing or exposing that data can have disastrous results.
There are new concepts for data storage on the horizon that will deliver secure solutions for storing and moving sensitive data around the world.
May. 26, 2016 11:00 PM EDT Reads: 1,246
SYS-CON Events announced today that MangoApps will exhibit at SYS-CON's 18th International Cloud Expo®, which will take place on June 7-9, 2016, at the Javits Center in New York City, NY.
MangoApps provides modern company intranets and team collaboration software, allowing workers to stay connected and productive from anywhere in the world and from any device.
For more information, please visit https://www.mangoapps.com/.
May. 26, 2016 10:45 PM EDT Reads: 682